| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wojciech Zgliczyński, Piotr Zdunowsk. [Pegvisomant--growth hormone receptor antagonist in the treatment of acromegaly]. Endokrynologia Polska. vol 58. issue 5. 2008-04-11. PMID:18058736. |
pegvisomant, growth hormone (gh) antagonist is a new perspective in the treatment of acromegaly. |
2008-04-11 |
2023-08-12 |
Not clear |
| Katica Bajuk Studen, Ariel Barka. Assessment of the magnitude of growth hormone hypersecretion in active acromegaly: reliability of different sampling models. The Journal of clinical endocrinology and metabolism. vol 93. issue 2. 2008-04-10. PMID:18029464. |
the pulsatility of gh secretion in acromegaly poses difficulty in ascertaining true daily gh milieu in patients with this disease. |
2008-04-10 |
2023-08-12 |
Not clear |
| Patricia Fainstein Day, Lawrence Frohman, Hernan Garcia Rivello, Jean Claude Reubi, Gustavo Sevlever, Mariela Glerean, Tomas Fernandez Gianotti, Marcelo Pietrani, Alejandra Rabadan, Silvina Racioppi, Martin Bidlingmaie. Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment. Pituitary. vol 10. issue 3. 2008-04-02. PMID:17373589. |
endocrine evaluation confirmed acromegaly plasma igf-1: 984 ng/ml (63-380), gh: 49.8 ng/ml (<5). |
2008-04-02 |
2023-08-12 |
human |
| I M Holdawa. Excess mortality in acromegaly. Hormone research. vol 68 Suppl 5. 2008-03-20. PMID:18174739. |
increased production of growth hormone (gh) and insulin-like growth factor-i (igf-i) in patients with acromegaly is associated with a twofold increase in mortality compared with the general population. |
2008-03-20 |
2023-08-12 |
Not clear |
| Hidenori Fukuoka, Yutaka Takahashi, Keiji Iida, Takumi Kudo, Hitoshi Nishizawa, Mari Imanaka, Ryoko Takeno, Genzo Iguchi, Kentaro Takahashi, Yasuhiko Okimura, Hidesuke Kaji, Kazuo Chihar. Low serum IGF-I/GH ratio is associated with abnormal glucose tolerance in acromegaly. Hormone research. vol 69. issue 3. 2008-03-13. PMID:18219220. |
in addition, diverse actions of gh and igf-i in regulating glucose metabolism in acromegaly have not yet been well elucidated. |
2008-03-13 |
2023-08-12 |
Not clear |
| Brian K Roberts, Daniel L Ouyang, Shivanand P Lad, Steven D Chang, Griffith R Harsh, John R Adler, Scott G Soltys, Iris C Gibbs, Lynn Remedios, Laurence Katznelso. Efficacy and safety of CyberKnife radiosurgery for acromegaly. Pituitary. vol 10. issue 1. 2008-02-04. PMID:17273921. |
acromegaly is a disease characterized by gh hypersecretion, and is typically caused by a pituitary somatotroph adenoma. |
2008-02-04 |
2023-08-12 |
Not clear |
| Jens Fuglsan. Ghrelin in pregnancy and lactation. Vitamins and hormones. vol 77. 2008-02-01. PMID:17983860. |
at the same time the maternal organism increases its fat mass, becomes insulin resistant and the growth hormone (gh) axis is dominated by placental growth hormone circulating in concentrations comparable to gh levels observed in acromegaly. |
2008-02-01 |
2023-08-12 |
human |
| L Tauchmanova, C Di Somma, A Rusciano, G Lombardi, A Cola. The role for growth hormone in linking arthritis, osteoporosis, and body composition. Journal of endocrinological investigation. vol 30. issue 6 Suppl. 2008-01-28. PMID:17721072. |
their normalization (by gh replacement or treatment of acromegaly) reverses most of these abnormalities, thus confirming their gh-related etiology. |
2008-01-28 |
2023-08-12 |
human |
| Dong Jun Lim, Hyuk Sang Kwon, Jae Hyoung Cho, Sang Hee Kim, Yoon Hee Choi, Kun Ho Yoon, Bong Yun Cha, Kwang Woo Lee, Ho Young Son, Sung Koo Kan. Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia. Endocrine journal. vol 54. issue 4. 2008-01-14. PMID:17575366. |
acromegaly is caused by excessive secretion of growth hormone (gh), and a resultant persistent elevation of insulin-like growth factor-1 (igf-1) levels. |
2008-01-14 |
2023-08-12 |
Not clear |
| Dong Jun Lim, Hyuk Sang Kwon, Jae Hyoung Cho, Sang Hee Kim, Yoon Hee Choi, Kun Ho Yoon, Bong Yun Cha, Kwang Woo Lee, Ho Young Son, Sung Koo Kan. Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia. Endocrine journal. vol 54. issue 4. 2008-01-14. PMID:17575366. |
however, in the first screening test, gh levels were high and igf-1 levels were inappropriately normal so the results were not close to the diagnosis of acromegaly. |
2008-01-14 |
2023-08-12 |
Not clear |
| Dong Jun Lim, Hyuk Sang Kwon, Jae Hyoung Cho, Sang Hee Kim, Yoon Hee Choi, Kun Ho Yoon, Bong Yun Cha, Kwang Woo Lee, Ho Young Son, Sung Koo Kan. Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia. Endocrine journal. vol 54. issue 4. 2008-01-14. PMID:17575366. |
after several-months insulin treatment, igf-1 levels were increased to the abnormal state and gh levels were decreased without treatment for acromegaly. |
2008-01-14 |
2023-08-12 |
Not clear |
| Omar Ali, Swati Banerjee, Daniel F Kelly, Phillip D K Le. Management of type 2 diabetes mellitus associated with pituitary gigantism. Pituitary. vol 10. issue 4. 2008-01-10. PMID:17629784. |
in the adult condition of gh excess, acromegaly, the occurrence of type 2 diabetes mellitus (t2dm) and diabetic ketoacidosis (dka) have been reported, with resolution following normalization of gh levels. |
2008-01-10 |
2023-08-12 |
Not clear |
| Darko Kastelan, Tina Dusek, Ivana Kraljevic, Ozren Polasek, Zdravko Perkovic, Iva Kardum, Zlatko Giljevic, Jozo Jelcic, Izet Aganovic, Mirko Korsi. Bone properties in patients with acromegaly: quantitative ultrasound of the heel. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. vol 10. issue 3. 2007-12-18. PMID:17543559. |
growth hormone (gh) deficiency and acromegaly serve as good models for investigating the effects of gh on bone remodeling. |
2007-12-18 |
2023-08-12 |
human |
| Caroline Sievers, Harald Jorn Schneider, Gunter Karl Stall. Insulin-like growth factor-1 in plasma and brain: regulation in health and disease. Frontiers in bioscience : a journal and virtual library. vol 13. 2007-12-11. PMID:17981530. |
acromegaly due to jgh and igf-1 excess and growth hormone deficiency with decreased gh and igf-1 might serve as models to study igf-1 function, but the effects of gh and igf-1 in these conditions are often indistinguishable. |
2007-12-11 |
2023-08-12 |
Not clear |
| Ignacio Alejandro Martínez-Delgado, Graciela Gómez-Martíne. [Usefulness of GH and IGF-1 to establish the dose and frequency of application of octreotide to treat acromegaly]. Revista medica del Instituto Mexicano del Seguro Social. vol 45. issue 3. 2007-12-06. PMID:17692168. |
[usefulness of gh and igf-1 to establish the dose and frequency of application of octreotide to treat acromegaly]. |
2007-12-06 |
2023-08-12 |
Not clear |
| Ignacio Alejandro Martínez-Delgado, Graciela Gómez-Martíne. [Usefulness of GH and IGF-1 to establish the dose and frequency of application of octreotide to treat acromegaly]. Revista medica del Instituto Mexicano del Seguro Social. vol 45. issue 3. 2007-12-06. PMID:17692168. |
to determine the dose and frequency of application of octreotide lar to treat acromegaly by monitoring the levels of circulating growth hormone (gh) and insulin-like growth factor (igf-1). |
2007-12-06 |
2023-08-12 |
Not clear |
| A Pokrajac, G Wark, A R Ellis, J Wear, G E Wieringa, P J Traine. Variation in GH and IGF-I assays limits the applicability of international consensus criteria to local practice. Clinical endocrinology. vol 67. issue 1. 2007-11-20. PMID:17437512. |
recent criteria state that acromegaly is excluded by a nadir gh during an oral glucose tolerance test (ogtt) of < 1 microg/l and a normal level of igf-i. |
2007-11-20 |
2023-08-12 |
Not clear |
| Takakazu Kawamata, Akio Inui, Hiroshi Hosoda, Kenji Kangawa, Tomokatsu Hor. Perioperative plasma active and total ghrelin levels are reduced in acromegaly when compared with in nonfunctioning pituitary tumours even after normalization of serum GH. Clinical endocrinology. vol 67. issue 1. 2007-11-20. PMID:17466003. |
perioperative plasma active and total ghrelin levels are reduced in acromegaly when compared with in nonfunctioning pituitary tumours even after normalization of serum gh. |
2007-11-20 |
2023-08-12 |
Not clear |
| Fausto Bogazzi, Francesco Raggi, Federica Ultimieri, Dania Russo, Antonella Manariti, Aldo D'Alessio, Paolo Viacava, Giovanni Fanelli, Maurizio Gasperi, Luigi Bartalena, Enio Martin. Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH. The Journal of endocrinology. vol 194. issue 3. 2007-11-20. PMID:17761891. |
heart hypertrophy is a common finding of acromegaly, a syndrome due to gh excess. |
2007-11-20 |
2023-08-12 |
mouse |
| Einar Osland Vik-Mo, Marianne Oksnes, Paal-Henning Pedersen, Tore Wentzel-Larsen, Eyvind Rødahl, Frits Thorsen, Thomas Schreiner, Sylvi Aanderud, Morten Lund-Johanse. Gamma knife stereotactic radiosurgery for acromegaly. European journal of endocrinology. vol 157. issue 3. 2007-11-19. PMID:17766706. |
gamma knife radiosurgery (gkr) is an adjuvant treatment for acromegaly if surgery fails to normalize gh hypersecretion. |
2007-11-19 |
2023-08-12 |
Not clear |