| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Y Ho, A J Weissberger, P Marbach, L Lazaru. Therapeutic efficacy of the somatostatin analog SMS 201-995 (octreotide) in acromegaly. Effects of dose and frequency and long-term safety. Annals of internal medicine. vol 112. issue 3. 1990-02-16. PMID:2404445. |
therapeutic efficacy of the somatostatin analog sms 201-995 (octreotide) in acromegaly. |
1990-02-16 |
2023-08-11 |
Not clear |
| K Y Ho, A J Weissberger, P Marbach, L Lazaru. Therapeutic efficacy of the somatostatin analog SMS 201-995 (octreotide) in acromegaly. Effects of dose and frequency and long-term safety. Annals of internal medicine. vol 112. issue 3. 1990-02-16. PMID:2404445. |
to determine the efficacy of stepwise incremental doses, to compare twice- with thrice-daily administration of the same total daily dosage of the long-acting somatostatin analog sms 201-995 (octreotide, sandoz australia, sydney, australia), and to evaluate the risk for cholelithiasis after long-term therapy for acromegaly. |
1990-02-16 |
2023-08-11 |
Not clear |
| P A van Liessum, G F Pieters, A G Smals, L M Swinkels, T J Benraad, P W Kloppenbor. Does SMS 201-995 normalize growth hormone secretion in acromegaly? GH day profiles and GH concentrations after oral glucose loading. Journal of endocrinological investigation. vol 12. issue 8. 1990-01-25. PMID:2592740. |
gh secretion in acromegaly was studied in 8 patients before and during treatment with sms 201-995, a somatostatin analogue, 100 micrograms twice daily, by evaluating gh day profiles and gh suppressibility after oral glucose tolerance tests (ogtt). |
1990-01-25 |
2023-08-11 |
Not clear |
| P A van Liessum, G F Pieters, A G Smals, A R Hermus, T J Benraad, P W Kloppenbor. Single-dose response study of the somatostatin analogue octreotide in acromegaly. Acta endocrinologica. vol 121. issue 5. 1989-12-28. PMID:2686331. |
single-dose response study of the somatostatin analogue octreotide in acromegaly. |
1989-12-28 |
2023-08-11 |
Not clear |
| P A van Liessum, G F Pieters, A G Smals, A R Hermus, T J Benraad, P W Kloppenbor. Single-dose response study of the somatostatin analogue octreotide in acromegaly. Acta endocrinologica. vol 121. issue 5. 1989-12-28. PMID:2686331. |
the recommended dosage schedules for intermittent sc therapy with the somatostatin analogue octreotide in acromegaly vary widely, from 100 to 1500 micrograms daily. |
1989-12-28 |
2023-08-11 |
Not clear |
| A Shimatsu, H Imura, M Irie, S Nakagawa, Y Goto, N Shimizu, R Takeda, Y Kato, S Saito, H Ibayash. [A multicenter clinical trial of SMS 201-995 (octreotide acetate) in acromegaly and gigantism]. Nihon Naibunpi Gakkai zasshi. vol 65. issue 7. 1989-12-26. PMID:2684694. |
sixty-four patients with active acromegaly and three patients with gigantism were treated with the long acting somatostatin analog sms 201-995 (50-500 micrograms, sc, every 6-12 h or 150-880 micrograms daily by intermittent sc infusion, for up to 114 weeks). |
1989-12-26 |
2023-08-11 |
Not clear |
| O Serri, M Somma, E Rasio, P Brazea. Growth hormone-releasing factor increases serum prolactin concentrations in normal subjects and in patients with pituitary adenomas. Clinical endocrinology. vol 30. issue 1. 1989-10-24. PMID:2505955. |
moreover, the data suggest that in acromegaly there is a relative functional deficiency of hypothalamic somatostatin. |
1989-10-24 |
2023-08-11 |
human |
| S Natori, S Ikuyama, M Haji, M Ohashi, H Nawat. Growth hormone releasing hormone-sensitive adenylate cyclase activity in growth hormone-producing pituitary adenoma: correlation to the response of plasma growth hormone to growth hormone releasing hormone in patients with acromegaly. Endocrinologia japonica. vol 36. issue 2. 1989-10-16. PMID:2550207. |
these results suggest that ghrh-induced gh release from gh-producing pituitary adenomas of patients with acromegaly may be regulated not only by ghrh receptor-adenylate cyclase system but also modified by several other factors including somatostatin and sm-c. |
1989-10-16 |
2023-08-11 |
Not clear |
| C Wang, K S Lam, E Arceo, F L Cha. Comparison of the effectiveness of 2-hourly versus 8-hourly subcutaneous injections of a somatostatin analog (SMS 201-995) in the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 3. 1989-09-15. PMID:2668325. |
comparison of the effectiveness of 2-hourly versus 8-hourly subcutaneous injections of a somatostatin analog (sms 201-995) in the treatment of acromegaly. |
1989-09-15 |
2023-08-11 |
human |
| C Wang, K S Lam, E Arceo, F L Cha. Comparison of the effectiveness of 2-hourly versus 8-hourly subcutaneous injections of a somatostatin analog (SMS 201-995) in the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 3. 1989-09-15. PMID:2668325. |
to determine whether sc injections of a somatostatin analog (sms 201-995) every 2 h (q2h) is more effective than sc injections every 8 h (q8h) in achieving a constant suppression of gh levels and a more satisfactory clinical response, we studied 10 patients with acromegaly (4 newly diagnosed and 6 previously treated with bromocriptine/pituitary irradiation/transfrontal hypophysectomy). |
1989-09-15 |
2023-08-11 |
human |
| P A van Liessum, W P Hopman, G F Pieters, J B Jansen, A G Smals, G Rosenbusch, P W Kloppenborg, C B Lamer. Postprandial gallbladder motility during long term treatment with the long-acting somatostatin analog SMS 201-995 in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 3. 1989-09-15. PMID:2760170. |
postprandial gallbladder motility during long term treatment with the long-acting somatostatin analog sms 201-995 in acromegaly. |
1989-09-15 |
2023-08-11 |
Not clear |
| P A van Liessum, W P Hopman, G F Pieters, J B Jansen, A G Smals, G Rosenbusch, P W Kloppenborg, C B Lamer. Postprandial gallbladder motility during long term treatment with the long-acting somatostatin analog SMS 201-995 in acromegaly. The Journal of clinical endocrinology and metabolism. vol 69. issue 3. 1989-09-15. PMID:2760170. |
the effects on gallbladder motility of long term treatment with the somatostatin analog sms 201-995 (sms) were studied in five patients with acromegaly treated for 6-32 months with 200-300 micrograms sms daily. |
1989-09-15 |
2023-08-11 |
Not clear |
| b' V R Paunovi\\xc4\\x87, V Popovi\\xc4\\x8. The development of dependence to an octapeptide somatostatin analog: contribution to the study of somatostatin analgesia. Biological psychiatry. vol 26. issue 1. 1989-07-06. PMID:2541810.' |
this paper reports the phenomenon of dependence to a somatostatin octapeptide analog used for the treatment of acromegaly and severe headache. |
1989-07-06 |
2023-08-11 |
Not clear |
| H J Quabbe, U Plöckinge. Dose-response study and long term effect of the somatostatin analog octreotide in patients with therapy-resistant acromegaly. The Journal of clinical endocrinology and metabolism. vol 68. issue 5. 1989-06-09. PMID:2565912. |
dose-response study and long term effect of the somatostatin analog octreotide in patients with therapy-resistant acromegaly. |
1989-06-09 |
2023-08-11 |
Not clear |
| J P Tauber, T Babin, M T Tauber, F Vigoni, A Bonafe, M Ducasse, A G Harris, F Bayar. Long term effects of continuous subcutaneous infusion of the somatostatin analog octreotide in the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 68. issue 5. 1989-06-09. PMID:2565913. |
long term effects of continuous subcutaneous infusion of the somatostatin analog octreotide in the treatment of acromegaly. |
1989-06-09 |
2023-08-11 |
Not clear |
| C F Kwok, L T H. The suppression of blood growth hormone level by somatostatin infusion in patients with active acromegaly. Zhonghua yi xue za zhi = Chinese medical journal; Free China ed. vol 42. issue 4. 1989-06-06. PMID:2907415. |
the suppression of blood growth hormone level by somatostatin infusion in patients with active acromegaly. |
1989-06-06 |
2023-08-11 |
Not clear |
| R Miranda, A Zárate, G Ruíz Velasc. Effective treatment of recurrent acromegaly with a long-active somatostatin analogue (sandostatin). Archivos de investigacion medica. vol 19. issue 4. 1989-06-06. PMID:3245759. |
effective treatment of recurrent acromegaly with a long-active somatostatin analogue (sandostatin). |
1989-06-06 |
2023-08-11 |
Not clear |
| W E Cobb, I M Jackso. Short-term recovery of visual field loss in acromegaly during treatment with a long-acting somatostatin analogue. The American journal of medicine. vol 86. issue 4. 1989-05-02. PMID:2929643. |
short-term recovery of visual field loss in acromegaly during treatment with a long-acting somatostatin analogue. |
1989-05-02 |
2023-08-11 |
Not clear |
| J C Reubi, A M Landol. The growth hormone responses to octreotide in acromegaly correlate with adenoma somatostatin receptor status. The Journal of clinical endocrinology and metabolism. vol 68. issue 4. 1989-04-14. PMID:2537844. |
the growth hormone responses to octreotide in acromegaly correlate with adenoma somatostatin receptor status. |
1989-04-14 |
2023-08-11 |
Not clear |
| T L Peeters, K W Romanski, J Janssens, G Vantrappe. Effect of the long-acting somatostatin analogue SMS 201-995 on small-intestinal interdigestive motility in the dog. Scandinavian journal of gastroenterology. vol 23. issue 7. 1989-04-06. PMID:3227290. |
the long-acting somatostatin analogue sms 201-995, also called sandostatin, is used in the treatment of acromegaly and peptide-secreting tumors. |
1989-04-06 |
2023-08-11 |
dog |