| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Boni Xiang, Xintong Zhang, Wenjuan Liu, Bei Mao, Yao Zhao, Yongfei Wang, Wei Gong, Hongying Ye, Yiming Li, Zhaoyun Zhang, Yifei Yu, Min H. Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort. Endocrine. 2024-06-08. PMID:38851643. |
germline aip variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a han chinese cohort. |
2024-06-08 |
2024-06-11 |
Not clear |
| Boni Xiang, Xintong Zhang, Wenjuan Liu, Bei Mao, Yao Zhao, Yongfei Wang, Wei Gong, Hongying Ye, Yiming Li, Zhaoyun Zhang, Yifei Yu, Min H. Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort. Endocrine. 2024-06-08. PMID:38851643. |
variants in the aryl hydrocarbon receptor-interacting protein (aip) gene have been identified in sporadic acromegaly and pituitary gigantism, especially in young patients, with a predisposition to aggressive clinical phenotype and poor treatment efficacy. |
2024-06-08 |
2024-06-11 |
Not clear |
| Boni Xiang, Xintong Zhang, Wenjuan Liu, Bei Mao, Yao Zhao, Yongfei Wang, Wei Gong, Hongying Ye, Yiming Li, Zhaoyun Zhang, Yifei Yu, Min H. Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort. Endocrine. 2024-06-08. PMID:38851643. |
the clinical characteristics of patients with sporadic acromegaly and pituitary gigantism as well as aip variants in han chinese have been rarely reported. |
2024-06-08 |
2024-06-11 |
Not clear |
| Boni Xiang, Xintong Zhang, Wenjuan Liu, Bei Mao, Yao Zhao, Yongfei Wang, Wei Gong, Hongying Ye, Yiming Li, Zhaoyun Zhang, Yifei Yu, Min H. Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort. Endocrine. 2024-06-08. PMID:38851643. |
we aimed to identify aip gene variants and analyze the clinical characteristics of patients with sporadic acromegaly and pituitary gigantism in han chinese. |
2024-06-08 |
2024-06-11 |
Not clear |
| Keren-Sandyn García-de-la-Torre, Jacobo Kerbel, Amayrani Cano-Zaragoza, Moisés Mercad. Atypical Course of a Patient With AIP-Positive Acromegaly: From GH Excess to GH Deficiency and Back to GH Excess. JCEM case reports. vol 1. issue 2. 2023-11-01. PMID:37908467. |
we herein present the complex case of a patient with acromegaly due to a mammosomatotrope adenoma, with a germ-line aip (aryl hydrocarbon receptor-interacting protein) mutation, who had a chronic and protracted course of more than 15 years during which he was treated with surgery, somatostatin receptor ligands, dopamine agonist, and the gh receptor antagonist pegvisomant. |
2023-11-01 |
2023-11-08 |
Not clear |
| M Detomas, B Altieri, J Flitsch, W Saeger, M Korbonits, T Deutschbei. Novel AIP mutation in exon 6 causing acromegaly in a German family. Journal of endocrinological investigation. 2023-02-09. PMID:36757586. |
novel aip mutation in exon 6 causing acromegaly in a german family. |
2023-02-09 |
2023-08-14 |
Not clear |
| M Detomas, B Altieri, J Flitsch, W Saeger, M Korbonits, T Deutschbei. Novel AIP mutation in exon 6 causing acromegaly in a German family. Journal of endocrinological investigation. 2023-02-09. PMID:36757586. |
here, we report a german family with two identical twins who were both affected by acromegaly and carried the above-mentioned novel aip mutation. |
2023-02-09 |
2023-08-14 |
Not clear |
| M Detomas, B Altieri, J Flitsch, W Saeger, M Korbonits, T Deutschbei. Novel AIP mutation in exon 6 causing acromegaly in a German family. Journal of endocrinological investigation. 2023-02-09. PMID:36757586. |
apart from reporting a novel aip mutation, this study does not only highlight the different clinical and histological features of the aip mutated growth hormone producing pituitary neuroendocrine tumors but also confirms the poor responsiveness of dopamine agonists in aip mutated acromegaly. |
2023-02-09 |
2023-08-14 |
Not clear |
| Amelia Rogozinski, Adrian F Daly, Adriana Reyes, Alejandra Furioso, Albert Beckers, Alicia Lowenstei. Differentiated thyroid carcinoma in sporadic and familial presentations of acromegaly: A case series. Annales d'endocrinologie. vol 81. issue 5. 2020-11-11. PMID:32822652. |
the most frequent inheritable form of acromegaly is related to germline mutations in the aryl hydrocarbon receptor interacting protein (aip) gene. |
2020-11-11 |
2023-08-13 |
Not clear |
| Marko Stojanovic, Zida Wu, Craig E Stiles, Dragana Miljic, Ivan Soldatovic, Sandra Pekic, Mirjana Doknic, Milan Petakov, Vera Popovic, Christian Strasburger, Márta Korbonit. Circulating aryl hydrocarbon receptor-interacting protein (AIP) is independent of GH secretion. Endocrine connections. vol 8. issue 4. 2020-09-28. PMID:30830858. |
we aimed to investigate possible aip and gh co-secretion, by studying serum aip and gh levels at baseline and after gh stimulation or suppression, in gh deficiency (ghd) and in acromegaly patients. |
2020-09-28 |
2023-08-13 |
Not clear |
| Adrian F Daly, Liliya Rostomyan, Daniela Betea, Jean-François Bonneville, Chiara Villa, Natalia S Pellegata, Beatrice Waser, Jean-Claude Reubi, Catherine Waeber Stephan, Emanuel Christ, Albert Becker. AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients. Endocrine connections. vol 8. issue 4. 2020-09-28. PMID:30851160. |
aryl hydrocarbon receptor interacting protein (aip) mutations are associated with an aggressive, inheritable form of acromegaly that responds poorly to sst2-specific somatostatin analogs (ssa). |
2020-09-28 |
2023-08-13 |
Not clear |
| Adrian F Daly, Liliya Rostomyan, Daniela Betea, Jean-François Bonneville, Chiara Villa, Natalia S Pellegata, Beatrice Waser, Jean-Claude Reubi, Catherine Waeber Stephan, Emanuel Christ, Albert Becker. AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients. Endocrine connections. vol 8. issue 4. 2020-09-28. PMID:30851160. |
we studied two aip mutation positive acromegaly patients with early-onset, invasive macroadenomas and inoperable residues after neurosurgery. |
2020-09-28 |
2023-08-13 |
Not clear |
| Adrian F Daly, Liliya Rostomyan, Daniela Betea, Jean-François Bonneville, Chiara Villa, Natalia S Pellegata, Beatrice Waser, Jean-Claude Reubi, Catherine Waeber Stephan, Emanuel Christ, Albert Becker. AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients. Endocrine connections. vol 8. issue 4. 2020-09-28. PMID:30851160. |
long-term pasireotide lar therapy can be beneficial in some aip mutation positive acromegaly patients that are resistant to first-generation ssa. |
2020-09-28 |
2023-08-13 |
Not clear |
| Adrian F Daly, Jean-François Vanbellinghen, Albert Becker. Characteristics of familial isolated pituitary adenomas. Expert review of endocrinology & metabolism. vol 2. issue 6. 2019-11-20. PMID:30290472. |
while very infrequent in sporadic pituitary tumors, approximately 15% of fipa patients have aip mutations, rising to half of patients with familial acromegaly. |
2019-11-20 |
2023-08-13 |
Not clear |
| Hande Mefkure Ozkaya, Nil Comunoglu, Muge Sayitoglu, Fatma Ela Keskin, Sinem Firtina, Khusan Khodzhaev, Tugce Apaydin, Nurperi Gazioglu, Necmettin Tanriover, Buge Oz, Pinar Kadiogl. Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues. Pituitary. vol 21. issue 4. 2018-10-16. PMID:29455389. |
germline mutations of aryl hydrocarbon receptor-interacting protein (aip) gene and somatostatin receptor 1-5 and aip immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues. |
2018-10-16 |
2023-08-13 |
Not clear |
| Hande Mefkure Ozkaya, Nil Comunoglu, Muge Sayitoglu, Fatma Ela Keskin, Sinem Firtina, Khusan Khodzhaev, Tugce Apaydin, Nurperi Gazioglu, Necmettin Tanriover, Buge Oz, Pinar Kadiogl. Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues. Pituitary. vol 21. issue 4. 2018-10-16. PMID:29455389. |
to determine aryl hydrocarbon interacting protein (aip) gene variations and aip and somatostatin receptor (sstr) 1-5 immunostaining in patients with apparently sporadic acromegaly with poor versus good response to somatostatin analogues (srls). |
2018-10-16 |
2023-08-13 |
Not clear |
| Liliya Rostomyan, Iulia Potorac, Pablo Beckers, Adrian F Daly, Albert Becker. AIP mutations and gigantism. Annales d'endocrinologie. vol 78. issue 2. 2018-03-19. PMID:28483363. |
aip mutations are rare in sporadic acromegaly but they are seen at a higher frequency among certain specific populations of pituitary adenoma patients (pituitary gigantism cases, familial isolated pituitary adenoma (fipa) kindreds, and patients with macroadenomas who are diagnosed ≤30 years). |
2018-03-19 |
2023-08-13 |
Not clear |
| C J Scudder, S J Niessen, B Catchpole, R C Fowkes, D B Church, Y Forcad. Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene. Domestic animal endocrinology. vol 59. 2017-12-19. PMID:28119176. |
feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the aip gene. |
2017-12-19 |
2023-08-13 |
human |
| C J Scudder, S J Niessen, B Catchpole, R C Fowkes, D B Church, Y Forcad. Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene. Domestic animal endocrinology. vol 59. 2017-12-19. PMID:28119176. |
acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (aip) gene. |
2017-12-19 |
2023-08-13 |
human |
| C J Scudder, S J Niessen, B Catchpole, R C Fowkes, D B Church, Y Forcad. Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene. Domestic animal endocrinology. vol 59. 2017-12-19. PMID:28119176. |
feline acromegaly has similarities to human acromegalic families with aip mutations. |
2017-12-19 |
2023-08-13 |
human |