| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kirsty Hamilton, Kate Morrow, Ermione Markantoni, Jenni Harve. Leptin prevents aberrant targeting of tau to hippocampal synapses via PI 3 kinase driven inhibition of GSK3β. Journal of neurochemistry. 2023-10-12. PMID:37822142. |
amyloid-β (aβ) and hyper-phosphorylated tau are key hallmarks of alzheimer's disease (ad), with an accumulation of both proteins linked to hippocampal synaptic dysfunction. |
2023-10-12 |
2023-10-15 |
Not clear |
| Hui Xue, Xiaojun Xu, Zhihan Yan, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Guangbin Cui, Quan Zhang, Shijun Qiu, Zhenwei Yao, Wen Qin, Feng Liu, Meng Liang, Jilian Fu, Qiang Xu, Jiayuan Xu, Yingying Xie, Peng Zhang, Wei Li, Caihong Wang, Wen Shen, Xiaochu Zhang, Kai Xu, Xi-Nian Zuo, Zhaoxiang Ye, Yongqiang Yu, Junfang Xian, Chunshui Y. Genome-wide association study of hippocampal blood-oxygen-level-dependent-cerebral blood flow correlation in Chinese Han population. iScience. vol 26. issue 10. 2023-10-12. PMID:37822511. |
the hippocampal bold-cbf correlation had an estimated heritability of 16.2-23.9% and showed reliable genome-wide significant association with a locus at 3q28, in which many variants have been linked to neuroimaging and cerebrospinal fluid markers of alzheimer's disease. |
2023-10-12 |
2023-10-15 |
human |
| Yi-Ju Lee, Sin-Rong Chen, Ping-En Ko, Mon-Yuan Yang, Meng-Hsuin Yu, Chau-Jong Wang, Huei-Jane Le. Quercetin-3-O-β-d-glucuronide in the Nuciferine Leaf Polyphenol Extract Promotes Neurogenesis Involving the Upregulation of the Tropomyosin Receptor Kinase (Trk) Receptor and AKT/Phosphoinositide 3-Kinase Signaling Pathway. Journal of agricultural and food chemistry. 2023-10-11. PMID:37819167. |
the impairment of hippocampal neurogenesis in adults may lead to neurodegenerative disease, such as alzheimer's disease. |
2023-10-11 |
2023-10-15 |
human |
| Zan Zhou, Wen-Jun Jiang, Li Li, Jun-Qiang S. Noise exposure increase apoptosis in the hippocampus of AD mice through the upregulation of CTSS. Biochemical and biophysical research communications. vol 681. 2023-10-06. PMID:37801777. |
however, the detrimental impact of noise exposure on alzheimer's disease (ad) animal models might be considerably greater than on ordinary model mice, yet the mechanisms by which noise exposure affects the hippocampus in these models have been scarcely investigated. |
2023-10-06 |
2023-10-15 |
mouse |
| Xi Liu, Hongming Li, Yong Fa. Predicting Alzheimer's Disease and Quantifying Asymmetric Degeneration of the Hippocampus Using Deep Learning of Magnetic Resonance Imaging Data. Proceedings. IEEE International Symposium on Biomedical Imaging. vol 2023. 2023-10-04. PMID:37790879. |
predicting alzheimer's disease and quantifying asymmetric degeneration of the hippocampus using deep learning of magnetic resonance imaging data. |
2023-10-04 |
2023-10-07 |
human |
| Xi Liu, Hongming Li, Yong Fa. Predicting Alzheimer's Disease and Quantifying Asymmetric Degeneration of the Hippocampus Using Deep Learning of Magnetic Resonance Imaging Data. Proceedings. IEEE International Symposium on Biomedical Imaging. vol 2023. 2023-10-04. PMID:37790879. |
in order to quantify lateral asymmetric degeneration of the hippocampus for early predicting alzheimer's disease (ad), we develop a deep learning (dl) model to learn informative features from the hippocampal magnetic resonance imaging (mri) data for predicting ad conversion in a time-to-event prediction modeling framework. |
2023-10-04 |
2023-10-07 |
human |
| Rohit Malik, Sunishtha Kalra, Pooja, Govind Singh, Meenu, Vinod Gahlot, Anjali Kajal, Rimp. Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent. Brain research. 2023-10-04. PMID:37793605. |
overcome scopolamine-induced alzheimer's type dementia in mice by activating the cholinergic system, anti-oxidant and protection of neuronal death in the brain (hippocampus region). |
2023-10-04 |
2023-10-07 |
mouse |
| Amin Firoozi, Aliakbar Alizadeh, Asadollah Zarifkar, Tahereh Esmaeilpour, Mohammad Reza Namavar, Omid Alavi, Farzaneh Dehghan. Comparison of the efficacy of human umbilical cord mesenchymal stem cells conditioned medium and platelet-rich plasma on the hippocampus of STZ-induced rat model of Alzheimer's disease: A behavioral and stereological study. IBRO neuroscience reports. vol 15. 2023-10-02. PMID:37780033. |
comparison of the efficacy of human umbilical cord mesenchymal stem cells conditioned medium and platelet-rich plasma on the hippocampus of stz-induced rat model of alzheimer's disease: a behavioral and stereological study. |
2023-10-02 |
2023-10-07 |
human |
| Jean Ikanga, Sabrina Hickle, Megan Schwinne, Emmanuel Epenge, Guy Gikelekele, Immaculee Kavugho, Nathan Tsengele, Mampunza Samuel, Liping Zhao, Deqiang Qiu, Anthony Stringer, Amit M Saindane, Alvaro Alonso, Daniel L Dran. Association Between Hippocampal Volume and African Neuropsychology Memory Tests in Adult Individuals with Probable Alzheimer's Disease in Democratic Republic of Congo. Journal of Alzheimer's disease : JAD. 2023-10-02. PMID:37781799. |
association between hippocampal volume and african neuropsychology memory tests in adult individuals with probable alzheimer's disease in democratic republic of congo. |
2023-10-02 |
2023-10-07 |
Not clear |
| Jean Ikanga, Sabrina Hickle, Megan Schwinne, Emmanuel Epenge, Guy Gikelekele, Immaculee Kavugho, Nathan Tsengele, Mampunza Samuel, Liping Zhao, Deqiang Qiu, Anthony Stringer, Amit M Saindane, Alvaro Alonso, Daniel L Dran. Association Between Hippocampal Volume and African Neuropsychology Memory Tests in Adult Individuals with Probable Alzheimer's Disease in Democratic Republic of Congo. Journal of Alzheimer's disease : JAD. 2023-10-02. PMID:37781799. |
western studies indicate potential associations between hippocampal volume and memory in the trajectory of alzheimer's disease (ad). |
2023-10-02 |
2023-10-07 |
Not clear |
| Jamie M Walker, Miranda E Orr, Timothy C Orr, Emma L Thorn, Thomas D Christie, Raquel T Yokoda, Meenakshi Vij, Alexander J Ehrenberg, Gabriel A Marx, Andrew T McKenzie, Justin Kauffman, Enna Selmanovic, Thomas Wisniewski, Eleanor Drummond, Charles L White, John F Crary, Kurt Farrell, Tiffany F Kautz, Elena V Daoud, Timothy E Richardso. Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-10-01. PMID:37777848. |
spatial proteomics of hippocampal subfield-specific pathology in alzheimer's disease and primary age-related tauopathy. |
2023-10-01 |
2023-10-07 |
Not clear |
| Jamie M Walker, Miranda E Orr, Timothy C Orr, Emma L Thorn, Thomas D Christie, Raquel T Yokoda, Meenakshi Vij, Alexander J Ehrenberg, Gabriel A Marx, Andrew T McKenzie, Justin Kauffman, Enna Selmanovic, Thomas Wisniewski, Eleanor Drummond, Charles L White, John F Crary, Kurt Farrell, Tiffany F Kautz, Elena V Daoud, Timothy E Richardso. Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-10-01. PMID:37777848. |
alzheimer's disease (ad) and primary age-related tauopathy (part) both harbor 3r/4r hyperphosphorylated-tau (p-tau)-positive neurofibrillary tangles (nfts) but differ in the spatial p-tau development in the hippocampus. |
2023-10-01 |
2023-10-07 |
Not clear |
| Meixiang Huang, Carolyn Tallon, Xiaolei Zhu, Kaitlyn D J Huizar, Silvia Picciolini, Ajit G Thomas, Lukas Tenora, Wathsala Liyanage, Francesca Rodà, Alice Gualerzi, Rangaramanujam M Kannan, Marzia Bedoni, Rana Rais, Barbara S Slushe. Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice. Pharmaceutics. vol 15. issue 9. 2023-09-28. PMID:37765332. |
the progression of alzheimer's disease (ad) correlates with the propagation of hyperphosphorylated tau (ptau) from the entorhinal cortex to the hippocampus and neocortex. |
2023-09-28 |
2023-10-07 |
mouse |
| Anna Papazoglou, Christina Henseler, Sandra Weickhardt, Johanna Daubner, Teresa Schiffer, Karl Broich, Jürgen Hescheler, Dan Ehninger, Catharina Scholl, Britta Haenisch, Agapios Sachinidis, Marco Weiergräbe. Whole genome transcriptome data from the WT cortex and hippocampus of female and male control and APP/PS1 Alzheimer's disease mice. Data in brief. vol 50. 2023-09-28. PMID:37767130. |
whole genome transcriptome data from the wt cortex and hippocampus of female and male control and app/ps1 alzheimer's disease mice. |
2023-09-28 |
2023-10-07 |
mouse |
| Stanislau Hrybouski, Sandhitsu R Das, Long Xie, Laura E M Wisse, Melissa Kelley, Jacqueline Lane, Monica Sherin, Michael DiCalogero, Ilya Nasrallah, John Detre, Paul A Yushkevich, David A Wol. Aging and Alzheimer's disease have dissociable effects on local and regional medial temporal lobe connectivity. Brain communications. vol 5. issue 5. 2023-09-28. PMID:37767219. |
instead, patients with symptomatic alzheimer's disease displayed reduced hippocampal connectivity within the medial temporal lobe as well as hypoconnectivity within the posterior-medial system. |
2023-09-28 |
2023-10-07 |
Not clear |
| Jinhuan Zhang, Linlin Xie, Changjiang Cheng, Yongfeng Liu, Xiaodong Zhang, Haoyu Wang, Jingting Hu, Haibo Yu, Jinping X. Hippocampal subfield volumes in mild cognitive impairment and alzheimer's disease: a systematic review and meta-analysis. Brain imaging and behavior. 2023-09-28. PMID:37768441. |
hippocampal subfield volumes in mild cognitive impairment and alzheimer's disease: a systematic review and meta-analysis. |
2023-09-28 |
2023-10-07 |
Not clear |
| Jinhuan Zhang, Linlin Xie, Changjiang Cheng, Yongfeng Liu, Xiaodong Zhang, Haoyu Wang, Jingting Hu, Haibo Yu, Jinping X. Hippocampal subfield volumes in mild cognitive impairment and alzheimer's disease: a systematic review and meta-analysis. Brain imaging and behavior. 2023-09-28. PMID:37768441. |
although numerous studies have been performed to explore hippocampal atrophy at the sub-regional level in mild cognitive impairment (mci) and alzheimer's disease (ad), the results have been inconsistent especially for whether and which subfields can be served as the most potential biomarkers in mci and ad. |
2023-09-28 |
2023-10-07 |
Not clear |
| Sarah E Heuer, Kelly J Keezer, Amanda A Hewes, Kristen D Onos, Kourtney C Graham, Gareth R Howell, Erik B Blos. Control of hippocampal synaptic plasticity by microglia-dendrite interactions depends on genetic context in mouse models of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-09-27. PMID:37753835. |
control of hippocampal synaptic plasticity by microglia-dendrite interactions depends on genetic context in mouse models of alzheimer's disease. |
2023-09-27 |
2023-10-07 |
mouse |
| Genevieve L Stein-O'Brien, Ryan Palaganas, Ernest M Meyer, Javier Redding-Ochoa, Olga Pletnikova, Haidan Guo, William R Bell, Juan C Troncoso, Richard L Huganir, Meaghan Morri. Transcriptional Signatures of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer's Disease. medRxiv : the preprint server for health sciences. 2023-09-25. PMID:37745408. |
transcriptional signatures of hippocampal tau pathology in primary age-related tauopathy and alzheimer's disease. |
2023-09-25 |
2023-10-07 |
Not clear |
| Jia Wang, Fang Zhou, Chang-E Xiong, Gui-Ping Wang, Lin-Wanyue Chen, Yu-Tong Zhang, Shi-Ge Qi, Zhi-Hui Wang, Can Mei, Yu-Jia Xu, Jian-Bo Zhan, Jing Chen. Serum sirtuin1: a potential blood biomarker for early diagnosis of Alzheimer's disease. Aging. vol 15. 2023-09-24. PMID:37742223. |
sirtuin 1, a nicotinamide adenine dinucleotide-dependent deacetylase that is highly expressed in the hippocampus and anterior cortex tissues related to alzheimer's disease pathology, can cross the blood-brain barrier and is a promising biomarker. |
2023-09-24 |
2023-10-07 |
Not clear |