| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Chan, S J Crutch, E K Warringto. A disorder of colour perception associated with abnormal colour after-images: a defect of the primary visual cortex. Journal of neurology, neurosurgery, and psychiatry. vol 71. issue 4. 2001-12-04. PMID:11561036. |
this may occur as a consequence of the relative sparing of inhibitory interneurons in v1 in the context of the degeneration of excitatory neurons that occurs in alzheimer's disease. |
2001-12-04 |
2023-08-12 |
Not clear |
| G Leuba, K Saini, V Zimmermann, P Giannakopoulos, C Boura. Mild amyloid pathology in the primary visual system of nonagenarians and centenarians. Dementia and geriatric cognitive disorders. vol 12. issue 2. 2001-07-12. PMID:11173888. |
in order to study the patterns of alzheimer disease (ad)-related pathology in the primary visual system of the oldest old, we performed a quantitative analysis of senile plaques (sp), diffuse beta amyloid (a beta) deposit and neurofibrillary tangle (nft) distribution in primary area 17, and a semi-quantitative analysis in the dorsal lateral geniculate nucleus (lgn), lateral inferior pulvinar (lip) and superior colliculus (sc) of 21 individuals aged between 93 and 102 years. |
2001-07-12 |
2023-08-12 |
Not clear |
| E M Reiman, A Uecker, F Gonzalez-Lima, D Minear, K Chen, N L Callaway, J D Berndt, D Game. Tracking Alzheimer's disease in transgenic mice using fluorodeoxyglucose autoradiography. Neuroreport. vol 11. issue 5. 2000-07-10. PMID:10790869. |
using fluorodeoxyglucose (fdg) autoradiography, we found that transgenic mice over-expressing a mutant form of the human amyloid precursor protein have preferentially and progressively reduced activity in the posterior cingulate cortex and relatively spared activity in visual cortex, sensorimotor cortex, cerebellum and brain stem, a pattern previously demonstrated in fdg pet studies of persons with alzheimer's disease, brain imaging of posterior cingulate activity could provide an indicator of ad in suitable animals, helping to clarify disease mechanisms and screen candidate treatments. |
2000-07-10 |
2023-08-12 |
mouse |
| D T Yew, W P Li, S E Webb, H W Lai, L Zhan. Neurotransmitters, peptides, and neural cell adhesion molecules in the cortices of normal elderly humans and Alzheimer patients: a comparison. Experimental gerontology. vol 34. issue 1. 1999-05-27. PMID:10197733. |
immunocytochemical techniques was used to compare the proportion of neurons expressing various neurotransmitters (tyrosine hydroxylase, choline acetyltransferase and gamma-aminobutyric acid), neuropeptides (leu-enkephalin and substance p) and neural cell adhesion molecules (ncam) in the hippocampus, frontal (area 10) and occipital (area 17) cortices of neurologically normal elderly humans to that of age-matched alzheimer disease (ad) patients. |
1999-05-27 |
2023-08-12 |
Not clear |
| G Leuba, R Kraftsik, K Sain. Quantitative distribution of parvalbumin, calretinin, and calbindin D-28k immunoreactive neurons in the visual cortex of normal and Alzheimer cases. Experimental neurology. vol 152. issue 2. 1998-09-24. PMID:9710527. |
quantitative distribution of parvalbumin, calretinin, and calbindin d-28k immunoreactive neurons in the visual cortex of normal and alzheimer cases. |
1998-09-24 |
2023-08-12 |
Not clear |
| G Leuba, R Kraftsik, K Sain. Quantitative distribution of parvalbumin, calretinin, and calbindin D-28k immunoreactive neurons in the visual cortex of normal and Alzheimer cases. Experimental neurology. vol 152. issue 2. 1998-09-24. PMID:9710527. |
the distribution of parvalbumin (pv), calretinin (cr), and calbindin (cb) immunoreactive neurons was studied with the help of an image analysis system (vidas/zeiss) in the primary visual area 17 and associative area 18 (brodmann) of alzheimer and control brains. |
1998-09-24 |
2023-08-12 |
Not clear |
| G Leuba, R Kraftsik, K Sain. Quantitative distribution of parvalbumin, calretinin, and calbindin D-28k immunoreactive neurons in the visual cortex of normal and Alzheimer cases. Experimental neurology. vol 152. issue 2. 1998-09-24. PMID:9710527. |
our data show that, although the brain pathology is moderate to severe, there is no prominent decrease of pv, cr and cb positive neurons in the visual cortex of alzheimer brains, but only selective changes in neuronal perikarya. |
1998-09-24 |
2023-08-12 |
Not clear |
| R O Kuljis, R K Tiko. Discontinuous distribution of senile plaques within striate cortex hypercolumns in Alzheimer's disease. Vision research. vol 37. issue 24. 1998-02-02. PMID:9425532. |
discontinuous distribution of senile plaques within striate cortex hypercolumns in alzheimer's disease. |
1998-02-02 |
2023-08-12 |
Not clear |
| R O Kuljis, R K Tiko. Discontinuous distribution of senile plaques within striate cortex hypercolumns in Alzheimer's disease. Vision research. vol 37. issue 24. 1998-02-02. PMID:9425532. |
tangential sections of the primary visual (striate) cerebral cortex from five patients with histopathologically verified alzheimer's disease were used to study the laminar and tangential disposition of senile plaques. |
1998-02-02 |
2023-08-12 |
Not clear |
| R O Kuljis, R K Tiko. Discontinuous distribution of senile plaques within striate cortex hypercolumns in Alzheimer's disease. Vision research. vol 37. issue 24. 1998-02-02. PMID:9425532. |
taken together, these findings indicate that: (1) senile plaques may arise in functionally and anatomically distinct subsets of iterated neuronal circuits that cannot be reduced to schemes based on traditional cytoarchitectonic layers; and (2) that individual variability in the patterns of striate cortex involvement and clinical manifestations must be taken into consideration when addressing the specific mechanisms underlying visual dysfunction in alzheimer's disease. |
1998-02-02 |
2023-08-12 |
Not clear |
| R Rodríguez-Puertas, J Pascual, T Vilaró, A Pazo. Autoradiographic distribution of M1, M2, M3, and M4 muscarinic receptor subtypes in Alzheimer's disease. Synapse (New York, N.Y.). vol 26. issue 4. 1997-09-09. PMID:9215593. |
we studied the autoradiographic densities of all pharmacologically characterised muscarinic receptors (mr) in frontal, temporal, and visual cortex, hippocampal formation, and striatum in autopsied brains from 19 histopathologically verified patients of alzheimer's disease (ad) and in matched controls. |
1997-09-09 |
2023-08-12 |
Not clear |
| A L Foundas, C M Leonard, S M Mahoney, O F Agee, K M Heilma. Atrophy of the hippocampus, parietal cortex, and insula in Alzheimer's disease: a volumetric magnetic resonance imaging study. Neuropsychiatry, neuropsychology, and behavioral neurology. vol 10. issue 2. 1997-08-07. PMID:9150507. |
to determine whether the atrophy is limited to certain cortical regions, the striate cortex was measured because this area is not usually neuropathologically involved early in alzheimer's disease. |
1997-08-07 |
2023-08-12 |
Not clear |
| R A Armstron. Visual field defects in Alzheimer's disease patients may reflect differential pathology in the primary visual cortex. Optometry and vision science : official publication of the American Academy of Optometry. vol 73. issue 11. 1997-02-28. PMID:8950748. |
visual field defects in alzheimer's disease patients may reflect differential pathology in the primary visual cortex. |
1997-02-28 |
2023-08-12 |
Not clear |
| R A Armstron. Visual field defects in Alzheimer's disease patients may reflect differential pathology in the primary visual cortex. Optometry and vision science : official publication of the American Academy of Optometry. vol 73. issue 11. 1997-02-28. PMID:8950748. |
the aim of this study was to test the hypothesis that differences in density of senile plaques (sp) and neurofibrillary tangles (nft) in the cuneal and lingual gyri of area v1 of the visual cortex could explain the predominantly inferior visual field defects seen in patients with alzheimer's disease (ad). |
1997-02-28 |
2023-08-12 |
Not clear |
| P J Norris, R L Faull, P C Emso. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883932. |
neuronal nitric oxide synthase (nnos) mrna expression and nadph-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and alzheimer's disease brains. |
1997-02-20 |
2023-08-12 |
human |
| P J Norris, R L Faull, P C Emso. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883932. |
neuronal nitric oxide synthase (nnos) mrna levels and nadph diaphorase (nadph-d) staining were compared in the frontal cortex, visual cortex and hippocampus (dentate gyrus and ca subfields of ammon's horn) of five alzheimer's disease (ad) and six control brains. |
1997-02-20 |
2023-08-12 |
human |
| K Terai, A Matsuo, P L McGee. Enhancement of immunoreactivity for NF-kappa B in the hippocampal formation and cerebral cortex of Alzheimer's disease. Brain research. vol 735. issue 1. 1997-02-11. PMID:8905182. |
the distribution of nuclear factor-kappa b (nf-kappa b) was investigated immunohistochemically in the hippocampal formation, entorhinal cortex, middle temporal gyrus and visual cortex of alzheimer's disease (ad) and control postmortem cases using a polyclonal antibody against the nf-kappa b p65 subunit. |
1997-02-11 |
2023-08-12 |
Not clear |
| G Leuba, K Sain. Pathology of subcortical visual centres in relation to cortical degeneration in Alzheimer's disease. Neuropathology and applied neurobiology. vol 21. issue 5. 1996-07-03. PMID:8632836. |
subcortical visual centres such as the lateral geniculate nucleus, the lateral inferior pulvinar and the superior colliculus, together with the primary visual cortex and its adjacent white matter, were studied in 12 alzheimer brains and five age-matched controls. |
1996-07-03 |
2023-08-12 |
Not clear |
| R Mielke, J Kessler, G Fink, K Herholz, W D Heis. Dysfunction of visual cortex contributes to disturbed processing of visual information in Alzheimer's disease. The International journal of neuroscience. vol 82. issue 1-2. 1995-11-24. PMID:7591506. |
dysfunction of visual cortex contributes to disturbed processing of visual information in alzheimer's disease. |
1995-11-24 |
2023-08-12 |
Not clear |
| L C Ang, D D Shu. Peptidergic neurons of subcortical white matter in aging and Alzheimer's brain. Brain research. vol 674. issue 2. 1995-08-03. PMID:7540926. |
the peptidergic neurons in the subcortical white matter, beneath the striate cortex were examined qualitatively and qualitatively with immunohistochemistry for substance p, cholecystokinin, somatostatin and neuropeptide y in seven control patients and eight patients with alzheimer's disease. |
1995-08-03 |
2023-08-12 |
Not clear |