| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Moisés Mercad. Somatostatin analog withdrawal in patients with acromegaly: an elusive goal? Endocrine. vol 46. issue 3. 2015-04-02. PMID:24736999. |
somatostatin analog withdrawal in patients with acromegaly: an elusive goal? |
2015-04-02 |
2023-08-13 |
Not clear |
| Adnan Ajmal, Arezoo Haghshenas, Shirin Attarian, Maya Barake, Nicholas A Tritos, Anne Klibanski, Karen K Miller, Lisa B Nachtigal. The effect of somatostatin analogs on vitamin D and calcium concentrations in patients with acromegaly. Pituitary. vol 17. issue 4. 2015-02-23. PMID:24002366. |
the effect of somatostatin analogs on vitamin d and calcium concentrations in patients with acromegaly. |
2015-02-23 |
2023-08-12 |
Not clear |
| Adnan Ajmal, Arezoo Haghshenas, Shirin Attarian, Maya Barake, Nicholas A Tritos, Anne Klibanski, Karen K Miller, Lisa B Nachtigal. The effect of somatostatin analogs on vitamin D and calcium concentrations in patients with acromegaly. Pituitary. vol 17. issue 4. 2015-02-23. PMID:24002366. |
the goals of this study were to determine: (1) 25oh vitamin d (25ohd) and calcium levels in patients with acromegaly and their association with insulin-like growth factor (igf-1) and (2) whether somatostatin analog (ssa) therapy effects calcium and 25ohd levels. |
2015-02-23 |
2023-08-12 |
Not clear |
| Marinella Tzanela, Dimitra A Vassiliadi, Nikolaos Gavalas, Andrea Szabo, Eleni Margelou, Athina Valatsou, Charalambos Vassilopoulo. Glucose homeostasis in patients with acromegaly treated with surgery or somatostatin analogues. Clinical endocrinology. vol 75. issue 1. 2015-02-09. PMID:21521267. |
glucose homeostasis in patients with acromegaly treated with surgery or somatostatin analogues. |
2015-02-09 |
2023-08-12 |
Not clear |
| Marinella Tzanela, Dimitra A Vassiliadi, Nikolaos Gavalas, Andrea Szabo, Eleni Margelou, Athina Valatsou, Charalambos Vassilopoulo. Glucose homeostasis in patients with acromegaly treated with surgery or somatostatin analogues. Clinical endocrinology. vol 75. issue 1. 2015-02-09. PMID:21521267. |
long-acting somatostatin analogues (ssa) are widely used for the treatment of acromegaly; however, they also alter β-cell function by inhibiting insulin secretion. |
2015-02-09 |
2023-08-12 |
Not clear |
| S J C M M Neggers, S E Franck, F W M de Rooij, A H G Dallenga, R M L Poublon, R A Feelders, J A M J L Janssen, M Buchfelder, L J Hofland, J O L Jørgensen, A J van der Lel. Long-term efficacy and safety of pegvisomant in combination with long-acting somatostatin analogs in acromegaly. The Journal of clinical endocrinology and metabolism. vol 99. issue 10. 2015-01-22. PMID:24937542. |
long-term efficacy and safety of pegvisomant in combination with long-acting somatostatin analogs in acromegaly. |
2015-01-22 |
2023-08-13 |
Not clear |
| Magdy Shenouda, Mario Maldonado, Yanfeng Wang, Emmanuel Bouillaud, Michelle Hudson, Dalal Nesheiwat, Ke H. An open-label dose-escalation study of once-daily and twice-daily pasireotide in healthy volunteers: safety, tolerability, and effects on glucose, insulin, and glucagon levels. American journal of therapeutics. vol 21. issue 3. 2014-12-24. PMID:22713526. |
pasireotide is a multireceptor-targeted somatostatin analogue that has high affinity for 4 of the 5 somatostatin receptor subtypes (sst1,2,3 and sst5) and has therapeutic potential in conditions with tumors of neuroendocrine origin, such as cushing disease, acromegaly, and neuroendocrine tumors. |
2014-12-24 |
2023-08-12 |
human |
| Astrid Breitschaft, Ke Hu, Karina Hermosillo Reséndiz, Christelle Darstein, Georg Golo. Management of hyperglycemia associated with pasireotide (SOM230): healthy volunteer study. Diabetes research and clinical practice. vol 103. issue 3. 2014-10-30. PMID:24461109. |
pasireotide, a multireceptor-targeted somatostatin analogue with efficacy in cushing's disease and acromegaly, can affect glucose metabolism due to inhibition of insulin secretion and incretin hormone responses. |
2014-10-30 |
2023-08-12 |
human |
| Giuseppe Reimondo, Marta Bondanelli, Maria Rosaria Ambrosio, Franco Grimaldi, Barbara Zaggia, Maria Chiara Zatelli, Barbara Allasino, Federica Laino, Emiliano Aroasio, Angela Termine, Pierantonio Conton, Agostino Paoletta, Ernesto Demenis, Ettore Degli Uberti, Massimo Terzol. Growth hormone values after an oral glucose load do not add clinically useful information in patients with acromegaly on long-term somatostatin receptor ligand treatment. Endocrine. vol 45. issue 1. 2014-10-10. PMID:23794116. |
growth hormone values after an oral glucose load do not add clinically useful information in patients with acromegaly on long-term somatostatin receptor ligand treatment. |
2014-10-10 |
2023-08-12 |
Not clear |
| Yuedi Ding, Jun Fan, Wenxin Li, Ying Peng, Runlin Yang, Lili Deng, Qiang F. The effect of albumin fusion structure on the production and bioactivity of the somatostatin-28 fusion protein in Pichia pastoris. Journal of industrial microbiology & biotechnology. vol 41. issue 6. 2014-09-11. PMID:24752560. |
somatostatin, a natural inhibitor of growth hormone (gh), and its analogs have been used in clinical settings for the treatment of acromegaly, gigantism, thyrotropinoma, and other carcinoid syndromes. |
2014-09-11 |
2023-08-13 |
Not clear |
| S L Fougner, J Bollerslev, J Svartberg, M Øksnes, J Cooper, S M Carlse. Preoperative octreotide treatment of acromegaly: long-term results of a randomised controlled trial. European journal of endocrinology. vol 171. issue 2. 2014-08-11. PMID:24866574. |
randomised studies have demonstrated a beneficial effect of pre-surgical treatment with somatostatin analogues (ssa) in acromegaly when evaluated early postoperatively. |
2014-08-11 |
2023-08-13 |
Not clear |
| Arnaud Capron, Jennifer Destree, Dominique Maiter, Pierre Wallemac. Validation of a rapid liquid chromatography-tandem mass spectrometric assay for the determination of octreotide plasma concentrations. Clinical biochemistry. vol 47. issue 1-2. 2014-08-04. PMID:23872204. |
the aim of this study was to develop and validate a fast liquid chromatography-tandem mass spectrometric (lc-msms) assay to determine circulating concentrations of octreotide (a somatostatin analog used in acromegaly and neuroendocrine tumors) in patients' plasma samples. |
2014-08-04 |
2023-08-12 |
Not clear |
| Jessica Brzana, Chris G Yedinak, Sakir H Gultekin, Johnny B Delashaw, Maria Fleseri. Growth hormone granulation pattern and somatostatin receptor subtype 2A correlate with postoperative somatostatin receptor ligand response in acromegaly: a large single center experience. Pituitary. vol 16. issue 4. 2014-07-29. PMID:23184260. |
growth hormone granulation pattern and somatostatin receptor subtype 2a correlate with postoperative somatostatin receptor ligand response in acromegaly: a large single center experience. |
2014-07-29 |
2023-08-12 |
Not clear |
| John D Carmichael, Vivien S Bonert, Miriam Nuño, Diana Ly, Shlomo Melme. Acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis. The Journal of clinical endocrinology and metabolism. vol 99. issue 5. 2014-07-10. PMID:24606084. |
acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis. |
2014-07-10 |
2023-08-12 |
Not clear |
| John D Carmichael, Vivien S Bonert, Miriam Nuño, Diana Ly, Shlomo Melme. Acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis. The Journal of clinical endocrinology and metabolism. vol 99. issue 5. 2014-07-10. PMID:24606084. |
biochemical efficacy of somatostatin receptor ligand (srl) treatment in acromegaly is defined by metrics for gh and igf-1 control. |
2014-07-10 |
2023-08-12 |
Not clear |
| Andrea Giustina, Ioannis Karamouzis, Ilaria Patelli, Gherardo Mazziott. Octreotide for acromegaly treatment: a reappraisal. Expert opinion on pharmacotherapy. vol 14. issue 17. 2014-06-10. PMID:24124691. |
this article covers the recent available evidences published on octreotide , the first somatostatin analog introduced into clinical practice for the medical treatment of acromegaly. |
2014-06-10 |
2023-08-12 |
Not clear |
| Tetsuhiro Kitamura, Michio Otsuki, Masaya Yamaoka, Youichi Saitoh, Iichiro Shimomur. The temporary drop of serum octreotide concentration deteriorated ventricular tachycardia in an acromegalic patient. Endocrine journal. vol 60. issue 10. 2014-06-02. PMID:23856885. |
octreotide is a somatostatin analog that has been used for medical therapy for acromegaly. |
2014-06-02 |
2023-08-12 |
Not clear |
| Trevor A Howlett, Debbie Willis, Gillian Walker, John A H Wass, Peter J Traine. Control of growth hormone and IGF1 in patients with acromegaly in the UK: responses to medical treatment with somatostatin analogues and dopamine agonists. Clinical endocrinology. vol 79. issue 5. 2014-05-08. PMID:23574573. |
control of growth hormone and igf1 in patients with acromegaly in the uk: responses to medical treatment with somatostatin analogues and dopamine agonists. |
2014-05-08 |
2023-08-12 |
Not clear |
| Sarmistha Banerjee, Rajat Kumar Das, Bernard H Shapir. Growth hormone-independent suppression of growth hormone-dependent female isoforms of cytochrome P450 by the somatostatin analog octreotide. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23707186. |
octreotide is a potent somatostatin analog therapeutically used to treat several conditions including hyper growth hormone secretion in patients with acromegaly. |
2014-04-14 |
2023-08-12 |
human |
| M Mai, A Tönjes, C Trantakis, C Wittekind, M Stumvoll, D Führe. [Hirsutism and multinodular goiter in a 40-year-old female watchmaker]. Der Internist. vol 54. issue 9. 2014-04-07. PMID:23921839. |
in the presence of typical clinical features of acromegaly but a lack of evidence for a pituitary adenoma the results of somatostatin receptor scintigraphy were indicative of a typical carcinoid of the lungs as the cause of the ectopic secretion of ghrh and the stimulation of pituitary gland growth hormone secretion resulting in acromegaly. |
2014-04-07 |
2023-08-12 |
Not clear |