| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |
| Andrea R Hamilton, Abhilasha Vishwanath, Nathan C Weintraub, Stephen L Cowen, M Leandro Heie. Dopamine Release Dynamics in the Nucleus Accumbens Are Modulated by the Timing of Electrical Stimulation Pulses When Applied to the Medial Forebrain Bundle and Medial Prefrontal Cortex. ACS chemical neuroscience. 2024-07-03. PMID:38958080. |
dopamine release dynamics in the nucleus accumbens are modulated by the timing of electrical stimulation pulses when applied to the medial forebrain bundle and medial prefrontal cortex. |
2024-07-03 |
2024-07-06 |
Not clear |
| Ahmed Alotaibi, Shelby Travaglianti, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of MC-100093 on ethanol drinking and the expression of astrocytic glutamate transporters in the mesocorticolimbic brain regions of male and female alcohol-preferring rats. Neuroscience. 2024-06-23. PMID:38909675. |
in this study, we aimed to determine the attenuating effects of a novel beta-lactam mc-100093, lacking the antibacterial properties, on ethanol consumption and glt-1 and xct expression in the subregions of nucleus accumbens (nac core and nac shell) and medial prefrontal cortex (infralimbic, mpfc-il and prelimbic, mpfc-pl) in male and female alcohol-preferring (p) rats. |
2024-06-23 |
2024-06-26 |
rat |
| Simin Deng, Si Tan, Cuihua Guo, Yanxiong Liu, Xiuhong L. Impaired effective functional connectivity in the social preference of children with autism spectrum disorder. Frontiers in neuroscience. vol 18. 2024-06-14. PMID:38872942. |
the medial prefrontal cortex (mpfc), amygdala (amyg), and nucleus accumbens (nac) have been identified as critical players in the social preference of individuals with asd. |
2024-06-14 |
2024-06-16 |
Not clear |
| Pan Xu, Gyeongah Park, Xiaoqian Sun, Qian Ge, Zhen Jin, Chien-Hsien Lai, Xiaojie Liu, Qingsong Liu, Rahul Simha, Chen Zeng, Jianyang Du, Hui L. Different emotional states engage distinct descending pathways from the prefrontal cortex. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853906. |
using in vivo calcium imaging, electrophysiology, and optogenetics, we examined neural circuit dynamics in the medial prefrontal cortex (mpfc), targeting two key areas: the basal lateral amygdala (bla) and nucleus accumbens (nac). |
2024-06-10 |
2024-06-14 |
Not clear |
| Shu-Chuan Yang, Kun-Ruey Shie. Higher exploratory and vigilant behaviors related to higher central dopaminergic activities of Formosan wood mice (Apodemus semotus) in light-dark exploration tests. Pharmacology, biochemistry, and behavior. 2024-05-28. PMID:38806117. |
we also measured the levels of da and 3,4-dihydroxyphenylacetic acid (dopac), the primary metabolite of da, to assess the dopaminergic activity of the medial prefrontal cortex, striatum, and nucleus accumbens. |
2024-05-28 |
2024-06-03 |
mouse |
| Bo W Sortman, Samantha Rakela, Sarah Paprotna, Berk Cerci, Brandon L Warre. Nucleus accumbens neuronal ensembles vary with cocaine reinforcement in male and female rats. Addiction biology. vol 29. issue 5. 2024-05-07. PMID:38711205. |
neuronal ensembles in the medial prefrontal cortex mediate cocaine self-administration via projections to the nucleus accumbens. |
2024-05-07 |
2024-05-27 |
rat |
| Mark D Namba, Qiaowei Xie, Kyewon Park, Joshua G Jackson, Jacqueline M Barke. EcoHIV Infection Modulates the Effects of Cocaine Exposure Pattern and Abstinence on Cocaine Seeking and Neuroimmune Protein Expression in Male Mice. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659915. |
analysis of corticolimbic cx3cl1-cx3cr1 and glutamate receptor expression revealed alterations in medial prefrontal cortex (mpfc) cx3cl1 and nucleus accumbens (nac) glun2a receptors that correlated with cocaine seeking following daily cocaine exposure. |
2024-04-25 |
2024-04-28 |
mouse |
| Kevin Braunscheidel, Michael Okas, John J Woodwar. Toluene alters the intrinsic excitability and excitatory synaptic transmission of basolateral amygdala neurons. Frontiers in neuroscience. vol 18. 2024-04-10. PMID:38595974. |
however, studies from our lab and others have begun to reveal how inhalants such as the organic solvent toluene affect neurons in key addiction related areas of the brain including the ventral tegmental area, nucleus accumbens and medial prefrontal cortex. |
2024-04-10 |
2024-04-12 |
Not clear |
| Chengmei Yang, Xiaoyu Chen, Jingyang Xu, Weihai Che. SKF82958, a dopamine D1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in C57BL/6J mice. Behavioural pharmacology. 2024-04-03. PMID:38567425. |
skf82958, a dopamine d1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in c57bl/6j mice. |
2024-04-03 |
2024-04-05 |
mouse |
| Chengmei Yang, Xiaoyu Chen, Jingyang Xu, Weihai Che. SKF82958, a dopamine D1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in C57BL/6J mice. Behavioural pharmacology. 2024-04-03. PMID:38567425. |
overall, the study suggests that the nucleus accumbens and medial prefrontal cortex are responsible for the ppi-disruptive effect of dopamine d1 receptor agonists. |
2024-04-03 |
2024-04-05 |
mouse |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Qiong Luo, Jing Luo, Xixi Wang, Sifei Ga. Restoration of the Activity of the Prefrontal Cortex to the Nucleus Accumbens Core Pathway Relieves Fentanyl-Induced Hyperalgesia in Male Rats. Journal of pain research. vol 17. 2024-03-25. PMID:38524691. |
functional connectivity between the prelimbic medial prefrontal cortex (pl-mpfc) and the core of the nucleus accumbens (nac core) predicts pain chronification. |
2024-03-25 |
2024-03-27 |
rat |
| Tsun Hay Jason Ng, Mohammed H Sarikahya, Roger Hudson, Hanna J Szkudlarek, Enzo Pérez-Valenzuela, Taygun C Uzuneser, Emma Proud, Dana Gummerson, Miray Youssef, Madeline Machado, Kuralay Zhaksylyk, Marieka V DeVuono, Chaochao Chen, Ken K-C Yeung, Walter J Rushlow, Steven R Laviolett. Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-24. PMID:38521861. |
specifically, brain regions such as the medial prefrontal cortex (mpfc), the ventral tegmental area (vta), nucleus accumbens (nac) and hippocampus, are implicated in both nicotine dependence and pathological phenotypes linked to mood and anxiety disorders. |
2024-03-24 |
2024-03-26 |
rat |
| Ioannis Bakoyiannis, Eva Gunnel Ducourneau, Mateo N'diaye, Alice Fermigier, Celine Ducroix-Crepy, Clementine Bosch-Bouju, Etienne Coutureau, Pierre Trifilieff, Guillaume Ferreir. Obesogenic diet induces circuit-specific memory deficits in mice. eLife. vol 13. 2024-03-04. PMID:38436653. |
here, we used an intersectional viral approach in hfd-fed male mice to chemogenetically inactivate specific vhpc efferent pathways to nucleus accumbens (nac) or medial prefrontal cortex (mpfc) during memory tasks. |
2024-03-04 |
2024-03-06 |
mouse |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. |
analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. |
2024-01-10 |
2024-01-13 |
mouse |
| Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Brain structure & function. 2024-01-09. PMID:38193917. |
novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). |
2024-01-09 |
2024-01-10 |
rat |
| Emanuele Claudio Latagliata, Cristina Orsini, Simona Cabib, Francesca Biagioni, Francesco Fornai, Stefano Puglisi-Allegr. Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137410. |
the reviewed findings point to a role of catecholaminergic transmission in the medial prefrontal cortex (mpfc) in modulating da's availability in the nucleus accumbens (nac), as well as a role of nac da in modulating the motivational value of natural and conditioned stimuli. |
2023-12-23 |
2023-12-25 |
Not clear |
| Ki Bum Um, Soyoung Kwak, Sun-Ha Cheon, JuHyun Kim, Su-Kyeong Hwan. AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137504. |
the core symptoms of asd are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (vta) to the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2023-12-23 |
2023-12-25 |
mouse |