| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie An, Inna Astapova, Guofang Zhang, Andrew L Cangelosi, Olga Ilkayeva, Hannah Marchuk, Michael J Muehlbauer, Tabitha George, Joseph Brozinick, Mark A Herman, Christopher B Newgar. Integration of metabolomic and transcriptomic analyses reveals novel regulatory functions of the ChREBP transcription factor in energy metabolism. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345566. |
the drop in free coa levels, needed for the 2-ketoglutarate dehydrogenase reaction, as well as a decrease in transcripts encoding the anaplerotic enzymes pyruvate carboxylase, glutamate dehydrogenase, and aspartate transaminase likely contributed to these effects. |
2024-09-30 |
2024-10-02 |
rat |
| Jian Tan, Huiying Zhao, Liuxue Li, Ying Wang, Yucong Pan, Luoyun Fang, Yuchao Zhao, Linshu Jian. Propylene Glycol Alleviates Oxidative Stress and Enhances Immunity in Ketotic Cows through Modulating Amino Acid and Lipid Metabolism. Antioxidants (Basel, Switzerland). vol 13. issue 9. 2024-09-28. PMID:39334805. |
a pathway analysis indicated that prg affects multiple metabolic pathways, including alanine, aspartate, glutamate metabolism, and sphingolipid metabolism. |
2024-09-28 |
2024-10-01 |
Not clear |
| Doru Morar, Cristina Văduva, Adriana Morar, Mirela Imre, Camelia Tulcan, Kálmán Imr. Paraclinical Changes Occurring in Dairy Cows with Spontaneous Subacute Ruminal Acidosis under Field Conditions. Animals : an open access journal from MDPI. vol 12. issue 18. 2024-09-04. PMID:36139324. |
serum aspartate aminotransferase (ast) and glutamate dehydrogenase (gldh) activity were significantly higher in the sara cows (p < 0.05) than in the group of healthy cows. |
2024-09-04 |
2024-09-06 |
Not clear |
| Fei Ren, Jinji Lin, Mengxu Zhu, Rui Ma, Ming Zhang, Weijun Chen, Guobiao Ma, Haiming Chen, Rongrong He, Wenxue Che. Polysaccharides from Alpinia oxyphylla fruit prevent hyperuricemia by inhibiting uric acid synthesis, modulating intestinal flora and reducing renal inflammation. International journal of biological macromolecules. 2024-08-16. PMID:39151857. |
afp inhibited ua synthesis by regulating pyrimidine metabolism and the metabolism of alanine, aspartate and glutamate, reduced kidney inflammation, and promoted ua excretion by regulating intestinal flora. |
2024-08-16 |
2024-08-20 |
mouse |
| Zhou Sha, Stephen J Benkovi. Purinosomes spatially co-localize with mitochondrial transporters. The Journal of biological chemistry. 2024-08-04. PMID:39098527. |
here, we propose that the purinosome is located proximally to the mitochondrial transporters slc25a13 and slc25a38, facilitating the uptake of glycine, aspartate, and glutamate, essential factors for purine synthesis. |
2024-08-04 |
2024-08-07 |
Not clear |
| Qiuyu Lan, Ana Cristina De Aguiar Saldanha Pinheiro, Giacomo Braschi, Gianfranco Picone, Pietro Rocculi, Luca Lagh. Integrated metabolomics analysis of chill-stored rose shrimp (Parapenaeus longirostris) treated with different pressure levels of high hydrostatic pressure by Journal of food science. 2024-08-04. PMID:39098810. |
metabolic pathway analysis revealed several pathways underlying spoilage, including pyruvate metabolism, valine, leucine, and isoleucine biosynthesis, purine metabolism, methane metabolism, glycine, serine, and threonine metabolism, citrate cycle (tca cycle), glycolysis/gluconeogenesis, alanine, aspartate, and glutamate metabolism, sulfur metabolism, pantothenate and coa biosynthesis, glutathione metabolism, and glyoxylate and dicarboxylate metabolism. |
2024-08-04 |
2024-08-07 |
Not clear |
| Xian-Xi Ye, Qiao-Ying Jiang, Meng-Jun Wu, Qing-Huai Ye, Hong Zhen. Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation. Acta pharmacologica Sinica. 2024-07-11. PMID:38992120. |
fmt also reshaped the metabolic phenotypes in the hippocampus of t1d mice especially for alanine, aspartate and glutamate metabolism. |
2024-07-11 |
2024-07-14 |
mouse |
| Rocío Del Carmen Bravo-Miana, Jone Karmele Arizaga-Echebarria, David Otaegu. Central nervous system-derived extracellular vesicles: the next generation of neural circulating biomarkers? Translational neurodegeneration. vol 13. issue 1. 2024-06-20. PMID:38898538. |
in this sense, other surface biomarkers for cns-derived evs, such as glutamate aspartate transporter (glast) and myelin oligodendrocyte glycoprotein (mog), among others, have started to be used. |
2024-06-20 |
2024-06-22 |
Not clear |
| Timea Forró, Doina Ramona Manu, Ovidiu-Lucian Băjenaru, Rodica Bălaș. GFAP as Astrocyte-Derived Extracellular Vesicle Cargo in Acute Ischemic Stroke Patients-A Pilot Study. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891912. |
subsets of presumed adevs were identified further by the expression of the glutamate aspartate transporter (glast) as a specific marker of astrocytes with the basic exo-flow capture kit. |
2024-06-19 |
2024-06-21 |
Not clear |
| Wenfeng Yang, Pan Gao, Zongda Ye, Funing Chen, Liandong Zh. Micro/nano-plastics and microalgae in aquatic environment: Influence factor, interaction, and molecular mechanisms. The Science of the total environment. vol 934. 2024-05-21. PMID:38761949. |
besides, algae resisted this inhibitory effect by regulating the alanine, aspartate, and glutamate metabolism and purine metabolism pathways, thereby increasing the chlorophyll synthesis, inhibiting the increase of reactive oxygen species, delaying the process of lipid peroxidation, balancing the osmotic pressure of cell membrane. |
2024-05-21 |
2024-05-27 |
Not clear |
| b' Edoardo Jos\\xc3\\xa9 Longarini, Ivan Mati\\xc4\\x8. Preserving ester-linked modifications reveals glutamate and aspartate mono-ADP-ribosylation by PARP1 and its reversal by PARG. Nature communications. vol 15. issue 1. 2024-05-18. PMID:38762517.' |
preserving ester-linked modifications reveals glutamate and aspartate mono-adp-ribosylation by parp1 and its reversal by parg. |
2024-05-18 |
2024-05-27 |
Not clear |
| b' Edoardo Jos\\xc3\\xa9 Longarini, Ivan Mati\\xc4\\x8. Preserving ester-linked modifications reveals glutamate and aspartate mono-ADP-ribosylation by PARP1 and its reversal by PARG. Nature communications. vol 15. issue 1. 2024-05-18. PMID:38762517.' |
this is the case even for long-known modifications, such as adp-ribosylation on aspartate and glutamate, whose role in parp1 signaling has recently been questioned. |
2024-05-18 |
2024-05-27 |
Not clear |
| Ji Hye Kim, Jinyoung Lee, Se Seul Im, Boyun Kim, Eun-Young Kim, Hyo-Jin Min, Jinbeom Heo, Eun-Ju Chang, Kyung-Chul Choi, Dong-Myung Shin, Jaekyoung So. Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer. Experimental & molecular medicine. vol 56. issue 4. 2024-04-29. PMID:38684915. |
knockdown of glutamic-oxaloacetic transaminase 2, which facilitates the conversion of oxaloacetate and glutamate into aspartate and akg, decreased akg production and the cflip level and activated trail-induced apoptosis. |
2024-04-29 |
2024-05-03 |
Not clear |
| Fatma Subaşı Turgut, Mahmut Bulut, Salih Hattapoğlu, Mehmet Güneş, Mehmet Cemal Kaya, Faysal Ekici, Mehmet Guli Çetinçakmak, İbrahim Kaplan, Murad Atmac. The relationship between oxidative stress markers and 1H-Magnetic resonance spectroscopy findings in Obsessive compulsive disorder. Brain research. 2024-03-17. PMID:38494099. |
the purpose of this study was to examine n-acetyl aspartate (naa)/creatine (cr) and glutamate, glutamine, and gamma-aminobutyric acid complex (glx)/cr levels in patients with obsessive compulsive disorder (ocd) and healthy controls' orbitofrontal cortex (ofc) and caudate nucleus (cn) by proton magnetic resonance spectroscopy (1h-mrs) method and to investigate their relationship with oxidative stress markers glutathione peroxidase (gpx) and superoxide dismutase (sod). |
2024-03-17 |
2024-03-20 |
Not clear |
| Robert Cole Boggs, Lora Talley Watts, Peter T Fox, Geoffrey D Clark. Metabolic Diaschisis in Mild Traumatic Brain Injury. Journal of neurotrauma. 2024-03-14. PMID:38482809. |
metabolites measured by mrs included n-acetyl aspartate (naa), aspartate (asp), lactate (lac), glutathione (gsh), and glutamate (glu). |
2024-03-14 |
2024-03-16 |
rat |
| H Marahrens, K von Dörnberg, V Molnár, K M Gregor, E Leitzen, A von Altrock, A Polifka, M Ganter, M G Wagene. Copper Intoxication in South American Camelids-Review of the Literature and First Report of a Case in a Vicuña (Vicugna vicugna). Biological trace element research. 2024-02-29. PMID:38421580. |
laboratory findings from edta and serum samples revealed neutrophilia with a left shift, hypoproteinaemia, lymphopaenia, azotaemia, elevated levels of creatine kinase (ck), aspartate aminotransferase (ast) and glutamate dehydrogenase (gldh) in the serum. |
2024-02-29 |
2024-03-02 |
Not clear |
| Ye Wang, Chunxiao Cheng, Yanjun Lu, Zhaowu Lian, Qi Liu, Yanchao Xu, Yunzheng Li, Huan Li, Laizhu Zhang, Xiang Jiang, Binghua Li, Decai Y. β-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma. Cancer research. 2024-02-28. PMID:38417136. |
β-catenin/lef1 activated the transcription of the glutamate dehydrogenase glud1, which then promoted ammonia utilization to enhance the production of glutamate, aspartate, and proline as evidenced by 15nh4cl metabolic flux. |
2024-02-28 |
2024-03-02 |
Not clear |
| Lauren Revie, Claudia Metzler-Baddele. Age-related fornix decline predicts conservative response strategy-based slowing in perceptual decision-making. Aging brain. vol 5. 2024-02-06. PMID:38318456. |
estimates of metabolite concentrations [n-acetyl aspartate (naa), glutamate (glx), and γ-aminobutyric acid (gaba), creatine (cr), choline (cho), myoinositol (mi)] were measured from occipital (occ), anterior cingulate (acc) and posterior parietal cortices (ppc). |
2024-02-06 |
2024-02-09 |
Not clear |
| Zheqiong Tan, Keerti Boyapati, Caitlin M Tressler, Nicole Jenkinson, Kristine Glund. Glutamine transporter SLC38A3 promotes breast cancer metastasis via Gsk3β/β-catenin/EMT pathway. Cancer letters. 2024-02-03. PMID:38309615. |
our study reveals that slc38a3 regulates cellular glutamine, glutamate, asparagine, aspartate, alanine, and glutathione (gsh) levels in breast cancer cells. |
2024-02-03 |
2024-02-06 |
Not clear |
| Teresa Tsai, Sabrina Reinehr, Leonie Deppe, Alexandra Strubbe, Nils Kluge, H Burkhard Dick, Stephanie C Joachi. Glaucoma Animal Models beyond Chronic IOP Increase. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255979. |
we introduce genetically modified mice, e.g., the optineurin e50k knock-in or the glutamate aspartate transporter (glast)-deficient mouse. |
2024-01-23 |
2024-01-25 |
mouse |