Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Luke E Osborn, Breanne Christie, David P McMullen, Tessy M Thomas, Margaret C Thompson, Robert W Nickl, Ambarish S Pawar, Brock A Wester, Gabriela L Cantarero, Pablo A Celnik, Nathan E Crone, Matthew S Fifer, Francesco V Tenor. Artificial touch feedback using microstimulation of human somatosensory cortex to convey grip force from a robotic hand. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2024. 2025-03-05. PMID:40039504. |
in a human participant with spinal cord injury and chronically implanted microelectrode arrays, we used icms to the somatosensory cortex to provide grip force feedback in the hands during grasping of objects with varying stiffness with a robotic arm. |
2025-03-05 |
2025-03-07 |
human |
Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulg. Spinally targeted paired associated stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects. Scientific reports. vol 14. issue 1. 2024-12-28. PMID:39730811. |
a novel variant of paired-associative stimulation (pas) consisting of high-frequency peripheral nerve stimulation (pns) and high-intensity transcranial magnetic stimulation (tms) above the motor cortex, called high-pas, can lead to improved motor function in patients with incomplete spinal cord injury. |
2024-12-28 |
2024-12-30 |
human |
Jacques A Rousseau, Marcel Maier, Samia Ait-Mohand, Véronique Dumulon-Perreault, Otman Sarrhini, Sébastien Tremblay, Etienne Rousseau, Michael Salzmann, Brigitte Guéri. Antibody-Based PET Imaging of Misfolded Superoxide Dismutase 1 in an Amyotrophic Lateral Sclerosis Mouse Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024-12-12. PMID:39667814. |
amyotrophic lateral sclerosis (als) is a rare neurodegenerative disease characterized by motor neuron loss in the motor cortex, brain stem, and spinal cord. |
2024-12-12 |
2024-12-22 |
mouse |
Banaja P Dash, Axel Freischmidt, Anika M Helferich, Albert C Ludolph, Peter M Andersen, Jochen H Weishaupt, Andreas Herman. Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients. Frontiers in cellular neuroscience. vol 18. 2024-11-26. PMID:39588282. |
amyotrophic lateral sclerosis (als) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (mns) present in the spinal cord, brain stem and motor cortex. |
2024-11-26 |
2024-11-28 |
Not clear |
Anjali Singh, Khushi, Vinod Tiwari, Alok Kuma. Microparticles Mediate Lipopolysaccharide-induced Inflammation and Chronic Pain in Mouse Model. Neuromolecular medicine. vol 26. issue 1. 2024-11-25. PMID:39585502. |
moreover, upregulation of trpm2, mglur2, and mglur5 was found in the spinal cord, along with increased trpa1 protein expression in the brain cortex. |
2024-11-25 |
2024-11-27 |
mouse |
Nestor I Martínez-Torres, Jhonathan Cárdenas-Bedoya, Blanca Miriam Torres-Mendoz. Cerebrolysin Induces Motor Recovery Along with Plastic Changes in Motoneurons and an Increase in GAP43 Protein in the Ventral Spinal Cord Following a Kainic Acid Excitotoxic Lesion in the Rat Motor Cortex. Neurochemical research. vol 50. issue 1. 2024-11-24. PMID:39580783. |
cerebrolysin induces motor recovery along with plastic changes in motoneurons and an increase in gap43 protein in the ventral spinal cord following a kainic acid excitotoxic lesion in the rat motor cortex. |
2024-11-24 |
2024-11-27 |
rat |
Nestor I Martínez-Torres, Jhonathan Cárdenas-Bedoya, Blanca Miriam Torres-Mendoz. Cerebrolysin Induces Motor Recovery Along with Plastic Changes in Motoneurons and an Increase in GAP43 Protein in the Ventral Spinal Cord Following a Kainic Acid Excitotoxic Lesion in the Rat Motor Cortex. Neurochemical research. vol 50. issue 1. 2024-11-24. PMID:39580783. |
here, the effect of cerebrolysin administration on the motor impairment produced by kainic acid (ka) lesion of the motor cortex was evaluated in sprague-dawley female rats (n = 27), defining its effect on motoneurons dendritic tree changes, dendritic spine density and gap43 presence in the ventral thoracolumbar regions of the spinal cord. |
2024-11-24 |
2024-11-27 |
rat |
Mikaela M Ceder, Kajsa A Magnusson, Hannah M Weman, Katharina Henriksson, Linn Andréasson, Teresa Lindström, Oskar Wiggins, Malin C Lagerströ. The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice. Molecular and cellular neurosciences. 2024-11-23. PMID:39580061. |
(2018) dataset indicated widespread expression of glra1, glra2 and glrb in the cns, while only a few cells in the cortex, striatum, thalamus, midbrain and spinal cord expressed glra4. |
2024-11-23 |
2024-11-26 |
mouse |
Mikaela M Ceder, Kajsa A Magnusson, Hannah M Weman, Katharina Henriksson, Linn Andréasson, Teresa Lindström, Oskar Wiggins, Malin C Lagerströ. The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice. Molecular and cellular neurosciences. 2024-11-23. PMID:39580061. |
lastly, rnascope spatially validated the expression of glra1, glra2 and glrb in the areas indicated by the single-cell and bulk analyses, and further revealed that glra4 can be detected in the cortex, amygdala, hypothalamus, thalamus, brainstem, especially the cochlear nucleus, and in the spinal cord. |
2024-11-23 |
2024-11-26 |
mouse |
Song Luo, Xiaorui Wang, Bo Ma, Dongliang Liu, Li Li, Lijin Wang, Ning Ding, Liangyu Zou, Jie Wang, Jialin Pan, Daoqian Sang, Huadong Zhou, Hongdang Qu, Yi Lu, Lijuan Yan. Therapeutic potential of Simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation. Biomolecules & biomedicine. 2024-11-21. PMID:39569650. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-11-21 |
2024-11-23 |
mouse |
M Khamaysa, M El Mendili, V Marchand, G Querin, P-F Prada. Quantitative spinal cord imaging: Early ALS diagnosis and monitoring of disease progression. Revue neurologique. 2024-11-15. PMID:39547910. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. |
2024-11-15 |
2024-11-18 |
Not clear |
Tereza Filipi, Jana Tureckova, Ondrej Vanatko, Martina Chmelova, Monika Kubiskova, Natalia Sirotova, Stanislava Matejkova, Lydia Vargova, Miroslava Anderov. ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model. Frontiers in cellular neuroscience. vol 18. 2024-10-26. PMID:39449756. |
morphological analysis revealed astrogliosis in both the motor cortex and the ventral horns of the sod1 spinal cord. |
2024-10-26 |
2024-10-28 |
mouse |
Magdalena Chrószcz, Jacek Hajto, Klaudia Misiołek, Łukasz Szumiec, Magdalena Ziemiańska, Anna Radlicka-Borysewska, Małgorzata Borczyk, Mateusz Zięba, Sławomir Gołda, Marcin Siwiec, Barbara Ziółkowska, Marcin Piechota, Michał Korostyński, Jan Rodriguez Parkitn. μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cord. Gene. 2024-08-26. PMID:39187136. |
long-read sequencing confirmed that the final oprm1 exon included a 10.2 kilobase long 3' untranslated region, and the presence of the long variant was unambiguously confirmed using rnascope in situ hybridization in the thalamus, striatum, cortex and spinal cord. |
2024-08-26 |
2024-08-30 |
mouse |
Tian Qin, Yuxin Jin, Yiming Qin, Feifei Yuan, Hongbin Lu, Jianzhong Hu, Yong Cao, Chengjun L. Enhancing m6A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury. Neural regeneration research. vol 20. issue 6. 2024-08-06. PMID:39104113. |
we found that expression of methyltransferase 14 protein (mettl14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m6a levels. |
2024-08-06 |
2024-08-08 |
Not clear |
Tian Qin, Yuxin Jin, Yiming Qin, Feifei Yuan, Hongbin Lu, Jianzhong Hu, Yong Cao, Chengjun L. Enhancing m6A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury. Neural regeneration research. vol 20. issue 6. 2024-08-06. PMID:39104113. |
knockdown of mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. |
2024-08-06 |
2024-08-08 |
Not clear |
Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, Giuseppe Pignatar. Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice. ACS pharmacology & translational science. vol 7. issue 7. 2024-07-18. PMID:39022351. |
the debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons (mns) in the brain, spinal cord, and motor cortex. |
2024-07-18 |
2024-07-20 |
mouse |
Venkataramanan Srinivasan, Victoria Homer, Darren Barton, Abigail Clutterbuck-James, Siân Jenkins, Claire Potter, Kristian Brock, Ann Logan, Donna Smith, Lars Bruce, Zsuzsanna Nagy, Simon P Bac. A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990927. |
it is a fatal disease with specific loss of motor neurons in the spinal cord, brain stem, and motor cortex leading to progressive paralysis and usually death within five years of diagnosis. |
2024-07-11 |
2024-07-14 |
Not clear |
Natalie E Doody, Nicole J Smith, Elizabeth C Akam, Graham N Askew, Jessica C F Kwok, Ronaldo M Ichiyam. Differential expression of genes in the RhoA/ROCK pathway in the hippocampus and cortex following intermittent hypoxia and high intensity interval training. Journal of neurophysiology. 2024-07-10. PMID:38985935. |
we investigated whether the rhoa/rock signaling pathway (known to restrict neuroplasticity) is also modulated by ih and hiit in the hippocampus, cortex, and lumbar spinal cord of male wistar rats. |
2024-07-10 |
2024-07-13 |
rat |
Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. |
amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. |
2024-06-20 |
2024-06-23 |
Not clear |