Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Meng Liu, Carlos Blanco-Centurion, Roda Rani Konadhode, Liju Luan, Priyattam J Shiroman. Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin-knockout mice. The European journal of neuroscience. vol 43. issue 5. 2016-12-13. PMID:26741960. |
however, it is not known whether this method also blocks cataplexy triggered by strong emotions. |
2016-12-13 |
2023-08-13 |
mouse |
Yves Dauvilliers, Régis Lope. [NARCOLEPSY WITH CATAPLEXY: TYPE 1 NARCOLEPSY]. La Revue du praticien. vol 66. issue 6. 2016-09-22. PMID:27538328. |
the main features are excessive daytime sleepiness and cataplexy or sudden less of muscle tone triggered by emotional situations. |
2016-09-22 |
2023-08-13 |
human |
Elemer Szabad. GHB for cataplexy: Possible mode of action. Journal of psychopharmacology (Oxford, England). vol 29. issue 6. 2016-02-22. PMID:25735989. |
a troublesome symptom of narcolepsy is cataplexy, the sudden loss of muscle tone in response to strong emotions. |
2016-02-22 |
2023-08-13 |
Not clear |
Francesca Letizia Rocca, Fabio Pizza, Emilia Ricci, Giuseppe Plazz. Narcolepsy during Childhood: An Update. Neuropediatrics. vol 46. issue 3. 2016-02-16. PMID:25961600. |
children with nt1 close to disease onset show a peculiar cataplexy phenotype characterized by persistent hypotonia with prominent facial involvement (cataplectic facies) and by a complex mosaic of hyperkinetic movement abnormalities that increase during emotional stimulation. |
2016-02-16 |
2023-08-13 |
human |
Francesca Letizia Rocca, Fabio Pizza, Emilia Ricci, Giuseppe Plazz. Narcolepsy during Childhood: An Update. Neuropediatrics. vol 46. issue 3. 2016-02-16. PMID:25961600. |
this phenotype progressively vanishes along the disease course leading to the typical picture of cataplexy (i.e., muscle weakness exclusively evoked by strong emotions). |
2016-02-16 |
2023-08-13 |
human |
Todd J Swic. Treatment paradigms for cataplexy in narcolepsy: past, present, and future. Nature and science of sleep. vol 7. 2015-12-30. PMID:26715865. |
cataplexy is defined as episodes of sudden loss of voluntary muscle tone triggered by emotions generally lasting <2 minutes. |
2015-12-30 |
2023-08-13 |
human |
P H Luppi, O Clément, E Sapin, S V Garcia, C Peyron, P For. Animal models of REM dysfunctions: what they tell us about the cause of narcolepsy and RBD? Archives italiennes de biologie. vol 152. issue 2-3. 2015-11-09. PMID:25828684. |
conversely, cataplexy, one of the key symptoms of narcolepsy, is a striking sudden episode of muscle weakness triggered by emotions during wakefulness, and comparable to rem sleep atonia. |
2015-11-09 |
2023-08-13 |
Not clear |
Hassana de Almeida Fonseca, Danielle Antunes Lopes, Danielle Pereira, Danilo Anunciatto Sguillar, Eduardo Lopes, Nilce Sanny Costa da Silva Behrens, Taís Figueiredo de Araújo Lima, Marcia Pradella-Hallinan, Juliana Castro, Sergio Tufik, Fernando Morgadinho Santos Coelh. The use of citalopram for the treatment of cataplexy. Sleep science (Sao Paulo, Brazil). vol 7. issue 1. 2015-10-20. PMID:26483901. |
cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by episodes of emotion during vigil. |
2015-10-20 |
2023-08-13 |
Not clear |
Elliott Kyung Lee, Alan Bruce Douglas. Baclofen for narcolepsy with cataplexy: two cases. Nature and science of sleep. vol 7. 2015-08-07. PMID:26251634. |
those with cataplexy have spells of muscle weakness precipitated by strong emotions, especially laughter or surprise. |
2015-08-07 |
2023-08-13 |
Not clear |
Sona Nevsimalova, Vera Malinov. Cataplexy and sleep disorders in Niemann-Pick type C disease. Current neurology and neuroscience reports. vol 15. issue 1. 2015-07-17. PMID:25434476. |
in adolescent and adult patients, when intellectual deterioration progresses and emotional reactions become flat, cataplexy usually disappears. |
2015-07-17 |
2023-08-13 |
mouse |
Halime Tuna Cak, Göknur Haliloğlu, Gökçen Düzgün, Aysel Yüce, Meral Topç. Successful treatment of cataplexy in patients with early-infantile Niemann-Pick disease type C: use of tricyclic antidepressants. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 18. issue 6. 2015-07-10. PMID:25139345. |
cataplexy is a brief episode of bilateral loss of muscle tone with intact consciousness, triggered by a variety of strong emotions such as anger, laugh, humor or surprise and it is considered to represent the physiologic atonia of rapid eye movement sleep. |
2015-07-10 |
2023-08-13 |
Not clear |
Elisa Favaron, Paolo Albon. [Episodes of apparent transient loss of consciousness: disorders a cardiologist should not ignore]. Giornale italiano di cardiologia (2006). vol 16. issue 1. 2015-03-20. PMID:25689746. |
clinical findings that suggest cataplexy include an emotional trigger - above all if the emotion is positive -, an "unreal" fall similar to that observed in patients with psychogenic pseudosyncope, repeated attacks in a daytime, symptoms of narcolepsy as the clinical context. |
2015-03-20 |
2023-08-13 |
Not clear |
Massimiliano de Zambotti, Fabio Pizza, Naima Covassin, Stefano Vandi, Nicola Cellini, Luciano Stegagno, Giuseppe Plazz. Facing emotions in narcolepsy with cataplexy: haemodynamic and behavioural responses during emotional stimulation. Journal of sleep research. vol 23. issue 4. 2014-11-09. PMID:24635684. |
facing emotions in narcolepsy with cataplexy: haemodynamic and behavioural responses during emotional stimulation. |
2014-11-09 |
2023-08-12 |
Not clear |
Massimiliano de Zambotti, Fabio Pizza, Naima Covassin, Stefano Vandi, Nicola Cellini, Luciano Stegagno, Giuseppe Plazz. Facing emotions in narcolepsy with cataplexy: haemodynamic and behavioural responses during emotional stimulation. Journal of sleep research. vol 23. issue 4. 2014-11-09. PMID:24635684. |
narcolepsy with cataplexy is a complex sleep disorder that affects the modulation of emotions: cataplexy, the key symptom of narcolepsy, is indeed strongly linked with emotions that usually trigger the episodes. |
2014-11-09 |
2023-08-12 |
Not clear |
Massimiliano de Zambotti, Fabio Pizza, Naima Covassin, Stefano Vandi, Nicola Cellini, Luciano Stegagno, Giuseppe Plazz. Facing emotions in narcolepsy with cataplexy: haemodynamic and behavioural responses during emotional stimulation. Journal of sleep research. vol 23. issue 4. 2014-11-09. PMID:24635684. |
our results suggested that adult narcoleptic patients, compared with healthy controls, inhibited their emotion-expressive behaviour to emotional stimulation, and that may be related to the development of adaptive cognitive strategies to face emotions avoiding cataplexy. |
2014-11-09 |
2023-08-12 |
Not clear |
Armand Mensen, Rositsa Poryazova, Sophie Schwartz, Ramin Khatam. Humor as a reward mechanism: event-related potentials in the healthy and diseased brain. PloS one. vol 9. issue 1. 2014-09-29. PMID:24489683. |
for nc patients, humor is the strongest trigger for cataplexy, a transient loss of muscle tone, whereas dopamine-deficient pd-patients show blunted emotional responses to humor. |
2014-09-29 |
2023-08-12 |
Not clear |
Giuseppe Plazz. Dante's description of narcolepsy. Sleep medicine. vol 14. issue 11. 2014-07-08. PMID:24021161. |
taken together these signs are highly reminiscent of narcolepsy, a term coined in 1880 by gélineau to define a disease consisting of daytime irresistible sleep episodes with remarkable dream mentation, sleep paralysis, hallucinations, and cataplexy (falls triggered by strong emotions). |
2014-07-08 |
2023-08-12 |
Not clear |
Swarup Kumar, Haritha Sagil. Etiopathogenesis and neurobiology of narcolepsy: a review. Journal of clinical and diagnostic research : JCDR. vol 8. issue 2. 2014-06-24. PMID:24701532. |
this disorder is characterized by a tetrad of excessive daytime sleepiness, cataplexy (brief loss of muscle tone following strong emotion), hypnogogic hallucinations and sleep paralysis. |
2014-06-24 |
2023-08-13 |
Not clear |
Aviva Katzav, Maria T Arango, Shaye Kivity, Susumu Tanaka, Gili Givaty, Nancy Agmon-Levin, Makoto Honda, Juan-Manuel Anaya, Joab Chapman, Yehuda Shoenfel. Passive transfer of narcolepsy: anti-TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice. Journal of autoimmunity. vol 45. 2014-03-31. PMID:23834844. |
narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and cataplexy (a sudden weakening of posture muscle tone usually triggered by emotion) caused by the loss of orexin neurons in the hypothalamus. |
2014-03-31 |
2023-08-12 |
mouse |
Janice Wang, Harly Greenber. Status cataplecticus precipitated by abrupt withdrawal of venlafaxine. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 9. issue 7. 2014-03-14. PMID:23853567. |
status cataplecticus is a rare manifestation of narcolepsy with cataplexy episodes recurring for hours or days, without a refractory period, in the absence of emotional triggers. |
2014-03-14 |
2023-08-12 |
Not clear |