All Relations between nucleus accumbens and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. 2024-02-20 2024-02-23 rat
Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. 2024-01-10 2024-01-13 mouse
Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Brain structure & function. 2024-01-09. PMID:38193917. novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). 2024-01-09 2024-01-10 rat
Emanuele Claudio Latagliata, Cristina Orsini, Simona Cabib, Francesca Biagioni, Francesco Fornai, Stefano Puglisi-Allegr. Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137410. the reviewed findings point to a role of catecholaminergic transmission in the medial prefrontal cortex (mpfc) in modulating da's availability in the nucleus accumbens (nac), as well as a role of nac da in modulating the motivational value of natural and conditioned stimuli. 2023-12-23 2023-12-25 Not clear
Ki Bum Um, Soyoung Kwak, Sun-Ha Cheon, JuHyun Kim, Su-Kyeong Hwan. AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137504. the core symptoms of asd are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (vta) to the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). 2023-12-23 2023-12-25 mouse
Luis Gerardo Balcazar-Ochoa, Rosa Ventura-Martínez, Guadalupe Esther Ángeles-López, Claudia Gómez-Acevedo, Omar Francisco Carrasco, Raúl Sampieri-Cabrera, Anahí Chavarría, Abimael González-Hernánde. Clavulanic Acid and its Potential Therapeutic Effects on the Central Nervous System. Archives of medical research. vol 55. issue 1. 2023-12-01. PMID:38039802. studies have revealed that clav can increase glt-1 expression in the nucleus accumbens (nacc), medial prefrontal cortex (pfc), and spinal cord of rodents, to affect glutamate and dopaminergic neurotransmission, and exert an anti-inflammatory effect by modulating the levels of the cytokines tnf-α and interleukin 10 (il-10). 2023-12-01 2023-12-10 Not clear
Bing Huang, Zifei Chen, Fang Huang, Fenfei Gao, Jieling Chen, Peipei Liu, Zhijie Lu, Weiyuan Chen, Jie W. Demyelination in the medial prefrontal cortex by withdrawal from chronic nicotine causes impaired cognitive memory. Progress in neuro-psychopharmacology & biological psychiatry. 2023-11-30. PMID:38036034. we found no effect of nicotine withdrawal on the myelination in both of the ventral tegmental area (vta) and nucleus accumbens (nac) regions, but unexpectedly, we observed a demyelination phenomenon in the medial prefrontal cortex (mpfc) after withdrawal from chronic nicotine. 2023-11-30 2023-12-10 Not clear
Yong-Qing Zhang, Hyun Kyu Min, Eunchong Hong, Eunhye Yu, Sun Mi Gu, Seong Shoon Yoon, Dohyun Lee, Jaejun Lee, Jin Tae Hong, Jaesuk Yu. Abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 169. 2023-11-10. PMID:37948992. abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. 2023-11-10 2023-11-20 mouse
Yong-Qing Zhang, Hyun Kyu Min, Eunchong Hong, Eunhye Yu, Sun Mi Gu, Seong Shoon Yoon, Dohyun Lee, Jaejun Lee, Jin Tae Hong, Jaesuk Yu. Abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 169. 2023-11-10. PMID:37948992. we determined dopamine transporter (dat) availability in the medial prefrontal cortex (mpfc), striatum, and nucleus accumbens (nac) after drug treatment. 2023-11-10 2023-11-20 mouse
Joseph S Lonstein, Erika M Vitale, Doris Olekanma, Andrew McLocklin, Nathan Pence, Remco Bredewold, Alexa H Veenema, Alexander W Johnson, S Alexandra Bur. Anxiety, aggression, reward sensitivity, and forebrain dopamine receptor expression in a laboratory rat model of early-life disadvantage. Developmental psychobiology. vol 65. issue 7. 2023-10-20. PMID:37860907. d1 and d2 receptor mrna in the medial prefrontal cortex and nucleus accumbens (nac) were each affected by the early-life treatments and differently between the sexes. 2023-10-20 2023-11-08 rat
Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Research square. 2023-10-04. PMID:37790415. novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). 2023-10-04 2023-10-07 rat
Désirée R Seib, Daniel J Tobiansky, John Meitzen, Stan B Floresco, Kiran K Som. Neurosteroids and the mesocorticolimbic system. Neuroscience and biobehavioral reviews. 2023-08-11. PMID:37567491. this circuit includes dopaminergic projections from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex. 2023-08-11 2023-08-16 Not clear
Giuseppe Tringali, Gianluca Lavanco, Valentina Castelli, Giuseppe Pizzolanti, Martin Kuchar, Diego Currò, Carla Cannizzaro, Anna Brancat. Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking  adolescent rats. Focus on calcitonin gene-related peptide's brain levels. Phytotherapy research : PTR. 2023-08-01. PMID:37525534. adolescent male rats underwent the intermittent 20% alcohol two-bottle choice paradigm; at the binge day (bd) and the 24 h withdrawal day (wd), we assessed cgrp expression in medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, hypothalamus and brainstem; in addition, we evaluated sucrose preference, social motivation and drive, nociceptive response, and serum corticosterone levels. 2023-08-01 2023-08-14 rat
Courtney S Wilkinson, Harrison L Blount, Marek Schwendt, Lori A Knacksted. Brain Monoamine Dysfunction in Response to Predator Scent Stress Accompanies Stress-Susceptibility in Female Rats. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509091. using a predator scent stress (pss) rodent model of ptsd, we sought to determine if stress-susceptible female rats show altered monoamine concentrations in brain regions associated with ptsd: the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and dorsal (dhipp) and ventral (vhipp) hippocampus. 2023-07-29 2023-08-14 rat
Julie-Anne Balouek, Christabel A Mclain, Adelaide R Minerva, Rebekah L Rashford, Shannon N Bennett, Forrest D Rogers, Catherine Jensen Peñ. Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-10. PMID:37429717. we found that in both male and female mice, els-activated neurons within the nucleus accumbens (nac), and to a lesser-extent the medial prefrontal cortex, were preferentially reactivated by adult stress. 2023-07-10 2023-08-14 mouse
Yuan-Yuan Han, Jian-Wen Zhou, Zhi-Wei Guo, Zhuo-Qing Wu, Zai-Yong Zhang, De-Xiang Liu, Cheng Lon. Multiple brain regions are involved in reaction to acute restraint stress in CYLD-knockout mice. Stress (Amsterdam, Netherlands). vol 26. issue 1. 2023-07-03. PMID:37395260. here we report that cyld deficiency leads to an unexpected reaction to ars in mice, and is accompanied by significant neuronal activation of brain regions including the medial prefrontal cortex (mpfc), dorsal striatum (ds), nucleus accumbens (nac), and basal lateral amygdala (bla), but not ventral hippocampus (vhpc). 2023-07-03 2023-08-14 mouse
Robert J McDonald, Nancy S Hong, Carlie Germaine, Bryan Kol. Peripherally-administered amphetamine induces plasticity in medial prefrontal cortex and nucleus accumbens in rats with amygdala lesions: implications for neural models of memory modulation. Frontiers in behavioral neuroscience. vol 17. 2023-06-27. PMID:37358968. peripherally-administered amphetamine induces plasticity in medial prefrontal cortex and nucleus accumbens in rats with amygdala lesions: implications for neural models of memory modulation. 2023-06-27 2023-08-14 rat
Wei-Zhu Liu, Chun-Yan Wang, Yu Wang, Mei-Ting Cai, Wei-Xiang Zhong, Tian Liu, Zhi-Hao Wang, Han-Qing Pan, Wen-Hua Zhang, Bing-Xing Pa. Circuit- and laminar-specific regulation of medial prefrontal neurons by chronic stress. Cell & bioscience. vol 13. issue 1. 2023-05-19. PMID:37208769. the medial prefrontal cortex (mpfc) is a hub for controlling stress responses through communicating with multiple limbic structures, including the basolateral amygdala (bla) and nucleus accumbens (nac). 2023-05-19 2023-08-14 Not clear
F Javier Rubio, Daniel E Olivares, Christopher Dunn, Shiliang Zhang, Elias M Hilaire, Akeem Henry, Carlos Mejias-Aponte, Carlos J Nogueras-Ortiz, Pooja V Selvam, Fabio C Cruz, Rajtarun Madangopal, Marisela Morales, Bruce T Hop. Flow cytometry of synaptoneurosomes (FCS) reveals increased ribosomal S6 and calcineurin proteins in activated medial prefrontal cortex to nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-09. PMID:37160369. after injecting yfp-expressing aav into medial prefrontal cortex (mpfc) to label terminals in nucleus accumbens (nac) of rats, we injected 20 mg/kg of cocaine in a novel context (cocaine+novelty) to activate synapses, and prepared nac synaptoneurosomes 0-60 min following injections. 2023-05-09 2023-08-14 rat
María Del Mar Cajiao-Manrique, Rafael Maldonado, Elena Martín-Garcí. A male mouse model of WIN 55,212-2 self-administration to study cannabinoid addiction. Frontiers in pharmacology. vol 14. 2023-04-13. PMID:37050910. this model included the chemogenetic inhibition of neuronal activity in the medial prefrontal cortex to the nucleus accumbens pathway to assess the neurobiological substrate of cannabinoid addiction. 2023-04-13 2023-08-14 mouse