| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Almothana Alkasabera, Chike B Onyali, Comfort Anim-Koranteng, Hira E Shah, Aarthi Ethirajulu, Nitin Bhawnani, Jihan A Mostaf. The Effect of Type-2 Diabetes on Cognitive Status and the Role of Anti-diabetes Medications. Cureus. vol 13. issue 11. 2021-12-11. PMID:34877187. |
thirdly, multiple pathological studies showed that insulin and alzheimer's disease share many common lesions in the brain, such as beta-amyloid plaques, amylin-aβ plaques, hyper-phosphorylated tau protein, and brain atrophy, especially in the hippocampus. |
2021-12-11 |
2023-08-13 |
human |
| Judit Català-Solsona, Alfredo J Miñano-Molina, José Rodríguez-Álvare. Nr4a2 Transcription Factor in Hippocampal Synaptic Plasticity, Memory and Cognitive Dysfunction: A Perspective Review. Frontiers in molecular neuroscience. vol 14. 2021-12-11. PMID:34880728. |
hippocampal synaptic dysfunction is widely accepted to underlie the cognitive decline observed in some neurodegenerative disorders including alzheimer's disease. |
2021-12-11 |
2023-08-13 |
Not clear |
| Younes Adam Tabi, Maria Raquel Maio, Bahaaeddin Attaallah, Shannon Dickson, Daniel Drew, Mohamad Imran Idris, Annika Kienast, Verena Klar, Lisa Nobis, Olivia Plant, Youssuf Saleh, Timothy Ravinder Sandhu, Ellie Slavkova, Sofia Toniolo, Nahid Zokaei, Sanjay G Manohar, Masud Husai. Vividness of visual imagery questionnaire scores and their relationship to visual short-term memory performance. Cortex; a journal devoted to the study of the nervous system and behavior. vol 146. 2021-12-11. PMID:34894605. |
here we examined the relationship of visual imagery to stm and hippocampal and primary visual cortex volumes, first in a large sample of healthy people across a large age range (n = 229 behavioural data; n = 56 mri data in older participants) and then in patients with alzheimer's disease and parkinson's disease (n = 19 in each group compared to 19 age-matched healthy controls). |
2021-12-11 |
2023-08-13 |
human |
| Younes Adam Tabi, Maria Raquel Maio, Bahaaeddin Attaallah, Shannon Dickson, Daniel Drew, Mohamad Imran Idris, Annika Kienast, Verena Klar, Lisa Nobis, Olivia Plant, Youssuf Saleh, Timothy Ravinder Sandhu, Ellie Slavkova, Sofia Toniolo, Nahid Zokaei, Sanjay G Manohar, Masud Husai. Vividness of visual imagery questionnaire scores and their relationship to visual short-term memory performance. Cortex; a journal devoted to the study of the nervous system and behavior. vol 146. 2021-12-11. PMID:34894605. |
despite hippocampal volumes also being reduced in alzheimer's patients, there appeared to be no impact on their self-reported visual imagery. |
2021-12-11 |
2023-08-13 |
human |
| Younes Adam Tabi, Maria Raquel Maio, Bahaaeddin Attaallah, Shannon Dickson, Daniel Drew, Mohamad Imran Idris, Annika Kienast, Verena Klar, Lisa Nobis, Olivia Plant, Youssuf Saleh, Timothy Ravinder Sandhu, Ellie Slavkova, Sofia Toniolo, Nahid Zokaei, Sanjay G Manohar, Masud Husai. Vividness of visual imagery questionnaire scores and their relationship to visual short-term memory performance. Cortex; a journal devoted to the study of the nervous system and behavior. vol 146. 2021-12-11. PMID:34894605. |
in conclusion, visual imagery was not significantly related to visual stm performance, either in healthy controls or alzheimer's or parkinson's disease but it was related to hippocampal and visual cortex volume in healthy people. |
2021-12-11 |
2023-08-13 |
human |
| Li-Xia Dong, Hai-Lan Bao, Yan-Yun Zhang, Yu Liu, Guo-Wei Zhang, Feng-Mao A. MicroRNA-16-5p/BTG2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in Alzheimer's disease. Brain research bulletin. vol 175. 2021-12-10. PMID:34217799. |
microrna-16-5p/btg2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in alzheimer's disease. |
2021-12-10 |
2023-08-13 |
Not clear |
| Xiaoxiao Lin, Lujia Chen, David Baglietto-Vargas, Parsa Kamalipour, Qiao Ye, Frank M LaFerla, Douglas A Nitz, Todd C Holmes, Xiangmin X. Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. Neurobiology of disease. vol 162. 2021-12-10. PMID:34838667. |
spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic alzheimer's disease mouse model. |
2021-12-10 |
2023-08-13 |
mouse |
| Xiaoxiao Lin, Lujia Chen, David Baglietto-Vargas, Parsa Kamalipour, Qiao Ye, Frank M LaFerla, Douglas A Nitz, Todd C Holmes, Xiangmin X. Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model. Neurobiology of disease. vol 162. 2021-12-10. PMID:34838667. |
here we examine large-scale hippocampal neural population calcium activities imaged at single cell resolution in a triple-transgenic alzheimer's disease mouse model (3xtg-ad) that presents both amyloid plaque and neurofibrillary pathological features along with age-related behavioral defects. |
2021-12-10 |
2023-08-13 |
mouse |
| Jian-Jun Zhang, Ze-Xuan-Zhu, Guang-Min-Xu, Peng Su, Qian Lei, Wei L. Comprehensive Analysis of Differential Expression Profiles of Long Non-coding RNAs with Associated Co-expression and Competing Endogenous RNA Networks in the Hippocampus of Patients with Alzheimer's Disease. Current Alzheimer research. 2021-12-03. PMID:34856901. |
comprehensive analysis of differential expression profiles of long non-coding rnas with associated co-expression and competing endogenous rna networks in the hippocampus of patients with alzheimer's disease. |
2021-12-03 |
2023-08-13 |
human |
| Xiaoqin Zhang, Xiaojie Wei, Yufei Mei, Dongpi Wang, Jing Wang, Yiping Zhang, Xuekun Li, Yan Gu, Guoping Peng, Binggui Su. Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease. Stem cell reports. 2021-12-03. PMID:34861165. |
new neurons are abnormal in the adult hippocampus of alzheimer's disease (ad) mouse models. |
2021-12-03 |
2023-08-13 |
mouse |
| Fatemeh Panahzadeh, Rahim Mirnasouri, Masoud Rahmat. Exercise and Syzygium aromaticum reverse memory deficits, apoptosis and mitochondrial dysfunction of the hippocampus in Alzheimer's disease. Journal of ethnopharmacology. 2021-12-02. PMID:34856360. |
exercise and syzygium aromaticum reverse memory deficits, apoptosis and mitochondrial dysfunction of the hippocampus in alzheimer's disease. |
2021-12-02 |
2023-08-13 |
Not clear |
| McKenna E Williams, Jeremy A Elman, Linda K McEvoy, Ole A Andreassen, Anders M Dale, Graham M L Eglit, Lisa T Eyler, Christine Fennema-Notestine, Carol E Franz, Nathan A Gillespie, Donald J Hagler, Sean N Hatton, Richard L Hauger, Amy J Jak, Mark W Logue, Michael J Lyons, Ruth E McKenzie, Michael C Neale, Matthew S Panizzon, Olivia K Puckett, Chandra A Reynolds, Mark Sanderson-Cimino, Rosemary Toomey, Xin M Tu, Nathan Whitsel, Hong Xian, William S Kreme. 12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56. Brain communications. vol 3. issue 3. 2021-11-30. PMID:34396116. |
neuroimaging signatures based on composite scores of cortical thickness and hippocampal volume predict progression from mild cognitive impairment to alzheimer's disease. |
2021-11-30 |
2023-08-13 |
Not clear |
| McKenna E Williams, Jeremy A Elman, Linda K McEvoy, Ole A Andreassen, Anders M Dale, Graham M L Eglit, Lisa T Eyler, Christine Fennema-Notestine, Carol E Franz, Nathan A Gillespie, Donald J Hagler, Sean N Hatton, Richard L Hauger, Amy J Jak, Mark W Logue, Michael J Lyons, Ruth E McKenzie, Michael C Neale, Matthew S Panizzon, Olivia K Puckett, Chandra A Reynolds, Mark Sanderson-Cimino, Rosemary Toomey, Xin M Tu, Nathan Whitsel, Hong Xian, William S Kreme. 12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56. Brain communications. vol 3. issue 3. 2021-11-30. PMID:34396116. |
we hypothesized that: (i) a validated mri-derived alzheimer's disease signature based on cortical thickness and hippocampal volume in cognitively normal middle-aged adults would predict progression to mild cognitive impairment; and (ii) a novel grey matter mean diffusivity signature would be a better predictor than the thickness/volume signature. |
2021-11-30 |
2023-08-13 |
Not clear |
| James R Bamburg, Laurie S Minamide, O'Neil Wiggan, Lubna H Tahtamouni, Thomas B Kuh. Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration. Cells. vol 10. issue 10. 2021-11-30. PMID:34685706. |
in ~20% of rodent hippocampal neurons, rods form more slowly in a receptor-mediated process triggered by factors intimately connected to disease-related dementias, e.g., amyloid-β in alzheimer's disease. |
2021-11-30 |
2023-08-13 |
Not clear |
| Karine Ramires Lima, Helen Lidiane Schmidt, Leticia Rossi Daré, Caroline Bitencourt Soares, Luiza Freitas Lopes, Felipe P Carpes, Pâmela Billig Mello-Carpe. Concurrent exercise does not prevent recognition memory deficits induced by beta-amyloid in rats. Physiology & behavior. vol 243. 2021-11-30. PMID:34715093. |
here we investigate the potential of concurrent exercise to prevent recognition memory deficits in an alzheimer's disease-like model induced by the hippocampal beta-amyloid (aβ) injection in wistar rats. |
2021-11-30 |
2023-08-13 |
rat |
| Sebastian B Arredondo, Daniel T Reyes, Andrea Herrera-Soto, Muriel D Mardones, Nibaldo C Inestrosa, Lorena Varela-Nalla. Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease. Scientific reports. vol 11. issue 1. 2021-11-30. PMID:34824314. |
andrographolide promotes hippocampal neurogenesis and spatial memory in the appswe/ps1Δe9 mouse model of alzheimer's disease. |
2021-11-30 |
2023-08-13 |
mouse |
| Deepika Shukla, Pravat K Mandal, Ritwick Mishra, Khushboo Punjabi, Divya Dwivedi, Manjari Tripathi, Vaishali Badhauti. Hippocampal Glutathione Depletion and pH Increment in Alzheimer's Disease: An in vivo MRS Study. Journal of Alzheimer's disease : JAD. vol 84. issue 3. 2021-11-29. PMID:34633325. |
hippocampal glutathione depletion and ph increment in alzheimer's disease: an in vivo mrs study. |
2021-11-29 |
2023-08-13 |
Not clear |
| Stephanie Langella, Peter J Mucha, Kelly S Giovanello, Eran Daya. The association between hippocampal volume and memory in pathological aging is mediated by functional redundancy. Neurobiology of aging. vol 108. 2021-11-28. PMID:34614422. |
hippocampal neurodegeneration, a primary component of alzheimer's disease pathology, relates to poor cognition; however, the mechanisms underlying this relationship are not well understood. |
2021-11-28 |
2023-08-13 |
human |
| Marina Eckermann, Bernhard Schmitzer, Franziska van der Meer, Jonas Franz, Ove Hansen, Christine Stadelmann, Tim Saldit. Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 48. 2021-11-25. PMID:34819378. |
we have studied the three-dimensional (3d) cytoarchitecture of the human hippocampus in neuropathologically healthy and alzheimer's disease (ad) individuals, based on phase-contrast x-ray computed tomography of postmortem human tissue punch biopsies. |
2021-11-25 |
2023-08-13 |
human |
| Gonzalo Forno, Albert Lladó, Michael Hornberge. Going round in circles-The Papez circuit in Alzheimer's disease. The European journal of neuroscience. vol 54. issue 10. 2021-11-24. PMID:34656073. |
the hippocampus is regarded as the pivotal structure for episodic memory symptoms associated with alzheimer's disease (ad) pathophysiology. |
2021-11-24 |
2023-08-13 |
Not clear |