| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Özge Türkoğlu, Aygün Ertuğru. The Role of Cannabis in the Development of Psychosis. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 35. issue 3. 2024-09-03. PMID:39224996. |
studies showed that the endocannabinoid system, which plays a role in nervous system development and functions as a homeostatic regulator in physiological processes, is affected by cannabis use during critical periods of development like adolescence; cannabis use affects physiological processes such as synaptic pruning due to the effects of this system on neurotransmitters like glutamate and dopamine leading to long-term behavioral and psychological consequences. |
2024-09-03 |
2024-09-05 |
Not clear |
| Kawsar U Chowdhury, Madison Elizabeth Holden, Miles T Wiley, Vishnu Suppiramaniam, Miranda N Ree. Effects of Cannabis on Glutamatergic Neurotransmission: The Interplay between Cannabinoids and Glutamate. Cells. vol 13. issue 13. 2024-07-12. PMID:38994982. |
effects of cannabis on glutamatergic neurotransmission: the interplay between cannabinoids and glutamate. |
2024-07-12 |
2024-07-14 |
Not clear |
| Sarah Al Sharie, Scott J Varga, Lou'i Al-Husinat, Piercarlo Sarzi-Puttini, Mohammad Araydah, Batool Riyad Bal'awi, Giustino Varrass. Unraveling the Complex Web of Fibromyalgia: A Narrative Review. Medicina (Kaunas, Lithuania). vol 60. issue 2. 2024-02-24. PMID:38399559. |
this study also delves into emerging research, exploring advances in neurobiological understanding, brain imaging, genetic markers, glutamate modulation, cannabinoids, gut microbiome, and digital health tools for fibromyalgia management. |
2024-02-24 |
2024-02-26 |
Not clear |
| Dora Steel, Kimberley M Reid, Antonio Pisani, Ellen J Hess, Susan Fox, Manju A Kuria. Advances in targeting neurotransmitter systems in dystonia. International review of neurobiology. vol 169. 2023-07-23. PMID:37482394. |
in this chapter we discuss the physiology of key neurotransmitters, including dopamine, noradrenaline, serotonin (5-hydroxytryptamine), acetylcholine, gaba, glutamate, adenosine and cannabinoids, and their role in dystonia. |
2023-07-23 |
2023-08-14 |
Not clear |
| A Alhowail, M Aldubaya. Mechanisms underlying cognitive impairment induced by prenatal cannabinoid exposure: a literature review. European review for medical and pharmacological sciences. vol 27. issue 11. 2023-06-15. PMID:37318470. |
the findings from the studies reviewed revealed that the cognitive impairment associated with prenatal cannabinoid exposure is caused by alterations in the expression and function of endocannabinoid receptor 1 (cb1r), decreased glutamate transmission, reduced neurogenesis, alterations in protein kinase b (pkb/akt) and extracellular signal‑regulated kinase 1 and 2 (erk1/2) activity, and increased mitochondrial function in the hippocampus, cortex, and cerebellum. |
2023-06-15 |
2023-08-14 |
human |
| Peng Chen, Chen Wang, Qian Gong, Yihui Chai, Yunzhi Chen, Cuiwen Song, Yuanhua Wu, Long Wan. Alterations of endogenous pain-modulatory system of the cerebral cortex in the neuropathic pain. iScience. vol 26. issue 5. 2023-05-11. PMID:37168579. |
integrative analyses showed that the differentially expressed metabolites and proteins were primarily involved in alanine, aspartate and glutamate metabolism, gabaergic synapse, and retrograde endocannabinoid signaling. |
2023-05-11 |
2023-08-14 |
Not clear |
| Isaac Ostlund, Michael Von Gunten, Calvin Smith, Jeffrey G Edward. Chronic Δ9-tetrahydrocannabinol impact on plasticity, and differential activation requirement for CB1-dependent long-term depression in ventral tegmental area GABA neurons in adult versus young mice. Frontiers in neuroscience. vol 16. 2023-01-26. PMID:36699526. |
in young mice, vta gaba cells exhibit a form of synaptic plasticity known as long-term depression (ltd) that is dependent on cannabinoid 1 (cb1) receptors preceded by metabotropic glutamate receptor 5 (mglur5) signaling to induce endocannabinoid production. |
2023-01-26 |
2023-08-14 |
mouse |
| Nicolas Singewald, Simone B Sartori, Andreas Reif, Andrew Holme. Alleviating anxiety and taming trauma: Novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder. Neuropharmacology. 2023-01-09. PMID:36623804. |
the evaluation of putative treatments targeting monoamine (including psychedelics), gaba, glutamate, cannabinoid, cholinergic and neuropeptide systems, amongst others, are discussed. |
2023-01-09 |
2023-08-14 |
Not clear |
| Ying Chen, Yuhan Liu, Yine Song, Shaoru Zhao, Bin Li, Jingqing Sun, Lu Li. Therapeutic applications and potential mechanisms of acupuncture in migraine: A literature review and perspectives. Frontiers in neuroscience. vol 16. 2022-11-07. PMID:36340786. |
in addition, acupuncture participates in the development of peripheral and central sensitization through modulation of the release of neuronal-sensitization-related mediators (brain-derived neurotrophic factor, glutamate), endocannabinoid system, and serotonin system activation. |
2022-11-07 |
2023-08-14 |
human |
| Jeremy J Watts, Elisa Guma, Sofia Chavez, Rachel F Tyndale, Ruth A Ross, Sylvain Houle, Alan A Wilson, Mallar Chakravarty, Pablo M Rusjan, Romina Mizrah. In vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with PET, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-07-29. PMID:35906490. |
in vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with pet, dysregulation of hippocampus glutamatergic neurotransmission and reductions in hippocampal volume have been associated with psychiatric disorders. |
2022-07-29 |
2023-08-14 |
Not clear |
| Jeremy J Watts, Elisa Guma, Sofia Chavez, Rachel F Tyndale, Ruth A Ross, Sylvain Houle, Alan A Wilson, Mallar Chakravarty, Pablo M Rusjan, Romina Mizrah. In vivo brain endocannabinoid metabolism is related to hippocampus glutamate and structure - a multimodal imaging study with PET, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-07-29. PMID:35906490. |
the endocannabinoid system modulates glutamate neurotransmission and brain development, including hippocampal remodeling. |
2022-07-29 |
2023-08-14 |
Not clear |
| Daniela Monje-Reyna, Jorge Manzo Denes, Fidel Santamari. Effects of environmental enrichment and sexual dimorphism on the expression of cerebellar receptors in C57BL/6 and BTBR + Itpr3tf/J mice. BMC research notes. vol 15. issue 1. 2022-05-13. PMID:35562810. |
we compared the effects of environmental enrichment in the expression of glutamate and endocannabinoid receptors, which are widely expressed in the cerebellar cortex. |
2022-05-13 |
2023-08-13 |
mouse |
| Gregory G Grecco, Braulio Muñoz, Gonzalo Viana Di Prisco, Emma H Doud, Brandon M Fritz, Danielle Maulucci, Yong Gao, Amber L Mosley, Anthony J Baucum, Brady K Atwoo. Prenatal opioid exposure impairs endocannabinoid and glutamate transmission in the dorsal striatum. eNeuro. 2022-04-09. PMID:35396255. |
prenatal opioid exposure impairs endocannabinoid and glutamate transmission in the dorsal striatum. |
2022-04-09 |
2023-08-13 |
mouse |
| Gregory G Grecco, Braulio Muñoz, Gonzalo Viana Di Prisco, Emma H Doud, Brandon M Fritz, Danielle Maulucci, Yong Gao, Amber L Mosley, Anthony J Baucum, Brady K Atwoo. Prenatal opioid exposure impairs endocannabinoid and glutamate transmission in the dorsal striatum. eNeuro. 2022-04-09. PMID:35396255. |
we previously demonstrated that opioids have deleterious effects on endocannabinoid plasticity at glutamate synapses in the dorsal striatum of adolescent rodents, but it is unclear if prenatal opioid exposure produces similar neuroadaptations. |
2022-04-09 |
2023-08-13 |
mouse |
| Davin R Peart, Allyson K Andrade, Carly N Logan, Lori A Knackstedt, Jennifer E Murra. Regulation of Cocaine-related Behaviors by Estrogen and Progesterone. Neuroscience and biobehavioral reviews. 2022-02-21. PMID:35189163. |
these opposing effects of 17ß-estradiol and progesterone/allopregnanolone involve endocannabinoid, γ-aminobutyric acid, dopamine, and glutamate transmission in the medial prefrontal cortex and striatum. |
2022-02-21 |
2023-08-13 |
rat |
| Chun S Zuo, Katherine A Davis, Madeline K Kuppe, M Kathryn Dahlgren, Staci Gruber, Garrett M Fitzmaurice, Scott E Luka. Elevated striatal glutamate + glutamine in recreational cannabis users during abstinence. Journal of psychiatric research. vol 146. 2022-01-09. PMID:34999370. |
we hypothesize that cannabis withdrawal may be associated with a reset of regional γ-amino butyric acid (gaba) and glutamate concentrations secondary to changes in the endocannabinoid system during abstinence and conducted a study on this issue. |
2022-01-09 |
2023-08-13 |
human |
| Pan Zhang, Olivia C Perez, Bruce R Southey, Jonathan V Sweedler, Amynah A Pradhan, Sandra L Rodriguez-Za. Alternative Splicing Mechanisms Underlying Opioid-Induced Hyperalgesia. Genes. vol 12. issue 10. 2021-12-03. PMID:34680965. |
splicing of genes in the gonadotropin-releasing hormone receptor pathway was detected in the nucleus accumbens while splicing in the vascular endothelial growth factor, endogenous cannabinoid signaling, circadian clock system, and metabotropic glutamate receptor pathways was detected in the trigeminal ganglia. |
2021-12-03 |
2023-08-13 |
mouse |
| Aren van Waarde, Sofia Marcolini, Peter Paul de Deyn, Rudi A J O Dierck. PET Agents in Dementia: An Overview. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33500121. |
many receptors belong to this category: ampa, cannabinoid, colony stimulating factor 1, metabotropic glutamate receptor 1 and 5 (mglur1, mglur5), opioid (kappa, mu), purinergic (p2x7, p2y12), sigma-1, sigma-2, receptor for advanced glycation endproducts, and triggering receptor expressed on myeloid cells-1, besides several enzymes: cyclooxygenase-1 and 2 (cox-1, cox-2), phosphodiesterase-5 and 10 (pde5, pde10), and tropomyosin receptor kinase. |
2021-12-02 |
2023-08-13 |
Not clear |
| Marta Kruk-Slomka, Grazyna Bial. Cannabidiol Attenuates MK-801-Induced Cognitive Symptoms of Schizophrenia in the Passive Avoidance Test in Mice. Molecules (Basel, Switzerland). vol 26. issue 19. 2021-11-18. PMID:34641522. |
the present findings confirm that cbd has a positive influence on memory and learning processes in mice, and reveals that this cannabinoid compound is able to attenuate memory impairment connected with hypofunction of glutamate transmission in a murine model of schizophrenia. |
2021-11-18 |
2023-08-13 |
mouse |
| Tomoteru Yamasaki, Akiko Hatori, Yiding Zhang, Wakana Mori, Yusuke Kurihara, Masanao Ogawa, Hidekatsu Wakizaka, Jian Rong, Lu Wang, Steven Liang, Ming-Rong Zhan. Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study. Theranostics. vol 11. issue 19. 2021-10-15. PMID:34646382. |
monoacylglycerol lipase (magl) is a modulator of 2-arachidonoylglycerol (2-ag), which is involved in retrograde inhibition of glutamate release in the endocannabinoid system. |
2021-10-15 |
2023-08-13 |
rat |