| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Montero-Crespo, Marta Domínguez-Álvaro, Lidia Alonso-Nanclares, Javier DeFelipe, Lidia Blazquez-Llorc. Three-dimensional analysis of synaptic organization in the hippocampal CA1 field in Alzheimer's disease. Brain : a journal of neurology. vol 144. issue 2. 2021-04-19. PMID:33324984. |
three-dimensional analysis of synaptic organization in the hippocampal ca1 field in alzheimer's disease. |
2021-04-19 |
2023-08-13 |
human |
| Shasha Song, Jingjiong Chen, Pinpin Xiao, Hao Duan, Yajun Zhou, Feng Wang, Hongmei Wang, Yuwu Zhao, Zhi Gen. Role of Macrophages in Status Epilepticus Predisposing to Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31796682. |
continuous epileptic seizures hallmark status epilepticus, leading to preferential neuronal cell loss in the hippocampus that can progress into alzheimer's disease. |
2021-04-19 |
2023-08-13 |
rat |
| Jin-Ting He, Xin Zhao, Lei Xu, Cui-Ying Ma. Vascular Risk Factors and Alzheimer's Disease: Blood-Brain Barrier Disruption, Metabolic Syndromes, and Molecular Links. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31815697. |
alzheimer's disease (ad) is a neurodegenerative disorder, marked by cortical and hippocampal deposition of amyloid-β (aβ) plaques and neurofibrillary tangles and cognitive impairment. |
2021-04-19 |
2023-08-13 |
Not clear |
| Natalie Tomaszewski, Xulei He, Victoria Solomon, Mitchell Lee, Wendy J Mack, Joseph F Quinn, Meredith N Braskie, Hussein N Yassin. Effect of APOE Genotype on Plasma Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid, Arachidonic Acid, and Hippocampal Volume in the Alzheimer's Disease Cooperative Study-Sponsored DHA Clinical Trial. Journal of Alzheimer's disease : JAD. vol 74. issue 3. 2021-04-19. PMID:32116250. |
effect of apoe genotype on plasma docosahexaenoic acid (dha), eicosapentaenoic acid, arachidonic acid, and hippocampal volume in the alzheimer's disease cooperative study-sponsored dha clinical trial. |
2021-04-19 |
2023-08-13 |
Not clear |
| Francesca Rocchio, Laura Tapella, Marcello Manfredi, Mariangela Chisari, Francesca Ronco, Federico Alessandro Ruffinatti, Eleonora Conte, Pier Luigi Canonico, Maria Angela Sortino, Mariagrazia Grilli, Emilio Marengo, Armando A Genazzani, Dmitry Li. Correction: Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model. Cell death & disease. vol 11. issue 4. 2021-04-16. PMID:32300109. |
correction: gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an alzheimer's disease mouse model. |
2021-04-16 |
2023-08-13 |
mouse |
| Wei Ge, Chao Ren, Lei Xing, Lina Guan, Caiyi Zhang, Xuwen Sun, Guoping Wang, Haichen Niu, Sen Qu. Ginkgo biloba extract improves cognitive function and increases neurogenesis by reducing Aβ pathology in 5×FAD mice. American journal of translational research. vol 13. issue 3. 2021-04-13. PMID:33841671. |
previous studies have indicated that the generation of newborn hippocampal neurons is impaired in the early phase of alzheimer's disease (ad). |
2021-04-13 |
2023-08-13 |
mouse |
| Matthias Gralle, Simon Labrecque, Charleen Salesse, Paul De Koninc. Spatial dynamics of the insulin receptor in living neurons. Journal of neurochemistry. vol 156. issue 1. 2021-04-12. PMID:31886886. |
it has been proposed that hippocampal insulin signaling is important for memory, that brain insulin signaling is deficient in alzheimer's disease, and that intranasal insulin treatment improves cognition, but the mechanisms remain unclear and do not seem to involve increased glucose uptake by neurons. |
2021-04-12 |
2023-08-13 |
rat |
| Lauren N Woodie, Robert M Johnson, Bulbul Ahmed, Savanah Fowler, William Haynes, Beatriz Carmona, Miranda Reed, Vishnu Suppiramaniam, Michael W Green. Western diet-induced obesity disrupts the diurnal rhythmicity of hippocampal core clock gene expression in a mouse model. Brain, behavior, and immunity. vol 88. 2021-04-06. PMID:32454134. |
however, all measured core clock genes were disrupted in the hippocampus after wd feeding and the expression pattern of genes implicated in alzheimer's disease and synaptic function were altered. |
2021-04-06 |
2023-08-13 |
mouse |
| Hyeon Jeong Seo, Jung Eun Park, Seong-Min Choi, Taekyoung Kim, Soo Hyun Cho, Kyung-Hwa Lee, Woo Keun Song, Juhyun Song, Han-Seong Jeong, Dong Hyun Kim, Byeong C Ki. Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 2. 2021-04-02. PMID:33445678. |
alzheimer's disease (ad) is a neurodegenerative disorder characterized by a rapid accumulation of amyloid β (aβ) protein in the hippocampus, which impairs synaptic structures and neuronal signal transmission, induces neuronal loss, and diminishes memory and cognitive functions. |
2021-04-02 |
2023-08-13 |
mouse |
| Xianfeng Huang, Jinyao Yang, Xi Huang, Zaijun Zhang, Jianjun Liu, Liangyu Zou, Xifei Yan. Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease. Frontiers in cell and developmental biology. vol 9. 2021-04-02. PMID:33791294. |
tetramethylpyrazine improves cognitive impairment and modifies the hippocampal proteome in two mouse models of alzheimer's disease. |
2021-04-02 |
2023-08-13 |
mouse |
| A O Burnyasheva, N A Stefanova, E A Rudnitskay. [Adult neurogenesis: alterations with aging and Alzheimer's disease development.] Advances in gerontology = Uspekhi gerontologii. vol 33. issue 6. 2021-03-30. PMID:33774989. |
hippocampus and entorhinal cortex are the key neurogenic niches in the adult brain and one of the most vulnerable brain areas during the development of alzheimer's disease. |
2021-03-30 |
2023-08-13 |
Not clear |
| Siqi Wang, Shengwei Ke, Yueming Wu, Duo Zhang, Baowei Liu, Yao-Hui He, Wen Liu, Huawei Mu, Xiaoyuan Son. Functional Network of the Long Non-coding RNA Growth Arrest-Specific Transcript 5 and Its Interacting Proteins in Senescence. Frontiers in genetics. vol 12. 2021-03-30. PMID:33777096. |
rna pull-down assay using mouse brain hippocampus tissues showed that potential gas5 interacting proteins could be enriched into several kyoto encyclopedia of genes and genomes (kegg) pathways, and some of them are involved in senescence-associated diseases such as parkinson's and alzheimer's diseases. |
2021-03-30 |
2023-08-13 |
mouse |
| Marianne Chapleau, Christophe Bedetti, Gabriel A Devenyi, Signy Sheldon, Howie J Rosen, Bruce L Miller, Maria Luisa Gorno-Tempini, Mallar M Chakravarty, Simona M Brambat. Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease. NeuroImage. Clinical. vol 27. 2021-03-29. PMID:32544853. |
deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and alzheimer's disease. |
2021-03-29 |
2023-08-13 |
human |
| Marianne Chapleau, Christophe Bedetti, Gabriel A Devenyi, Signy Sheldon, Howie J Rosen, Bruce L Miller, Maria Luisa Gorno-Tempini, Mallar M Chakravarty, Simona M Brambat. Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease. NeuroImage. Clinical. vol 27. 2021-03-29. PMID:32544853. |
the goal of the present study is to conduct a detailed characterization of the impact of svppa on global hippocampus volume and morphology compared with control subjects and patients with alzheimer's disease (ad). |
2021-03-29 |
2023-08-13 |
human |
| Emma Coninx, Yap Ching Chew, Xiaojing Yang, Wei Guo, Amelie Coolkens, Sarah Baatout, Lieve Moons, Mieke Verslegers, Roel Quinten. Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer's disease. Aging. vol 12. issue 20. 2021-03-29. PMID:33082299. |
hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for alzheimer's disease. |
2021-03-29 |
2023-08-13 |
mouse |
| Doha M Beltagy, Nagat F Nawar, Tarek M Mohamed, Ehab Tousson, Mai M El-Kee. Beneficial consequences of probiotic on mitochondrial hippocampus in Alzheimer's disease. Journal of complementary & integrative medicine. 2021-03-29. PMID:33781011. |
beneficial consequences of probiotic on mitochondrial hippocampus in alzheimer's disease. |
2021-03-29 |
2023-08-13 |
Not clear |
| Wei Xu, Bing-Jie Su, Xue-Ning Shen, Yan-Lin Bi, Chen-Chen Tan, Jie-Qiong Li, Xi-Peng Cao, Qiang Dong, Lan Tan, Jin-Tai Y. Plasma sex hormone-binding globulin predicts neurodegeneration and clinical progression in prodromal Alzheimer's disease. Aging. vol 12. issue 14. 2021-03-24. PMID:32699184. |
next, the influences of plasma shbg on dynamic changes of csf aβ42, hippocampus volume, brain metabolism, and cognition were explored in 448 non-demented adults from the alzheimer's disease neuroimaging initiative (adni). |
2021-03-24 |
2023-08-13 |
Not clear |
| Anne Sieben, Tim Van Langenhove, Yannick Vermeiren, Helena Gossye, Marleen Praet, Dimitri Vanhauwaert, Céline Cousaert, Sebastiaan Engelborghs, Robrecht Raedt, Paul Boon, Patrick Santens, Peter Paul De Deyn, Ken R Bracke, Katia De Meulemeester, Christine Van Broeckhoven, Jean-Jacques Martin, Maria Bjerk. Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration. Journal of neuropathology and experimental neurology. vol 80. issue 4. 2021-03-24. PMID:33638350. |
we examined the relationship between hs, proteinopathies in frontotemporal cortices and hippocampus, alzheimer disease, cerebrovascular changes, and age. |
2021-03-24 |
2023-08-13 |
Not clear |
| Yingqian Liu, Zhuangzhi Ya. A Combined Deep-Learning and Lattice Boltzmann Model for Segmentation of the Hippocampus in MRI. Sensors (Basel, Switzerland). vol 20. issue 13. 2021-03-22. PMID:32605230. |
segmentation of the hippocampus (hc) in magnetic resonance imaging (mri) is an essential step for diagnosis and monitoring of several clinical situations such as alzheimer's disease (ad), schizophrenia and epilepsy. |
2021-03-22 |
2023-08-13 |
Not clear |
| Carla Petrella, Maria Teresa Ciotti, Robert Nisticò, Sonia Piccinin, Pietro Calissano, Simona Capsoni, Delio Mercanti, Sebastiano Cavallaro, Roberta Possenti, Cinzia Severin. Involvement of Bradykinin Receptor 2 in Nerve Growth Factor Neuroprotective Activity. Cells. vol 9. issue 12. 2021-03-22. PMID:33321704. |
the aim of the present study is to investigate the involvement of b2r in the ngf mechanism of action in nonsensory neurons in vitro by using rat mixed cortical primary cultures (cns) and mouse hippocampal slices, and in vivo in alzheimer's disease (ad) transgenic mice (5xfad) chronically treated with ngf. |
2021-03-22 |
2023-08-13 |
mouse |