| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naoko Kaneko, Hideyuki Okano, Kazunobu Sawamot. Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes to cells : devoted to molecular & cellular mechanisms. vol 11. issue 10. 2006-11-08. PMID:16999735. |
to examine the function of acetylcholine in neurogenesis, we used donepezil (aricept), a potent and selective acetylcholinesterase inhibitor that improves cognitive impairment in alzheimer's disease. |
2006-11-08 |
2023-08-12 |
mouse |
| R Gotti, J Fiori, M Bartolini, V Cavrin. Analysis of Amaryllidaceae alkaloids from Narcissus by GC-MS and capillary electrophoresis. Journal of pharmaceutical and biomedical analysis. vol 42. issue 1. 2006-11-03. PMID:16460902. |
amaryllidaceae are known as ornamental plants, furthermore some species of this family contain galanthamine, an acetylcholinesterase inhibitor approved for the treatment of alzheimer's disease, and other alkaloids with interesting pharmacological activity. |
2006-11-03 |
2023-08-12 |
Not clear |
| Yuki Takator. [Mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of Alzheimer's disease]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 126. issue 8. 2006-11-03. PMID:16880719. |
[mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of alzheimer's disease]. |
2006-11-03 |
2023-08-12 |
rat |
| Yuki Takator. [Mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of Alzheimer's disease]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 126. issue 8. 2006-11-03. PMID:16880719. |
donepezil, galanthamine, and tacrine are therapeutic acetylcholinesterase (ache) inhibitors used for the treatment of alzheimer's disease. |
2006-11-03 |
2023-08-12 |
rat |
| Minoru Fujiki, Takamitsu Hikawa, Tatsuya Abe, Keisuke Ishii, Hidenori Kobayash. Reduced short latency afferent inhibition in diffuse axonal injury patients with memory impairment. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901641. |
a single oral dose (3mg) of donepezil, an acetylcholinesterase inhibitor that is commonly used to treat alzheimer's disease (ad), improved sai in dai patients with wide individual variations that ranged from an increase of 77-18% of test size. |
2006-10-24 |
2023-08-12 |
human |
| Hongjun Fu, Wenming Li, Yuanzhi Lao, Jialie Luo, Nelson T K Lee, Kelvin K W Kan, Hing Wai Tsang, Karl W K Tsim, Yuanping Pang, Zhiwang Li, Donald C Chang, Mingtao Li, Yifan Ha. Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels. Journal of neurochemistry. vol 98. issue 5. 2006-10-03. PMID:16771827. |
beta amyloid protein (abeta) and acetylcholinesterase (ache) have been shown to be closely implicated in the pathogenesis of alzheimer's disease. |
2006-10-03 |
2023-08-12 |
Not clear |
| Cecilia Bartolucci, Mariacristina Siotto, Eleonora Ghidini, Gabriele Amari, Pier Tonino Bolzoni, Marco Racchi, Gino Villetti, Maurizio Delcanale, Doriano Lamb. Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819). Journal of medicinal chemistry. vol 49. issue 17. 2006-10-03. PMID:16913695. |
ganstigmine is an orally active, geneserine derived, carbamate-based acetylcholinesterase inhibitor developed for the treatment of alzheimer's disease. |
2006-10-03 |
2023-08-12 |
Not clear |
| Roberto Raschetti, Marina Maggini, Giacoma Carla Sorrentino, Nello Martini, Bruno Caffari, Nicola Vanacor. A cohort study of effectiveness of acetylcholinesterase inhibitors in Alzheimer's disease. European journal of clinical pharmacology. vol 61. issue 5-6. 2006-09-29. PMID:15912389. |
a cohort study of effectiveness of acetylcholinesterase inhibitors in alzheimer's disease. |
2006-09-29 |
2023-08-12 |
Not clear |
| Roberto Raschetti, Marina Maggini, Giacoma Carla Sorrentino, Nello Martini, Bruno Caffari, Nicola Vanacor. A cohort study of effectiveness of acetylcholinesterase inhibitors in Alzheimer's disease. European journal of clinical pharmacology. vol 61. issue 5-6. 2006-09-29. PMID:15912389. |
to characterise the population of alzheimer's disease patients treated with acetylcholinesterase inhibitors, to analyse effectiveness and drug safety in the clinical practice, and to identify variables that may predict the response to therapy. |
2006-09-29 |
2023-08-12 |
Not clear |
| Kornkanok Ingkaninan, Preeda Phengpa, Supreeya Yuenyongsawad, Nantaka Khoran. Acetylcholinesterase inhibitors from Stephania venosa tuber. The Journal of pharmacy and pharmacology. vol 58. issue 5. 2006-09-29. PMID:16640839. |
acetylcholinesterase (ache) inhibitors have lately gained interest as potential drugs in the treatment of alzheimer's disease. |
2006-09-29 |
2023-08-12 |
Not clear |
| Agneta Nordber. Mechanisms behind the neuroprotective actions of cholinesterase inhibitors in Alzheimer disease. Alzheimer disease and associated disorders. vol 20. issue 2 Suppl 1. 2006-09-28. PMID:16772751. |
inhibitors of the enzyme acetylcholinesterase (ache) are presently used as long-term symptomatic treatments for patients with alzheimer disease (ad), as they enhance central levels of synaptic acetylcholine. |
2006-09-28 |
2023-08-12 |
Not clear |
| Roger M Lane, Steven G Potkin, Albert En. Targeting acetylcholinesterase and butyrylcholinesterase in dementia. The international journal of neuropsychopharmacology. vol 9. issue 1. 2006-09-19. PMID:16083515. |
inhibition of brain acetylcholinesterase (ache) has been the major therapeutic target of che-i treatment strategies for alzheimer's disease (ad). |
2006-09-19 |
2023-08-12 |
Not clear |
| C T Sadashiva, J N Narendra Sharath Chandra, K C Ponnappa, T Veerabasappa Gowda, Kanchugarakoppal S Rangapp. Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer's disease. Bioorganic & medicinal chemistry letters. vol 16. issue 15. 2006-09-11. PMID:16735118. |
synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in alzheimer's disease. |
2006-09-11 |
2023-08-12 |
Not clear |
| Ben Seltze. Donepezil: a review. Expert opinion on drug metabolism & toxicology. vol 1. issue 3. 2006-08-29. PMID:16863459. |
donepezil is a selective acetylcholinesterase inhibitor that is widely prescribed for alzheimer's disease (ad). |
2006-08-29 |
2023-08-12 |
Not clear |
| Christopher Christodoulou, Patricia Melville, William F Scherl, William S Macallister, Leigh E Elkins, Lauren B Krup. Effects of donepezil on memory and cognition in multiple sclerosis. Journal of the neurological sciences. vol 245. issue 1-2. 2006-08-25. PMID:16626752. |
acetylcholinesterase inhibitors are used to treat dementia associated with alzheimer's disease, but their cognitive benefits may extend to additional disorders such as multiple sclerosis (ms). |
2006-08-25 |
2023-08-12 |
human |
| Maria Pia Amato, Emilio Portaccio, Valentina Zipol. Are there protective treatments for cognitive decline in MS? Journal of the neurological sciences. vol 245. issue 1-2. 2006-08-25. PMID:16643949. |
acetylcholinesterase inhibitors (achei) used to treat alzheimer's disease (ad)-such as donepezil, rivastigmine, and galantamine-have recently been tested in other cognitive disorders, including ms. |
2006-08-25 |
2023-08-12 |
Not clear |
| J Porcel, X Montalba. Anticholinesterasics in the treatment of cognitive impairment in multiple sclerosis. Journal of the neurological sciences. vol 245. issue 1-2. 2006-08-25. PMID:16674980. |
treatment with acetylcholinesterase inhibitors (achei) has shown a positive effect on cognitive functions of patients with alzheimer's disease and other conditions such as lewy body dementia, subcortical vascular dementia and parkinson's disease. |
2006-08-25 |
2023-08-12 |
Not clear |
| Claudio Babiloni, Emanuele Cassetta, Gloria Dal Forno, Claudio Del Percio, Florinda Ferreri, Raffaele Ferri, Bartolo Lanuzza, Carlo Miniussi, Davide V Moretti, Flavio Nobili, Roberto D Pascual-Marqui, Guido Rodriguez, Gian Luca Romani, Serenella Salinari, Orazio Zanetti, Paolo M Rossin. Donepezil effects on sources of cortical rhythms in mild Alzheimer's disease: Responders vs. Non-Responders. NeuroImage. vol 31. issue 4. 2006-08-09. PMID:16600641. |
acetylcholinesterase inhibitors (achei) such as donepezil act in mild alzheimer's disease (ad) by increasing cholinergic tone. |
2006-08-09 |
2023-08-12 |
Not clear |
| Denise Harold, Stuart Macgregor, Cathryn E Patterson, Paul Hollingworth, Pamela Moore, Michael J Owen, Julie Williams, Michael O'Donovan, Peter Passmore, Stephen McIlroy, Lesley Jone. A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease. Pharmacogenetics and genomics. vol 16. issue 2. 2006-07-31. PMID:16424819. |
a single nucleotide polymorphism in chat influences response to acetylcholinesterase inhibitors in alzheimer's disease. |
2006-07-31 |
2023-08-12 |
Not clear |
| Sophia Diamant, Erez Podoly, Assaf Friedler, Hagai Ligumsky, Oded Livnah, Hermona Sore. Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 23. 2006-07-19. PMID:16731619. |
in alzheimer's disease, both acetylcholinesterase (ache) and butyrylcholinesterase (bche) colocalize with brain fibrils of amyloid-beta (abeta) peptides, and synaptic ache-s facilitates fibril formation by association with insoluble abeta fibrils. |
2006-07-19 |
2023-08-12 |
human |