| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fabio Casciano, Enrico Zauli, Claudio Celeghini, Lorenzo Caruso, Arianna Gonelli, Giorgio Zauli, Angela Pignatell. Retinal Alterations Predict Early Prodromal Signs of Neurodegenerative Disease. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338966. |
similarly, the visual cortex is modified by the neurofibrillary tangles and neuritic amyloid β plaques typically seen in the alzheimer's disease brain, and this may reflect the accumulation of these biomarkers in the retina during the early stages of the disease, as seen in postmortem retinas of ad patients. |
2024-02-10 |
2024-02-12 |
Not clear |
| Irene Navarro-Lobato, Mariam Masmudi-Martín, Manuel F López-Aranda, Juan F López-Téllez, Gloria Delgado, Pablo Granados-Durán, Celia Gaona-Romero, Marta Carretero-Rey, Sinforiano Posadas, María E Quiros-Ortega, Zafar U Kha. Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103251. |
promotion of structural plasticity in area v2 of visual cortex prevents against object recognition memory deficits in aging and alzheimer's disease rodents. |
2023-12-16 |
2023-12-19 |
mouse |
| Oliver J L'Esperance, Josh McGhee, Garett Davidson, Adam Steven Smith, Jaichandar Subramania. Functional connectivity favors hyperactivity leading to synapse loss in amyloidosis. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36712054. |
hyperactivity is observed in early alzheimer's disease (ad) in multiple brain regions, including the visual cortex. |
2023-01-30 |
2023-08-14 |
mouse |
| Maurizio Gallucci, Vittorio Fiore, Francesca Grassivaro, Chiara Da Ronch, Laura Bonann. "Occipital Pole" Sign on 18F-FDG PET for Dementia With Lewy Bodies and Posterior Cortical Atrophy: Evidence From the Treviso Dementia (TREDEM) Registry. Clinical nuclear medicine. 2022-04-27. PMID:35473924. |
the 18f-fdg pet images of dementia with lewy bodies and posterior cortical atrophy, a visual-cognitive phenotype described in patients with alzheimer disease, show occipital lobe hypometabolism with relative sparing of the primary visual cortex (pvc) generating the "occipital tunnel" sign proposed by sawyer and kuo in 2017, which is viewable on the medial sagittal projection. |
2022-04-27 |
2023-08-13 |
Not clear |
| Younes Adam Tabi, Maria Raquel Maio, Bahaaeddin Attaallah, Shannon Dickson, Daniel Drew, Mohamad Imran Idris, Annika Kienast, Verena Klar, Lisa Nobis, Olivia Plant, Youssuf Saleh, Timothy Ravinder Sandhu, Ellie Slavkova, Sofia Toniolo, Nahid Zokaei, Sanjay G Manohar, Masud Husai. Vividness of visual imagery questionnaire scores and their relationship to visual short-term memory performance. Cortex; a journal devoted to the study of the nervous system and behavior. vol 146. 2021-12-11. PMID:34894605. |
here we examined the relationship of visual imagery to stm and hippocampal and primary visual cortex volumes, first in a large sample of healthy people across a large age range (n = 229 behavioural data; n = 56 mri data in older participants) and then in patients with alzheimer's disease and parkinson's disease (n = 19 in each group compared to 19 age-matched healthy controls). |
2021-12-11 |
2023-08-13 |
human |
| Younes Adam Tabi, Maria Raquel Maio, Bahaaeddin Attaallah, Shannon Dickson, Daniel Drew, Mohamad Imran Idris, Annika Kienast, Verena Klar, Lisa Nobis, Olivia Plant, Youssuf Saleh, Timothy Ravinder Sandhu, Ellie Slavkova, Sofia Toniolo, Nahid Zokaei, Sanjay G Manohar, Masud Husai. Vividness of visual imagery questionnaire scores and their relationship to visual short-term memory performance. Cortex; a journal devoted to the study of the nervous system and behavior. vol 146. 2021-12-11. PMID:34894605. |
in conclusion, visual imagery was not significantly related to visual stm performance, either in healthy controls or alzheimer's or parkinson's disease but it was related to hippocampal and visual cortex volume in healthy people. |
2021-12-11 |
2023-08-13 |
human |
| Amy F T Arnsten, Dibyadeep Datta, Min Wan. The genie in the bottle-magnified calcium signaling in dorsolateral prefrontal cortex. Molecular psychiatry. vol 26. issue 8. 2021-10-30. PMID:33319854. |
neurons in the association cortices are particularly vulnerable in cognitive disorders such as schizophrenia and alzheimer's disease, while those in primary visual cortex remain relatively resilient. |
2021-10-30 |
2023-08-13 |
Not clear |
| Eduardo Rosales Jubal, Miriam Schwalm, Malena Dos Santos Guilherme, Florian Schuck, Sven Reinhardt, Amanda Tose, Zeke Barger, Mona K Roesler, Nicolas Ruffini, Anna Wierczeiko, Michael J Schmeisser, Ulrich Schmitt, Kristina Endres, Albrecht Stro. Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer's disease. Scientific reports. vol 11. issue 1. 2021-10-21. PMID:33758244. |
using two-photon calcium imaging, we found altered temporal distributions (burstiness) in the spontaneous activity of layer ii/iii visual cortex neurons, in a mouse model of familial alzheimer's disease (5xfad), before plaque formation. |
2021-10-21 |
2023-08-13 |
mouse |
| Jie Huang, Paul Beach, Andrea Bozoki, David C Zh. Alzheimer's Disease Progressively Reduces Visual Functional Network Connectivity. Journal of Alzheimer's disease reports. vol 5. issue 1. 2021-09-14. PMID:34514338. |
postmortem studies of brains with alzheimer's disease (ad) not only find amyloid-beta (aβ) and neurofibrillary tangles (nft) in the visual cortex, but also reveal temporally sequential changes in ad pathology from higher-order association areas to lower-order areas and then primary visual area (v1) with disease progression. |
2021-09-14 |
2023-08-13 |
Not clear |
| Lília Jorge, Nádia Canário, Ricardo Martins, Beatriz Santiago, Isabel Santana, Hugo Quental, Francisco Ambrósio, Rui Bernardes, Miguel Castelo-Branc. The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid Neural plasticity. vol 2020. 2021-09-13. PMID:33014034. |
the retinal inner plexiform synaptic layer mirrors grey matter thickness of primary visual cortex with increased amyloid the retina may serve as putative window into neuropathology of synaptic loss in alzheimer's disease (ad). |
2021-09-13 |
2023-08-13 |
Not clear |
| Jie Huang, Paul Beach, Andrea Bozoki, David C Zh. Alzheimer's Disease Progressively Alters the Face-Evoked Visual-Processing Network. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32804125. |
postmortem studies of alzheimer's disease (ad) brains not only find amyloid-β (aβ) and neurofibrillary tangles (nft) in the primary and associative visual cortical areas, but also reveal a temporally successive sequence of ad pathology beginning in higher-order visual association areas, followed by involvement of lower-order visual processing regions with disease progression, and extending to primary visual cortex in late-stage disease. |
2021-09-09 |
2023-08-13 |
Not clear |
| Benjamin Chun-Kit Tong, Aston Jiaxi Wu, Alexis Shiying Huang, Rui Dong, Sandeep Malampati, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Sravan Gopalkrishnashetty Sreenivasmurthy, Zhou Zhu, Chengfu Su, Jia Liu, Juxian Song, Jia-Hong Lu, Jieqiong Tan, Weidong Pan, Min Li, King-Ho Cheun. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease. Autophagy. 2021-07-27. PMID:34313551. |
aβ: β-amyloid; ad: alzheimer disease; aif1/iba1: allograft inflammatory factor 1; alp: autophagy-lysosomal pathway; app: amyloid beta precursor protein; atp6v1b1/v-atpase v1b1: atpase h+ transporting v1 subunit b1; avs: autophagy vacuoles; baf: bafilomycin a |
2021-07-27 |
2023-08-13 |
Not clear |
| Huan Cui, Si Su, Yan Cao, Chao Ma, Wenying Qi. The Altered Anatomical Distribution of ACE2 in the Brain With Alzheimer's Disease Pathology. Frontiers in cell and developmental biology. vol 9. 2021-07-13. PMID:34249938. |
in addition, this study demonstrates that the protein level of ace2 was downregulated in the basal nucleus, hippocampus and entorhinal cortex, middle frontal gyrus, visual cortex, and amygdala of the brain with alzheimer's disease (ad) pathology. |
2021-07-13 |
2023-08-13 |
human |
| M S Bobola, L Chen, C K Ezeokeke, T A Olmstead, C Nguyen, A Sahota, R G Williams, P D Moura. Transcranial focused ultrasound, pulsed at 40 Hz, activates microglia acutely and reduces Aβ load chronically, as demonstrated in vivo. Brain stimulation. vol 13. issue 4. 2020-12-04. PMID:32388044. |
(2016) [1] exposed 1 h of light flickering at 40 hz to awake 5xfad alzheimer's disease (ad) mouse models, generating action potentials at 40 hz, activating ∼54% of microglia to colocalize with aβ plaque, acutely, and clearing ∼ 50% of aβ plaque after seven days, but only in the visual cortex. |
2020-12-04 |
2023-08-13 |
mouse |
| Michael A Meyer, Stephen A Hudoc. Posterior cortical atrophy: A rare variant of Alzheimer's disease. Neurology international. vol 10. issue 2. 2020-10-01. PMID:30069290. |
this rare combination of findings in association with her dementia led to a detailed review of all her imaging studies, concluding with the surprising recognition for a clear hemi-atrophy of the primary left occipital cortex was occurring, consistent with alzheimer's disease affecting the primary visual cortex. |
2020-10-01 |
2023-08-13 |
Not clear |
| Michael A Meyer, Stephen A Hudoc. Posterior cortical atrophy: A rare variant of Alzheimer's disease. Neurology international. vol 10. issue 2. 2020-10-01. PMID:30069290. |
further awareness of this disease pattern is needed, as alzheimer's disease typically does not affect the primary visual cortex; other conditions to consider in general include lewy body dementia, cortico-basal degeneration and prion disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Elena Salobrar-García, Rosa de Hoz, Ana I Ramírez, Inés López-Cuenca, Pilar Rojas, Ravi Vazirani, Carla Amarante, Raquel Yubero, Pedro Gil, María D Pinazo-Durán, Juan J Salazar, José M Ramíre. Changes in visual function and retinal structure in the progression of Alzheimer's disease. PloS one. vol 14. issue 8. 2020-03-05. PMID:31415594. |
alzheimer's disease (ad) can cause degeneration in the retina and optic nerve either directly, as a result of amyloid beta deposits, or secondarily, as a result of the degradation of the visual cortex. |
2020-03-05 |
2023-08-13 |
Not clear |
| Henri Lenoir, Éric Siérof. [Visual perceptual disorders in Alzheimer's disease]. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 17. issue 3. 2020-01-31. PMID:31449049. |
our review covers the recent literature describing visual perception deficits in patients suffering from alzheimer's disease by classifying them according to their neuroanatomical correspondence: retina, visual pathway, subcortical structures, occipital visual cortex, occipito-temporal "what" and occipito-parietal "where" pathways. |
2020-01-31 |
2023-08-13 |
Not clear |
| Anthony J Martorell, Abigail L Paulson, Ho-Jun Suk, Fatema Abdurrob, Gabrielle T Drummond, Webster Guan, Jennie Z Young, David Nam-Woo Kim, Oleg Kritskiy, Scarlett J Barker, Vamsi Mangena, Stephanie M Prince, Emery N Brown, Kwanghun Chung, Edward S Boyden, Annabelle C Singer, Li-Huei Tsa. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. vol 177. issue 2. 2020-01-24. PMID:30879788. |
we previously reported that inducing gamma oscillations with a non-invasive light flicker (gamma entrainment using sensory stimulus or genus) impacted pathology in the visual cortex of alzheimer's disease mouse models. |
2020-01-24 |
2023-08-13 |
mouse |
| Szabolcs Kéri, Zoltán Janka, György Benedek, Péter Aszalós, Botond Szatmáry, Gábor Szirtes, András Lörinc. Categories, prototypes and memory systems in Alzheimer's disease. Trends in cognitive sciences. vol 6. issue 3. 2019-11-20. PMID:11861191. |
simple, self-organizing neuronal networks can explain prototype learning and related dysfunctions in alzheimer's disease, and provide a model of how prototype learning is mediated by circumscribed mechanisms in the visual cortex. |
2019-11-20 |
2023-08-12 |
Not clear |