| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael S Bienkowski, Ian Bowman, Monica Y Song, Lin Gou, Tyler Ard, Kaelan Cotter, Muye Zhu, Nora L Benavidez, Seita Yamashita, Jaspar Abu-Jaber, Sana Azam, Darrick Lo, Nicholas N Foster, Houri Hintiryan, Hong-Wei Don. Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks. Nature neuroscience. vol 21. issue 11. 2019-05-16. PMID:30297807. |
understanding the organization of the hippocampus is fundamental to understanding brain function related to learning, memory, emotions, and diseases such as alzheimer's disease. |
2019-05-16 |
2023-08-13 |
mouse |
| Henna Konttinen, Irina Gureviciene, Minna Oksanen, Alexandra Grubman, Sanna Loppi, Mikko T Huuskonen, Paula Korhonen, Riikka Lampinen, Meike Keuters, Irina Belaya, Heikki Tanila, Katja M Kanninen, Gundars Goldsteins, Gary Landreth, Jari Koistinaho, Tarja Mal. PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. Glia. vol 67. issue 1. 2019-05-15. PMID:30453390. |
defective fatty acid oxidation and mitochondrial dysfunctions correlate with hippocampal neurodegeneration and memory deficits in alzheimer's disease (ad), but it is unclear whether energy metabolism can be targeted to prevent or treat the disease. |
2019-05-15 |
2023-08-13 |
mouse |
| Bo-Wen Wu, Mi-Shan Wu, Jin-Dong Gu. Effects of microRNA-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the BDNF-TrkB signaling pathway in a rat model of Alzheimer's disease. Journal of cellular physiology. vol 233. issue 7. 2019-05-14. PMID:29215712. |
effects of microrna-10a on synapse remodeling in hippocampal neurons and neuronal cell proliferation and apoptosis through the bdnf-trkb signaling pathway in a rat model of alzheimer's disease. |
2019-05-14 |
2023-08-13 |
rat |
| Ni Gao, Li-Xin Tao, Jian Huang, Feng Zhang, Xia Li, Finbarr O'Sullivan, Si-Peng Chen, Si-Jia Tian, Gehendra Mahara, Yan-Xia Luo, Qi Gao, Xiang-Tong Liu, Wei Wang, Zhi-Gang Liang, Xiu-Hua Gu. Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer's disease. Metabolic brain disease. vol 33. issue 6. 2019-05-13. PMID:30178281. |
contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of alzheimer's disease. |
2019-05-13 |
2023-08-13 |
human |
| Ni Gao, Li-Xin Tao, Jian Huang, Feng Zhang, Xia Li, Finbarr O'Sullivan, Si-Peng Chen, Si-Jia Tian, Gehendra Mahara, Yan-Xia Luo, Qi Gao, Xiang-Tong Liu, Wei Wang, Zhi-Gang Liang, Xiu-Hua Gu. Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer's disease. Metabolic brain disease. vol 33. issue 6. 2019-05-13. PMID:30178281. |
the study is aimed to assess whether the addition of contourlet-based hippocampal magnetic resonance imaging (mri) texture features to multivariant models improves the classification of alzheimer's disease (ad) and the prediction of mild cognitive impairment (mci) conversion, and to evaluate whether gaussian process (gp) and partial least squares (pls) are feasible in developing multivariant models in this context. |
2019-05-13 |
2023-08-13 |
human |
| Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martí. Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease. Nature medicine. vol 25. issue 4. 2019-05-10. PMID:30911133. |
adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with alzheimer's disease. |
2019-05-10 |
2023-08-13 |
human |
| Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martí. Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease. Nature medicine. vol 25. issue 4. 2019-05-10. PMID:30911133. |
the hippocampus is one of the most affected areas in alzheimer's disease (ad) |
2019-05-10 |
2023-08-13 |
human |
| Cai-Feng Zhu, Li-da Zhang, Xiao-Ge Song, Jun Yang, Hong-Ping Pan, Cheng-Gong He, Kun Yang, Xiao-Feng Qin, Wan-Li Zh. [Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 4. 2019-05-09. PMID:31056874. |
[moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in app/ps1 transgenic alzheimer's disease mice]. |
2019-05-09 |
2023-08-13 |
mouse |
| Cai-Feng Zhu, Li-da Zhang, Xiao-Ge Song, Jun Yang, Hong-Ping Pan, Cheng-Gong He, Kun Yang, Xiao-Feng Qin, Wan-Li Zh. [Moxibustion improves learning-memory ability by promoting cellular autophagy and regulating autophagy-related proteins in hippocampus and cerebral cortex in APP/PS1 transgenic Alzheimer's disease mice]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 4. 2019-05-09. PMID:31056874. |
to observe the effect of moxibustion of acupoints of the governor vessel on the levels of cellular autophagy, β amyloid protein (aβ) immunoactivity, and expression of lc3-Ⅰ， lc3-Ⅱ， p62 and p-p70s6k proteins in the hippocampal tissue of appswe/ps1de9 (app/ps1) double-transgenic alzheimer's disease (ad) mice, so as to reveal its underlying mechanisms in improving ad. |
2019-05-09 |
2023-08-13 |
mouse |
| Blathnaid Hughes, Caroline E Herro. Cannabidiol Reverses Deficits in Hippocampal LTP in a Model of Alzheimer's Disease. Neurochemical research. vol 44. issue 3. 2019-05-07. PMID:29574668. |
cannabidiol reverses deficits in hippocampal ltp in a model of alzheimer's disease. |
2019-05-07 |
2023-08-13 |
Not clear |
| Zhiren Wang, Jinhui Hu, Xiaoping Yang, Xing Feng, Xingshu Li, Ling Huang, Albert S C Cha. Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease. Journal of medicinal chemistry. vol 61. issue 5. 2019-05-03. PMID:29420891. |
design, synthesis, and evaluation of orally bioavailable quinoline-indole derivatives as innovative multitarget-directed ligands: promotion of cell proliferation in the adult murine hippocampus for the treatment of alzheimer's disease. |
2019-05-03 |
2023-08-13 |
mouse |
| Hyun-Sik Yang, Lei Yu, Charles C White, Lori B Chibnik, Jasmeer P Chhatwal, Reisa A Sperling, David A Bennett, Julie A Schneider, Philip L De Jage. Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study. The Lancet. Neurology. vol 17. issue 9. 2019-05-02. PMID:30093249. |
transactive response dna-binding protein of 43 kda (tdp-43) proteinopathy in older adults frequently coexists with alzheimer's disease pathology and hippocampal sclerosis. |
2019-05-02 |
2023-08-13 |
Not clear |
| Do Won Hwang, Yoori Choi, Dohyun Kim, Hye Yoon Park, Kyu Wan Kim, Mee Young Kim, Chul-Kee Park, Dong Soo Le. Graphene oxide-quenching-based fluorescence in situ hybridization (G-FISH) to detect RNA in tissue: Simple and fast tissue RNA diagnostics. Nanomedicine : nanotechnology, biology, and medicine. vol 16. 2019-04-29. PMID:30594658. |
using a fluorophore-labeled peptide nucleic acid (pna) attached to go, the endogenous long noncoding rna bc1, the constitutive protein β-actin mrna, and mir-124a and mir-21 could be detected in the cytoplasm of a normal mouse brain, primary cultured hippocampal neurons, an alzheimer's disease model mouse brain, and glioblastoma multiforme tumor tissues, respectively. |
2019-04-29 |
2023-08-13 |
mouse |
| Jing Liu, Yan-Jun Du, Qing-Lian Zhou, Guo-Jie Su. [Acupuncture plus moxibustion intervention improves learning-memory ability by suppressing hippocampal JAK2/STAT3 signaling in Alzheimer's rats]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 2. 2019-04-25. PMID:30945481. |
[acupuncture plus moxibustion intervention improves learning-memory ability by suppressing hippocampal jak2/stat3 signaling in alzheimer's rats]. |
2019-04-25 |
2023-08-13 |
rat |
| Jing Liu, Yan-Jun Du, Qing-Lian Zhou, Guo-Jie Su. [Acupuncture plus moxibustion intervention improves learning-memory ability by suppressing hippocampal JAK2/STAT3 signaling in Alzheimer's rats]. Zhen ci yan jiu = Acupuncture research. vol 44. issue 2. 2019-04-25. PMID:30945481. |
to investigate the effect of acupuncture plus moxibustion on learning-memory ability and expression of hippocampal janus kinase-2 (jak2)/signal transducer and activator of transcription-3 (stat3)/suppressors of cytokine signaling-3 (socs3) signaling in alzheimer's disease (ad) rats, so as to reveal their mechanisms underlying improvement of ad. |
2019-04-25 |
2023-08-13 |
rat |
| David Baglietto-Vargas, Elisabeth Sánchez-Mejias, Victoria Navarro, Sebastián Jimenez, Laura Trujillo-Estrada, Angela Gómez-Arboledas, Maria Sánchez-Mico, Raquel Sánchez-Varo, Marisa Vizuete, José Carlos Dávila, José Manuel García-Verdugo, Javier Vitorica, Antonia Gutierre. Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer's disease. Scientific reports. vol 7. issue 1. 2019-04-23. PMID:28855626. |
in this regard, new evidence linking alzheimer's disease-related pathology and neuronal stem cells suggests that hippocampal neurogenesis impairment is an important factor underlying these cognitive deficits. |
2019-04-23 |
2023-08-13 |
mouse |
| Qin Sun, Ling-Ling Wei, Min Zhang, Ting-Xin Li, Chun Yang, Shao-Ping Deng, Qing-Cui Zen. Rapamycin inhibits activation of AMPK-mTOR signaling pathway-induced Alzheimer's disease lesion in hippocampus of rats with type 2 diabetes mellitus. The International journal of neuroscience. vol 129. issue 2. 2019-04-22. PMID:29962282. |
rapamycin inhibits activation of ampk-mtor signaling pathway-induced alzheimer's disease lesion in hippocampus of rats with type 2 diabetes mellitus. |
2019-04-22 |
2023-08-13 |
rat |
| Wanda M Snow, Kensuke Oikawa, Jelena Djordjevic, Benedict C Albens. Strain differences in hippocampal synaptic dysfunction in the TgCRND8 mouse model of Alzheimer's disease: Implications for improving translational capacity. Molecular and cellular neurosciences. vol 94. 2019-04-19. PMID:30404024. |
strain differences in hippocampal synaptic dysfunction in the tgcrnd8 mouse model of alzheimer's disease: implications for improving translational capacity. |
2019-04-19 |
2023-08-13 |
mouse |
| Syed Obaidur Rahman, Bibhu Prasad Panda, Suhel Parvez, Madhu Kaundal, Salman Hussain, Mohd Akhtar, Abul Kalam Najm. Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 110. 2019-04-18. PMID:30463045. |
neuroprotective role of astaxanthin in hippocampal insulin resistance induced by aβ peptides in animal model of alzheimer's disease. |
2019-04-18 |
2023-08-13 |
rat |
| Syed Obaidur Rahman, Bibhu Prasad Panda, Suhel Parvez, Madhu Kaundal, Salman Hussain, Mohd Akhtar, Abul Kalam Najm. Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 110. 2019-04-18. PMID:30463045. |
our study concludes preventive action of astaxanthin against hippocampal insulin resistance and alzheimer's disease complications, supporting potential role of hippocampal insulin resistance targeting against ad. |
2019-04-18 |
2023-08-13 |
rat |