| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Tian, Tienju Wang, Qi Wang, Lan Guo, Heng D. MK0677, a Ghrelin Mimetic, Improves Neurogenesis but Fails to Prevent Hippocampal Lesions in a Mouse Model of Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 72. issue 2. 2020-11-17. PMID:31594237. |
mk0677, a ghrelin mimetic, improves neurogenesis but fails to prevent hippocampal lesions in a mouse model of alzheimer's disease pathology. |
2020-11-17 |
2023-08-13 |
mouse |
| Jing Tian, Tienju Wang, Qi Wang, Lan Guo, Heng D. MK0677, a Ghrelin Mimetic, Improves Neurogenesis but Fails to Prevent Hippocampal Lesions in a Mouse Model of Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 72. issue 2. 2020-11-17. PMID:31594237. |
hippocampal lesions including synaptic injury, neuroinflammation, and impaired neurogenesis are featured pathology closely associated with neuronal stress and cognitive impairment in alzheimer's disease (ad). |
2020-11-17 |
2023-08-13 |
mouse |
| Boo-Kyeong Choi, Nuwan Madusanka, Heung-Kook Choi, Jae-Hong So, Cho-Hee Kim, Hyeon-Gyun Park, Subrata Bhattacharjee, Deekshitha Prakas. Convolutional Neural Network-based MR Image Analysis for Alzheimer's Disease Classification. Current medical imaging reviews. vol 16. issue 1. 2020-11-17. PMID:31989891. |
in this study, we used a convolutional neural network (cnn) to classify alzheimer's disease (ad), mild cognitive impairment (mci), and normal control (nc) subjects based on images of the hippocampus region extracted from magnetic resonance (mr) images of the brain. |
2020-11-17 |
2023-08-13 |
human |
| Siti Nurbaya Yaakub, Rolf A Heckemann, Simon S Keller, Colm J McGinnity, Bernd Weber, Alexander Hammer. On brain atlas choice and automatic segmentation methods: a comparison of MAPER & FreeSurfer using three atlas databases. Scientific reports. vol 10. issue 1. 2020-11-13. PMID:32071355. |
we also used each possible combination to segment two datasets of patients with known structural abnormalities (alzheimer's disease (ad) and mesial temporal lobe epilepsy with hippocampal sclerosis (hs)) and their matched healthy controls. |
2020-11-13 |
2023-08-13 |
Not clear |
| Qing Zheng, Li-Hong Kong, Chao-Chao Yu, Rui-Yang He, Xue-Song Wang, Tao Jiang, Ran Ma, Yun-Yun Chen, Yue-Shen Wan. [Effects of electroacupuncture on cognitive function and neuronal autophagy in rats with D-galactose induced Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 9. 2020-11-12. PMID:32959549. |
to observe the effect of electroacupuncture at "baihui"(gv20) and "shenshu"(bl23) on the expression of autophagy-related proteins in the hippocampus of rats with alzheimer's disease (ad)，so as to explore its underlying mechanisms on improvement of ad. |
2020-11-12 |
2023-08-13 |
rat |
| Susana Estévez-Santé, Adolfo Jiménez-Huet. Comparative analysis of methods of volume adjustment in hippocampal volumetry for the diagnosis of Alzheimer disease. Journal of neuroradiology = Journal de neuroradiologie. vol 47. issue 2. 2020-11-12. PMID:30857897. |
comparative analysis of methods of volume adjustment in hippocampal volumetry for the diagnosis of alzheimer disease. |
2020-11-12 |
2023-08-13 |
human |
| Susana Estévez-Santé, Adolfo Jiménez-Huet. Comparative analysis of methods of volume adjustment in hippocampal volumetry for the diagnosis of Alzheimer disease. Journal of neuroradiology = Journal de neuroradiologie. vol 47. issue 2. 2020-11-12. PMID:30857897. |
hippocampal volumetry can discriminate normal subjects from patients with amnestic mild cognitive impairment (mci) or alzheimer disease (ad). |
2020-11-12 |
2023-08-13 |
human |
| Josué Luiz Dalboni da Rocha, Ivanei Bramati, Gabriel Coutinho, Fernanda Tovar Moll, Ranganatha Sitara. Fractional Anisotropy changes in Parahippocampal Cingulum due to Alzheimer's Disease. Scientific reports. vol 10. issue 1. 2020-11-12. PMID:32060334. |
bilateral intersection of hippocampal cingulum and parahippocampal gyrus (referred as parahippocampal cingulum) is the region that best discriminates alzheimer's disease fractional anisotropy values, resulting in an accuracy of 93% for discriminating between alzheimer's disease and controls, and 90% between alzheimer's disease and mild cognitive impairment. |
2020-11-12 |
2023-08-13 |
human |
| Naoki Saji, Kenta Murotani, Takayoshi Hisada, Tsuyoshi Tsuduki, Taiki Sugimoto, Ai Kimura, Shumpei Niida, Kenji Toba, Takashi Sakura. The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan. Scientific reports. vol 9. issue 1. 2020-11-09. PMID:31852995. |
furthermore, patients with more bacteroides were more likely to present with white matter hyperintensity and high voxel-based specific regional analysis system for alzheimer's disease (vsrad) scores, indicating cortical and hippocampal atrophy. |
2020-11-09 |
2023-08-13 |
Not clear |
| Arnaud Charil, Sergey Shcherbinin, Sudeepti Southekal, Michael D Devous, Mark Mintun, Melissa E Murray, Bradley B Miller, Adam J Schwar. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476153. |
at autopsy, individuals with alzheimer's disease (ad) exhibit heterogeneity in the distribution of neurofibrillary tangles in neocortical and hippocampal regions. |
2020-11-05 |
2023-08-13 |
human |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
hippocampal synaptic plasticity disruption by amyloid-β (aβ) peptides + thought to be responsible for learning and memory impairments in alzheimer's disease (ad) early stage. |
2020-11-04 |
2023-08-13 |
mouse |
| Alejandro Martín-Belmonte, Carolina Aguado, Rocío Alfaro-Ruíz, Makoto Itakura, Ana Esther Moreno-Martínez, Luis de la Ossa, Elek Molnár, Yugo Fukazawa, Rafael Lujá. Age-Dependent Shift of AMPA Receptors From Synapses to Intracellular Compartments in Alzheimer's Disease: Immunocytochemical Analysis of the CA1 Hippocampal Region in APP/PS1 Transgenic Mouse Model. Frontiers in aging neuroscience. vol 12. 2020-11-03. PMID:33132900. |
age-dependent shift of ampa receptors from synapses to intracellular compartments in alzheimer's disease: immunocytochemical analysis of the ca1 hippocampal region in app/ps1 transgenic mouse model. |
2020-11-03 |
2023-08-13 |
mouse |
| Kristine B Walhovd, Anders M Fjell, Øystein Sørensen, Athanasia Monika Mowinckel, Céline Sonja Reinbold, Ane-Victoria Idland, Leiv Otto Watne, Andre Franke, Valerija Dobricic, Fabian Kilpert, Lars Bertram, Yunpeng Wan. Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan. Neurology. Genetics. vol 6. issue 5. 2020-11-03. PMID:33134508. |
genetic risk for alzheimer disease predicts hippocampal volume through the human lifespan. |
2020-11-03 |
2023-08-13 |
human |
| Xuemei Quan, Huo Liang, Ya Chen, Qixiong Qin, Yunfei Wei, Zhijian Lian. Related Network and Differential Expression Analyses Identify Nuclear Genes and Pathways in the Hippocampus of Alzheimer Disease. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-03. PMID:31989994. |
related network and differential expression analyses identify nuclear genes and pathways in the hippocampus of alzheimer disease. |
2020-11-03 |
2023-08-13 |
Not clear |
| Liangliang Zhang, Chae Young Lim, Tapabrata Maiti, Yingjie Li, Jongeun Choi, Andrea Bozoki, David C Zh. Analysis of conversion of Alzheimer's disease using a multi-state Markov model. Statistical methods in medical research. vol 28. issue 9. 2020-11-02. PMID:30039745. |
in this paper, we model progression of alzheimer's disease using a multi-state markov model to investigate the significance of known risk factors such as age, apolipoprotein e4, and some brain structural volumetric variables from magnetic resonance imaging scans (e.g., hippocampus, etc.) |
2020-11-02 |
2023-08-13 |
Not clear |
| Ming Wang, Jihoon Jo, Juhyun Son. Adiponectin improves long-term potentiation in the 5XFAD mouse brain. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31222110. |
as recent studies have associated changes in adipokines and other metabolites in the central nervous system with a risk for alzheimer's disease (ad), we investigated the effects of adiponectin treatment on hippocampal cells in the 5xfad mouse model of ad and neuronal sh-sy5y cells under amyloid beta toxicity. |
2020-11-02 |
2023-08-13 |
mouse |
| Ming Wang, Jihoon Jo, Juhyun Son. Adiponectin improves long-term potentiation in the 5XFAD mouse brain. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31222110. |
thus, adiponectin exhibits beneficial effect on hippocampal synaptic plasticity in alzheimer's disease mouse model. |
2020-11-02 |
2023-08-13 |
mouse |
| Hancan Zhu, Zhenyu Tang, Hewei Cheng, Yihong Wu, Yong Fa. Multi-atlas label fusion with random local binary pattern features: Application to hippocampus segmentation. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31727982. |
the rlbp based mais algorithm has been validated for segmenting hippocampus based on a data set of 135 t1 mr images which are from the alzheimer's disease neuroimaging initiative database (adni.loni.usc.edu). |
2020-11-02 |
2023-08-13 |
human |
| Hancan Zhu, Zhenyu Tang, Hewei Cheng, Yihong Wu, Yong Fa. Multi-atlas label fusion with random local binary pattern features: Application to hippocampus segmentation. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31727982. |
these results have demonstrated that the rlbp based multi-atlas image segmentation method could facilitate efficient and accurate extraction of the hippocampus and may help predict alzheimer's disease. |
2020-11-02 |
2023-08-13 |
human |
| Maria-Eleni Dounavi, Elijah Mak, Katie Wells, Karen Ritchie, Craig W Ritchie, Li Su, John T O' Brie. Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. Neurobiology of aging. vol 91. 2020-10-30. PMID:32311609. |
the hippocampus is one of the first regions to demonstrate atrophy during the prodromal stage of alzheimer's disease. |
2020-10-30 |
2023-08-13 |
human |