| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irmak Yaldız Koç, Merih Beler, İsmail Ünal, Selçuk Paker, Ebru Emekli-Alturfan, A Ata Alturfan, Derya Cansı. Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics. The Science of the total environment. 2024-09-08. PMID:39245375. |
we found decreased mrna transcript abundance of lepa, ins, pparg, and activities of superoxide dismutase and acetylcholine esterase, along with increased lipid peroxidation (lpo), nitric oxide (no), and glutathione s-transferase (gst). |
2024-09-08 |
2024-09-11 |
zebrafish |
| Zeliha Bayram, Esra Akcabag, Gul Ozbey, Cahit Nacitarhan, Sebahat Ozdem, Cengiz Turkay, Sadi S Ozde. THE effect of P2X7 receptor activation on functional responses of human left internal mammary artery. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-03. PMID:39225832. |
long-term (60 min) incubation with specific p2x7r agonist bz-atp caused significant reductions in relaxation responses of lima to atp and acetylcholine, which were reversed by selective p2x7r antagonists brilliant blue g or az11645373, whereas there were no changes in relaxation responses to endothelium-independent vasodilators isoprenaline, camp analog 8-br-camp, and nitric oxide donor sodium nitroprusside. |
2024-09-03 |
2024-09-05 |
human |
| Ravina Rai, Pankaj Lal Kalar, Deepali Jat, Siddhartha Kumar Mishr. Naringenin Mitigates Nanoparticulate-Aluminium Induced Neuronal Degeneration in Brain Cortex and Hippocampus through Downregulation of Oxidative Stress and Neuroinflammation. Neurochemistry international. 2024-07-01. PMID:38950625. |
we measured nitric oxide, advanced oxidation of protein products, protein carbonylation, lipid peroxidation, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, reduced glutathione, oxidised glutathione, and acetylcholine esterase, as well as cytokines analysis, immunohistochemistry, and dna damage. |
2024-07-01 |
2024-07-04 |
mouse |
| Mehmet Öz, Hüseyin Erda. A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and neuroinflammation. Behavioural brain research. 2024-04-10. PMID:38599251. |
a tnf-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, bdnf release, and neuroinflammation. |
2024-04-10 |
2024-04-13 |
mouse |
| Michał Majewski, Leszek Gromadziński, Ewelina Cholewińska, Katarzyna Ognik, Bartosz Fotschki, Jerzy Juśkiewic. Dietary Effects of Chromium Picolinate and Chromium Nanoparticles in Wistar Rats Fed with a High-Fat, Low-Fiber Diet: The Role of Fat Normalization. Nutrients. vol 14. issue 23. 2022-12-11. PMID:36501167. |
in the intervention group, both cr-pic and cr-nps decreased heart glutathione ratio (gsh+gssg), enhanced participation of nitric oxide (no) derived from inducible no synthase (inos) in vascular relaxation to acetylcholine (ach), increased the vasodilator net effect of cyclooxygenase-2 (cox-2)-derived prostanoids, and increased the production of superoxide anion (o |
2022-12-11 |
2023-08-14 |
rat |
| Catherine M Davis, Kristin Lyon-Scott, Elena V Varlamov, Wenri H Zhang, Nabil J Alkaye. Role of Endothelial STAT3 in Cerebrovascular Function and Protection from Ischemic Brain Injury. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293020. |
the sub-lethal inhibition of stat3 caused endothelial dysfunction, demonstrated by reduced nitric oxide release in response to acetylcholine and reduced barrier function of the endothelial monolayer. |
2022-10-27 |
2023-08-14 |
mouse |
| Gamze Bayrak, Ismet Burcu Turkyilmaz, Refiye Yanarda. The protective effect of vitamin U on pentylenetetrazole-induced brain damage in rats. Journal of biochemical and molecular toxicology. 2022-07-14. PMID:35833322. |
in the ptz group, glutathione and lipid peroxidation levels, alkaline phosphatase, myeloperoxidase, xanthine oxidase, acetylcholine esterase, antioxidant enzyme activities, total oxidant status, oxidative stress index, reactive oxygen species, and nitric oxide levels were increased. |
2022-07-14 |
2023-08-14 |
rat |
| Catia Sternini, Luis Cabanillas, Maurizio Mazzoni, Filippo Caremoli, Million Mulugeta, Muriel Larauche, Paolo Clavenzani, Roberto De Giorgi. Neurochemical Profile of Enteric Neurons in the Submucosal Plexuses of Pig vs. Human Colon. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557063. |
we have previously shown that in the adult pig colon, the density of enteric neurons is significantly higher in the isp than osp in ascending (ac) and descending (dc) colon, and that neurons in both plexuses contain choline acetyltransferase (chat) immunoreactivity (ir) and neuronal nitric oxide synthase (nnos)-ir, markers of the major excitatory (acetylcholine) and inhibitory (nitric oxide) transmitters with a small subpopulation containing both transmitters (cell tissue res. |
2022-05-13 |
2023-08-13 |
human |
| Congying Chen, Lingling Bu, Huan Liu, Yifeng Rang, Huiying Huang, Xueman Xiao, Genghua Ou, Chunhong Li. Learning and memory impairment induced by 1,4-butanediol is regulated by ERK1/2-CREB-BDNF signaling pathways in PC12 cells. Metabolic brain disease. 2022-03-29. PMID:35348994. |
assay kits results showed that 1,4-bd decreased the levels of glutathione (gsh), glutathione peroxidase (gsh-px), superoxide dismutase (sod), acetylcholine (ach) and increased the levels of malondialdehyde (mda), nitric oxide (no) and acetylcholinesterase (ache). |
2022-03-29 |
2023-08-13 |
Not clear |
| Amina E Essawy, Soad Ahmed El-Sayed, Ehab Tousson, Horeya S Abd El-Gawad, Reem Hasaballah Alhasani, Heba-Tallah Abd Elrahim Abd Elkade. Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy. Environmental science and pollution research international. 2022-02-23. PMID:35194715. |
the oxidative stress, antioxidant, and neurochemical parameters, viz., malondialdehyde (mda), nitric oxide (no), reduced glutathione (gsh), superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), acetylcholine esterase (ache), dopamine (da), norepinephrine (ne), and serotonin (5-ht), in the hippocampal and hypothalamic regions have been evaluated. |
2022-02-23 |
2023-08-13 |
rat |
| Mohammad Reza Safdari, Farzaneh Shakeri, Ameneh Mohammadi, Bahram Bibak, Peiman Alesheikh, Tannaz Jamialahmadi, Thozhukat Sathyapalan, Amirhossein Sahebka. Role of Herbal Medicines in the Management of Brain Injury. Advances in experimental medicine and biology. vol 1328. 2022-01-04. PMID:34981485. |
the different mechanisms for improvement in brain injury by these medicinal plants include hif-1 (hypoxia-inducible factor 1) signaling, free-radical scavenging, reduction of nitric oxide (no) toxicity and acetylcholine esterase (ache) activity, decrease of pakt and its downstream targets, downregulation of the aquaporin-4 (aqp-4) and tlr4/nf-ĸb/tnf-α signal, reduction in malondialdehyde and no levels, increasing neuronal density in the hippocampus, and inhibition of oxidative stress. |
2022-01-04 |
2023-08-13 |
Not clear |
| Asami Mori, Daiki Sumida, Ryo Kondo, Ayuki Nakano, Shiho Arima, Daiki Asano, Akane Morita, Kenji Sakamoto, Tohru Nagamitsu, Tsutomu Nakahar. Impairment of endothelium-dependent vasodilator function of retinal blood vessels in adult rats with a history of retinopathy of prematurity. Journal of pharmacological sciences. vol 146. issue 4. 2021-11-12. PMID:34116737. |
on p56, vasodilator responses to acetylcholine, gsk1016790a (an activator of transient receptor potential vanilloid 4 channels), nor3 (a nitric oxide [no] donor), and salbutamol (a β |
2021-11-12 |
2023-08-13 |
rat |
| Katarzyna Szadujkis-Szadurska, Grzegorz Grzesk, Leszek Szadujkis-Szadurski, Marta Gajdus, Grzegorz Matusia. Role of acetylcholine and calcium ions in three vascular contraction models: Angiotensin II, phenylephrine and caffeine. Experimental and therapeutic medicine. vol 4. issue 2. 2021-10-21. PMID:22984369. |
the spasmolytic effect of acetylcholine on responses stimulated by ang ii and phe indicates the participation of nitric oxide in modulating the reactivity of the arteries on the studied agonists of the metabotropic receptors. |
2021-10-21 |
2023-08-12 |
rat |
| Baoli Li, Lu Wang, Yongxian Liu, Yahui Chen, Zhengxiang Zhang, Jing Zhan. Jujube promotes learning and memory in a rat model by increasing estrogen levels in the blood and nitric oxide and acetylcholine levels in the brain. Experimental and therapeutic medicine. vol 5. issue 6. 2021-10-21. PMID:23837068. |
jujube promotes learning and memory in a rat model by increasing estrogen levels in the blood and nitric oxide and acetylcholine levels in the brain. |
2021-10-21 |
2023-08-12 |
rat |
| Javier Palacios, Julio Benites, Gareth I Owen, Pablo Morales, Mario Chiong, Chukwuemeka R Nwokocha, Adrián Paredes, Fredi Cifuente. Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism. Journal of cardiovascular pharmacology. vol 77. issue 2. 2021-07-09. PMID:33105322. |
in exvivo experiments with aortic rings precontracted with phenylephrine (pe, 10-6 m), q7 (10-5 m) significantly (p < 0.05) reduced vascular rhythmic contractions induced by the acetylcholine (ach; 10-7-10-5 m), whereas sodium nitroprusside (a nitric oxide donor; 10-8 m) recovered the vasomotion. |
2021-07-09 |
2023-08-13 |
Not clear |
| Nilson Carlos Ferreira-Junior, Davi Campos Lagatta, Luciana Bärg Kuntze, Eduardo Akira Fujiwara, Egidi Mayara Silva Firmino, Anna Bárbara Borges-Assis, Leonardo Barbosa Moraes Resstel, Karla Nívea Sampai. Dorsal hippocampus cholinergic and nitrergic neurotransmission modulates the cardiac baroreflex function in rats. The European journal of neuroscience. vol 51. issue 4. 2021-06-21. PMID:31626713. |
hippocampal muscarinic receptors activation by acetylcholine might evoke nitric oxide synthesis, which is an important neuromodulator of cardiovascular responses. |
2021-06-21 |
2023-08-13 |
rat |
| Asmaa F Khafaga, Sara E El-Kazaz, Ahmed E Noreldi. Boswellia serrata suppress fipronil-induced neuronal necrosis and neurobehavioral alterations via promoted inhibition of oxidative/inflammatory/apoptotic pathways. The Science of the total environment. vol 785. 2021-06-10. PMID:33933775. |
results revealed that co-treatment with bse led to significant (p > 0.05) dose-dependent reduction in malondialdehyde (mda), nitric oxide (no), interleukin-6 (il6), tumor necrosis factors-alpha (tnf-α), nuclear factor kappa-b (nf-κb), cyclooxegenase-2 (cox-2), prostaglandin e2 (pge2), serotonin, and acetylcholine (ach). |
2021-06-10 |
2023-08-13 |
rat |
| Tao Li, Qiaojuan Yan, Yongping Wen, Jun Liu, Jian Sun, Zhengqiang Jian. Synbiotic yogurt containing konjac mannan oligosaccharides and Bifidobacterium animalis ssp. lactis BB12 alleviates constipation in mice by modulating the stem cell factor (SCF)/c-Kit pathway and gut microbiota. Journal of dairy science. vol 104. issue 5. 2021-04-26. PMID:33663840. |
serum levels of excitability neurotransmitters (motilin, substance p, and acetylcholine) in the ybk2.0 group were increased by 139.7, 120.4, and 91.8%, respectively, and serum levels of inhibitory neurotransmitters (vasoactive intestinal peptide, nitric oxide, and acetylcholine) were decreased. |
2021-04-26 |
2023-08-13 |
mouse |
| Dong-Qin Zhao, Hua Xue, Hai-Ji Su. Nervous mechanisms of restraint water-immersion stress-induced gastric mucosal lesion. World journal of gastroenterology. vol 26. issue 20. 2021-03-31. PMID:32523309. |
neurotransmitters/neuromodulators, such as nitric oxide, hydrogen sulfide, vasoactive intestinal peptide, calcitonin gene-related peptide, substance p, enkephalin, 5-hydroxytryptamine, acetylcholine, catecholamine, glutamate, γ-aminobutyric acid, oxytocin and arginine vasopressin, can participate in the regulation of stress. |
2021-03-31 |
2023-08-13 |
Not clear |
| Omowumi T Kayode, Damilare E Rotimi, Tomilola D Olaolu, Oluyomi Stephen Adeyem. Ketogenic diet improves and restores redox status and biochemical indices in monosodium glutamate-induced rat testicular toxicity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 127. 2021-02-11. PMID:32434144. |
in the pre-treatment, the administration of msg resulted in a significant (p < 0.05) decrease in the testis-body weight ratio, alkaline phosphatase (alp), acetylcholine esterase (ache), cholesterol, triglycerides (tg), nitric oxide (no), glycogen, protein and antioxidant enzymes in the testis. |
2021-02-11 |
2023-08-13 |
rat |