| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anders M Fjell, Linda McEvoy, Dominic Holland, Anders M Dale, Kristine B Walhov. What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus. Progress in neurobiology. vol 117. 2014-12-23. PMID:24548606. |
effects of aging, amyloid and alzheimer's disease on the cerebral cortex and the hippocampus. |
2014-12-23 |
2023-08-12 |
Not clear |
| Hui-li Liu, Gang Zhao, He Zhang, Li-de Sh. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice. Behavioural brain research. vol 256. 2014-12-18. PMID:23968591. |
long-term treadmill exercise inhibits the progression of alzheimer's disease-like neuropathology in the hippocampus of app/ps1 transgenic mice. |
2014-12-18 |
2023-08-12 |
mouse |
| Hui-li Liu, Gang Zhao, He Zhang, Li-de Sh. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice. Behavioural brain research. vol 256. 2014-12-18. PMID:23968591. |
the present study was undertaken to further investigate whether the treadmill running could inhibit the progression of alzheimer's disease (ad)-like neuropathology in hippocampus of the app/ps1 mouse models of ad, and to define a potential molecular mechanism underlying the exercise-induced reduction in ad-like neuropathology. |
2014-12-18 |
2023-08-12 |
mouse |
| Emma R Mulder, Remko A de Jong, Dirk L Knol, Ronald A van Schijndel, Keith S Cover, Pieter J Visser, Frederik Barkhof, Hugo Vrenke. Hippocampal volume change measurement: quantitative assessment of the reproducibility of expert manual outlining and the automated methods FreeSurfer and FIRST. NeuroImage. vol 92. 2014-12-18. PMID:24521851. |
to measure hippocampal volume change in alzheimer's disease (ad) or mild cognitive impairment (mci), expert manual delineation is often used because of its supposed accuracy. |
2014-12-18 |
2023-08-12 |
Not clear |
| Eric C Miller, Peter J Teravskis, Benjamin W Dummer, Xiaohui Zhao, Richard L Huganir, Dezhi Lia. Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits. The European journal of neuroscience. vol 39. issue 7. 2014-12-18. PMID:24713000. |
here, we show that tau mislocalizes to dendritic spines in cultured hippocampal neurons from appswe alzheimer's disease (ad)-transgenic mice and in cultured rat hippocampal neurons treated with soluble aβ oligomers. |
2014-12-18 |
2023-08-13 |
mouse |
| Efrat Kravitz, Inna Gaisler-Salomon, Anat Biego. Hippocampal glutamate NMDA receptor loss tracks progression in Alzheimer's disease: quantitative autoradiography in postmortem human brain. PloS one. vol 8. issue 11. 2014-12-17. PMID:24312282. |
hippocampal glutamate nmda receptor loss tracks progression in alzheimer's disease: quantitative autoradiography in postmortem human brain. |
2014-12-17 |
2023-08-12 |
human |
| Efrat Kravitz, Inna Gaisler-Salomon, Anat Biego. Hippocampal glutamate NMDA receptor loss tracks progression in Alzheimer's disease: quantitative autoradiography in postmortem human brain. PloS one. vol 8. issue 11. 2014-12-17. PMID:24312282. |
early alzheimer's disease (ad) is characterized by memory loss and hippocampal atrophy with relative sparing of basal ganglia. |
2014-12-17 |
2023-08-12 |
human |
| Sandra I Mota, Ildete L Ferreira, Jorge Valero, Elisabete Ferreiro, Ana L Carvalho, Catarina R Oliveira, A Cristina Reg. Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway. Experimental neurology. vol 261. 2014-12-17. PMID:25128699. |
impaired src signaling and post-synaptic actin polymerization in alzheimer's disease mice hippocampus--linking nmda receptors and the reelin pathway. |
2014-12-17 |
2023-08-13 |
mouse |
| Kazuya Fukumoto, Hiroyuki Mizoguchi, Hideyuki Takeuchi, Hiroshi Horiuchi, Jun Kawanokuchi, Shijie Jin, Tetsuya Mizuno, Akio Suzumur. Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment. Behavioural brain research. vol 268. 2014-12-16. PMID:24713151. |
amyloid β, a neurotoxic protein, causes disruption of hippocampal synaptic plasticity, and induces cognitive impairment in alzheimer's disease. |
2014-12-16 |
2023-08-13 |
mouse |
| Pierre Lavenex, Pamela Banta Lavenex, Grégoire Favr. What animals can teach clinicians about the hippocampus. Frontiers of neurology and neuroscience. vol 34. 2014-12-16. PMID:24777129. |
abnormalities in hippocampal structure and function have been reported in a number of human neuropathological and neurodevelopmental disorders, including alzheimer's disease, autism spectrum disorders, down syndrome, epilepsy, and schizophrenia. |
2014-12-16 |
2023-08-13 |
human |
| Frauke Nees, Sebastian T Pohlac. Functional MRI studies of the hippocampus. Frontiers of neurology and neuroscience. vol 34. 2014-12-16. PMID:24777133. |
besides the importance of such studies for basic research, the investigation of hippocampal (dys)function has clinical relevance for diseases ranging from neurological disorders such as alzheimer's disease or epilepsy to mental disorders such as schizophrenia or anxiety disorders. |
2014-12-16 |
2023-08-13 |
human |
| K K Moodley, D Cha. The hippocampus in neurodegenerative disease. Frontiers of neurology and neuroscience. vol 34. 2014-12-16. PMID:24777134. |
neurodegenerative changes within the hippocampus and an extended neuronal network involving the medial temporal and medial parietal lobe result in the archetypal memory impairment seen in alzheimer's disease (ad). |
2014-12-16 |
2023-08-13 |
Not clear |
| Rasoul Ghasemi, Asadollah Zarifkar, Karim Rastegar, Nader Maghsoudi, Maryam Moosav. Repeated intra-hippocampal injection of beta-amyloid 25–35 induces a reproducible impairment of learning and memory: considering caspase-3 and MAPKs activity. European journal of pharmacology. vol 726. 2014-12-15. PMID:24418687. |
alzheimer disease (ad) is characterized by accumulation of beta amyloid (aβ) and neuronal loss, particularly in the hippocampus. |
2014-12-15 |
2023-08-12 |
rat |
| Alison Burggren, Jesse Brow. Imaging markers of structural and functional brain changes that precede cognitive symptoms in risk for Alzheimer's disease. Brain imaging and behavior. vol 8. issue 2. 2014-12-12. PMID:24317680. |
neuroimaging has rapidly advanced investigations into dysfunction both within and emanating from the hippocampus in early alzheimer's disease . |
2014-12-12 |
2023-08-12 |
human |
| Yongfu Hao, Tianyao Wang, Xinqing Zhang, Yunyun Duan, Chunshui Yu, Tianzi Jiang, Yong Fa. Local label learning (LLL) for subcortical structure segmentation: application to hippocampus segmentation. Human brain mapping. vol 35. issue 6. 2014-12-09. PMID:24151008. |
volumetric analysis has also demonstrated the capability of our method in detecting hippocampal volume changes due to alzheimer's disease. |
2014-12-09 |
2023-08-12 |
Not clear |
| J Kuchling, T Sinnecker, I Bozin, J Dörr, V I Madai, J Sobesky, T Niendorf, F Paul, J Wuerfe. [Ultrahigh field MRI in context of neurological diseases]. Der Nervenarzt. vol 85. issue 4. 2014-12-08. PMID:24549692. |
detailed imaging of the hippocampus in alzheimer's disease and the substantia nigra in parkinson's disease as well as sensitivity to iron depositions could be valuable in neurodegenerative diseases. |
2014-12-08 |
2023-08-12 |
Not clear |
| Inna Gaisler-Salomon, Efrat Kravitz, Yulia Feiler, Michal Safran, Anat Biegon, Ninette Amariglio, Gideon Rechav. Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease. Neurobiology of aging. vol 35. issue 8. 2014-12-08. PMID:24679603. |
we studied hippocampus and caudate samples from alzheimer's disease (ad) patients and age-matched healthy controls, using direct sequencing and a high accuracy primer-extension technique to assess rna editing at the q/r glua2 site. |
2014-12-08 |
2023-08-12 |
Not clear |
| Hervé Maurin, Seon-Ah Chong, Igor Kraev, Heather Davies, Anna Kremer, Claire Marie Seymour, Benoit Lechat, Tomasz Jaworski, Peter Borghgraef, Herman Devijver, Geert Callewaert, Michael G Stewart, Fred Van Leuve. Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy. PloS one. vol 9. issue 2. 2014-12-03. PMID:24498342. |
the stratum lacunosum moleculare (slm) is the connection hub between entorhinal cortex and hippocampus, two brain regions that are most vulnerable in alzheimer's disease. |
2014-12-03 |
2023-08-12 |
mouse |
| Tomohiro Chiba, Laura Mack, Natalia Delis, Boris Brill, Bernd Grone. Stat3 inhibition in neural lineage cells. Hormone molecular biology and clinical investigation. vol 10. issue 2. 2014-12-03. PMID:25436682. |
abstract deregulation of signal transducer and activator of transcription 3 (stat3) is attracting attentions in neurological disorders of elderly populations, e.g., stat3 is inactivated in hippocampal neurons of alzheimer's disease (ad) brains, whereas it is often constitutively activated in glioblastoma multiforme (gbm), correlating with poor prognosis. |
2014-12-03 |
2023-08-13 |
mouse |
| Irene Epifanio, Noelia Ventura-Campo. Hippocampal shape analysis in Alzheimer's disease using functional data analysis. Statistics in medicine. vol 33. issue 5. 2014-12-01. PMID:24105806. |
hippocampal shape analysis in alzheimer's disease using functional data analysis. |
2014-12-01 |
2023-08-12 |
human |