| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuki Nakanishi, Kosuke Norimatsu, Akira Tani, Teruki Matsuoka, Ryoma Matsuzaki, Syogo Kakimoto, Nao Nojima, Yuta Tachibe, Yuki Kato, Masaki Inadome, Riho Kitazato, Shotaro Otsuka, Seiya Takada, Megumi Sumizono, Harutoshi Sakakim. Effects of early exercise intervention and exercise cessation on neuronal loss and neuroinflammation in a senescence-accelerated mouse prone 8. Neuroscience letters. 2023-05-14. PMID:37182575. |
physical exercise is beneficial for preventing alzheimer's disease (ad) and cognitive decline through several mechanisms, including suppression of neuroinflammation and neuronal loss in the hippocampus. |
2023-05-14 |
2023-08-14 |
mouse |
| Titis Nurmasitoh, Dwi Cahyani Ratna Sari, Rina Susilowat. Moderate-Intensity Intermittent Exercise Prevents Memory Deficit, Hippocampal Neuron Loss, and Elevated Level of Alzheimer's Dementia Markers in the Hippocampus of Trimethyltin-Induced Rats. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2023-05-14. PMID:37182815. |
moderate-intensity intermittent exercise prevents memory deficit, hippocampal neuron loss, and elevated level of alzheimer's dementia markers in the hippocampus of trimethyltin-induced rats. |
2023-05-14 |
2023-08-14 |
rat |
| Erica S Brady, Jessica Griffiths, Lilya Andrianova, Monika Bielska, Takashi Saito, Takaomi C Saido, Andrew D Randall, Francesco Tamagnini, Jonathan Witton, Michael T Crai. Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in App Neurobiology of disease. 2023-05-12. PMID:37172910. |
alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in app in the early stages of alzheimer's disease (ad), the accumulation of the peptide amyloid-β (aβ) damages synapses and disrupts neuronal activity, leading to the disruption of neuronal oscillations associated with cognition. |
2023-05-12 |
2023-08-14 |
mouse |
| Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K Gouras, Laurent Roybo. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies. Stem cell reports. vol 18. issue 5. 2023-05-10. PMID:37163981. |
human ipsc-derived hippocampal spheroids: an innovative tool for stratifying alzheimer disease patient-specific cellular phenotypes and developing therapies. |
2023-05-10 |
2023-08-14 |
human |
| Zhengwu Zhang, Yuexuan Wu, Di Xiong, Joseph G Ibrahim, Anuj Srivastava, Hongtu Zh. LESA: Longitudinal Elastic Shape Analysis of Brain Subcortical Structures. Journal of the American Statistical Association. vol 118. issue 541. 2023-05-09. PMID:37153845. |
in particular, with the alzheimer's disease neuroimaging initiative (adni) data, we found that the alzheimer's disease (ad) can significantly speed the shape change of ventricle and hippocampus from 60 to 75 years old compared with normal aging. |
2023-05-09 |
2023-08-14 |
human |
| Qiyao Wang, Chenglong Xia, An Zhu, Yongjie Bao, Jiani Lu, Yuan Chen, Jiayi Xu, Binbin Wang, C Benjamin Naman, Liping Li, Qinwen Wang, Hao Liu, Hongze Liang, Wei Cu. Discrepancy of synaptic and microtubular protein phosphorylation in the hippocampus of APP/PS1 and MAPT×P301S transgenic mice at the early stage of Alzheimer's disease. Metabolic brain disease. 2023-05-09. PMID:37160613. |
discrepancy of synaptic and microtubular protein phosphorylation in the hippocampus of app/ps1 and mapt×p301s transgenic mice at the early stage of alzheimer's disease. |
2023-05-09 |
2023-08-14 |
mouse |
| Teresa Juárez-Cedillo, Nancy Martínez-Rodríguez, José Manuel Fragoso, Valentin Islas-Pérez, Amara López-Martínez, Antonio Valle-Medin. Multifactor Dimensionality Reduction Analysis to Evaluate the Association of Dopamine Beta-Hydroxylase (DΒH) Polymorphisms with Susceptibility to Dementia (SADEM Study). Molecular neurobiology. 2023-05-06. PMID:37148523. |
since the activity of dopamine b hydroxylase (dβh) is reduced in the hippocampus and neocortex in the brain, changes in the physiological status of dopamine have been reported in alzheimer's disease (ad) induced by this enzyme. |
2023-05-06 |
2023-08-14 |
Not clear |
| Ye Ji Lee, Ye Ji Jeong, Eun Ji Kang, Beom Seok Kang, Song Hee Lee, You Jin Kim, Seong Su Kang, Sang Won Suh, Eun Hee Ah. GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression. Frontiers in molecular neuroscience. vol 16. 2023-05-05. PMID:37143467. |
gap-43 closely interacts with bdnf in hippocampal neurons and is associated with alzheimer's disease progression. |
2023-05-05 |
2023-08-14 |
Not clear |
| Pulak R Manna, Sudhir Kshirsagar, Jangampalli Adi Pradeepkiran, Priyanka Rawat, Subodh Kumar, Arubala P Reddy, P Hemachandra Redd. Protective function of StAR in amyloid-β accumulated hippocampal neurotoxicity and neurosteroidogenesis: Mechanistic insights into Alzheimer's disease. Biochimica et biophysica acta. Molecular basis of disease. 2023-05-04. PMID:37142132. |
protective function of star in amyloid-β accumulated hippocampal neurotoxicity and neurosteroidogenesis: mechanistic insights into alzheimer's disease. |
2023-05-04 |
2023-08-14 |
Not clear |
| Anchalee Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W Hu, Tewarit Sarachana, Tewin Tencomna. Transcriptomic analysis of glutamate-induced HT22 neurotoxicity as a model for screening anti-Alzheimer's drugs. Scientific reports. vol 13. issue 1. 2023-05-04. PMID:37142620. |
glutamate-induced neurotoxicity in the ht22 mouse hippocampal neuronal cell line has been recognized as a valuable cell model for the study of neurotoxicity associated with neurodegenerative diseases including alzheimer's disease (ad). |
2023-05-04 |
2023-08-14 |
mouse |
| Daniel Zvi Press, Christian Sandøe Musaeus, Li Zhao, Jocelyn Breton, Mouhsin M Shafi, Weiying Dai, David C Also. Levetiracetam Increases Hippocampal Blood Flow in Alzheimer's Disease as Measured by Arterial Spin Labelling MRI. Journal of Alzheimer's disease : JAD. 2023-05-01. PMID:37125545. |
levetiracetam increases hippocampal blood flow in alzheimer's disease as measured by arterial spin labelling mri. |
2023-05-01 |
2023-08-14 |
Not clear |
| Yu Chen, Hailin Yue, Hulin Kuang, Jianxin Wan. RBS-Net: Hippocampus segmentation using multi-layer feature learning with the region, boundary and structure loss. Computers in biology and medicine. vol 160. 2023-04-30. PMID:37120987. |
hippocampus has great influence over the alzheimer's disease (ad) research because of its essential role as a biomarker in the human brain. |
2023-04-30 |
2023-08-14 |
human |
| Mengjin Dong, Long Xie, Sandhitsu R Das, Jiancong Wang, Laura E M Wisse, Robin deFlores, David A Wolk, Paul A Yushkevic. Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI. ArXiv. 2023-04-24. PMID:37090239. |
longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as alzheimer's disease (ad). |
2023-04-24 |
2023-08-14 |
Not clear |
| Yaqiong Xiao, Liangjun Liao, Kaiyu Huang, Shun Yao, Lei Ga. Coupling Between Hippocampal Parenchymal Fraction and Cortical Grey Matter Atrophy at Different Stages of Cognitive Decline. Journal of Alzheimer's disease : JAD. 2023-04-24. PMID:37092228. |
hippocampal atrophy is a significant brain marker of pathology in alzheimer's disease (ad). |
2023-04-24 |
2023-08-14 |
Not clear |
| Ximeng Yang, Chihiro Tohd. Diosgenin restores memory function via SPARC-driven axonal growth from the hippocampus to the PFC in Alzheimer's disease model mice. Molecular psychiatry. 2023-04-21. PMID:37085711. |
diosgenin restores memory function via sparc-driven axonal growth from the hippocampus to the pfc in alzheimer's disease model mice. |
2023-04-21 |
2023-08-14 |
mouse |
| Nazia Siddiqui, Javed Ali, Suhel Parvez, Abul Kalam Najmi, Mohd Akhta. Neuroprotective Role of DPP-4 Inhibitor Linagliptin Against Neurodegeneration, Neuronal Insulin Resistance and Neuroinflammation Induced by Intracerebroventricular Streptozotocin in Rat Model of Alzheimer's Disease. Neurochemical research. 2023-04-20. PMID:37079222. |
alzheimer's disease (ad) is an age-related, multifactorial progressive neurodegenerative disorder manifested by cognitive impairment and neuronal death in the brain areas like hippocampus, yet the precise neuropathology of ad is still unclear. |
2023-04-20 |
2023-08-14 |
rat |
| Sha Sha, Thomas Chaigneau, Slavica Kranti. Pre-symptomatic synaptic dysfunction and longitudinal decay of hippocampal synaptic function in APPPS1 mouse model of Alzheimer's disease is sex-independent. Brain research bulletin. 2023-04-20. PMID:37080395. |
pre-symptomatic synaptic dysfunction and longitudinal decay of hippocampal synaptic function in appps1 mouse model of alzheimer's disease is sex-independent. |
2023-04-20 |
2023-08-14 |
mouse |
| Avital Licht-Murava, Samantha M Meadows, Fernando Palaguachi, Soomin C Song, Stephanie Jackvony, Yaron Bram, Constance Zhou, Robert E Schwartz, Robert C Froemke, Adam L Orr, Anna G Or. Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Science advances. vol 9. issue 16. 2023-04-19. PMID:37075107. |
we found that patients with alzheimer's disease or frontotemporal dementia have aberrant tdp-43 accumulation in hippocampal astrocytes. |
2023-04-19 |
2023-08-14 |
mouse |
| Juri-Alexander Witt, Albert J Becker, Christoph Helmstaedte. The multifactorial etiology of cognitive deficits in epilepsy and the neuropathology of mesial temporal lobe epilepsy beyond hyperphosphorylated tau. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-18. PMID:37070290. |
in response to the recent review by zawar and kapur on the overlap between mesial temporal lobe epilepsy (mtle) and alzheimer's disease (ad), we (1) underscore that the bidirectionality between epilepsy and dementia is of high interest, also from the epileptological perspective; (2) outline the multifactorial etiology of cognitive deficits in epilepsy; (3) emphasize that the most prevalent neuropathological findings in mtle comprise hippocampal sclerosis, dysplastic lesions, and neurodevelopmental neoplasm; and (4) state that anti-seizure medication can also have adverse effects on cognition. |
2023-04-18 |
2023-08-14 |
Not clear |
| Aaron J Gorelik, Sarah E Paul, Nicole R Karcher, Emma C Johnson, Isha Nagella, Lauren Blaydon, Hailey Modi, Isabella S Hansen, Sarah M C Colbert, David A A Baranger, Sara A Norton, Isaiah Spears, Brian Gordon, Wei Zhang, Patrick L Hill, Thomas F Oltmanns, Janine D Bijsterbosch, Arpana Agrawal, Alexander S Hatoum, Ryan Bogda. A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study. Behavior genetics. 2023-04-18. PMID:37071275. |
genetic risk for late onset alzheimer disease (ad) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. |
2023-04-18 |
2023-08-14 |
Not clear |