| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Balaji Kannappan, Jan Te Nijenhuis, Yu Yong Choi, Jang Jae Lee, Kyu Yeong Choi, Irena Balzekas, Ho Yub Jung, Youngshik Choe, Min Kyung Song, Ji Yeon Chung, Jung-Min Ha, Seong-Min Choi, Hoowon Kim, Byeong C Kim, Hang Joon Jo, Kun Ho Le. Can hippocampal subfield measures supply information that could be used to improve the diagnosis of Alzheimer's disease? PloS one. vol 17. issue 11. 2022-11-03. PMID:36327265. |
can hippocampal subfield measures supply information that could be used to improve the diagnosis of alzheimer's disease? |
2022-11-03 |
2023-08-14 |
human |
| Balaji Kannappan, Jan Te Nijenhuis, Yu Yong Choi, Jang Jae Lee, Kyu Yeong Choi, Irena Balzekas, Ho Yub Jung, Youngshik Choe, Min Kyung Song, Ji Yeon Chung, Jung-Min Ha, Seong-Min Choi, Hoowon Kim, Byeong C Kim, Hang Joon Jo, Kun Ho Le. Can hippocampal subfield measures supply information that could be used to improve the diagnosis of Alzheimer's disease? PloS one. vol 17. issue 11. 2022-11-03. PMID:36327265. |
we conclude that the hippocampal subfield volumetric differences from structural imaging show promise for improving the diagnosis of alzheimer's disease. |
2022-11-03 |
2023-08-14 |
human |
| Mubeen A Ansari, Muddanna S Rao, Aishah Al-Jarallah, Fawzi M Babike. Early Time Course of Oxidative Stress in Hippocampal Synaptosomes and Cognitive Loss Following Impaired Insulin Signaling in Rats: Development of Sporadic Alzheimer's Disease. Brain research. 2022-11-03. PMID:36328067. |
early time course of oxidative stress in hippocampal synaptosomes and cognitive loss following impaired insulin signaling in rats: development of sporadic alzheimer's disease. |
2022-11-03 |
2023-08-14 |
rat |
| Hong-Yan Cai, Jing Qiao, Si-Ru Chen, Wei-Ping Fa. [Mitochondrial calcium uniporter knockdown in hippocampal neurons improved the learning and memory dysfunction of Alzheimer's disease mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 5. 2022-11-01. PMID:36319095. |
[mitochondrial calcium uniporter knockdown in hippocampal neurons improved the learning and memory dysfunction of alzheimer's disease mice]. |
2022-11-01 |
2023-08-14 |
mouse |
| Jenna N Adams, Soyun Kim, Batool Rizvi, Mithra Sathishkumar, Lisa Taylor, Alyssa L Harris, Abanoub Mikhail, David B Keator, Liv McMillan, Michael A Yass. Entorhinal-Hippocampal Circuit Integrity is Related to Mnemonic Discrimination and Amyloid-β Pathology in Older Adults. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-27. PMID:36302636. |
mnemonic discrimination, a cognitive process that relies on hippocampal pattern separation, is one of the first memory domains to decline in aging and preclinical alzheimer's disease. |
2022-10-27 |
2023-08-14 |
human |
| Gohar Karapetyan, Katarine Fereshetyan, Hayk Harutyunyan, Konstantin Yenkoya. The synergy of β amyloid 1-42 and oxidative stress in the development of Alzheimer's disease-like neurodegeneration of hippocampal cells. Scientific reports. vol 12. issue 1. 2022-10-26. PMID:36284177. |
the synergy of β amyloid 1-42 and oxidative stress in the development of alzheimer's disease-like neurodegeneration of hippocampal cells. |
2022-10-26 |
2023-08-14 |
rat |
| Julia J Segura-Uribe, Paola Garcia-de la Torre, Tzayaka Castillo-Mendieta, Iván Bribiesca-Cruz, Sandra Orozco-Suárez, Marvin Soriano-Ursúa, Rodolfo Pinto-Almazán, Claudia Fuentes-Venado, Christian Guerra-Araiz. Tibolone Improves Memory and Decreases the Content of Amyloid-β Peptides and Tau Protein in the Hippocampus of a Mice Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-10-24. PMID:36278346. |
tibolone improves memory and decreases the content of amyloid-β peptides and tau protein in the hippocampus of a mice model of alzheimer's disease. |
2022-10-24 |
2023-08-14 |
mouse |
| Ankur Kumar, Bhupender Nehra, Dilpreet Singh, Dileep Kuma, Pooja A Chawl. Recent advances in the development of nitrogen-containing heterocyclic Anti-Alzheimer's agents. Current topics in medicinal chemistry. 2022-10-24. PMID:36278462. |
alzheimer's disease is usually triggered by numerous associated factors, including depleted amount of acetylcholine (ach), excessive aggregation of β-amyloid peptide (aβ), tau hyperphosphorylation with neurofibrillary tangle formation as well as deposition of feeble plaques in a specific portion of the brain (hippocampus and cortex). |
2022-10-24 |
2023-08-14 |
Not clear |
| Marie-Ève Martineau-Dussault, Claire André, Véronique Daneault, Andrée-Ann Baril, Katia Gagnon, Hélène Blais, Dominique Petit, Jacques Y Montplaisir, Dominique Lorrain, Célyne Bastien, Carol Hudon, Maxime Descoteaux, Arnaud Boré, Guillaume Theaud, Cynthia Thompson, Julie Legault, Guillermo E Martinez Villar, Alexandre Lafrenière, Chantal Lafond, Danielle Gilbert, Julie Carrier, Nadia Gosseli. Medial temporal lobe and obstructive sleep apnea: Effect of sex, age, cognitive status and free-water. NeuroImage. Clinical. vol 36. 2022-10-22. PMID:36272339. |
medial temporal structures, namely the hippocampus, the entorhinal cortex and the parahippocampal gyrus, are particularly vulnerable to alzheimer's disease and hypoxemia. |
2022-10-22 |
2023-08-14 |
human |
| Jennyfer Tena, Izumi Maezawa, Mariana Barboza, Maurice Wong, Chenghao Zhu, Michael Russelle Alverez, Lee-Way Jin, Angela M Zivkovic, Carlito B Lebrill. Regio-Specific N-Glycome and N-Glycoproteome Map of the Elderly Human Brain with and without Alzheimer's Disease. Molecular & cellular proteomics : MCP. 2022-10-17. PMID:36252735. |
to obtain the broader representation of glycan compositions, four subjects with two in their seventies and two in their nineties representing two alzheimer disease subjects, one hippocampal sclerosis subject, and one subject with no cognitive impairment were analyzed. |
2022-10-17 |
2023-08-14 |
human |
| Hongyan Cai, Jing Qiao, Siru Chen, Junting Yang, Christian Hölscher, Zhaojun Wang, Jinshun Qi, Meina W. MCU knockdown in hippocampal neurons improves memory performance in an APP/PS1/tau transgenic mouse Alzheimer's disease model. Acta biochimica et biophysica Sinica. 2022-10-14. PMID:36239352. |
mcu knockdown in hippocampal neurons improves memory performance in an app/ps1/tau transgenic mouse alzheimer's disease model. |
2022-10-14 |
2023-08-14 |
mouse |
| Cintya Nirvana Dutta, Leonardo Christov-Moore, Hernando Ombao, Pamela K Dougla. Neuroprotection in late life attention-deficit/hyperactivity disorder: A review of pharmacotherapy and phenotype across the lifespan. Frontiers in human neuroscience. vol 16. 2022-10-13. PMID:36226261. |
crucially, these neuroprotective effects were significant in brain regions (e.g., hippocampus, amygdala) where severe volume loss is linked to cognitive impairment and alzheimer's disease. |
2022-10-13 |
2023-08-14 |
Not clear |
| Saeid Bagheri-Mohammadi, Sahar Askari, Behrang Alani, Maryam Moosavi, Rasoul Ghasem. Cinnamaldehyde Regulates Insulin and Caspase-3 Signaling Pathways in the Sporadic Alzheimer's Disease Model: Involvement of Hippocampal Function via IRS-1, Akt, and GSK-3β Phosphorylation. Journal of molecular neuroscience : MN. 2022-10-09. PMID:36210429. |
cinnamaldehyde regulates insulin and caspase-3 signaling pathways in the sporadic alzheimer's disease model: involvement of hippocampal function via irs-1, akt, and gsk-3β phosphorylation. |
2022-10-09 |
2023-08-14 |
rat |
| Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aun. Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. Brain communications. vol 4. issue 5. 2022-10-05. PMID:36196083. |
reduced rna adenosine-to-inosine editing in hippocampus vasculature associated with alzheimer's disease. |
2022-10-05 |
2023-08-14 |
Not clear |
| Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aun. Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. Brain communications. vol 4. issue 5. 2022-10-05. PMID:36196083. |
here, we investigated if changes in adenosine-to-inosine editing were associated with presence of alzheimer's disease in total prefrontal cortex, total hippocampus, cortex vasculature and hippocampus vasculature using available rna sequencing files. |
2022-10-05 |
2023-08-14 |
Not clear |
| Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aun. Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. Brain communications. vol 4. issue 5. 2022-10-05. PMID:36196083. |
we found modest and substantial loss of adenosine-to-inosine editing in hippocampus and hippocampus vasculature, respectively, in alzheimer's disease relative to normal cognition and increased expression of interferon and nuclear factor kappa b regulated genes in hippocampus. |
2022-10-05 |
2023-08-14 |
Not clear |
| Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aun. Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. Brain communications. vol 4. issue 5. 2022-10-05. PMID:36196083. |
unedited alu rnas as found in alzheimer's disease hippocampus vasculature were potent innate immune activators while edited alu rnas as found in normal cognition hippocampus vasculature were weak innate immune activators. |
2022-10-05 |
2023-08-14 |
Not clear |
| Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aun. Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. Brain communications. vol 4. issue 5. 2022-10-05. PMID:36196083. |
taken together, our results support a model whereby loss of alu rna adenosine-to-inosine editing in hippocampus results in innate immune activation that may contribute to alzheimer's disease pathogenesis. |
2022-10-05 |
2023-08-14 |
Not clear |
| Jiayuan Xu, Xianyou Xia, Qiaojun Li, Yan Dou, Xinjun Suo, Zuhao Sun, Nana Liu, Yating Han, Xiaodi Sun, Yukun He, Wen Qin, Shijie Zhang, Tobias Banaschewski, Herta Flor, Antoine Grigis, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Eric Artiges, Frauke Nees, Tomáš Paus, Luise Poustka, Sarah Hohmann, Henrik Walter, Pak Chung Sham, Gunter Schumann, Xudong Wu, Mulin Jun Li, Chunshui Y. A causal association of ANKRD37 with human hippocampal volume. Molecular psychiatry. 2022-10-04. PMID:36195640. |
the pairwise relationships of rs1053218 with hippocampal volume, rs1053218 with cg26741686 methylation, cg26741686 methylation with ankrd37 expression, and ankrd37 expression with hippocampal volume could be replicated in an independent healthy young (n = 443) dataset and observed in elderly people (n = 194), and were more significant in patients with late-onset alzheimer's disease (n = 76). |
2022-10-04 |
2023-08-14 |
mouse |
| Alissa M Butts, Mary M Machulda, Peter Martin, Scott A Przybelski, Joseph R Duffy, Jonathan Graff-Radford, David S Knopman, Ronald C Petersen, Clifford R Jack, Val J Lowe, Keith A Josephs, Jennifer L Whitwel. Temporal Cortical Thickness and Cognitive Associations among Typical and Atypical Phenotypes of Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 6. issue 1. 2022-10-03. PMID:36186727. |
the hippocampus and temporal lobe are atrophic in typical amnestic alzheimer's disease (tad) and are used as imaging biomarkers in treatment trials. |
2022-10-03 |
2023-08-14 |
Not clear |