| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Timothy D Griffiths, Meher Lad, Sukhbinder Kumar, Emma Holmes, Bob McMurray, Eleanor A Maguire, Alexander J Billig, William Sedle. How Can Hearing Loss Cause Dementia? Neuron. vol 108. issue 3. 2020-12-28. PMID:32871106. |
in particular, we consider how aberrant activity in the service of auditory pattern analysis, working memory, and object processing may interact with dementia pathology in people with hearing loss. |
2020-12-28 |
2023-08-13 |
Not clear |
| Takashi Tarumi, Binu P Thomas, Benjamin Y Tseng, Ciwen Wang, Kyle B Womack, Linda Hynan, Hanzhang Lu, C Munro Cullum, Rong Zhan. Cerebral White Matter Integrity in Amnestic Mild Cognitive Impairment: A 1-Year Randomized Controlled Trial of Aerobic Exercise Training. Journal of Alzheimer's disease : JAD. vol 73. issue 2. 2020-11-18. PMID:31796677. |
aerobic exercise training (aet) may improve wm integrity in cognitively normal older adults, but its efficacy remains unknown in patients with amnestic mild cognitive impairment (mci), a prodromal phase of ad dementia. |
2020-11-18 |
2023-08-13 |
Not clear |
| Roy P C Kessels, Anouk Overbeek, Zita Bouma. Assessment of verbal and visuospatial working memory in mild cognitive impairment and Alzheimer's dementia. Dementia & neuropsychologia. vol 9. issue 3. 2020-10-01. PMID:29213976. |
in addition to episodic memory impairment, working memory may also be compromised in mild cognitive impairment (mci) or alzheimer's dementia (ad), but standard verbal and visuospatial span tasks do not always detect impairments. |
2020-10-01 |
2023-08-13 |
Not clear |
| Patrick Fissler, Hans-Peter Müller, Olivia C Küster, Daria Laptinskaya, Franka Thurm, Alexander Woll, Thomas Elbert, Jan Kassubek, Christine A F von Arnim, Iris-Tatjana Kolass. No Evidence That Short-Term Cognitive or Physical Training Programs or Lifestyles Are Related to Changes in White Matter Integrity in Older Adults at Risk of Dementia. Frontiers in human neuroscience. vol 11. 2020-09-30. PMID:28373835. |
in an observational and interventional pretest, posttest, 3-month follow-up design, we assigned 47 community-dwelling older adults at risk of dementia to 50 sessions of auditory processing and working memory training ( |
2020-09-30 |
2023-08-13 |
Not clear |
| Michelle S Goodman, Sanjeev Kumar, Reza Zomorrodi, Zaid Ghazala, Amay S M Cheam, Mera S Barr, Zafiris J Daskalakis, Daniel M Blumberger, Corinne Fischer, Alastair Flint, Linda Mah, Nathan Herrmann, Christopher R Bowie, Benoit H Mulsant, Tarek K Rajj. Theta-Gamma Coupling and Working Memory in Alzheimer's Dementia and Mild Cognitive Impairment. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29713274. |
theta-gamma coupling and working memory in alzheimer's dementia and mild cognitive impairment. |
2020-09-30 |
2023-08-13 |
human |
| Michelle S Goodman, Sanjeev Kumar, Reza Zomorrodi, Zaid Ghazala, Amay S M Cheam, Mera S Barr, Zafiris J Daskalakis, Daniel M Blumberger, Corinne Fischer, Alastair Flint, Linda Mah, Nathan Herrmann, Christopher R Bowie, Benoit H Mulsant, Tarek K Rajj. Theta-Gamma Coupling and Working Memory in Alzheimer's Dementia and Mild Cognitive Impairment. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29713274. |
working memory deficits are common among individuals with alzheimer's dementia (ad) or mild cognitive impairment (mci). |
2020-09-30 |
2023-08-13 |
human |
| David C Hess, Mohammad B Khan, Nasrul Hoda, John C Morga. Remote ischemic conditioning: a treatment for vascular cognitive impairment. Brain circulation. vol 1. issue 2. 2020-09-30. PMID:30221201. |
other than management of vascular risk factors, there is no treatment for wm damage and vci that delays progression of the disease process to dementia. |
2020-09-30 |
2023-08-13 |
human |
| Shanna L Burke, Mitra Naseh, Miriam J Rodriguez, Aaron Burgess, David Loewenstei. Dementia-Related Neuropsychological Testing Considerations in Non-Hispanic White and Latino/Hispanic Populations. Psychology & neuroscience. vol 12. issue 2. 2020-09-30. PMID:31649798. |
twenty-nine instruments were evaluated in dementia staging, global cognition, memory, memory and visual abilities, working memory and attention, verbal learning and memory, recall, language, premorbid intelligence, literacy/cognitive reserve, visuospatial, attention, problem-solving, problem solving and perception, functional assessment, and mood/daily functioning domains. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yoshiki Hase, Tuomo M Polvikoski, Michael J Firbank, Lucinda J L Craggs, Emily Hawthorne, Charlotte Platten, William Stevenson, Vincent Deramecourt, Clive Ballard, Rose Anne Kenny, Robert H Perry, Paul Ince, Roxana O Carare, Louise M Allan, Karen Horsburgh, Raj N Kalari. Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction. Brain pathology (Zurich, Switzerland). vol 30. issue 1. 2020-09-29. PMID:31357238. |
sclerotic index values were increased by ~50% in both the wm and neocortex in all dementias compared to similar age controls. |
2020-09-29 |
2023-08-13 |
human |
| Cameron M Clark, Veronica Guadagni, Erin L Mazerolle, Michael Hill, David B Hogan, G Bruce Pike, Marc J Pouli. Effect of aerobic exercise on white matter microstructure in the aging brain. Behavioural brain research. vol 373. 2020-09-14. PMID:31279793. |
aging is associated with decline in white matter (wm) microstructure, decreased cognitive functioning, and increased risk of alzheimer's disease and related dementias. |
2020-09-14 |
2023-08-13 |
human |
| Epameinondas Lyros, Andreas Ragoschke-Schumm, Panagiotis Kostopoulos, Alexandra Sehr, Martin Backens, Stefania Kalampokini, Yann Decker, Martin Lesmeister, Yang Liu, Wolfgang Reith, Klaus Fassbende. Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine Neurobiology of aging. vol 87. 2020-09-14. PMID:31902521. |
wm ph was low in ad and, to a lesser extent, mild cognitive impairment but not in frontotemporal dementia spectrum disorders and pure vascular dementia. |
2020-09-14 |
2023-08-13 |
human |
| Melinda C Power, Dan Su, Aozhou Wu, Robert I Reid, Clifford R Jack, David S Knopman, Joe Coresh, Juebin Huang, Kejal Kantarci, A Richey Sharrett, Rebecca G Gottesman, Mike E Griswold, Thomas H Mosle. Association of white matter microstructural integrity with cognition and dementia. Neurobiology of aging. vol 83. 2020-07-08. PMID:31585368. |
late-life measures of white matter (wm) microstructural integrity may predict cognitive status, cognitive decline, and incident mild cognitive impairment (mci) or dementia. |
2020-07-08 |
2023-08-13 |
human |
| Melinda C Power, Dan Su, Aozhou Wu, Robert I Reid, Clifford R Jack, David S Knopman, Joe Coresh, Juebin Huang, Kejal Kantarci, A Richey Sharrett, Rebecca G Gottesman, Mike E Griswold, Thomas H Mosle. Association of white matter microstructural integrity with cognition and dementia. Neurobiology of aging. vol 83. 2020-07-08. PMID:31585368. |
cross-sectionally, both overall wm fractional anisotropy and overall wm mean diffusivity were strongly associated with baseline cognitive performance and risk of prevalent mci or dementia. |
2020-07-08 |
2023-08-13 |
human |
| Melinda C Power, Dan Su, Aozhou Wu, Robert I Reid, Clifford R Jack, David S Knopman, Joe Coresh, Juebin Huang, Kejal Kantarci, A Richey Sharrett, Rebecca G Gottesman, Mike E Griswold, Thomas H Mosle. Association of white matter microstructural integrity with cognition and dementia. Neurobiology of aging. vol 83. 2020-07-08. PMID:31585368. |
increased wm mean diffusivity may provide an early indication of dementia pathogenesis. |
2020-07-08 |
2023-08-13 |
human |
| Lianne J Trigiani, Jessika Royea, Xin-Kang Tong, Edith Hame. Comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 12. 2020-06-08. PMID:31557051. |
overall, results indicate that sv and ex prevented cognitive decline in hypercholesterolemic mice and that they share common sites of action in preventing endothelial cell dysfunction and reducing wm inflammation.-trigiani, l. j., royea, j., tong, x.-k., hamel, e. comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia. |
2020-06-08 |
2023-08-13 |
mouse |
| Yoshiki Hase, Ren Ding, Gina Harrison, Emily Hawthorne, Amilia King, Sean Gettings, Charlotte Platten, William Stevenson, Lucinda J L Craggs, Raj N Kalari. White matter capillaries in vascular and neurodegenerative dementias. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30732655. |
we assessed ~ 0.7 million capillary profiles in the frontal lobe wm across several dementias comprising alzheimer's disease, dementia with lewy bodies, parkinson's disease with dementia, vascular dementia, mixed dementias, post-stroke dementia as well as post-stroke no dementia and similar age ageing and young controls without significant brain pathology. |
2020-04-02 |
2023-08-13 |
human |
| Yoshiki Hase, Ren Ding, Gina Harrison, Emily Hawthorne, Amilia King, Sean Gettings, Charlotte Platten, William Stevenson, Lucinda J L Craggs, Raj N Kalari. White matter capillaries in vascular and neurodegenerative dementias. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30732655. |
wm col4 immunopositive microvascular densities were decreased by ~ 18% across the neurodegenerative dementias. |
2020-04-02 |
2023-08-13 |
human |
| Yoshiki Hase, Ren Ding, Gina Harrison, Emily Hawthorne, Amilia King, Sean Gettings, Charlotte Platten, William Stevenson, Lucinda J L Craggs, Raj N Kalari. White matter capillaries in vascular and neurodegenerative dementias. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30732655. |
however, we found wm col4 densities were increased by ~ 57% in post-stroke dementia versus ageing and young controls and other dementias. |
2020-04-02 |
2023-08-13 |
human |
| Yoshiki Hase, Ren Ding, Gina Harrison, Emily Hawthorne, Amilia King, Sean Gettings, Charlotte Platten, William Stevenson, Lucinda J L Craggs, Raj N Kalari. White matter capillaries in vascular and neurodegenerative dementias. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30732655. |
remarkably, wm capillary widths were increased by ~ 20% across all dementias compared to ageing and young controls (p < 0.01). |
2020-04-02 |
2023-08-13 |
human |
| Yoshiki Hase, Ren Ding, Gina Harrison, Emily Hawthorne, Amilia King, Sean Gettings, Charlotte Platten, William Stevenson, Lucinda J L Craggs, Raj N Kalari. White matter capillaries in vascular and neurodegenerative dementias. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30732655. |
our key finding indicates that wm capillaries are wider compared to those in the overlying neocortex in controls but they dilate further during dementia pathogenesis. |
2020-04-02 |
2023-08-13 |
human |