| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Regina Biasibetti, João Paulo Almeida Dos Santos, Letícia Rodrigues, Krista Minéia Wartchow, Lucas Zingano Suardi, Patrícia Nardin, Nicholas Guerini Selistre, Dandara Vázquez, Carlos-Alberto Gonçalve. Hippocampal changes in STZ-model of Alzheimer's disease are dependent on sex. Behavioural brain research. vol 316. 2017-11-24. PMID:27585561. |
hippocampal changes in stz-model of alzheimer's disease are dependent on sex. |
2017-11-24 |
2023-08-13 |
rat |
| Hongyu Pan, Dongpi Wang, Xiaoqin Zhang, Dongming Zhou, Heng Zhang, Qi Qian, Xiao He, Zhaoling Liu, Yunjin Liu, Tingting Zheng, Ling Zhang, Mingkai Wang, Binggui Su. Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein. Stem cell reports. vol 7. issue 4. 2017-11-21. PMID:27693425. |
adult hippocampal neurogenesis was impaired in several alzheimer's disease models overexpressing mutant human amyloid precursor protein (happ). |
2017-11-21 |
2023-08-13 |
mouse |
| Yang Shen, Min Tian, Yuqiong Zheng, Fei Gong, Amy K Y Fu, Nancy Y I. Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer's Disease Model. Cell reports. vol 17. issue 7. 2017-11-20. PMID:27829153. |
stimulation of the hippocampal pomc/mc4r circuit alleviates synaptic plasticity impairment in an alzheimer's disease model. |
2017-11-20 |
2023-08-13 |
mouse |
| Yang Shen, Min Tian, Yuqiong Zheng, Fei Gong, Amy K Y Fu, Nancy Y I. Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer's Disease Model. Cell reports. vol 17. issue 7. 2017-11-20. PMID:27829153. |
hippocampal synaptic plasticity is modulated by neuropeptides, the disruption of which might contribute to cognitive deficits observed in alzheimer's disease (ad). |
2017-11-20 |
2023-08-13 |
mouse |
| Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Pooja Suri, Samuel G Mackintosh, Alan J Tackett, Dennis H Sullivan, Robert J Shmookler Reis, Richard A Denni. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Aging. vol 8. issue 12. 2017-11-20. PMID:27992858. |
proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in protein aggregation increases with age in normal tissues, and with pathology and age in alzheimer's hippocampus and mouse cardiac muscle. |
2017-11-20 |
2023-08-13 |
mouse |
| Rui Hu, Pan Wei, Lu Jin, Teng Zheng, Wen-Yu Chen, Xiao-Ya Liu, Xiao-Dong Shi, Jing-Ru Hao, Nan Sun, Can Ga. Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model. Cell death & disease. vol 8. issue 3. 2017-11-20. PMID:28358367. |
overexpression of ephb2 in hippocampus rescues impaired nmda receptors trafficking and cognitive dysfunction in alzheimer model. |
2017-11-20 |
2023-08-13 |
mouse |
| Tammy T Tran, Caroline L Speck, Aparna Pisupati, Michela Gallagher, Arnold Bakke. Increased hippocampal activation in ApoE-4 carriers and non-carriers with amnestic mild cognitive impairment. NeuroImage. Clinical. vol 13. 2017-11-17. PMID:28070483. |
increased fmri activation in the hippocampus is recognized as a signature characteristic of the amnestic mild cognitive impairment (amci) stage of alzheimer's disease (ad). |
2017-11-17 |
2023-08-13 |
human |
| Lauge Sørensen, Christian Igel, Akshay Pai, Ioana Balas, Cecilie Anker, Martin Lillholm, Mads Nielse. Differential diagnosis of mild cognitive impairment and Alzheimer's disease using structural MRI cortical thickness, hippocampal shape, hippocampal texture, and volumetry. NeuroImage. Clinical. vol 13. 2017-11-17. PMID:28119818. |
differential diagnosis of mild cognitive impairment and alzheimer's disease using structural mri cortical thickness, hippocampal shape, hippocampal texture, and volumetry. |
2017-11-17 |
2023-08-13 |
human |
| Felix-Martin Werner, Rafael Covena. Serotonergic Drugs: Agonists/Antagonists at Specific Serotonergic Subreceptors for the Treatment of Cognitive, Depressant and Psychotic Symptoms in Alzheimer's Disease. Current pharmaceutical design. vol 22. issue 14. 2017-11-16. PMID:26818863. |
alzheimer's disease is a neurodegenerative disease showing alterations in classical neurotransmitters, above all in the hippocampus and prefrontal/temporal cortices. |
2017-11-16 |
2023-08-13 |
Not clear |
| Morten Skøtt Thomsen, Jesper Tobias Andreasen, Maria Arvaniti, Kristi Anne Kohlmeie. Nicotinic Acetylcholine Receptors in the Pathophysiology of Al zheimer's Disease: The Role of Protein-Protein Interactions in Current and Future Treatment. Current pharmaceutical design. vol 22. issue 14. 2017-11-16. PMID:26818866. |
nicotinic acetylcholine receptors (nachrs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in alzheimer's disease (ad) due to their positioning within regions of the brain critical in learning and memory, such as the prefrontal cortex and hippocampus, and their demonstrated role in processes underlying cognition such as synaptic facilitation, and theta and gamma wave activity. |
2017-11-16 |
2023-08-13 |
Not clear |
| Jesper Hagemeier, Matthew R Woodward, Usama A Rafique, Chaitanya V Amrutkar, Niels Bergsland, Michael G Dwyer, Ralph Benedict, Robert Zivadinov, Kinga Sziget. Odor identification deficit in mild cognitive impairment and Alzheimer's disease is associated with hippocampal and deep gray matter atrophy. Psychiatry research. Neuroimaging. vol 255. 2017-11-16. PMID:27567325. |
odor identification deficit in mild cognitive impairment and alzheimer's disease is associated with hippocampal and deep gray matter atrophy. |
2017-11-16 |
2023-08-13 |
human |
| Ane-Victoria Idland, Roser Sala-Llonch, Tom Borza, Leiv Otto Watne, Torgeir Bruun Wyller, Anne Brækhus, Henrik Zetterberg, Kaj Blennow, Kristine Beate Walhovd, Anders Martin Fjel. CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults. Neurobiology of aging. vol 49. 2017-11-16. PMID:27794264. |
we tested whether csf nfl levels predict hippocampal atrophy rate in cognitively healthy older adults independently of the established csf alzheimer's disease (ad) biomarkers, β-amyloid 1-42, and phosphorylated tau (p-tau). |
2017-11-16 |
2023-08-13 |
human |
| Rebecca P Haberman, Ming Teng Koh, Michela Gallaghe. Heightened cortical excitability in aged rodents with memory impairment. Neurobiology of aging. vol 54. 2017-11-16. PMID:28104309. |
elevated excitability in the hippocampus has emerged as a key contributor to reduced memory function in aging and in cognitive impairment prodromal to alzheimer's disease. |
2017-11-16 |
2023-08-13 |
rat |
| Rebecca P Haberman, Ming Teng Koh, Michela Gallaghe. Heightened cortical excitability in aged rodents with memory impairment. Neurobiology of aging. vol 54. 2017-11-16. PMID:28104309. |
elevated neural excitability extending beyond the hippocampus to interconnected posterior cortex (retrosplenial/parietal) was reduced by treatment with levetiracetam, a therapeutic with behavioral efficacy that has previously translated from rodent models of age-related impairment and alzheimer's disease to humans with amnestic mild cognitive impairment. |
2017-11-16 |
2023-08-13 |
rat |
| Adam D Bachstetter, Eseosa T Ighodaro, Yasmin Hassoun, Danah Aldeiri, Janna H Neltner, Ela Patel, Erin L Abner, Peter T Nelso. Rod-shaped microglia morphology is associated with aging in 2 human autopsy series. Neurobiology of aging. vol 52. 2017-11-16. PMID:28131016. |
alzheimer's disease-related pathology was found to influence the presence of rod-shaped microglia, but only in the parietal cortex and not in the hippocampus or temporal cortex. |
2017-11-16 |
2023-08-13 |
human |
| Tiina Annus, Liam R Wilson, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Young T Hong, Tim D Fryer, Jonathan P Coles, David K Menon, Shahid H Zaman, Anthony J Holland, Peter J Nesto. The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis. Neurobiology of aging. vol 53. 2017-11-16. PMID:28192686. |
in the presence of amyloid neuropathology, the ds brains demonstrated a strikingly similar pattern of posterior dominant cortical thinning and subcortical atrophy in the hippocampus, thalamus, and striatum, to that observed in non-ds alzheimer's disease. |
2017-11-16 |
2023-08-13 |
Not clear |
| Sylvia E Perez, Muhammad Nadeem, Bin He, Jennifer C Miguel, Michael H Malek-Ahmadi, Kewei Chen, Elliott J Mufso. Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease. Neurobiology of aging. vol 54. 2017-11-16. PMID:28365005. |
neocortical and hippocampal trem2 protein levels during the progression of alzheimer's disease. |
2017-11-16 |
2023-08-13 |
human |
| Elisa Scheller, Jessica Peter, Lena V Schumacher, Jacob Lahr, Irina Mader, Christoph P Kaller, Stefan Klöppe. APOE moderates compensatory recruitment of neuronal resources during working memory processing in healthy older adults. Neurobiology of aging. vol 56. 2017-11-16. PMID:28528773. |
using multiple regression models, we identified interactions of apoe variant and age in bilateral hippocampus independently from task performance: ε4 carriers only showed a decrease in activation with increasing age, suggesting high sensitivity of fmri data for detecting changes in alzheimer's disease-relevant brain areas before cognitive decline. |
2017-11-16 |
2023-08-13 |
Not clear |
| Alexander J McDonald, David D Mot. Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory. Journal of neuroscience research. vol 95. issue 3. 2017-11-13. PMID:26876924. |
finally, memory disorders associated with dysfunction or damage to the amygdala, hippocampal region, and/or their interconnections are discussed in relation to alzheimer's disease, posttraumatic stress disorder (ptsd), and temporal lobe epilepsy. |
2017-11-13 |
2023-08-13 |
Not clear |
| Carlos Platero, M Carmen Toba. A fast approach for hippocampal segmentation from T1-MRI for predicting progression in Alzheimer's disease from elderly controls. Journal of neuroscience methods. vol 270. 2017-11-13. PMID:27328371. |
a fast approach for hippocampal segmentation from t1-mri for predicting progression in alzheimer's disease from elderly controls. |
2017-11-13 |
2023-08-13 |
Not clear |