| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Elfoul. Improved Mathematical Models of Parkinson's Disease with Hopf Bifurcation and Huntington's Disease with Chaos. Acta biotheoretica. vol 72. issue 3. 2024-09-02. PMID:39223402. |
a decrease of gaba in the striatum or delayed excitation of the substantia nigra from the subthalamus may be a major cause of parkinson's disease. |
2024-09-02 |
2024-09-05 |
Not clear |
| Luana Gilio, Diego Fresegna, Mario Stampanoni Bassi, Alessandra Musella, Francesca De Vito, Sara Balletta, Krizia Sanna, Silvia Caioli, Luigi Pavone, Giovanni Galifi, Ilaria Simonelli, Livia Guadalupi, Valentina Vanni, Fabio Buttari, Ettore Dolcetti, Antonio Bruno, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Annamaria Finardi, Roberto Furlan, Diego Centonze, Georgia Mandoles. Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-08-22. PMID:39169949. |
notably, il-10 exhibited the ability to decrease glutamate transmission, increase gaba transmission in the striatum, and reverse il-1β-induced abnormal synaptic transmission in eae. |
2024-08-22 |
2024-08-24 |
mouse |
| Triana Acevedo-Huergo, Jonathan Sánchez-Yépez, María Soledad Mendoza-Trejo, Isela Hernández-Plata, Magda Giordano, Verónica Mireya Rodrígue. Hypoactivity and neurochemical alterations in the basal ganglia of female Sprague-Dawley rats after repeated exposure to atrazine. Frontiers in toxicology. vol 6. 2024-08-20. PMID:39161789. |
our study aimed to assess the effects of repeated ip injections of 100 mg atr/kg or a vehicle every other day for 2 weeks (six injections) on the locomotor activity, content of monoamines, gaba, glutamate, and glutamine in the striatum, nucleus accumbens, ventral midbrain, and prefrontal cortex, and tyrosine hydroxylase (th) protein levels in striatum and nucleus accumbens of female rats. |
2024-08-20 |
2024-08-22 |
rat |
| Abhinav Singh, Maryam Sarwat, Sangeetha Gupt. Pharmacological Mechanism of Herbal Interventions for Bipolar Disorder. Current pharmaceutical design. 2024-06-07. PMID:38847247. |
alterations in the circuits, including the prefrontal cortex, striatum, and limbic system, regulate mood and cause variation in several crucial neurotransmitters, including serotonin, dopamine, gaba, and glutamate. |
2024-06-07 |
2024-06-10 |
Not clear |
| Cesar C Ceballos, Lei Ma, Maozhen Qin, Haining Zhon. Prevalent co-release of glutamate and GABA throughout the mouse brain. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585864. |
although dopaminergic axons release both glutamate and gaba in the striatum, deletion of dopamine neurons did not eliminate biphasic minis, indicating that the co-release originates from another neuronal type. |
2024-04-08 |
2024-04-10 |
mouse |
| Ann-Kathrin Stock, Annett Werner, Paul Kuntke, Miriam-Sophie Petasch, Wiebke Bensmann, Nicolas Zink, Anna Helin Koyun, Boris B Quednow, Christian Best. Gamma-Aminobutyric Acid and Glutamate Concentrations in the Striatum and Anterior Cingulate Cortex Not Found to Be Associated with Cognitive Flexibility. Brain sciences. vol 13. issue 8. 2023-08-26. PMID:37626548. |
gamma-aminobutyric acid and glutamate concentrations in the striatum and anterior cingulate cortex not found to be associated with cognitive flexibility. |
2023-08-26 |
2023-09-07 |
Not clear |
| Charles Ducrot, Gregory de Carvalho, Benoit Delignat-Lavaud, Constantin V L Delmas, Priyabrata Halder, Nicolas Giguère, Consiglia Pacelli, Sriparna Mukherjee, Marie-Josée Bourque, Martin Parent, LuLu Y Chen, Louis-Eric Trudea. Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons. eLife. vol 12. 2023-07-06. PMID:37409563. |
strikingly, electrophysiological recordings revealed an increase of gaba co-release from da neuron axons in the striatum of these mice. |
2023-07-06 |
2023-08-14 |
mouse |
| Josua Zimmermann, Niklaus Zölch, Rebecca Coray, Francesco Bavato, Nicole Friedli, Markus R Baumgartner, Andrea E Steuer, Antje Opitz, Annett Werner, Georg Oeltzschner, Erich Seifritz, Ann Kathrin Stock, Christian Beste, David M Cole, Boris B Quedno. Chronic 3,4-Methylenedioxymethamphetamine (MDMA) use is related to glutamate and GABA concentrations in the striatum, but not in the anterior cingulate cortex. The international journal of neuropsychopharmacology. 2023-05-26. PMID:37235749. |
chronic 3,4-methylenedioxymethamphetamine (mdma) use is related to glutamate and gaba concentrations in the striatum, but not in the anterior cingulate cortex. |
2023-05-26 |
2023-08-14 |
rat |
| Nao Chuhma, Soo Jung Oh, Stephen Raypor. The dopamine neuron synaptic map in the striatum. Cell reports. vol 42. issue 3. 2023-03-03. PMID:36867530. |
dopamine neurons project to the striatum to control movement, cognition, and motivation via slower volume transmission as well as faster dopamine, glutamate, and gaba synaptic actions capable of conveying the temporal information in dopamine neuron firing. |
2023-03-03 |
2023-08-14 |
Not clear |
| Aeseul Kim, Sun Mi Gu, Haemiru Lee, Dong Eun Kim, Jin Tae Hong, Jaesuk Yun, Hye Jin Ch. Prenatal ketamine exposure impairs prepulse inhibition via arginine vasopressin receptor 1A-mediated GABAergic neuronal dysfunction in the striatum. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 160. 2023-02-04. PMID:36738499. |
in the striatum of offspring, ketamine or methoxetamine treatment increased glutamate decarboxylase 67 (gad67) and δ-aminobutyric acid (gaba) levels. |
2023-02-04 |
2023-08-14 |
rat |
| Yu Guo, Huan Zhu, Yuanyuan Wang, Tingting Sun, Jiajia Xu, Tie Wang, Weijun Guan, Chunjing Wang, Changqing Liu, Caiyun M. Miniature-swine iPSC-derived GABA progenitor cells function in a rat Parkinson's disease model. Cell and tissue research. 2023-01-16. PMID:36645476. |
moreover, over 50% of the grafted mipsc-igabaps could express gaba, and these gabaergic neurons might be responsible for modifying the balance of excitatory and inhibitory signals in the striatum to promote behavioral recovery. |
2023-01-16 |
2023-08-14 |
rat |
| Ying Xing, Anjing Zhang, Congqin Li, Jing Han, Jun Wang, Lu Luo, Xuechun Chang, Zhanzhuang Tian, Yulong Ba. Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice. Molecular neurobiology. 2022-12-29. PMID:36580196. |
overall, those results reveal that the dorsal striatum-projecting subpopulation of cortical glutamatergic neurons can influence gaba levels in the striatum, playing a critical role in modulating exercise-induced improvement of motor and anxiety-like behavior. |
2022-12-29 |
2023-08-14 |
mouse |
| Xiaoli Ji, Yingying Zhou, Qinqin Gao, Hui He, Ziyan Wu, Ban Feng, Yuting Mei, Yan Cheng, Wenhao Zhou, Yuejun Chen, Man Xion. Functional reconstruction of the basal ganglia neural circuit by human striatal neurons in hypoxic-ischaemic injured brain. Brain : a journal of neurology. 2022-12-14. PMID:36516880. |
here, by administrating genetically labelled human embryonic stem cell-derived striatal neural progenitors into the ipsilateral striatum of hypoxic-ischaemic encephalopathy-injured mice, we found that the grafted cells gradually matured into gaba spiny projection neurons morphologically and electrophysiologically, and significantly rescued the area loss of hypoxic-ischaemic encephalopathy-injured brains. |
2022-12-14 |
2023-08-14 |
mouse |
| Susen Becker, Anja Schulz, Sophia Kreyer, Jan Dreßler, Angelika Richter, Christin Helmschrod. Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry. Talanta. vol 253. 2022-10-08. PMID:36208557. |
basal extracellular concentrations of the following analytes: 5-ht, 5-hiaa, me, da, 3-mt, hva, ach, iso-ach, ch, gaba, ade, gln, and glu were determined in the striatum of mice with a md flow rate of 0.5 μl/min. |
2022-10-08 |
2023-08-14 |
mouse |
| D Y Reyes-Bravo, P Villalobos-Aguilera, J T Almonte-Zepeda, M S Mendoza-Trejo, M Giordano, A Orozco, V M Rodrígue. Chronic atrazine exposure increases the expression of genes associated with GABAergic and glutamatergic systems in the brain of male albino rat. Frontiers in toxicology. vol 4. 2022-09-08. PMID:36071823. |
at the end of the atr treatment, the levels of mrna of several genes involved in the production, vesiculation, reuptake, and receptors of gaba and glu in the striatum (str), nucleus accumbens (nacc), prefrontal cortex (pfc), ventral midbrain (vmid) and hippocampus (hipp) were evaluated by absolute qpcr. |
2022-09-08 |
2023-08-14 |
rat |
| Hitomi Shikano, Akari Ikeda, Yuko Maejima, Shoko Kobayashi, Tsutomu Terauchi, Jun Yokoyama, Kenju Shimomura, Shu Tair. Optimization of the use of Py-Tag for next generation derivatization reagents in imaging mass spectrometry. Journal of bioscience and bioengineering. 2022-07-05. PMID:35781190. |
brain sections of unilateral 6-ohda lesioned parkinson's disease model rats showed py-tag da (m/z 328.3) in the unilateral striatum and py-tag gaba (m/z 278.3) in the cerebral cortex, striatum, hippocampus and hypothalamus. |
2022-07-05 |
2023-08-14 |
rat |
| Edoardo Dalmato Schilke, Lucio Tremolizzo, Ildebrando Appollonio, Carlo Ferrares. Tics: neurological disorders determined by a deficit in sensorimotor gating processes. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-07-05. PMID:35781754. |
evidence points out that the limbic domain of the cstc loops, dopamine and gaba receptors within the striatum play an important role in ppi modulation. |
2022-07-05 |
2023-08-14 |
human |
| Asami Umino, Hisayuki Iwama, Masakazu Umino, Dai Shimazu, Yuji Kiuchi, Toru Nishikaw. Effects of Quinolinate-Induced Lesion of the Medial Prefrontal Cortex on Prefrontal and Striatal Concentrations of D-Serine in the Rat. Neurochemical research. 2022-05-23. PMID:35604516. |
a prominent reduction in the tissue levels of gaba in the interneurons of the prefrontal cortex (- 78%) without significant changes in those in the striatum (+ 12%) verified that a major lesion part was confined to the cortical portion. |
2022-05-23 |
2023-08-13 |
rat |
| Sarah M Zych, Christopher P For. Divergent properties and independent regulation of striatal dopamine and GABA co-transmission. Cell reports. vol 39. issue 7. 2022-05-18. PMID:35584679. |
both dopamine and gaba are loaded into snc synaptic vesicles by the vesicular monoamine transporter 2 (vmat2), and co-release of gaba provides strong inhibition to the striatum by directly inhibiting striatal medium spiny projection neurons (msns) through activation of gaba |
2022-05-18 |
2023-08-13 |
Not clear |
| Ana Paula Pesarico, José L Cechella, Cristina W Nogueira, Suzan G Ros. Swimming exercise and diphenyl diselenide-supplemented diet modulate cerebral cortical and striatal GABA uptake in aged rats. Anais da Academia Brasileira de Ciencias. vol 94. issue 1. 2022-01-12. PMID:35019002. |
after 4 weeks, the [3h]gaba uptake was determined in samples of cerebral cortex and striatum of rats. |
2022-01-12 |
2023-08-13 |
rat |