All Relations between suprapyramidal blade and molecular layer

Publication Sentence Publish Date Extraction Date Species
Ankangzhi Ma, Yawei Mu, Zixuan Wei, Menghan Sun, Junjie Li, Hanyang Jiang, Cuiqing Zhu, Xianhua Che. SRSF10 regulates migration of neural progenitor cells and granule cells and affects the formation of dentate gyrus during the development of mouse hippocampus. Neuroscience. 2024-07-03. PMID:38960088. in this study, using srsf10 conditional knock-out mice in neural progenitor cells (npcs), we found that dysfunction of srsf10 leads to developmental defects in the dentate gyrus of hippocampus, which manifests as the reduced length and wider suprapyramidal blade and infrapyramidal blade.furthermore, we proved that loss of srsf10 in npcs caused inhibition of the differentiation activity and the abnormal migration of npcs and granule cells, resulting in reduced granule cells and more ectopic granule cells dispersed in the molecular layer and hilus. 2024-07-03 2024-07-10 mouse