| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. |
monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). |
2024-07-13 |
2024-07-16 |
rat |
| Parya Alizadeh Khosroshahi, Mohammad Ghanbar. MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches. Progress in neuro-psychopharmacology & biological psychiatry. 2024-07-13. PMID:39002925. |
microrna dysregulation in glutamate and dopamine pathways of schizophrenia: from molecular pathways to diagnostic and therapeutic approaches. |
2024-07-13 |
2024-07-16 |
Not clear |
| Parya Alizadeh Khosroshahi, Mohammad Ghanbar. MicroRNA dysregulation in glutamate and dopamine pathways of schizophrenia: From molecular pathways to diagnostic and therapeutic approaches. Progress in neuro-psychopharmacology & biological psychiatry. 2024-07-13. PMID:39002925. |
as epigenetic factors, mirnas regulate many genes involved in glutamate and dopamine signaling pathways; thereby, their dysregulation can contribute to the development of schizophrenia. |
2024-07-13 |
2024-07-16 |
Not clear |
| Neha S Rawani, Allen W Chan, Serdar M Dursun, Glen B Bake. The Underlying Neurobiological Mechanisms of Psychosis: Focus on Neurotransmission Dysregulation, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction. Antioxidants (Basel, Switzerland). vol 13. issue 6. 2024-06-27. PMID:38929148. |
in the current review, it is reported how several of these factors, namely dysregulation of neurotransmitters [dopamine, serotonin, glutamate, and γ-aminobutyric acid (gaba)], neuroinflammation, glia (microglia, astrocytes, and oligodendrocytes), the hypothalamic-pituitary-adrenal axis, the gut microbiome, oxidative stress, and mitochondrial dysfunction contribute to psychosis and interact with one another. |
2024-06-27 |
2024-06-29 |
Not clear |
| M Flavia Barbano, Jia Qi, Emma Chen, Uzma Mohammad, Orlando Espinoza, Marcos Candido, Huiling Wang, Bing Liu, Suyun Hahn, François Vautier, Marisela Morale. VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-26. PMID:38926603. |
converging evidence indicates that both dopamine and glutamate neurotransmission within the nucleus accumbens (nac) play a role in psychostimulant self-administration and relapse in rodent models. |
2024-06-26 |
2024-06-29 |
mouse |
| M Flavia Barbano, Jia Qi, Emma Chen, Uzma Mohammad, Orlando Espinoza, Marcos Candido, Huiling Wang, Bing Liu, Suyun Hahn, François Vautier, Marisela Morale. VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-26. PMID:38926603. |
increased nac dopamine release from ventral tegmental area (vta) inputs is critical to psychostimulant self-administration and nac glutamate release from prelimbic prefrontal cortex (pfc) inputs synapsing on medium spiny neurons (msns) is critical to reinstatement of psychostimulant-seeking after extinction. |
2024-06-26 |
2024-06-29 |
mouse |
| M Flavia Barbano, Jia Qi, Emma Chen, Uzma Mohammad, Orlando Espinoza, Marcos Candido, Huiling Wang, Bing Liu, Suyun Hahn, François Vautier, Marisela Morale. VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-06-26. PMID:38926603. |
the regulation of the activity of msns by vta dopamine inputs has been extensively studied, and recent findings have demonstrated that vta glutamate neurons target the nac medial shell. |
2024-06-26 |
2024-06-29 |
mouse |
| Dillon J McGovern, Alysabeth Phillips, Annie Ly, Emily D Prévost, Lucy Ward, Kayla Siletti, Yoon Seok Kim, Lief E Fenno, Charu Ramakrishnan, Karl Deisseroth, Christopher P Ford, David H Roo. Salience signaling and stimulus scaling of ventral tegmental area glutamate neuron subtypes. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915564. |
subsets of vta vglut2+ neurons are capable of co-transmitting glutamate and gaba (vglut2+vgat+ neurons), transmitting glutamate without gaba (vglut2+vgat- neurons), or co-transmitting glutamate and dopamine (vglut2+th+ neurons), but whether these molecularly distinct subpopulations show behavior-related differences is not wholly understood. |
2024-06-25 |
2024-06-27 |
Not clear |
| Rhiana C Simon, Mary C Loveless, Joshua X Yee, Brandon Goh, Su G Cho, Zainab Nasir, Koichi Hashikawa, Garret D Stuber, Larry S Zweifel, Marta E Sode. Opto-seq reveals input-specific immediate-early gene induction in ventral tegmental area cell types. Neuron. 2024-06-20. PMID:38901431. |
the ventral tegmental area (vta) is a critical node in circuits governing motivated behavior and is home to diverse populations of neurons that release dopamine, gamma-aminobutyric acid (gaba), glutamate, or combinations of these neurotransmitters. |
2024-06-20 |
2024-06-23 |
Not clear |
| Lucie Oriol, Melody Chao, Grace J Kollman, Dina S Dowlat, Sarthak M Singhal, Thomas Steinkellner, Thomas S Hnask. Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895464. |
the ventral tegmental area (vta) contains projection neurons that release the neurotransmitters dopamine, gaba, and/or glutamate from distal synapses. |
2024-06-19 |
2024-06-21 |
Not clear |
| Abhinav Singh, Maryam Sarwat, Sangeetha Gupt. Pharmacological Mechanism of Herbal Interventions for Bipolar Disorder. Current pharmaceutical design. 2024-06-07. PMID:38847247. |
alterations in the circuits, including the prefrontal cortex, striatum, and limbic system, regulate mood and cause variation in several crucial neurotransmitters, including serotonin, dopamine, gaba, and glutamate. |
2024-06-07 |
2024-06-10 |
Not clear |
| Gao-Lin Qiu, Li-Jun Peng, Peng Wang, Zhi-Lai Yang, Ji-Qian Zhang, Hu Liu, Xiao-Na Zhu, Jin Rao, Xue-Sheng Li. Zoological research. vol 45. issue 3. 2024-05-20. PMID:38766749. |
here, we measured the dynamics of five neurotransmitters, including γ-aminobutyric acid, glutamate, norepinephrine, acetylcholine, and dopamine, in the medial prefrontal cortex and primary visual cortex of c57bl/6 mice through |
2024-05-20 |
2024-05-27 |
mouse |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Vivien Zell, Cody Sargent, Andrew Flores, Nick G Hollon, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. Nature communications. vol 15. issue 1. 2024-05-18. PMID:38762463. |
stimulation of vp gaba neurons inhibited vta gaba, but activated dopamine and glutamate neurons. |
2024-05-18 |
2024-05-27 |
human |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Vivien Zell, Cody Sargent, Andrew Flores, Nick G Hollon, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. Nature communications. vol 15. issue 1. 2024-05-18. PMID:38762463. |
conversely, vp glutamate neurons activated vta gaba, as well as dopamine and glutamate neurons, despite driving aversion. |
2024-05-18 |
2024-05-27 |
human |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Vivien Zell, Cody Sargent, Andrew Flores, Nick G Hollon, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. Nature communications. vol 15. issue 1. 2024-05-18. PMID:38762463. |
however, vp glutamate neurons evoked dopamine in aversion-associated ventromedial nucleus accumbens (nac), but reduced dopamine release in reward-associated dorsomedial nac. |
2024-05-18 |
2024-05-27 |
human |
| Xiaoying Tan, Elizabeth M Neslund, Khawla Fentis, Zheng-Ming Din. Fluorocitrate inhibition of astrocytes reduces nicotine self-administration and alters extracellular levels of glutamate and dopamine within the nucleus accumbens in male Wistar rats. Neuropharmacology. 2024-05-16. PMID:38750804. |
fluorocitrate inhibition of astrocytes reduces nicotine self-administration and alters extracellular levels of glutamate and dopamine within the nucleus accumbens in male wistar rats. |
2024-05-16 |
2024-05-27 |
rat |
| Xiaoying Tan, Elizabeth M Neslund, Khawla Fentis, Zheng-Ming Din. Fluorocitrate inhibition of astrocytes reduces nicotine self-administration and alters extracellular levels of glutamate and dopamine within the nucleus accumbens in male Wistar rats. Neuropharmacology. 2024-05-16. PMID:38750804. |
these results indicate that nicotine reinforcement upregulates the astrocyte marker gfap expression in the naccr, metabolic inhibition of astrocytes attenuates nicotine reinforcement and relapse, and metabolic inhibition of astrocytes disrupts extracellular dopamine and glutamate transmission. |
2024-05-16 |
2024-05-27 |
rat |
| Xiaoying Tan, Elizabeth M Neslund, Khawla Fentis, Zheng-Ming Din. Fluorocitrate inhibition of astrocytes reduces nicotine self-administration and alters extracellular levels of glutamate and dopamine within the nucleus accumbens in male Wistar rats. Neuropharmacology. 2024-05-16. PMID:38750804. |
overall, these findings suggest that astrocytes play an important role in nicotine reinforcement and relapse, potentially through regulation of extracellular glutamate and dopamine neurotransmission. |
2024-05-16 |
2024-05-27 |
rat |
| Shashi B Singh, Atit Tiwari, Maanya R Katta, Riju Kafle, Cyrus Ayubcha, Krishna H Patel, Yash Bhattarai, Thomas J Werner, Abass Alavi, Mona-Elisabeth Revhei. The utility of PET imaging in depression. Frontiers in psychiatry. vol 15. 2024-05-08. PMID:38711875. |
studies have revealed alterations in neurotransmitter systems such as serotonin, dopamine, gaba, and glutamate, which are linked to the pathophysiology of depression. |
2024-05-08 |
2024-05-27 |
Not clear |
| Sixtine Fleury, Rhonda Kolaric, Justin Espera, Quan Ha, Jacquelyn Tomaio, Ulrik Gether, Andreas Toft Sørensen, Susana Mingot. Role of dopamine neurons in familiarity. The European journal of neuroscience. 2024-04-23. PMID:38650479. |
dopamine neurons that show responsiveness to novelty were primarily located in the paranigral nucleus of the vta and expressed vesicular glutamate transporter 2 transcripts, marking them as dopamine-glutamate neurons. |
2024-04-23 |
2024-04-26 |
mouse |