| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiayang Xiao, Joshua A Adkinson, John Myers, Anusha B Allawala, Raissa K Mathura, Victoria Pirtle, Ricardo Najera, Nicole R Provenza, Eleonora Bartoli, Andrew J Watrous, Denise Oswalt, Ron Gadot, Adrish Anand, Ben Shofty, Sanjay J Mathew, Wayne K Goodman, Nader Pouratian, Xaq Pitkow, Kelly R Bijanki, Benjamin Hayden, Sameer A Shet. Beta activity in human anterior cingulate cortex mediates reward biases. Nature communications. vol 15. issue 1. 2024-07-15. PMID:39009561. |
our findings suggest that acc beta oscillations may orchestrate the learning of reward information to guide adaptive choice, and, more broadly, suggest a potential biomarker for anhedonia and point to future development of interventions to enhance reward impact for therapeutic benefit. |
2024-07-15 |
2024-07-18 |
human |
| Koen Demyttenaer. Aticaprant, a kappa opioid receptor antagonist, and the recovered 'interest and pleasure' in the concept of major depressive disorder. European archives of psychiatry and clinical neuroscience. 2024-07-05. PMID:38969753. |
anhedonia is a multifaceted concept: the clinical language describes anticipatory/consummatory anhedonia and sensory/social anhedonia while the cognitive neuroscience language describes readiness for reward, energy expenditure to attain reward, updating reward presence and value. |
2024-07-05 |
2024-07-08 |
Not clear |
| E J Hird, A Slanina-Davies, G Lewis, M Hamer, J P Roise. From movement to motivation: a proposed framework to understand the antidepressant effect of exercise. Translational psychiatry. vol 14. issue 1. 2024-07-03. PMID:38961071. |
drawing on a broad range of research in humans and animals, we propose that by reducing inflammation and boosting dopamine transmission, with consequent effects on effort-based decision making for reward, exercise initially specifically improves 'interest-activity' symptoms of depression-namely anhedonia, fatigue and subjective cognitive impairment - by increasing propensity to exert effort. |
2024-07-03 |
2024-07-08 |
Not clear |
| Minjee Jung, Kyu-Man Ha. Behavioral Activation and Brain Network Changes in Depression. Journal of clinical neurology (Seoul, Korea). vol 20. issue 4. 2024-07-02. PMID:38951971. |
there are clear links between the neural mechanisms underlying reward processing and ba treatment for depressive symptoms, including anhedonia; however, integrated interpretations of these two domains are lacking. |
2024-07-02 |
2024-07-04 |
Not clear |
| Paloma Martinez Gonzalez, Amaya R Jenkins, Kayleigh S LaMalfa, Brian D Kanga. Chronic ecologically relevant stress effects on reverse-translated touchscreen assays of reward responsivity and attentional processes in male rats: Implications for depression. Journal of neurochemistry. 2024-06-26. PMID:38922872. |
these tasks previously have been reverse-translated using touchscreen technology for rodents and nonhuman primates to objectively quantify, respectively, reward responsivity (anhedonia) and attentional processes (impaired cognitive function), each of which are core features of major depressive disorder. |
2024-06-26 |
2024-06-29 |
human |
| Liliana Patarroyo-Rodriguez, Stefanie Cavalcanti, Jennifer L Vande Voort, Balwinder Sing. The Use of Ketamine for the Treatment of Anhedonia in Depression. CNS drugs. 2024-06-23. PMID:38910222. |
anhedonia, a complex symptom rooted in deficits across reward processes, is primarily linked to depression and schizophrenia but transcends diagnostic boundaries across various mental disorders. |
2024-06-23 |
2024-06-26 |
Not clear |
| Shakila Meshkat, Angela T H Kwan, Gia Han Le, Sabrina Wong, Taeho Greg Rhee, Roger Ho, Kayla M Teopiz, Bing Cao, Roger S McIntyr. The role of KCNQ channel activators in management of major depressive disorder. Journal of affective disorders. 2024-05-21. PMID:38772507. |
recent preclinical evidence suggests that kcnq channels, particularly kcnq3, contribute to the regulation of neuronal excitability within the reward circuitry, offering a potential target for alleviating depressive symptoms, notably anhedonia. |
2024-05-21 |
2024-05-27 |
human |
| Hailing Wen, Menglin Wu, Zhao Wang, Bo Gao, Ya Zhen. Aberrant effort-based reward dynamics in anhedonia. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 5. 2024-05-14. PMID:38741268. |
aberrant effort-based reward dynamics in anhedonia. |
2024-05-14 |
2024-05-27 |
Not clear |
| Hailing Wen, Menglin Wu, Zhao Wang, Bo Gao, Ya Zhen. Aberrant effort-based reward dynamics in anhedonia. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 5. 2024-05-14. PMID:38741268. |
anhedonia is a transdiagnostic symptom and associated with a spectrum of reward deficits among which the motivational dysfunction is poorly understood. |
2024-05-14 |
2024-05-27 |
Not clear |
| Hailing Wen, Menglin Wu, Zhao Wang, Bo Gao, Ya Zhen. Aberrant effort-based reward dynamics in anhedonia. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 5. 2024-05-14. PMID:38741268. |
our findings suggest that anhedonia is associated with an inefficient control and motivation allocation along the efforted-based reward dynamics from effort preparation to effort production. |
2024-05-14 |
2024-05-27 |
Not clear |
| Magdalena Ferstl, Anne Kühnel, Johannes Klaus, Wy Ming Lin, Nils B Kroeme. Non-invasive vagus nerve stimulation conditions increased invigoration and wanting in depression. Comprehensive psychiatry. vol 132. 2024-04-24. PMID:38657358. |
major depressive disorder (mdd) is often marked by impaired motivation and reward processing, known as anhedonia. |
2024-04-24 |
2024-04-28 |
human |
| Min Gao, Megan Kirk, Eva Lash, Heather Knight, Moscho Michalopoulou, Nicola Guess, Michael Browning, Scott Weich, Philip Burnet, Susan A Jebb, Richard Stevens, Paul Aveyar. Evaluating the efficacy and mechanisms of a ketogenic diet as adjunctive treatment for people with treatment-resistant depression: A protocol for a randomised controlled trial. Journal of psychiatric research. vol 174. 2024-04-23. PMID:38653031. |
some case reports suggest that ketogenic diets (kds) may improve some mental illnesses, and preclinical data indicate that kds can influence brain reward signalling, anhedonia, cortisol, and gut microbiome which are associated with depression. |
2024-04-23 |
2024-04-26 |
Not clear |
| Filippo Queirazza, Jonathan Cavanagh, Marios G Philiastides, Rajeev Krishnada. Mild exogenous inflammation blunts neural signatures of bounded evidence accumulation and reward prediction error processing in healthy male participants. Brain, behavior, and immunity. 2024-03-31. PMID:38555987. |
so far, it has been reported that blunted mesolimbic dopamine reward signals are associated with inflammation-induced anhedonia and apathy. |
2024-03-31 |
2024-04-03 |
human |
| Sonia Sistiaga, Wan-Ling Tseng, Lanting Zhang, Mandy Rossignol, Nellia Bellaer. How are irritability and anhedonia symptoms linked? A network approach. Journal of clinical psychology. 2024-03-18. PMID:38497904. |
anhedonia is a multifaceted symptom reflecting impairments in multiple dimensions of reward processing (e.g., pleasure, desire, motivation, and effort) across distinct reward types (e.g., food, sensory experiences, social activities, hobbies) that may differentially interact with irritability. |
2024-03-18 |
2024-03-20 |
Not clear |
| Aaron S Helle. Adding to the neuroimmune network model: A commentary on Nusslock et al. (2024). Journal of child psychology and psychiatry, and allied disciplines. 2024-03-16. PMID:38491727. |
second, the authors suggest that reward circuits, including the striatum, may be targets of increased inflammation leading to symptoms of anhedonia. |
2024-03-16 |
2024-03-19 |
Not clear |
| Amanda E Guye. Understanding the paradox: anhedonia and the unexpected divergence from reward seeking during adolescence - A commentary on Gupta et al. (2024). Journal of child psychology and psychiatry, and allied disciplines. 2024-03-16. PMID:38491724. |
understanding the paradox: anhedonia and the unexpected divergence from reward seeking during adolescence - a commentary on gupta et al. |
2024-03-16 |
2024-03-19 |
Not clear |
| Rotem Dan, Alexis E Whitton, Michael T Treadway, Ashleigh V Rutherford, Poornima Kumar, Manon L Ironside, Roselinde H Kaiser, Boyu Ren, Diego A Pizzagall. Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-14. PMID:38480910. |
taken together, across dsm mood diagnoses, efficiency and centrality of the reward circuit predicted symptoms of anhedonia, impulsivity, and (hypo)mania, cross-sectionally and prospectively. |
2024-03-14 |
2024-03-16 |
human |
| Anna F Hall, Michael Browning, Quentin J M Huy. The computational structure of consummatory anhedonia. Trends in cognitive sciences. 2024-02-29. PMID:38423829. |
the enjoyment aspect, termed 'consummatory anhedonia', in particular poses fundamental questions about how the brain constructs rewards: what processes determine how intensely a reward is experienced? |
2024-02-29 |
2024-03-03 |
Not clear |
| Tina Gupta, Kristen L Eckstrand, Erika E Forbe. Annual Research Review: Puberty and the development of anhedonia - considering childhood adversity and inflammation. Journal of child psychology and psychiatry, and allied disciplines. 2024-02-23. PMID:38391011. |
this review takes a developmental perspective, considering the possibility that anhedonia emerges in the context of pubertal maturation and adolescent development, with childhood adversity and chronic inflammation influencing neural reward systems to accelerate anhedonia's progression. |
2024-02-23 |
2024-02-25 |
Not clear |
| Emillie Beyer, Govinda Poudel, Stephanie Antonopoulos, Hannah Thomson, Valentina Lorenzett. Brain reward function in people who use cannabis: a systematic review. Frontiers in behavioral neuroscience. vol 17. 2024-02-21. PMID:38379938. |
cannabis use can be associated with alterations of reward processing, including affective flattening, apathy, anhedonia, and lower sensitivity to natural rewards in conjunction with higher sensitivity to cannabis-related rewards. |
2024-02-21 |
2024-02-23 |
Not clear |