| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuxiao Tang, Yahui Ye, Kaichuang Yang, Xi Guo, Xin Gao, Cheng Wu, Jingyu Wang, Deqing Pen. Experimental study of cBMMSC based on nanosilver hydrogel nerve conduit for repairing spinal cord injury. Journal of cellular and molecular medicine. vol 28. issue 22. 2024-11-26. PMID:39588835. |
four weeks after transplantation, the expression of neuron-specific enolase (nse) in rat anti-human nuclear monoclonal antibody (mab1281)-positive cells was detected by immunostaining in spinal cord tissue sections of the two groups to assess the differentiation of cbmmsc to neuron-like cells in the nerve conduits after transplantation; the number of brdu-positive cells was detected to assess the neuronal regeneration of the localized spinal cord injury of the two groups; and the length of axons was observed with laser confocal photography was used to observe the length of axons; he staining was used to observe the scarring and cavities in the spinal cord sections of the two groups; immunofluorescence was used to detect neuron-like markers (nestin, nse, nf200, gfap) in the two groups, and the od values were determined by the image processing and analysis system (ipaas); and western blot was used to detect the neurotransmitters of motor fibres, acetylcholinesterase (chat), sensory fibres, and sensory fibres, as well as the neurotransmission of motor fibres, acetylcholine production-limiting enzyme (chat) and sensory fibre neurotransmitter glutamate synthase (gogat); motor function was assessed by bbb score; somatosensory evoked potentials (seps) and motor evoked potentials (meps) were detected by body surface electrode assay in the two groups, and the neurophysiological recovery effect was evaluated. |
2024-11-26 |
2024-11-28 |
rat |
| Fumie Shiba, Shiiko Maekawara, Atsuko Inoue, Koji Ohta, Mutsumi Miyauch. Antinociceptive effect of Equisetum arvense extract on the stomatitis hamster model. PloS one. vol 19. issue 11. 2024-11-21. PMID:39570913. |
the dorsal root ganglia of the rat spinal cord were isolated, dispersed, and cultured to examine the inhibitory effect of ea on the k+-evoked release of neurotransmitter substance p. in the stomatitis/100*ea group, a significant reduction in wound size was observed compared with the stomatitis/physiological saline (ps) group, and the weight gain rate was considerably higher. |
2024-11-21 |
2024-11-24 |
rat |
| Zhicheng Tian, Qi Zhang, Ling Wang, Mengxiang Li, Tianjing Li, Yujie Wang, Zixuan Cao, Xiaofan Jiang, Peng Lu. Progress in mechanism of pain associated with neurodegenerative diseases. Ageing research reviews. 2024-11-14. PMID:39542176. |
this article summarizes the underlying mechanisms of major ndds-associated pain: neuroinflammation, brain and spinal cord dysfunctions, mitochondrial dysfunction, risk gene and pathological protein, as well as receptor, channel, and neurotransmitter. |
2024-11-14 |
2024-11-17 |
Not clear |
| Hailong Yu, Weiwei Wan. Modulation of heteromeric glycine receptor function through high concentration clustering. bioRxiv : the preprint server for biology. 2024-10-28. PMID:39464082. |
human heteromeric glycine receptors (glyrs) are the major inhibitory neurotransmitter receptors in the spinal cord and are active targets for developing chronic pain medications. |
2024-10-28 |
2024-10-30 |
human |
| Caitlin Fenech, Bryony L Winters, Yo Otsu, Karin R Aubre. Supraspinal glycinergic neurotransmission in pain: A scoping review of current literature. Journal of neurochemistry. 2024-07-30. PMID:39075923. |
glycine's neurotransmitter roles have been most extensively investigated in the spinal cord, where it is known to play essential roles in pain, itch, and motor function. |
2024-07-30 |
2024-08-02 |
Not clear |
| Federico Fabris, Aram Megighian, Ornella Rossetto, Morena Simonato, Giampietro Schiavo, Marco Pirazzini, Cesare Montecucc. Local tetanus begins with a VAMP cleavage-associated neuromuscular junction paralysis around the site of tetanus neurotoxin release. The American journal of pathology. 2024-06-17. PMID:38885925. |
this paralysis follows the retrograde transport of tent inside the axons of spinal cord motoneurons and its uptake by inhibitory interneurons with cleavage of vamp, a synaptic vesicle protein required for neurotransmitter release. |
2024-06-17 |
2024-06-21 |
mouse |
| Michelle Trbovich, Yubo Wu, Terry Romo, Wouker Koek, Dean Kellog. Mechanistic involvement of noradrenergic neuronal neurotransmitter release in cutaneous vasoconstriction during autonomic dysreflexia in persons with spinal cord injury. Autonomic neuroscience : basic & clinical. vol 252. 2024-02-08. PMID:38330594. |
mechanistic involvement of noradrenergic neuronal neurotransmitter release in cutaneous vasoconstriction during autonomic dysreflexia in persons with spinal cord injury. |
2024-02-08 |
2024-02-11 |
Not clear |
| Yasmin Mirzaalikhan, Nasim Eslami, Amin Izadi, Faezeh Shekari, Sahar Kian. Spinal Cord Injury Affects Gene Expression of Transmembrane Proteins in Tissue and Release of Extracellular Vesicle in Blood: In Silico and Cell journal. vol 25. issue 11. 2023-12-10. PMID:38071409. |
spinal cord injury affects gene expression of transmembrane proteins in tissue and release of extracellular vesicle in blood: in silico and spinal cord injury (sci) can disrupt membrane transmission by affecting transmembrane channels or neurotransmitter release. |
2023-12-10 |
2023-12-17 |
rat |
| Xunjia Qian, Xinyi Zhao, Lulu Yu, Yujian Yin, Xiao-Dan Zhang, Liyun Wang, Jun-Xu Li, Qing Zhu, Jia-Lie Lu. Current status of GABA receptor subtypes in analgesia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 168. 2023-11-07. PMID:37935070. |
as the major inhibitory neurotransmitter, gaba plays pivotal roles in the regulation of pain sensation, which is initiated by the activation of peripheral nociceptors and transmitted to the spinal cord and brain along nerves. |
2023-11-07 |
2023-11-20 |
Not clear |
| Anna Starinets, Arina Ponomarenko, Anna Tyrtyshnaia, Igor Manzhul. Synaptamide modulates glial and neurotransmitter activity in the spinal cord during neuropathic pain. Journal of chemical neuroanatomy. 2023-11-07. PMID:37935251. |
synaptamide modulates glial and neurotransmitter activity in the spinal cord during neuropathic pain. |
2023-11-07 |
2023-11-20 |
rat |
| Siamak Salavatian, Elaine Marie Robbins, Yuki Kuwabara, Elisa Castagnola, Xinyan Tracy Cui, Aman Mahaja. Real-time in vivo thoracic spinal glutamate sensing reveals spinal hyperactivity during myocardial ischemia. bioRxiv : the preprint server for biology. 2023-03-30. PMID:36993301. |
the spinal cord neural network is crucial in triggering these arrhythmias and evaluating its neurotransmitter activity during ir is critical for understanding ventricular excitability control. |
2023-03-30 |
2023-08-14 |
Not clear |
| Emily Johnson, Marilyn Clark, Merve Oncul, Andreea Pantiru, Claudia MacLean, Jim Deuchars, Susan A Deuchars, Jamie Johnsto. Graded spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of the mouse spinal cord. iScience. vol 26. issue 1. 2023-01-24. PMID:36691620. |
graded spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of the mouse spinal cord. |
2023-01-24 |
2023-08-14 |
mouse |
| Qi-Yu Chen, Min Zhu. Glutamate acts as a key neurotransmitter for itch in the mammalian spinal cord. Molecular pain. 2023-01-06. PMID:36604775. |
glutamate acts as a key neurotransmitter for itch in the mammalian spinal cord. |
2023-01-06 |
2023-08-14 |
Not clear |
| Qi-Yu Chen, Min Zhu. Glutamate acts as a key neurotransmitter for itch in the mammalian spinal cord. Molecular pain. 2023-01-06. PMID:36604775. |
recent studies using genetic deletion techniques have proposed that gastrin-releasing peptide (grp) is a key neurotransmitter for itch in the spinal cord. |
2023-01-06 |
2023-08-14 |
Not clear |
| Barry D Waterhouse, Haven K Predale, Nicholas W Plummer, Patricia Jensen, Daniel J Chandle. Probing the structure and function of locus coeruleus projections to CNS motor centers. Frontiers in neural circuits. vol 16. 2022-10-17. PMID:36247730. |
the brainstem nucleus locus coeruleus (lc) sends projections to the forebrain, brainstem, cerebellum and spinal cord and is a source of the neurotransmitter norepinephrine (ne) in these areas. |
2022-10-17 |
2023-08-14 |
Not clear |
| Yulin Zhang, Jin Ke, Yuan Zhou, Xue Liu, Tianwen Huang, Feng Wan. Sex-specific characteristics of cells expressing the cannabinoid 1 receptor in the dorsal horn of the lumbar spinal cord. The Journal of comparative neurology. 2022-05-17. PMID:35580011. |
it has been shown that numerous neurotransmitter and neuromodulator systems in the spinal cord, including the endocannabinoid system and its main receptor, the cannabinoid 1 receptor (cb |
2022-05-17 |
2023-08-13 |
Not clear |
| Hannah Bertels, Guillem Vicente-Ortiz, Khadija El Kanbi, Aya Takeok. Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury. Nature neuroscience. vol 25. issue 5. 2022-05-06. PMID:35524138. |
neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury. |
2022-05-06 |
2023-08-13 |
mouse |
| Hannah Bertels, Guillem Vicente-Ortiz, Khadija El Kanbi, Aya Takeok. Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury. Nature neuroscience. vol 25. issue 5. 2022-05-06. PMID:35524138. |
in this study, we found that adult spinal cord injury prompts neurotransmitter switching of spatially defined excitatory interneurons to an inhibitory phenotype, promoting inhibition at synapses contacting motor neurons. |
2022-05-06 |
2023-08-13 |
mouse |
| Hannah Bertels, Guillem Vicente-Ortiz, Khadija El Kanbi, Aya Takeok. Neurotransmitter phenotype switching by spinal excitatory interneurons regulates locomotor recovery after spinal cord injury. Nature neuroscience. vol 25. issue 5. 2022-05-06. PMID:35524138. |
together, these data demonstrate that neurotransmitter phenotype of defined excitatory interneurons steers locomotor recovery after spinal cord injury. |
2022-05-06 |
2023-08-13 |
mouse |
| Wayne Barnaby, Hanna E Dorman Barclay, Akanksha Nagarkar, Matthew Perkins, Gregory Teicher, Josef G Trapani, Gerald B Downe. GABAA α Subunit Control of Hyperactive Behavior in Developing Zebrafish. Genetics. 2022-02-02. PMID:35106556. |
gabaa receptors mediate rapid responses to the neurotransmitter gaba and are robust regulators of the brain and spinal cord neural networks that control locomotor behaviors, such as walking and swimming. |
2022-02-02 |
2023-08-13 |
zebrafish |