Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Antti J Luikku, Ossi Nerg, Anne M Koivisto, Tuomo Hänninen, Antti Junkkari, Susanna Kemppainen, Sini-Pauliina Juopperi, Rosa Sinisalo, Alli Pesola, Hilkka Soininen, Mikko Hiltunen, Ville Leinonen, Tuomas Rauramaa, Henna Martiskaine. Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome. Journal of neuropathology and experimental neurology. 2024-08-05. PMID:39101555. |
neuropathologic changes of alzheimer disease (ad) including aβ accumulation and neuroinflammation are frequently observed in the cerebral cortex of patients with idiopathic normal pressure hydrocephalus (inph). |
2024-08-05 |
2024-08-07 |
Not clear |
Miriam Aceves, Jose Granados, Ana C Leandro, Juan Peralta, David C Glahn, Sarah Williams-Blangero, Joanne E Curran, John Blangero, Satish Kuma. Role of Neurocellular Endoplasmic Reticulum Stress Response in Alzheimer's Disease and Related Dementias Risk. Genes. vol 15. issue 5. 2024-05-25. PMID:38790197. |
the spread of alzheimer's disease (ad) pathology and progressive neurodegeneration in the hippocampus and cerebral cortex is strongly correlated with cognitive decline in ad patients; however, the molecular underpinning of adrd's causality is still unclear. |
2024-05-25 |
2024-05-27 |
Not clear |
Ling Xiao Yi, Li Zeng, Qing Wang, Eng King Tan, Zhi Dong Zho. Reelin links Apolipoprotein E4, Tau, and Amyloid-β in Alzheimer's disease. Ageing research reviews. vol 98. 2024-05-17. PMID:38754634. |
alzheimer's disease (ad) is the most common neurodegenerative disorder that affects the cerebral cortex and hippocampus, and is characterised by progressive cognitive decline and memory loss. |
2024-05-17 |
2024-05-27 |
mouse |
Michael K Lee, Gang Che. Loss of Cholinergic and Monoaminergic Afferents in International journal of molecular sciences. vol 25. issue 9. 2024-05-11. PMID:38732223. |
loss of cholinergic and monoaminergic afferents in alzheimer's disease (ad) is characterized by a loss of neurons in the cortex and subcortical regions. |
2024-05-11 |
2024-05-27 |
human |
Xuejing Sun, Cui Zhou, Mengwei Ju, Wenjing Feng, Zhiting Guo, Chengyan Qi, Kexin Yang, Rong Xia. Nutrients. vol 16. issue 9. 2024-05-11. PMID:38732535. |
the abnormality in n6-methyladenosine (m6a) methylation is involved in the course of alzheimer's disease (ad), while the intervention of 27-hydroxycholesterol (27-ohc) can affect the m6a methylation modification in the brain cortex. |
2024-05-11 |
2024-05-27 |
Not clear |
Mattia Cort. Exploring tau protein and amyloid-beta propagation: a sensitivity analysis of mathematical models based on biological data. ArXiv. 2024-05-07. PMID:38711430. |
we calibrate the model parameters using biological measurements in the brain cortex for the tau protein and the amyloid-$eta$ in alzheimer's patients and controls. |
2024-05-07 |
2024-05-27 |
Not clear |
Pooja Prabhu, Hirofumi Morise, Kiwamu Kudo, Alexander Beagle, Danielle Mizuiri, Faatimah Syed, Karunakar A Kotegar, Anne Findlay, Bruce L Miller, Joel H Kramer, Katherine P Rankin, Paul A Garcia, Heidi E Kirsch, Keith Vossel, Srikantan S Nagarajan, Kamalini G Ranasingh. Abnormal gamma phase-amplitude coupling in the parahippocampal cortex is associated with network hyperexcitability in Alzheimer's disease. Brain communications. vol 6. issue 2. 2024-04-26. PMID:38665964. |
abnormal gamma phase-amplitude coupling in the parahippocampal cortex is associated with network hyperexcitability in alzheimer's disease. |
2024-04-26 |
2024-04-28 |
human |
Manci Li, Nicole Flack, Peter A Larse. Multifaceted impact of specialized neuropeptide-intensive neurons on the selective vulnerability in Alzheimer's disease. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38014130. |
widespread disruption of neuropeptide (np) networks in alzheimer's disease (ad) and disproportionate absence of neurons expressing high np-producing, coined as hnp neurons, have been reported for the entorhinal cortex (ec) of ad brains. |
2024-04-25 |
2024-04-27 |
Not clear |
Yash Patel, Anita Woo, Sammy Shi, Ramy Ayoub, Jean Shin, Amy Botta, Troy Ketela, Hoon-Ki Sung, Jason Lerch, Brian Nieman, Tomas Paus, Zdenka Pausov. Obesity and the cerebral cortex: Underlying neurobiology in mice and humans. Brain, behavior, and immunity. 2024-04-25. PMID:38663773. |
obesity is a major modifiable risk factor for alzheimer's disease (ad), characterized by progressive atrophy of the cerebral cortex. |
2024-04-25 |
2024-04-28 |
mouse |
Radha Raghuraman, Andrew Aoun, Mathieu Herman, Oliver Shetler, Eden Nahmani, S Abid Hussain. Lateral Entorhinal Cortex Dysfunction in Alzheimer's disease Mice. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659892. |
lateral entorhinal cortex dysfunction in alzheimer's disease mice. |
2024-04-25 |
2024-04-28 |
mouse |
Aya Hassouneh, Bradley Bazuin, Alessander Danna-Dos-Santos, Ilgin Acar, Ikhlas Abdel-Qade. Feature Importance Analysis and Machine Learning for Alzheimer's Disease Early Detection: Feature Fusion of the Hippocampus, Entorhinal Cortex, and Standardized Uptake Value Ratio. Digital biomarkers. vol 8. issue 1. 2024-04-23. PMID:38650695. |
feature importance analysis and machine learning for alzheimer's disease early detection: feature fusion of the hippocampus, entorhinal cortex, and standardized uptake value ratio. |
2024-04-23 |
2024-04-26 |
Not clear |
Mikhail Melnik, Emily Miyoshi, Ricky Ma, Maria Corrada, Claudia Kawas, Ryan Bohannan, Chad Caraway, Carol A Miller, Jason D Hinman, Varghese John, Tina Bilousova, Karen H Gyly. Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer's disease cortex. Journal of neuroscience methods. 2024-04-16. PMID:38626853. |
simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved alzheimer's disease cortex. |
2024-04-16 |
2024-04-19 |
Not clear |
Grace C Smith, Keith R Griffith, Avery R Sicher, Dakota F Brockway, Elizabeth A Proctor, Nicole A Crowle. MODERATE ALCOHOL CONSUMPTION INDUCES LASTING IMPACTS ON PREFRONTAL CORTICAL SIGNALING IN MICE. bioRxiv : the preprint server for biology. 2024-04-15. PMID:38617243. |
both alcohol use disorder (aud) and alzheimer's disease and related dementias (adrd) appear to include disruption in the balance of excitation and inhibition in the cortex, but their potential interactions are unclear. |
2024-04-15 |
2024-04-17 |
mouse |
Neda Shafiee, Vladimir Fonov, Mahsa Dadar, R Nathan Spreng, D Louis Collin. Degeneration in Nucleus basalis of Meynert signals earliest stage of Alzheimer's disease progression. Neurobiology of aging. vol 139. 2024-04-12. PMID:38608458. |
nucleus basalis of meynert (nbm), a crucial source of cholinergic projection to the entorhinal cortex (ec) and hippocampus (hc), has shown sensitivity to neurofibrillary degeneration in the early stages of alzheimer's disease. |
2024-04-12 |
2024-04-15 |
human |
Hanjun Hu, Luoyu Wang, Sammad Abdul, Xue Tang, Qi Feng, Yuzhu Mu, Xiuhong Ge, Zhengluan Liao, Zhongxiang Din. Frequency-dependent alterations in functional connectivity in patients with Alzheimer's Disease spectrum disorders. Frontiers in aging neuroscience. vol 16. 2024-04-12. PMID:38605859. |
in the spectrum of alzheimer's disease (ad) and related disorders, the resting-state functional magnetic resonance imaging (rs-fmri) signals within the cerebral cortex may exhibit distinct characteristics across various frequency ranges. |
2024-04-12 |
2024-04-14 |
Not clear |
Michael Anekson Widjaya, Shin-Da Lee, Wei-Chung Cheng, Bor-Tsang W. Effects of Exercise Training on Immune-Related Genes and Pathways in the Cortex of Animal Models of Alzheimer's Disease: A Systematic Review. Journal of Alzheimer's disease : JAD. 2024-04-05. PMID:38578886. |
effects of exercise training on immune-related genes and pathways in the cortex of animal models of alzheimer's disease: a systematic review. |
2024-04-05 |
2024-04-10 |
Not clear |
Elena Puris, Liudmila Saveleva, Seppo Auriola, Mikko Gynther, Katja M Kanninen, Gert Fricke. Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease. Frontiers in pharmacology. vol 15. 2024-04-04. PMID:38572427. |
sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xfad mouse model of alzheimer's disease. |
2024-04-04 |
2024-04-06 |
mouse |
Mohamadreza Asadie, Ali Miri, Taleb Badri, Javad Hosseini Nejad, Javad Gharechah. Dysregulated AEBP1 and COLEC12 Genes in Late-Onset Alzheimer's Disease: Insights from Brain Cortex and Peripheral Blood Analysis. Journal of molecular neuroscience : MN. vol 74. issue 2. 2024-04-03. PMID:38568322. |
dysregulated aebp1 and colec12 genes in late-onset alzheimer's disease: insights from brain cortex and peripheral blood analysis. |
2024-04-03 |
2024-04-05 |
Not clear |
Masumi Sugiyama, Kenneth S Kosik, Eleni Panagioto. Mathematical topology and geometry-based classification of tauopathies. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555402. |
neurodegenerative diseases, like alzheimer's, are associated with the presence of neurofibrillary lesions formed by tau protein filaments in the cerebral cortex. |
2024-03-30 |
2024-04-02 |
Not clear |
Geidy E Serrano, Jessica Walker, Courtney Nelson, Michael Glass, Richard Arce, Anthony Intorcia, Madison P Cline, Natalie Nabaty, Amanda Acuña, Ashton Huppert Steed, Lucia I Sue, Christine Belden, Parichita Choudhury, Eric Reiman, Alireza Atri, Thomas G Beac. Correlation of Presynaptic and Postsynaptic Proteins with Pathology in Alzheimer's Disease. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542104. |
protein was extracted from the cingulate gyrus, hippocampus, frontal, primary visual, and entorhinal cortex from cognitively unimpaired controls, subjects with mild cognitive impairment (mci), and subjects with dementia that have different levels of alzheimer's pathology. |
2024-03-28 |
2024-03-30 |
human |