| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jesse T Kaye, Jennifer M Betts, Elana Brubaker, Kirsten Webster, Jean C Beckham, Timothy B Baker, Jessica W Coo. Behavioral activation for smoking cessation in veterans with posttraumatic stress disorder: A randomized clinical trial. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2025-03-12. PMID:40071390. |
behavioral activation (ba) targets anhedonia (i.e., reward insensitivity), which is linked with difficulties in quitting smoking and that is especially common and severe amongst mental health populations, including those with posttraumatic stress disorder (ptsd). |
2025-03-12 |
2025-03-14 |
Not clear |
| Avijit Chowdhury, Sarah Boukezzi, Sara Costi, Sara Hameed, Yael Jacob, Ramiro Salas, Dan V Iosifescu, Ming-Hu Han, Alan Swann, Sanjay J Mathew, Laurel Morris, James W Murroug. Effects of the KCNQ (Kv7) Channel Opener Ezogabine on Resting-State Functional Connectivity of Striatal Brain Reward Regions, Depression and Anhedonia in Major Depressive Disorder: Results from a Randomized Controlled Trial. Biological psychiatry. 2025-03-06. PMID:40049579. |
effects of the kcnq (kv7) channel opener ezogabine on resting-state functional connectivity of striatal brain reward regions, depression and anhedonia in major depressive disorder: results from a randomized controlled trial. |
2025-03-06 |
2025-03-09 |
Not clear |
| Avijit Chowdhury, Sarah Boukezzi, Sara Costi, Sara Hameed, Yael Jacob, Ramiro Salas, Dan V Iosifescu, Ming-Hu Han, Alan Swann, Sanjay J Mathew, Laurel Morris, James W Murroug. Effects of the KCNQ (Kv7) Channel Opener Ezogabine on Resting-State Functional Connectivity of Striatal Brain Reward Regions, Depression and Anhedonia in Major Depressive Disorder: Results from a Randomized Controlled Trial. Biological psychiatry. 2025-03-06. PMID:40049579. |
this study investigates the potential of the potassium kcnq (kv7) channel opener ezogabine to modulate the resting-state functional connectivity (rsfc) of the brain's reward circuitry and alleviate depressive symptoms, including anhedonia, a core feature of mdd. |
2025-03-06 |
2025-03-09 |
Not clear |
| Aditya Singh, Mandakh Bekhbat, David R Goldsmith, Ngoc-Anh Le, Evanthia C Wommack, Zhihao Li, Ebrahim Haroon, Jennifer C Felge. Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression. Comprehensive psychoneuroendocrinology. vol 21. 2025-02-21. PMID:39981264. |
lipids and c-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression. |
2025-02-21 |
2025-02-23 |
Not clear |
| Aditya Singh, Mandakh Bekhbat, David R Goldsmith, Ngoc-Anh Le, Evanthia C Wommack, Zhihao Li, Ebrahim Haroon, Jennifer C Felge. Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression. Comprehensive psychoneuroendocrinology. vol 21. 2025-02-21. PMID:39981264. |
to extend our previous findings on relationships between plasma lipids and antidepressant response to anti-cytokine therapy, we explored in secondary analyses whether lipid-related biomarkers similarly predicted change in anhedonia or functional connectivity (fc) in dopamine-rich corticostriatal reward circuitry in medically-stable, depressed patients with a range of inflammation levels (indexed by plasma c-reactive protein [crp]) who were administered inflammation-targeted therapies. |
2025-02-21 |
2025-02-23 |
Not clear |
| Anna Daniels, Sarah A Wellan, Anne Beck, Susanne Erk, Carolin Wackerhagen, Nina Romanczuk-Seiferth, Kristina Schwarz, Janina I Schweiger, Andreas Meyer-Lindenberg, Andreas Heinz, Henrik Walte. Anhedonia relates to reduced striatal reward anticipation in depression but not in schizophrenia or bipolar disorder: A transdiagnostic study. Cognitive, affective & behavioral neuroscience. 2025-01-30. PMID:39885092. |
anhedonia, i.e., the loss of pleasure or lack of reactivity to reward, is a core symptom of major psychiatric conditions. |
2025-01-30 |
2025-02-02 |
human |
| Anna Daniels, Sarah A Wellan, Anne Beck, Susanne Erk, Carolin Wackerhagen, Nina Romanczuk-Seiferth, Kristina Schwarz, Janina I Schweiger, Andreas Meyer-Lindenberg, Andreas Heinz, Henrik Walte. Anhedonia relates to reduced striatal reward anticipation in depression but not in schizophrenia or bipolar disorder: A transdiagnostic study. Cognitive, affective & behavioral neuroscience. 2025-01-30. PMID:39885092. |
altered reward processing in the striatum has been observed across mood and psychotic disorders, but whether anhedonia transdiagnostically contributes to these deficits remains unclear. |
2025-01-30 |
2025-02-02 |
human |
| Chenlu Guan, Shiyu Zhou, Zhao Wang, Bo Gao, Ya Zhen. Greater neural delay discounting on reward evaluation in anhedonia. International journal of clinical and health psychology : IJCHP. vol 25. issue 1. 2025-01-29. PMID:39877890. |
greater neural delay discounting on reward evaluation in anhedonia. |
2025-01-29 |
2025-01-31 |
Not clear |
| Chenlu Guan, Shiyu Zhou, Zhao Wang, Bo Gao, Ya Zhen. Greater neural delay discounting on reward evaluation in anhedonia. International journal of clinical and health psychology : IJCHP. vol 25. issue 1. 2025-01-29. PMID:39877890. |
however, few research has directly examined reward valuation as a function of time in anhedonia. |
2025-01-29 |
2025-01-31 |
Not clear |
| Masashi Koda, Hiroyuki Kawai, Hisashi Shirakawa, Shuji Kaneko, Kazuki Nagayas. Effect of antidepressants and social defeat stress on the activity of dorsal raphe serotonin neurons in free-moving animals. Journal of pharmacological sciences. vol 157. issue 2. 2025-01-19. PMID:39828391. |
major depressive disorder (mdd) is among the most common mental disorders worldwide and is characterized by dysregulated reward processing associated with anhedonia. |
2025-01-19 |
2025-01-23 |
mouse |
| Eleonora Corridori, Sara Salviati, Veronica Begni, Alessia Marchesin, Carla Gambarana, Marco Andrea Riva, Simona Schegg. Restorative properties of chronic lurasidone treatment on emotional dysfunction in rats exposed to chronic unavoidable stress: a role for medial prefrontal cortex - nucleus accumbens network. Neuropharmacology. 2025-01-15. PMID:39814132. |
in this study, we aimed to investigate the pro-motivational properties of lurasidone in a rat (sprague dawley males) model of anhedonia and to unravel the interplay between lurasidone and the brain regions critical for reward processing. |
2025-01-15 |
2025-01-19 |
rat |
| Yajing Xu, Shan Yang, Cong Ca. Glucocorticoid Receptor Gene (NR3C1) Methylation Childhood Maltreatment Multilevel Reward Responsiveness and Depressive and Anxiety Symptoms: A Neuroimaging Epigenetic Study. NeuroImage. 2025-01-08. PMID:39778819. |
we conducted the first longitudinal study to investigate the extent to which dna methylation of a stress-related gene-nr3c1-interacts with childhood maltreatment in association with young adult reward responsiveness (rr) and the downstream risk of depressive (anhedonia dimension in particular) and anxiety symptoms. |
2025-01-08 |
2025-01-13 |
Not clear |
| Isaac D Romkey, Tomas Matthews, Nicholas Foster, Simone Dalla Bella, Virginia B Penhun. The pleasurable urge to move to music is unchanged in people with musical anhedonia. PloS one. vol 20. issue 1. 2025-01-08. PMID:39774498. |
people with musical anhedonia were identified as those with scores in the lower 10% of scores on the barcelona musical reward questionnaire, but who had no deficits in music perception, no symptoms of depression, average levels of physical and social anhedonia, and sensitivity to punishment and reward. |
2025-01-08 |
2025-01-13 |
Not clear |
| Laetitia Imbert, Cécilia Neige, Maylis Dumas, Moustafa Bensafi, Nathalie Mandairon, Jérôme Bruneli. Combining pleasant Olfactory and BRAin stimulations in treatment-resistant depression (COBRA): study protocol for a randomized controlled trial. Frontiers in psychology. vol 15. 2025-01-02. PMID:39744036. |
at the neurobiological level, anhedonia has been associated with abnormal activity within the reward system, suggesting a key role for dopamine. |
2025-01-02 |
2025-01-04 |
Not clear |
| Bekhbat Mandakh, Li Zhihao, Boadie W Dunlop, Michael T Treadway, Neeti D Mehta, Kate P Revill, Michael J Lucido, Hong Changdo, Ashchi Andrea, Evanthia C Wommack, David R Goldsmith, Haroon Ebrahim, Andrew H Miller, Jennifer C Felge. Sustained effects of repeated levodopa (L-DOPA) administration on reward circuitry, effort-based motivation, and anhedonia in depressed patients with higher inflammation. Brain, behavior, and immunity. 2024-12-18. PMID:39694342. |
sustained effects of repeated levodopa (l-dopa) administration on reward circuitry, effort-based motivation, and anhedonia in depressed patients with higher inflammation. |
2024-12-18 |
2024-12-21 |
Not clear |
| Bekhbat Mandakh, Li Zhihao, Boadie W Dunlop, Michael T Treadway, Neeti D Mehta, Kate P Revill, Michael J Lucido, Hong Changdo, Ashchi Andrea, Evanthia C Wommack, David R Goldsmith, Haroon Ebrahim, Andrew H Miller, Jennifer C Felge. Sustained effects of repeated levodopa (L-DOPA) administration on reward circuitry, effort-based motivation, and anhedonia in depressed patients with higher inflammation. Brain, behavior, and immunity. 2024-12-18. PMID:39694342. |
inflammatory biomarkers like c-reactive protein (crp) are elevated in a subset of patients with depression and associated with lower functional connectivity (fc) in a ventral striatum (vs) to ventromedial prefrontal cortex (vmpfc) reward circuit and symptoms of anhedonia. |
2024-12-18 |
2024-12-21 |
Not clear |
| Stefanie L Sequeira, Julianne M Griffith, T H Stanley Seah, Kiera M James, Cecile D Ladouceur, Jennifer S Sil. Real-World Social Reward Processes are Linked to Momentary Positive Affect in Adolescent Girls. Research on child and adolescent psychopathology. 2024-12-12. PMID:39666125. |
showing little interest in interacting socially with peers and/or extracting little reward from positive peer interactions can be markers of social anhedonia, which impacts many youths, especially girls, with social anxiety and depressive disorders. |
2024-12-12 |
2024-12-14 |
Not clear |
| Stefanie L Sequeira, Julianne M Griffith, T H Stanley Seah, Kiera M James, Cecile D Ladouceur, Jennifer S Sil. Real-World Social Reward Processes are Linked to Momentary Positive Affect in Adolescent Girls. Research on child and adolescent psychopathology. 2024-12-12. PMID:39666125. |
reduced interest or reward in peer interactions may contribute to social anxiety and depression in girls through effects on positive affect (pa), though associations between social anhedonia and momentary pa have yet to be tested. |
2024-12-12 |
2024-12-14 |
Not clear |
| Arzoo Pannu, Ramesh K Goya. The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects. CNS & neurological disorders drug targets. 2024-12-06. PMID:39639477. |
the mlp, which is key to reward processing, is linked to anhedonia, a primary depression symptom. |
2024-12-06 |
2024-12-08 |
Not clear |
| C E Parsons, L Tollånes, M Cella, C R Hirsch, K S Youn. Translational assessment of anhedonia components: Significant associations between reward anticipation measured via behavioural task performance, daily smartphone reports, and general anhedonia questionnaires. Behaviour research and therapy. vol 184. 2024-12-01. PMID:39616661. |
we examine anhedonia components, combining experimental training, with multimodal anhedonia assessment, comprising standard questionnaire instruments, a widely-used behavioural task, and daily reports of reward experience. |
2024-12-01 |
2024-12-06 |
Not clear |