| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Rabattoni, Loredano Pollegioni, Gabriella Tedeschi, Elisa Maffioli, Silvia Sacch. Cellular studies of the two main isoforms of human d-aspartate oxidase. The FEBS journal. vol 288. issue 16. 2021-09-07. PMID:33650155. |
here, the additional n-terminal peptide present in the hdaspo_369 isoform only has been identified in hippocampus of alzheimer's disease female patients, while peptides corresponding to the remaining part of the protein were present in samples from male and female healthy controls and alzheimer's disease patients. |
2021-09-07 |
2023-08-13 |
human |
| Peiyun Yan, Zhancheng Xue, Dezhu Li, Saiqi Ni, Chuang Wang, Xinchun Jin, Dongsheng Zhou, Xingxing Li, Xin Zhao, Xiaowei Chen, Wei Cui, Dingli Xu, Wenhua Zhou, Junfang Zhan. Dysregulated CRTC1-BDNF signaling pathway in the hippocampus contributes to Aβ oligomer-induced long-term synaptic plasticity and memory impairment. Experimental neurology. vol 345. 2021-09-07. PMID:34274327. |
expression of creb-regulated transcription coactivator 1 (crtc1) in the hippocampus is impaired in alzheimer's disease (ad). |
2021-09-07 |
2023-08-13 |
rat |
| Shin Jie Yong, Min Hooi Yong, Seong Lin Teoh, Tomoko Soga, Ishwar Parhar, Jactty Chew, Wei Ling Li. The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer's Disease and Memory Impairment. Frontiers in cellular neuroscience. vol 15. 2021-09-07. PMID:34483839. |
the hippocampal vulnerability to herpes simplex virus type i infection: relevance to alzheimer's disease and memory impairment. |
2021-09-07 |
2023-08-13 |
human |
| Yuhan Ma, Jing Wang, Dihui Xu, Yabing Chen, Xiaodong Ha. Chronic MC-LR exposure promoted Aβ and p-tau accumulation via regulating Akt/GSK-3β signal pathway. The Science of the total environment. vol 794. 2021-09-06. PMID:34323745. |
in this study, we observed β-amyloid (aβ) accumulation and tau hyperphosphorylation (p-tau) at sites of ser396 and thr205 in mouse hippocampus and cortex, alzheimer's disease (ad) like changes, after chronic exposure to mc-lr at different concentrations (1, 7.5, 15 and 30 μg/l) for 180 days. |
2021-09-06 |
2023-08-13 |
mouse |
| Hongyoon Choi, Yoori Choi, Eun Ji Lee, Hyun Kim, Youngsun Lee, Seokjun Kwon, Do Won Hwang, Dong Soo Le. Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer's disease. Journal of neuroinflammation. vol 18. issue 1. 2021-09-04. PMID:34465358. |
hippocampal glucose uptake as a surrogate of metabolic change of microglia in alzheimer's disease. |
2021-09-04 |
2023-08-13 |
Not clear |
| Lin Li, Xin-Kang Tong, Mohammadamin Hosseini Kahnouei, Diane Vallerand, Edith Hamel, Hélène Girouar. Impaired Hippocampal Neurovascular Coupling in a Mouse Model of Alzheimer's Disease. Frontiers in physiology. vol 12. 2021-09-04. PMID:34475828. |
impaired hippocampal neurovascular coupling in a mouse model of alzheimer's disease. |
2021-09-04 |
2023-08-13 |
mouse |
| Heechul Jun, Jasmine Chavez, Allen Bramian, Kei M Igarash. Protocol for remapping of place cells in disease mouse models. STAR protocols. vol 2. issue 3. 2021-09-03. PMID:34467228. |
hippocampal place cells and entorhinal grid cells exhibit distinct spike patterns in different environments called "remapping," and we have recently shown that remapping of place cells becomes disrupted in a mouse model of alzheimer's disease. |
2021-09-03 |
2023-08-13 |
mouse |
| Vergine Chavushyan, Senik Matinyan, Margarita Danielyan, Michail Aghajanov, Konstantin Yenkoya. Embryonic proteoglycans regulate monoamines in the rat frontal cortex and hippocampus in Alzheimer's disease-like pathology. Neurochemistry international. vol 140. 2021-09-02. PMID:32853753. |
embryonic proteoglycans regulate monoamines in the rat frontal cortex and hippocampus in alzheimer's disease-like pathology. |
2021-09-02 |
2023-08-13 |
rat |
| Vergine Chavushyan, Senik Matinyan, Margarita Danielyan, Michail Aghajanov, Konstantin Yenkoya. Embryonic proteoglycans regulate monoamines in the rat frontal cortex and hippocampus in Alzheimer's disease-like pathology. Neurochemistry international. vol 140. 2021-09-02. PMID:32853753. |
using the rat alzheimer's disease (ad)-like model we have analyzed the hippocampal short-term potentiation, levels of monoamines, and morphological changes in the hippocampal and cortical neurons after the administration of proteoglycans of embryonic origin (peg). |
2021-09-02 |
2023-08-13 |
rat |
| Hweeling Lee, Rüdiger Stirnberg, Sichu Wu, Xin Wang, Tony Stöcker, Sonja Jung, Christian Montag, Nikolai Axmache. Genetic Alzheimer's Disease Risk Affects the Neural Mechanisms of Pattern Separation in Hippocampal Subfields. Current biology : CB. vol 30. issue 21. 2021-09-02. PMID:32916120. |
genetic alzheimer's disease risk affects the neural mechanisms of pattern separation in hippocampal subfields. |
2021-09-02 |
2023-08-13 |
Not clear |
| Hweeling Lee, Rüdiger Stirnberg, Sichu Wu, Xin Wang, Tony Stöcker, Sonja Jung, Christian Montag, Nikolai Axmache. Genetic Alzheimer's Disease Risk Affects the Neural Mechanisms of Pattern Separation in Hippocampal Subfields. Current biology : CB. vol 30. issue 21. 2021-09-02. PMID:32916120. |
the hippocampal subfields perform distinct operations during acquisition, differentiation, and recollection of episodic memories, and deficits in pattern separation are among the first symptoms of alzheimer's disease (ad). |
2021-09-02 |
2023-08-13 |
Not clear |
| Pegah Javadpour, Sahar Askari, Fatemeh Sadat Rashidi, Leila Dargahi, Abolhassan Ahmadiani, Rasoul Ghasem. Imipramine alleviates memory impairment and hippocampal apoptosis in STZ-induced sporadic Alzheimer's rat model: Possible contribution of MAPKs and insulin signaling. Behavioural brain research. vol 408. 2021-09-02. PMID:33775777. |
imipramine alleviates memory impairment and hippocampal apoptosis in stz-induced sporadic alzheimer's rat model: possible contribution of mapks and insulin signaling. |
2021-09-02 |
2023-08-13 |
rat |
| Nandkishor Kotagale, Rupali Deshmukh, Madhura Dixit, Rajshree Fating, Milind Umekar, Brijesh Taksand. Agmatine ameliorates manifestation of depression-like behavior and hippocampal neuroinflammation in mouse model of Alzheimer's disease. Brain research bulletin. vol 160. 2021-08-31. PMID:32344125. |
agmatine ameliorates manifestation of depression-like behavior and hippocampal neuroinflammation in mouse model of alzheimer's disease. |
2021-08-31 |
2023-08-13 |
mouse |
| Md Ataur Rahman, Md Abdul Hannan, Md Jamal Uddin, Md Saidur Rahman, Md Mamunur Rashid, Bonglee Ki. Exposure to Environmental Arsenic and Emerging Risk of Alzheimer's Disease: Perspective Mechanisms, Management Strategy, and Future Directions. Toxics. vol 9. issue 8. 2021-08-31. PMID:34437506. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases, characterized by memory dysfunction and the presence of hyperphosphorylated tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2021-08-31 |
2023-08-13 |
human |
| Jin Li, Wenjie Liu, Luolong Cao, Haoran Luo, Siwen Xu, Peihua Bao, Xianglian Meng, Hong Liang, Shiaofen Fan. Hippocampal Subregion and Gene Detection in Alzheimer's Disease Based on Genetic Clustering Random Forest. Genes. vol 12. issue 5. 2021-08-30. PMID:34062866. |
hippocampal subregion and gene detection in alzheimer's disease based on genetic clustering random forest. |
2021-08-30 |
2023-08-13 |
Not clear |
| Jin Li, Wenjie Liu, Luolong Cao, Haoran Luo, Siwen Xu, Peihua Bao, Xianglian Meng, Hong Liang, Shiaofen Fan. Hippocampal Subregion and Gene Detection in Alzheimer's Disease Based on Genetic Clustering Random Forest. Genes. vol 12. issue 5. 2021-08-30. PMID:34062866. |
the distinguishable subregions that compose the hippocampus are differently involved in functions associated with alzheimer's disease (ad). |
2021-08-30 |
2023-08-13 |
Not clear |
| Shahrzad Ghafary, Roshanak Ghobadian, Mohammad Mahdavi, Hamid Nadri, Alireza Moradi, Tahmineh Akbarzadeh, Zahra Najafi, Mohammad Sharifzadeh, Najmeh Edraki, Farshad Homayouni Moghadam, Mohsen Amin. Design, synthesis, and evaluation of novel cinnamic acid-tryptamine hybrid for inhibition of acetylcholinesterase and butyrylcholinesterase. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 28. issue 2. 2021-08-27. PMID:32372339. |
acetylcholine deficiencies in hippocampus and cortex, aggregation of β-amyloid, and β-secretase over activity have been introduced as main reasons in pathogenesis of alzheimer's disease. |
2021-08-27 |
2023-08-13 |
Not clear |
| Olayemi Joseph Olajide, Clifton Andrew Chapma. Amyloid-β (1-42) peptide induces rapid NMDA receptor-dependent alterations at glutamatergic synapses in the entorhinal cortex. Neurobiology of aging. vol 105. 2021-08-27. PMID:34144329. |
the hippocampus and entorhinal cortex (ec) accumulate amyloid beta peptides (aβ) that promote neuropathology in alzheimer's disease, but the early effects of aβ on excitatory synaptic transmission in the ec have not been well characterized. |
2021-08-27 |
2023-08-13 |
Not clear |
| Hilaree N Frazier, Katie L Anderson, Adam O Ghoweri, Ruei-Lung Lin, Tara R Hawkinson, Gabriel J Popa, Pradoldej Sompol, Michael D Mendenhall, Christopher M Norris, Olivier Thibaul. Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats. Aging cell. vol 19. issue 10. 2021-08-26. PMID:32852134. |
as demonstrated by increased hippocampal insulin receptor density following learning in animal models and decreased insulin signaling, receptor density, and memory decline in aging and alzheimer's diseases, numerous studies have emphasized the importance of insulin in learning and memory processes. |
2021-08-26 |
2023-08-13 |
human |
| Jie Zheng, Yawen L. Compensation for Neurodegeneration by Hippocampal Neurogenesis in Alzheimer's Disease: Where is the Way? Neuroscience bulletin. vol 37. issue 6. 2021-08-26. PMID:33905098. |
compensation for neurodegeneration by hippocampal neurogenesis in alzheimer's disease: where is the way? |
2021-08-26 |
2023-08-13 |
Not clear |