Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Philip C Johnston, Amir H Hamrahian, Richard A Prayson, Laurence Kennedy, Robert J Wei. Thyrotoxicosis with absence of clinical features of acromegaly in a TSH- and GH-secreting, invasive pituitary macroadenoma. Endocrinology, diabetes & metabolism case reports. vol 2015. 2015-01-23. PMID:25614823. |
tsh-secreting adenomas can co-secrete other hormones including gh, prolactin, and gonadotropins; conversely, co-secretion of tsh from a pituitary adenoma in acromegaly is infrequent. |
2015-01-23 |
2023-08-13 |
Not clear |
Carlos Reyes-Vidal, Jean Carlos Fernandez, Jeffrey N Bruce, Celina Crisman, Irene M Conwell, Jane Kostadinov, Eliza B Geer, Kalmon D Post, Pamela U Fred. Prospective study of surgical treatment of acromegaly: effects on ghrelin, weight, adiposity, and markers of CV risk. The Journal of clinical endocrinology and metabolism. vol 99. issue 11. 2015-01-16. PMID:25137427. |
although epidemiological studies have found that gh and igf-1 normalization reduce the excess mortality of active acromegaly to expected rates, cross-sectional data report some cardiovascular (cv) risk markers to be less favorable in remission than active acromegaly. |
2015-01-16 |
2023-08-13 |
Not clear |
Elisa Verrua, Emanuele Ferrante, Marcello Filopanti, Elena Malchiodi, Elisa Sala, Claudia Giavoli, Maura Arosio, Andrea Gerardo Lania, Cristina Lucia Ronchi, Giovanna Mantovani, Paolo Beck-Peccoz, Anna Spad. Reevaluation of Acromegalic Patients in Long-Term Remission according to Newly Proposed Consensus Criteria for Control of Disease. International journal of endocrinology. vol 2014. 2015-01-14. PMID:25587273. |
acromegaly guidelines updated in 2010 revisited criteria of disease control: if applied, it is likely that a percentage of patients previously considered as cured might present postglucose gh nadir levels not adequately suppressed, with potential implications on management. |
2015-01-14 |
2023-08-13 |
Not clear |
Esther Diaz-Rodriguez, Angela R Garcia-Rendueles, Alejandro Ibáñez-Costa, Ester Gutierrez-Pascual, Montserrat Garcia-Lavandeira, Alfonso Leal, Miguel A Japon, Alfonso Soto, Eva Venegas, Francisco J Tinahones, Juan A Garcia-Arnes, Pedro Benito, Maria Angeles Galvez, Luis Jimenez-Reina, Ignacio Bernabeu, Carlos Dieguez, Raul M Luque, Justo P Castaño, Clara V Alvare. Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF. Endocrinology. vol 155. issue 11. 2014-12-31. PMID:25137025. |
acromegaly is caused by somatotroph cell adenomas (somatotropinomas [acros]), which secrete gh. |
2014-12-31 |
2023-08-13 |
mouse |
Yuko Goto, Manabu Kinoshita, Satoru Oshino, Hideyuki Arita, Tetsuhiro Kitamura, Michio Otsuki, Iichiro Shimomura, Toshiki Yoshimine, Youichi Saito. Gsp mutation in acromegaly and its influence on TRH-induced paradoxical GH response. Clinical endocrinology. vol 80. issue 5. 2014-12-18. PMID:24111551. |
gsp mutation in acromegaly and its influence on trh-induced paradoxical gh response. |
2014-12-18 |
2023-08-12 |
Not clear |
Yuko Goto, Manabu Kinoshita, Satoru Oshino, Hideyuki Arita, Tetsuhiro Kitamura, Michio Otsuki, Iichiro Shimomura, Toshiki Yoshimine, Youichi Saito. Gsp mutation in acromegaly and its influence on TRH-induced paradoxical GH response. Clinical endocrinology. vol 80. issue 5. 2014-12-18. PMID:24111551. |
we recently reported that paradoxical gh response to trh administration reflects biological characteristics in patients with acromegaly. |
2014-12-18 |
2023-08-12 |
Not clear |
Irida Balili, Steven Sullivan, Paul Mckeever, Ariel Barka. Pituitary carcinoma with endolymphatic sac metastasis. Pituitary. vol 17. issue 3. 2014-12-16. PMID:23645293. |
a 15 year-old male was diagnosed in 1982 with a pituitary macroadenoma and acromegaly (random gh 67 ng/ml and no suppression by oral glucose). |
2014-12-16 |
2023-08-12 |
Not clear |
Lisa Sze, Marian C Neidert, René L Bernays, Cornelia Zwimpfer, Peter Wiesli, Sarah R Haile, Michael Brändle, Christoph Schmi. Gender dependence of serum soluble Klotho in acromegaly. Clinical endocrinology. vol 80. issue 6. 2014-12-15. PMID:24330426. |
in acromegaly, disease activity is biochemically assessed by growth hormone (gh) and insulin-like growth factor-1 (igf-1) levels. |
2014-12-15 |
2023-08-12 |
Not clear |
Lisa Sze, Marian C Neidert, René L Bernays, Cornelia Zwimpfer, Peter Wiesli, Sarah R Haile, Michael Brändle, Christoph Schmi. Gender dependence of serum soluble Klotho in acromegaly. Clinical endocrinology. vol 80. issue 6. 2014-12-15. PMID:24330426. |
to further elucidate the relationship between gh and skl, we examined the effect of gender on skl in patients with untreated acromegaly. |
2014-12-15 |
2023-08-12 |
Not clear |
Mariano Galdiero, Renata S Auriemma, Rosario Pivonello, Annamaria Cola. Cushing, acromegaly, GH deficiency and tendons. Muscles, ligaments and tendons journal. vol 4. issue 3. 2014-12-09. PMID:25489551. |
cushing, acromegaly, gh deficiency and tendons. |
2014-12-09 |
2023-08-13 |
Not clear |
Mariano Galdiero, Renata S Auriemma, Rosario Pivonello, Annamaria Cola. Cushing, acromegaly, GH deficiency and tendons. Muscles, ligaments and tendons journal. vol 4. issue 3. 2014-12-09. PMID:25489551. |
cushing's syndrome, induced by an endogenous or exogenous cortisol excess, and acromegaly, the clinical syndrome caused by growth hormone (gh) excess in adulthood, as well as the disease induced by gh deficiency (ghd), represent perfect models for the evaluation of the effects induced by chronic exposure in vivo, respectively, to cortisol and gh/igf-1 excess or deficiency on the complex structure of the tendons as well as on the related post-traumatic repair mechanism. |
2014-12-09 |
2023-08-13 |
Not clear |
Jason L Schroeder, Alejandro M Spiotta, Maria Fleseriu, Richard A Prayson, Amir H Hamrahian, Robert J Wei. Absence of immunostaining for growth hormone in a subset of patients with acromegaly. Pituitary. vol 17. issue 2. 2014-11-13. PMID:23475513. |
the presence of growth hormone (gh) immunostaining in patients who lack the biochemical and clinical features of acromegaly has been described. |
2014-11-13 |
2023-08-12 |
Not clear |
Jason L Schroeder, Alejandro M Spiotta, Maria Fleseriu, Richard A Prayson, Amir H Hamrahian, Robert J Wei. Absence of immunostaining for growth hormone in a subset of patients with acromegaly. Pituitary. vol 17. issue 2. 2014-11-13. PMID:23475513. |
in contrast, there is little information on the absence of gh immunostaining in patients with acromegaly. |
2014-11-13 |
2023-08-12 |
Not clear |
Jason L Schroeder, Alejandro M Spiotta, Maria Fleseriu, Richard A Prayson, Amir H Hamrahian, Robert J Wei. Absence of immunostaining for growth hormone in a subset of patients with acromegaly. Pituitary. vol 17. issue 2. 2014-11-13. PMID:23475513. |
we describe five patients with acromegaly with no intratumoral immunostaining for gh. |
2014-11-13 |
2023-08-12 |
Not clear |
Jason L Schroeder, Alejandro M Spiotta, Maria Fleseriu, Richard A Prayson, Amir H Hamrahian, Robert J Wei. Absence of immunostaining for growth hormone in a subset of patients with acromegaly. Pituitary. vol 17. issue 2. 2014-11-13. PMID:23475513. |
all patients had clinical features consistent with acromegaly and elevated baseline insulin-like growth factor-1 (igf-1) and gh. |
2014-11-13 |
2023-08-12 |
Not clear |
Jason L Schroeder, Alejandro M Spiotta, Maria Fleseriu, Richard A Prayson, Amir H Hamrahian, Robert J Wei. Absence of immunostaining for growth hormone in a subset of patients with acromegaly. Pituitary. vol 17. issue 2. 2014-11-13. PMID:23475513. |
gh immunostaining of an adenoma may not be sufficient to confirm the diagnosis of acromegaly. |
2014-11-13 |
2023-08-12 |
Not clear |
K Mori, Y Iwasaki, Y Kawasaki-Ogita, S Honjo, Y Hamamoto, H Tatsuoka, K Fujimoto, H Ikeda, Y Wada, Y Takahashi, J Takahashi, H Koshiyam. Improvement of insulin resistance following transsphenoidal surgery in patients with acromegaly: correlation with serum IGF-I levels. Journal of endocrinological investigation. vol 36. issue 10. 2014-11-13. PMID:23665535. |
the aim of this study was to determine the correlation between the growth hormone (gh)-insulin-like growth factor-i (igf-i) axis and glucose intolerance in acromegaly during the early postoperative period. |
2014-11-13 |
2023-08-12 |
Not clear |
Peter Kamenický, Gherardo Mazziotti, Marc Lombès, Andrea Giustina, Philippe Chanso. Growth hormone, insulin-like growth factor-1, and the kidney: pathophysiological and clinical implications. Endocrine reviews. vol 35. issue 2. 2014-11-10. PMID:24423979. |
it reports in particular new insights into the pathophysiological mechanism of body fluid retention and of changes in phospho-calcium metabolism in acromegaly as well as of the reciprocal changes in sodium, calcium, and phosphate homeostasis observed in gh deficiency. |
2014-11-10 |
2023-08-12 |
Not clear |
Kosma Wolinski, Agata Czarnywojtek, Marek Ruchal. Risk of thyroid nodular disease and thyroid cancer in patients with acromegaly--meta-analysis and systematic review. PloS one. vol 9. issue 2. 2014-10-21. PMID:24551163. |
acromegaly is a quite rare chronic disease caused by the increased secretion of growth hormone (gh) and subsequently insulin - like growth factor 1. |
2014-10-21 |
2023-08-12 |
Not clear |
Serkan Dogan, Aysegul Atmaca, Selcuk Dagdelen, Belkis Erbas, Tomris Erba. Evaluation of thyroid diseases and differentiated thyroid cancer in acromegalic patients. Endocrine. vol 45. issue 1. 2014-10-10. PMID:23670709. |
all available data for gender, age, body weight and height, duration of acromegaly, age at diagnosis of acromegaly, treatment methods for acromegaly and history of thyroid disease, serum gh, igf-1, thyroid function tests, thyroid ultrasonography (us), thyroid scintigraphy and thyroid fine needle aspiration biopsy (fnab) results were recorded for the patients. |
2014-10-10 |
2023-08-12 |
Not clear |