Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S C Papasozomeno. Tau protein immunoreactivity in dementia of the Alzheimer type: II. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 3. 1989-04-28. PMID:2494388. |
tau protein immunoreactivity in dementia of the alzheimer type: ii. |
1989-04-28 |
2023-08-11 |
Not clear |
S C Papasozomeno. Tau protein immunoreactivity in dementia of the Alzheimer type: II. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 3. 1989-04-28. PMID:2494388. |
i have used tau-1 and tau-2, two monoclonal antibodies against tau protein, to study at the electron microscopic level the tau immunoreactivity in 8 cases with dementia of the alzheimer type, using the peroxidase-antiperoxidase technique and formalin-fixed autopsy and biopsy brain tissues. |
1989-04-28 |
2023-08-11 |
Not clear |
S C Papasozomeno. Tau protein immunoreactivity in dementia of the Alzheimer type. I. Morphology, evolution, distribution, and pathogenetic implications. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 1. 1989-02-17. PMID:2492060. |
tau protein immunoreactivity in dementia of the alzheimer type. |
1989-02-17 |
2023-08-11 |
Not clear |
S C Papasozomeno. Tau protein immunoreactivity in dementia of the Alzheimer type. I. Morphology, evolution, distribution, and pathogenetic implications. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 1. 1989-02-17. PMID:2492060. |
the author has used two monoclonal antibodies against tau, tau-1 and tau-2, to study at the light microscopic level the morphology, evolution, and distribution of tau immunoreactivity in 21 cases with dementia of the alzheimer type (dat) with clinical histories of dementia ranging from 6 months to 10-15 years. |
1989-02-17 |
2023-08-11 |
Not clear |
S C Papasozomeno. Tau protein immunoreactivity in dementia of the Alzheimer type. I. Morphology, evolution, distribution, and pathogenetic implications. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 1. 1989-02-17. PMID:2492060. |
the morphology and distribution of tau immunoreactivity was similar in all three forms of dat, but the rapidity of evolution, as judged by the duration of dementia and the amount of immunoreactivity, was most severe in ds with dementia and least severe in sdat. |
1989-02-17 |
2023-08-11 |
Not clear |
C Bancher, H Lassmann, H Budka, I Grundke-Iqbal, K Iqbal, G Wiche, F Seitelberger, H M Wisniewsk. Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences. Microtubule-associated protein tau antigenicity is prominent in all types of tangles. Acta neuropathologica. vol 74. issue 1. 1987-10-27. PMID:2444063. |
the antigenic profile of neurofibrillary tangles (nft) in alzheimer's disease (ad), senile dementia of alzheimer type (sdat), progressive supranuclear palsy (psp) and in non-demented aged humans was investigated by light and electron microscopic immunocytochemistry using antisera and monoclonal antibodies to tubulin, microtubule-associated proteins (map1, map2 and tau), neurofilament proteins and determinants unique to alzheimer paired helical filaments (phf). |
1987-10-27 |
2023-08-11 |
Not clear |