| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert A Wyttenbach, Bruce R Johnso. Recording from Snail Motor Nerves to Investigate Central Pattern Generation. Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience. vol 20. issue 3. 2024-07-22. PMID:39036715. |
in a standard three-hour class period, students do a dissection, record from several nerves, and perform experimental manipulations such as adding feeding stimulants, serotonin, or dopamine to the preparation. |
2024-07-22 |
2024-07-24 |
Not clear |
| Mengjie Su, Wenjing Peng, Zhengyuan Ding, Yaqiu Zhou, Hui Gao, Qiyu Jiang, Chunmei Y. Multi-walled carbon nanotubes-metal-organic framework nanocomposite based sensor for the monitoring of multiple monoamine neurotransmitters in living cells. Bioelectrochemistry (Amsterdam, Netherlands). vol 160. 2024-07-17. PMID:39018612. |
the levels of monoamine neurotransmitters (mnts) including dopamine (da), adrenaline (adr), norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in cells are useful indicators to explore the pathogenesis of mnts-related diseases such as alzheimer's disease, parkinson's disease and depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. |
monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). |
2024-07-13 |
2024-07-16 |
rat |
| Susanne Nikolaus, Benedetta Fazari, Owen Y Chao, Filipe Rodrigues Almeida, Laila Abdel-Hafiz, Markus Beu, Jan Henke, Christina Antke, Hubertus Hautzel, Eduards Mamlins, Hans-Wilhelm Müller, Joseph P Huston, Charlotte von Gall, Frederik L Giese. 2,5-Dimethoxy-4-iodoamphetamine and altanserin induce region-specific shifts in dopamine and serotonin metabolization pathways in the rat brain. Pharmacology, biochemistry, and behavior. 2024-07-13. PMID:39002804. |
for understanding the neurochemical mechanism of neuropsychiatric conditions associated with cognitive deficits it is of major relevance to elucidate the influence of serotonin (5-ht) agonists and antagonists on memory function as well dopamine (da) and 5-ht release and metabolism. |
2024-07-13 |
2024-07-16 |
rat |
| Efthalia Angelopoulou, Anastasia Bougea, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis G Papageorgio. Unraveling the Potential Underlying Mechanisms of Mild Behavioral Impairment: Focusing on Amyloid and Tau Pathology. Cells. vol 13. issue 13. 2024-07-12. PMID:38995015. |
dysregulation of the hypothalamic-pituitary-adrenal (hpa) axis, disruption of neurotrophic factors, such as the brain-derived neurotrophic factor (bdnf), abnormal neuroinflammatory responses including the kynurenine pathway, dysregulation of transforming growth factor beta (tgf-β1), epigenetic alterations including micro-rna (mir)-451a and mir-455-3p, synaptic dysfunction, imbalance in neurotransmitters including acetylcholine, dopamine, serotonin, gamma-aminobutyric acid (gaba) and norepinephrine, as well as altered locus coeruleus (lc) integrity are some of the potential mechanisms connecting mbi with amyloid and tau pathology. |
2024-07-12 |
2024-07-14 |
Not clear |
| Arnav Paul, Diwakar Shukl. Oligomerization of Monoamine Transporters. Sub-cellular biochemistry. vol 104. 2024-07-04. PMID:38963486. |
the mat family functions using the electrochemical gradient of ions across the membrane and comprises three transporters, dopamine transporter (dat), serotonin transporter (sert), and norepinephrine transporter (net). |
2024-07-04 |
2024-07-10 |
Not clear |
| Basiru Olaitan Ajiboye, Toluwase Hezekiah Fatoki, Olamilekan Ganiu Akinola, Kazeem Olasunkanmi Ajeigbe, Abraham Fisayo Bamisaye, Eva-María Domínguez-Martín, Patricia Rijo, Babatunji Emmanuel Oyinloy. In silico exploration of anti-prostate cancer compounds from differential expressed genes. BMC urology. vol 24. issue 1. 2024-07-03. PMID:38956591. |
the findings revealed a total of 79 upregulated degs and 110 downregulated degs in pca, which were used to identify drug compounds capable of reversing the dysregulated conditions (dexverapamil, emetine, parthenolide, dobutamine, terfenadine, pimozide, mefloquine, ellipticine, and trifluoperazine) at a threshold probability of 20% on several molecular targets, such as serotonin receptors 2a/2b/2c, herg protein, adrenergic receptors alpha-1a/2a, dopamine d3 receptor, inducible nitric oxide synthase (inos), epidermal growth factor receptor erbb1 (egfr), tyrosine-protein kinases, and c-c chemokine receptor type 5 (ccr5). |
2024-07-03 |
2024-07-06 |
Not clear |
| Pallavi Singh, Priyanka Agrawal, K P Sing. Prenatal exposure to vortioxetine and vilazodone: Impact on depressive- and anxiety-like behavioral manifestations in young rat offspring. Behavioural brain research. 2024-06-30. PMID:38945303. |
additionally, neurotransmitter (serotonin, dopamine, and nor-epinephrine) levels in the prefrontal cortex region of the brain were substantially reduced in exposed offspring. |
2024-06-30 |
2024-07-03 |
rat |
| Benneth Ben-Azu, Benjamin Oritsemuelebi, Akpobo M Oghorodi, Adaeze Adebesin, Happy Isibor, Anthony T Eduviere, Oghenemine S Otuacha, Moses Akudo, Surhirime Ekereya, Isioma F Maidoh, Joy O Iyayi, Faith C Uzochukwu-Godfre. Psychopharmacological interaction of alcohol and posttraumatic stress disorder: effective action of naringin. European journal of pharmacology. 2024-06-29. PMID:38944175. |
our assays on the hpa-axis showed exacerbated increased corticosterone release and adrenal hypertrophy, accompanied by marked dopamine and serotonin increase, with depleted glutamic acid decarboxylase enzyme in the three brain regions, which naringin, however, reversed, respectively. |
2024-06-29 |
2024-07-02 |
mouse |
| Antonino Messina, Fabrizio Bella, Giuliana Maccarone, Alessandro Rodolico, Maria Salvina Signorell. Neutrophil-Lymphocyte Ratio Values in Schizophrenia: A Comparison between Oral and Long-Acting Antipsychotic Therapies. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928602. |
antipsychotic medications are used to treat this condition by inhibiting d2 dopamine and 5ht2 serotonin receptors. |
2024-06-27 |
2024-06-29 |
Not clear |
| Neha S Rawani, Allen W Chan, Serdar M Dursun, Glen B Bake. The Underlying Neurobiological Mechanisms of Psychosis: Focus on Neurotransmission Dysregulation, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction. Antioxidants (Basel, Switzerland). vol 13. issue 6. 2024-06-27. PMID:38929148. |
in the current review, it is reported how several of these factors, namely dysregulation of neurotransmitters [dopamine, serotonin, glutamate, and γ-aminobutyric acid (gaba)], neuroinflammation, glia (microglia, astrocytes, and oligodendrocytes), the hypothalamic-pituitary-adrenal axis, the gut microbiome, oxidative stress, and mitochondrial dysfunction contribute to psychosis and interact with one another. |
2024-06-27 |
2024-06-29 |
Not clear |
| Nian-Sheng Tzeng, Jing-Yi Chung, Chen-Cheng Lin, Pao-Yun Cheng, Yia-Ping Li. Effects of Subchronic Buspirone Treatment on Depressive Profile in Socially Isolated Rats: Implication of Early Life Experience on 5-HT1A Receptor-Related Depression. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931384. |
efflux levels of 5-ht, dopamine (da), and norepinephrine (ne) were detected in the hippocampus by brain dialysis. |
2024-06-27 |
2024-06-29 |
rat |
| Emily T O'Gorman, Gregory J Meye. Developmental cascades from early childhood attachment security to adolescent level of personality functioning among high-risk youth. Development and psychopathology. 2024-06-27. PMID:38934483. |
data from 2,268 children (1165 male; 1103 female) and caregivers participating in future of families and child well-being study (ffcws) were used to examine (1) effects of genetic polymorphisms of the serotonin transporter (5-httlpr) and dopamine d4 receptor (drd4) genes and adverse childhood experiences (aces) on attachment security and emotional and behavioral dysregulation in early childhood and (2) longitudinal associations and transactional relationships among attachment security, dysregulation, negative parenting attitudes and behaviors, social competence, and adolescent personality functioning. |
2024-06-27 |
2024-06-29 |
Not clear |
| Menglu Yuan, Frances M Lesli. Nicotine and fluoxetine alter adolescent dopamine-mediated behaviors via 5-HT Frontiers in psychiatry. vol 15. 2024-06-26. PMID:38919632. |
nicotine and fluoxetine alter adolescent dopamine-mediated behaviors via 5-ht abuse or misuse of tobacco, e-cigarettes, or antidepressants may have serious clinical consequences during adolescence, a sensitive period during brain development when the distinct neurobiology of adolescent serotonin (5-ht) and dopamine (da) systems create unique behavioral vulnerabilities to drugs of abuse. |
2024-06-26 |
2024-06-29 |
Not clear |
| Guilherme Fusetto Veronesi, Alessandra Gabellone, Anneka Tomlinson, Marco Solmi, Christoph U Correll, Samuele Cortes. Treatments in the pipeline for attention-deficit/hyperactivity disorder (ADHD) in adults. Neuroscience and biobehavioral reviews. 2024-06-24. PMID:38914177. |
while several pharmacological and non-pharmacological interventions had evidence of superiority compared to the control condition from a single rct, centanafadine (norepinephrine, dopamine, and serotonin re-uptake inhibitor) was the only treatment with evidence of efficacy on adhd core symptoms (small effect size=0.28-0.40) replicated in at least one additional rct, alongside reasonable tolerability. |
2024-06-24 |
2024-06-27 |
Not clear |
| Nadiah Alyamni, Jandro L Abot, Alexander G Zesto. Voltammetric detection of Neuropeptide Y using a modified sawhorse waveform. Analytical and bioanalytical chemistry. 2024-06-24. PMID:38914733. |
use of msw improves npy detection sensitivity and selectivity by reducing interference from catecholamines like dopamine, serotonin, and others compared to the traditional triangle waveform. |
2024-06-24 |
2024-06-27 |
Not clear |
| Lining Yin, Ying Yu, Fang Han, Qingyun Wan. Unveiling serotonergic dysfunction of obsessive-compulsive disorder on prefrontal network dynamics: a computational perspective. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-21. PMID:38904079. |
here, we incorporate 5-ht receptors (5-ht1a, 5-ht2a) and dopamine receptors into a multistable prefrontal cortex network model, replicating the experimentally observed inverted u-curve phenomenon. |
2024-06-21 |
2024-06-23 |
Not clear |
| Lining Yin, Ying Yu, Fang Han, Qingyun Wan. Unveiling serotonergic dysfunction of obsessive-compulsive disorder on prefrontal network dynamics: a computational perspective. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-21. PMID:38904079. |
this suggests a hypothesis wherein elevated dopamine concentrations in obsessive-compulsive disorder might result from primary deficits in serotonin levels. |
2024-06-21 |
2024-06-23 |
Not clear |
| Geeta Ilipilla, L Eugene Arnol. The role of adrenergic neurotransmitter reuptake inhibitors in the ADHD armamentarium. Expert opinion on pharmacotherapy. 2024-06-20. PMID:38900676. |
due to their effects on norepinephrine, dopamine, and serotonin neurotransmission, they benefit both adhd and comorbid disorders and have some other advantages including longer duration of action and fewer adverse effects compared to stimulants. |
2024-06-20 |
2024-06-23 |
Not clear |
| Walaa G Abdelhamid, Noha A Mowaad, Gihan F Asaad, Asmaa F Galal, Sarah S Mohammed, Olfat E Mostafa, Doaa R Sadek, Lobna A Elkhate. The potential protective effect of Camellia Sinensis in mitigating monosodium glutamate-induced neurotoxicity: biochemical and histological study in male albino rats. Metabolic brain disease. 2024-06-13. PMID:38869783. |
msg administration resulted in significant neurotoxicity in rats that was revealed by the significant reduction of serum concentration of glutathione peroxidase (gpx) and nitric oxide (no), and the significant elevation of total antioxidant capacity (tac) accompanied by the significant reduction of levels of serum monoamines (dopamine, serotonin, and norepinephrine) and histological changes in the hippocampus area ca1, dentate gyrus, and cerebellar cortex and positive immunohistochemical staining of glial fibrillary acidic proteins (gfap) and calretinin. |
2024-06-13 |
2024-06-15 |
rat |