Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Erafat D Rehim, Martina Vendram. Cataplexy Mistaken for Seizures in a Patient With Undiagnosed Narcolepsy Type I. Cureus. vol 16. issue 4. 2024-05-06. PMID:38707044. |
cataplexy mistaken for seizures in a patient with undiagnosed narcolepsy type i. narcolepsy type 1 is a sleep disorder, with cataplexy as its cardinal feature, characterized by sudden decrease or loss of muscle tone triggered by strong emotions. |
2024-05-06 |
2024-05-08 |
Not clear |
Vinay Mandagere, Dane Raymen. Atypical isolated cataplexy: two case reports and a mini-review. Neurocase. 2024-04-27. PMID:38678310. |
cataplexy is the sudden loss of muscle tone often provoked by emotion such as laughter or excitement. |
2024-04-27 |
2024-04-30 |
Not clear |
Ram K Verma, Vinita Prasad, Subhendu Rath, Varun Monga, Gagandeep Dhillo. A Rare Presentation of Narcolepsy With Cataplexy After Vaccines in a Genetically Susceptible Elderly Woman: A Case Report. Cureus. vol 15. issue 6. 2023-07-28. PMID:37503483. |
observing cataplexy episodes during an office visit is extremely rare as they are usually triggered by laughter or emotional stress. |
2023-07-28 |
2023-08-14 |
human |
Ram K Verma, Vinita Prasad, Subhendu Rath, Varun Monga, Gagandeep Dhillo. A Rare Presentation of Narcolepsy With Cataplexy After Vaccines in a Genetically Susceptible Elderly Woman: A Case Report. Cureus. vol 15. issue 6. 2023-07-28. PMID:37503483. |
several episodes of cataplexy were observed during the office visit without any emotional trigger. |
2023-07-28 |
2023-08-14 |
human |
Brandon A Toth, Katie S Chang, Christian R Burges. Striatal dopamine regulates sleep states and narcolepsy-cataplexy. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37397994. |
patients with the sleep disorder narcolepsy suffer from excessive daytime sleepiness, disrupted nighttime sleep, and cataplexy - the abrupt loss of postural muscle tone (atonia) during wakefulness, often triggered by strong emotion. |
2023-07-03 |
2023-08-14 |
Not clear |
Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
patients with type 1 narcolepsy often also present with cataplexy, the sudden paralysis of voluntary muscles which is triggered by strong emotions (e.g., laughter in humans, social play in dogs, and chocolate in rodents). |
2023-06-02 |
2023-08-14 |
human |
Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
we propose that detailed examinations of amygdala neurocircuitry controlling transitions between emotional arousal states may substantially advance progress in understanding the etiology of narcolepsy with cataplexy, leading to enhanced treatment opportunities. |
2023-06-02 |
2023-08-14 |
human |
Paola Del Sette, Marco Veneruso, Ramona Cordani, Serena Lecce, Giorgia Varallo, Christian Franceschini, Cristina Venturino, Fabio Pizza, Giuseppe Plazzi, Lino Nobil. Narcolepsy and emotions: Is there a place for a theory of mind approach? Sleep medicine. vol 102. 2023-01-12. PMID:36634602. |
in the last two decades, researchers shed light on the neurological bases of cataplexy by focusing on the neurobiological correlates of emotions. |
2023-01-12 |
2023-08-14 |
Not clear |
Fang-Fang Fan, Vetrivelan Ramalingam, Yi Yang, Zhen-Ni Guo, Jun L. Role of pontine sub-laterodorsal tegmental nucleus (SLD) in rapid eye movement (REM) sleep, cataplexy, and emotion. CNS neuroscience & therapeutics. 2022-12-31. PMID:36585816. |
role of pontine sub-laterodorsal tegmental nucleus (sld) in rapid eye movement (rem) sleep, cataplexy, and emotion. |
2022-12-31 |
2023-08-14 |
mouse |
Fang-Fang Fan, Vetrivelan Ramalingam, Yi Yang, Zhen-Ni Guo, Jun L. Role of pontine sub-laterodorsal tegmental nucleus (SLD) in rapid eye movement (REM) sleep, cataplexy, and emotion. CNS neuroscience & therapeutics. 2022-12-31. PMID:36585816. |
however, the necessary role of sld for rem sleep, cataplexy that resembles rem sleep, and emotion memory by rem sleep has remained unclear. |
2022-12-31 |
2023-08-14 |
mouse |
Noeen Sarfraz, David Okuampa, Hannah Hansen, Mark Alvarez, Elyse M Cornett, Juyeon Kakazu, Adam M Kaye, Alan D Kay. pitolisant, a novel histamine-3 receptor competitive antagonist, and inverse agonist, in the treatment of excessive daytime sleepiness in adult patients with narcolepsy. Health psychology research. vol 10. issue 3. 2022-07-01. PMID:35774905. |
narcolepsy is a debilitating sleep disorder that presents with excessive daytime sleepiness (eds) and cataplexy, which is a sudden paralysis of muscle tone triggered by strong emotions such as laughing. |
2022-07-01 |
2023-08-14 |
Not clear |
Marco Veneruso, Fabio Pizza, Elena Finotti, Giulia Amore, Stefano Vandi, Marco Filardi, Elena Antelmi, Lino Nobili, Alessandra Cassio, Andrea Pession, Giuseppe Plazz. Child Neurology: A Case Series of Heterogeneous Neuropsychiatric Symptoms and Outcome in Very Early-Onset Narcolepsy Type 1. Neurology. 2022-04-07. PMID:35387850. |
narcolepsy type 1 is a central disorder of hypersomnolence characterized by excessive daytime sleepiness, cataplexy (i.e., sudden loss of muscle tone during wakefulness triggered by emotions), and rapid eye movement sleep-related manifestations that can present with a peculiar phenotype when arising at a pediatric age. |
2022-04-07 |
2023-08-13 |
Not clear |
Shi Zhou, Akira Yamashita, Jingyang Su, Yang Zhang, Wuyang Wang, Liying Hao, Akihiro Yamanaka, Tomoyuki Kuwak. Activity of putative orexin neurons during cataplexy. Molecular brain. vol 15. issue 1. 2022-03-05. PMID:35246205. |
the absence of cataplexy in wild-type mice may be explained by basal or residual activity-induced orexin release, and emotional stimulus-induced counter activation of orexin neurons may not be necessary. |
2022-03-05 |
2023-08-13 |
mouse |
Logan Schneider, Jeffrey Ellenboge. Images: Facial cataplexy with demonstration of persistent eye movements. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 16. issue 1. 2021-06-23. PMID:31957646. |
cataplexy recapitulates this pattern, and is often induced by extreme emotions, laughter in this case. |
2021-06-23 |
2023-08-13 |
Not clear |
Logan Schneider, Jeffrey Ellenboge. Images: Facial cataplexy with demonstration of persistent eye movements. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 16. issue 1. 2021-06-23. PMID:31957646. |
the diagnosis of cataplexy is often missed, due to clinicians being unfamiliar with the findings and the lack of ability to induce sufficient emotional responses to trigger an episode. |
2021-06-23 |
2023-08-13 |
Not clear |
Laury Quaedackers, Jan De Wit, Sigrid Pillen, Merel Van Gilst, Nikolaos Batalas, Gert Jan Lammers, Panos Markopoulos, Sebastiaan Overee. A Mobile App for Longterm Monitoring of Narcolepsy Symptoms: Design, Development, and Evaluation. JMIR mHealth and uHealth. vol 8. issue 1. 2021-04-01. PMID:31909723. |
although narcolepsy is primarily characterized by excessive daytime sleepiness and cataplexy (loss of muscle control triggered by emotions), patients may suffer from hypnagogic hallucinations, sleep paralysis, and fragmented night sleep. |
2021-04-01 |
2023-08-13 |
Not clear |
Anna A Rogers, Lauren M Aiani, Lou T Blanpain, Sun Yuxian, Renee Moore, Jon T Willi. Deep brain stimulation of hypothalamus for narcolepsy-cataplexy in mice. Brain stimulation. vol 13. issue 5. 2021-03-22. PMID:32320748. |
narcolepsy type 1 (nt1, narcolepsy with cataplexy) is a disabling neurological disorder caused by loss of excitatory orexin neurons from the hypothalamus and is characterized by decreased motivation, sleep-wake fragmentation, intrusion of rapid-eye-movement sleep (rems) during wake, and abrupt loss of muscle tone, called cataplexy, in response to sudden emotions. |
2021-03-22 |
2023-08-13 |
mouse |
Ali Seifinejad, Sha Li, Marie-Laure Possovre, Anne Vassalli, Mehdi Taft. Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy. Nature communications. vol 11. issue 1. 2020-12-10. PMID:33247179. |
loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. |
2020-12-10 |
2023-08-13 |
mouse |
Sakh Khalsa, Kasim Qureshi, Andrew P Bagshaw, Amir Rathe. Late Diagnosis of Narcolepsy With Cataplexy: A Novel Case of Cataplectic Facies Presenting in an Elderly Woman. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 15. issue 11. 2020-12-09. PMID:31739861. |
an interesting observation is that the usual emotional triggers associated with cataplexy such as laughter and joking are not always present, thus hampering diagnosis of the underlying syndrome. |
2020-12-09 |
2023-08-13 |
Not clear |
Catherine A McCall, Nathaniel F Watso. Therapeutic Strategies for Mitigating Driving Risk in Patients with Narcolepsy. Therapeutics and clinical risk management. vol 16. 2020-11-20. PMID:33209031. |
narcolepsy is a central nervous system hypersomnia disorder characterized by uncontrollable episodes of daytime sleep, sleep state instability, and cataplexy (sudden loss of muscle tone precipitated by emotion). |
2020-11-20 |
2023-08-13 |
Not clear |