All Relations between Alzheimer Disease and acetylcholinesterase

Publication Sentence Publish Date Extraction Date Species
Efe Doğukan Dincel, Faika Başoğlu-Ünal, Ebru Didem Kuran, Tülay Kayra, Nurcan Aydın, Esmanur Kanber, İlhami Gülçin, Nuray Ulusoy-Güzeldemirc. Design, synthesis, and evaluation of novel bistrifluoromethyl-based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease. Chemical biology & drug design. vol 103. issue 2. 2024-02-20. PMID:38378259. design, synthesis, and evaluation of novel bistrifluoromethyl-based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for alzheimer's disease. 2024-02-20 2024-02-23 human
Varish Ahmad, Ibrahim Alotibi, Anwar A Alghamdi, Aftab Ahmad, Qazi Mohammad Sajid Jamal, Supriya Srivastav. Computational Approaches to Evaluate the Acetylcholinesterase Binding Interaction with Taxifolin for the Management of Alzheimer's Disease. Molecules (Basel, Switzerland). vol 29. issue 3. 2024-02-10. PMID:38338420. computational approaches to evaluate the acetylcholinesterase binding interaction with taxifolin for the management of alzheimer's disease. 2024-02-10 2024-02-12 Not clear
Yi-Long Lu, Jing Su, Jian-Wei Li, Wen-Rong X. A molecular container providing supramolecular protection against acetylcholine hydrolysis. Organic & biomolecular chemistry. 2024-02-07. PMID:38323382. alzheimer's disease (ad) is characterized by cognitive decline, often attributed to the deficiency of acetylcholine, which can undergo hydrolysis by acetylcholinesterase (ache) within the biological milieu. 2024-02-07 2024-02-09 Not clear
Bikram Saha, Agnidipta Das, Kailash Jangid, Amit Kumar, Vinod Kumar, Vikas Jaita. Identification of coumarin derivatives targeting acetylcholinesterase for Alzheimer's disease by field-based 3D-QSAR, pharmacophore model-based virtual screening, molecular docking, MM/GBSA, ADME and MD Simulation study. Current research in structural biology. vol 7. 2024-01-31. PMID:38292820. identification of coumarin derivatives targeting acetylcholinesterase for alzheimer's disease by field-based 3d-qsar, pharmacophore model-based virtual screening, molecular docking, mm/gbsa, adme and md simulation study. 2024-01-31 2024-02-02 Not clear
Dhairiya Agarwal, Sumit Kumar, Ramesh Ambatwar, Neeru Bhanwala, Lokesh Chandrakar, Gopal Khati. Lead Identification Through In Silico Studies: Targeting Acetylcholinesterase Enzyme Against Alzheimer's Disease. Central nervous system agents in medicinal chemistry. 2024-01-30. PMID:38288823. lead identification through in silico studies: targeting acetylcholinesterase enzyme against alzheimer's disease. 2024-01-30 2024-02-01 Not clear
Dhairiya Agarwal, Sumit Kumar, Ramesh Ambatwar, Neeru Bhanwala, Lokesh Chandrakar, Gopal Khati. Lead Identification Through In Silico Studies: Targeting Acetylcholinesterase Enzyme Against Alzheimer's Disease. Central nervous system agents in medicinal chemistry. 2024-01-30. PMID:38288823. in this work, we aimed to acquire the best potential small molecule for alzheimer's disease (ad) treatment using different models in biovia discovery studio to identify new potential inhibitors of acetylcholinesterase (ache) via in silico studies. 2024-01-30 2024-02-01 Not clear
Ashish Kumar, Fred Kim, Dong-Keun Song, Jai Jun Choun. Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders. Aging and disease. 2024-01-25. PMID:38270120. for alzheimer's disease (ad), one of the most studied ncd, approved drugs include acetylcholinesterase inhibitors (rivastigmine, donepezil, and galantamine), an nmda receptor antagonist (memantine), and anti-amyloid monoclonal antibodies (aducanumab and lecanemab). 2024-01-25 2024-01-27 Not clear
Swati Singh, Divya Bhatt, Munmun Kumar Singh, Surbhi Bisht, Velusamy Sundaresan, Rajendra Chandra Padalia, Dnyaneshwar U Bawankule, Ram Swaroop Verm. Neuroinflammation and Acetylcholinesterase Inhibitory Potentials of a Spiroketal-Enol Ether Polyyne Isolated from Artemisia pallens Wall. ex DC. Chemistry & biodiversity. 2024-01-24. PMID:38263615. the results showed that d6 has a potential role in the resolution of neuroinflammation, and its acetylcholinesterase inhibitory potential directs further investigation of its role in the management of alzheimer's disease-related pathogenesis. 2024-01-24 2024-01-26 Not clear
Ashwaq H Bataw. The International journal of neuroscience. vol 134. issue 1. 2024-01-16. PMID:35634646. alzheimer's disease (ad) appears as a result of an increase in the accumulation of amyloid beta peptide (aβ) and a decrease in neurotransmitters (acetylcholine) within the brain cells which may be due to increase in acetylcholinesterase (ache) activity and change in expression of apolipoprotein e4 (apoe4) and clusterin (clu) genes. 2024-01-16 2024-01-19 Not clear
Kunal Bhattacharya, Atanu Bhattacharjee, Manodeep Chakrabort. Assessing the potential of Journal of biomolecular structure & dynamics. 2024-01-11. PMID:38205777. assessing the potential of acetylcholinesterase (ache) inhibitors play a crucial role in the treatment of alzheimer's disease. 2024-01-11 2024-01-13 Not clear
S Scott Sutton, Joseph Magagnoli, Tammy H Cummings, James W Hardin, Jayakrishna Ambat. Alzheimer Disease Treatment With Acetylcholinesterase Inhibitors and Incident Age-Related Macular Degeneration. JAMA ophthalmology. 2024-01-04. PMID:38175625. alzheimer disease treatment with acetylcholinesterase inhibitors and incident age-related macular degeneration. 2024-01-04 2024-01-06 Not clear
S Scott Sutton, Joseph Magagnoli, Tammy H Cummings, James W Hardin, Jayakrishna Ambat. Alzheimer Disease Treatment With Acetylcholinesterase Inhibitors and Incident Age-Related Macular Degeneration. JAMA ophthalmology. 2024-01-04. PMID:38175625. alzheimer disease (ad) treatment, acetylcholinesterase inhibitors (acheis), have anti-inflammatory effects and it remains unclear if they modify the risk of amd. 2024-01-04 2024-01-06 Not clear
Shoaib Manzoor, Moustafa T Gabr, Mohamed S Nafie, Md Kausar Raza, Ashma Khan, Shahid M Nayeem, Reem K Arafa, Nasimul Hod. Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy. ACS chemical neuroscience. 2023-12-27. PMID:38149821. discovery of quinolinone hybrids as dual inhibitors of acetylcholinesterase and aβ aggregation for alzheimer's disease therapy. 2023-12-27 2023-12-29 Not clear
Shoaib Manzoor, Moustafa T Gabr, Mohamed S Nafie, Md Kausar Raza, Ashma Khan, Shahid M Nayeem, Reem K Arafa, Nasimul Hod. Discovery of Quinolinone Hybrids as Dual Inhibitors of Acetylcholinesterase and Aβ Aggregation for Alzheimer's Disease Therapy. ACS chemical neuroscience. 2023-12-27. PMID:38149821. we report herein new quinolinone hybrids as dual inhibitors of acetylcholinesterase (ache) and aβ aggregation that function as multitargeted ligands for alzheimer's disease. 2023-12-27 2023-12-29 Not clear
James Calva, Maricarmen Silva, Vladimir Moroch. Composition and Anti-Acetylcholinesterase Properties of the Essential Oil of the Ecuadorian Endemic Species Molecules (Basel, Switzerland). vol 28. issue 24. 2023-12-23. PMID:38138598. composition and anti-acetylcholinesterase properties of the essential oil of the ecuadorian endemic species alzheimer's disease is a global health problem due to the scarcity of acetylcholinesterase inhibitors, the basis for symptomatic treatment of this disease; this requires new approaches to drug discovery. 2023-12-23 2023-12-25 Not clear
Bing Zhang, Yu Wang, Donghui Wu, Qilin Zhao, Yaoyao Chen, Yushu Li, Jian Sun, Xiurong Yan. Fluorescent assay for acetylcholinesterase activity and inhibitor screening based on lanthanide organic/inorganic hybrid materials. Analytical methods : advancing methods and applications. 2023-12-20. PMID:38116865. it is of great significance for the clinical diagnosis of alzheimer's disease (ad) to achieve the on-site activity evaluation of acetylcholinesterase (ache), the hydrolase of acetylcholine (ach). 2023-12-20 2023-12-23 Not clear
Farida Begum, Muhammad Yousaf, Sajid Iqbal, Nazif Ullah, Anwar Hussain, Momin Khan, Asaad Khalid, Alanood S Algarni, Ashraf N Abdalla, Ajmal Khan, Muhammad Arif Lodhi, Ahmed Al-Harras. Inhibition of Acetylcholinesterase with Novel 1, 3, 4, Oxadiazole Derivatives: A Kinetic, ACS omega. vol 8. issue 49. 2023-12-19. PMID:38107974. inhibition of acetylcholinesterase with novel 1, 3, 4, oxadiazole derivatives: a kinetic, alzheimer's disease (ad) is a neurological disease that disturbs the memory, thinking skills, and behavior of the affected person. 2023-12-19 2023-12-21 Not clear
Jucheng Xia, Shuanghong Dong, Lili Yang, Fang Wang, Siqi Xing, Jiyu Du, Zeng L. Design, synthesis, and biological evaluation of novel tryptanthrin derivatives as selective acetylcholinesterase inhibitors for the treatment of Alzheimer's disease. Bioorganic chemistry. vol 143. 2023-11-25. PMID:38006789. design, synthesis, and biological evaluation of novel tryptanthrin derivatives as selective acetylcholinesterase inhibitors for the treatment of alzheimer's disease. 2023-11-25 2023-11-28 Not clear
Letícia Basso, Silvia Cristina Fagundes, Tatiana Staudt, Karini da Rosa, Elizane Langaro, Hamid Omidian, Charise Dallazem Berto. Transdermal Therapeutic Systems for the Treatment of Alzheimer's Disease: A Patent Review. CNS & neurological disorders drug targets. 2023-11-22. PMID:37990896. two classes of medications are used to treat alzheimer's disease (ad); donepezil, galantamine, and rivastigmine are acetylcholinesterase inhibitors, and memantine is a non-competitive antagonist of the n-methyl-d-aspartate receptor. 2023-11-22 2023-11-29 Not clear
Hongtao Du, Jinzhi Song, Fang Ma, Hongxin Gao, Xinyan Zhao, Renjun Mao, Xiaolong He, Yan Ya. Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer's disease. Journal of enzyme inhibition and medicinal chemistry. vol 38. issue 1. 2023-11-15. PMID:37965884. novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of alzheimer's disease. 2023-11-15 2023-11-20 Not clear