| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |
| Spencer B Huggett, Sharmila Selveraj, John E McGeary, Ami Ikeda, Emerald Yuan, Lauren B Loeffel, Rohan H C Palme. Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005451. |
this study explores the neurobiological underpinnings of alcohol use disorder (aud) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (pfc), nucleus accumbens (nac), and central amygdala (cea)). |
2024-07-15 |
2024-07-18 |
mouse |
| Laszlo Peczely, Anthony A Grac. The dose-dependent effect of the D2R agonist quinpirole microinjected into the ventral pallidum on information flow in the limbic system. Progress in neuro-psychopharmacology & biological psychiatry. 2024-06-20. PMID:38901759. |
the ventral pallidum (vp) receives its primary inputs from the nucleus accumbens (nac) and the basolateral amygdala (bla). |
2024-06-20 |
2024-06-23 |
Not clear |
| Avril Gagnon-Chauvin, Mathieu Fornasier-Bélanger, Sandra W Jacobson, Joseph L Jacobson, Yohann Courtemanche, Pierre Ayotte, Richard E Bélanger, Gina Muckle, Dave Saint-Amou. Brain gray matter volume of reward-related structures in Inuit adolescents pre- and postnatally exposed to lead, mercury and polychlorinated biphenyls. Neurotoxicology. 2024-06-16. PMID:38880197. |
this study aimed to assess associations between prenatal and postnatal exposure to lead (pb), mercury (hg) and polychlorinated biphenyls (pcbs) and gray matter volume of key regions of the brain reward circuit, namely the caudate nucleus, putamen, nucleus accumbens (nacc), the amygdala, the orbitofrontal cortex (ofc) and the anterior cingulate cortex (acc). |
2024-06-16 |
2024-06-19 |
Not clear |
| Simin Deng, Si Tan, Cuihua Guo, Yanxiong Liu, Xiuhong L. Impaired effective functional connectivity in the social preference of children with autism spectrum disorder. Frontiers in neuroscience. vol 18. 2024-06-14. PMID:38872942. |
the medial prefrontal cortex (mpfc), amygdala (amyg), and nucleus accumbens (nac) have been identified as critical players in the social preference of individuals with asd. |
2024-06-14 |
2024-06-16 |
Not clear |
| L van Drunen, S Dobbelaar, E A Crone, L M Wiereng. Genetic and environmental influences on structural brain development from childhood to adolescence: A longitudinal twin study on cortical thickness, surface area, and subcortical volume. Developmental cognitive neuroscience. vol 68. 2024-06-13. PMID:38870602. |
heritability estimates varied across brain regions, with all regions showing genetic influence (ranging from 18 % to 59 %) with additional shared environmental factors affecting the primary motor cortex (30 %), somatosensory cortex (35 %), dlpfc (5 %), tpj (17 %), sts (17 %), precuneus (10 %), hippocampus (22 %), amygdala (5 %), and nucleus accumbens (10 %). |
2024-06-13 |
2024-06-16 |
human |
| Justin P Yuan, Emma L Jaeger, Saché M Coury, Jessica P Uy, Jessica L Buthmann, Tiffany C Ho, Ian H Gotli. Socioeconomic Disadvantage Moderates the Association of Systemic Inflammation with Amygdala Volume in Adolescents Over a Two-Year Interval: An Exploratory Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2024-06-11. PMID:38815859. |
affective areas of the brain involved in processing threat (e.g., amygdala) and reward (e.g., nucleus accumbens [nacc]) appear to be sensitive to inflammation. |
2024-06-11 |
2024-06-14 |
Not clear |
| Pan Xu, Gyeongah Park, Xiaoqian Sun, Qian Ge, Zhen Jin, Chien-Hsien Lai, Xiaojie Liu, Qingsong Liu, Rahul Simha, Chen Zeng, Jianyang Du, Hui L. Different emotional states engage distinct descending pathways from the prefrontal cortex. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853906. |
using in vivo calcium imaging, electrophysiology, and optogenetics, we examined neural circuit dynamics in the medial prefrontal cortex (mpfc), targeting two key areas: the basal lateral amygdala (bla) and nucleus accumbens (nac). |
2024-06-10 |
2024-06-14 |
Not clear |
| Isabel C Duarte, Ana Dionísio, Joana Oliveira, Marco Simões, Rita Correia, Joana A Dias, Salomé Caldeira, João Redondo, Miguel Castelo-Branc. Neural underpinnings of ethical decisions in life and death dilemmas in naïve and expert firefighters. Scientific reports. vol 14. issue 1. 2024-06-08. PMID:38851794. |
these realistic life-saving dilemmas activate the same core reward and affective processing network, in particular the ventromedial prefrontal cortex, nucleus accumbens and amygdala, irrespective of prior expertise, thereby supporting general domain theories of ethical decision-making. |
2024-06-08 |
2024-06-11 |
Not clear |
| Vladimir Visocky, Carleigh J Turner, Matthew H Lowrie, Anthony Alibro, Fany Messanvi, Yogita Chudasam. Noradrenergic modulation of stress induced catecholamine release: Opposing influence of FG7142 and yohimbine. bioRxiv : the preprint server for biology. 2024-05-26. PMID:38766011. |
the basolateral amygdala (bla) and nucleus accumbens (nac) are stress sensitive brain areas that alter extracellular levels of norepinephrine (ne) and dopamine (da), respectively. |
2024-05-26 |
2024-05-27 |
rat |
| Lu Liu, Jie Wu, Changlin Zhang, Tong Cao, Yongli Lu, Zhi He, Zicheng L. Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice. Brain research. 2024-04-11. PMID:38604556. |
(2) the endoplasmic reticulum stress-related proteins in the lateral habenula (lhb) but not in the nucleus accumbens (nac), ventral pallidum (vp), basolateral amygdala (bla) and ca1 of hippocampus was upregulated by morphine withdrawal, upregulation of endoplasmic reticulum stress-related proteins in the lateral habenula induced by morphine withdrawal was inhibited by 4-pba. |
2024-04-11 |
2024-04-14 |
mouse |
| Trevor T Towner, Devon T Applegate, Harper J Coleman, Elena I Varlinskaya, David F Werne. Patterns of neuronal activation following ethanol-induced social facilitation and social inhibition in adolescent cFos-LacZ male and female rats. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559141. |
however, hub analyses converged on similar brain regions in males and females, with the nucleus accumbens being a hub region in socially inhibited subjects, whereas the central amygdala was disconnected in facilitated subjects. |
2024-04-01 |
2024-04-04 |
human |
| Yingying Chen, Xiaodi Xia, Zheyi Zhou, Meng Yuan, Yadong Peng, Ying Liu, Jinxiang Tang, Yixiao F. Interleukin-6 is correlated with amygdala volume and depression severity in adolescents and young adults with first-episode major depressive disorder. Brain imaging and behavior. 2024-03-12. PMID:38467915. |
in this study, we aimed to investigate the potential correlations among cytokines, depression severity, and the volumes of the amygdala, hippocampus, and nucleus accumbens in han chinese adolescents and young adults with first-episode mdd. |
2024-03-12 |
2024-03-14 |
Not clear |
| Anna C Cichocki, Richard E Zinbarg, Michelle G Craske, Iris K-Y Chat, Katherine S Young, Susan Y Bookheimer, Robin Nussloc. Transdiagnostic symptom of depression and anxiety associated with reduced gray matter volume in prefrontal cortex. Psychiatry research. Neuroimaging. vol 339. 2024-02-15. PMID:38359709. |
using structural mri, gray matter volumes were extracted for emotion generation (amygdala, nucleus accumbens) and regulation (orbitofrontal, ventrolateral, and dorsolateral prefrontal cortex) regions, often implicated in depression and anxiety. |
2024-02-15 |
2024-02-18 |
Not clear |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
similar reversal effects of fluoxetine and vortioxetine were observed, including sert in the amygdala and net in the mpfc, whereas different reversal effects were observed for net in the hippocampus and vesicular monoamine transporters expression in the nucleus accumbens. |
2024-02-09 |
2024-02-12 |
mouse |
| Giulia Poggi, Giorgio Bergamini, Redas Dulinskas, Lorraine Madur, Alexandra Greter, Christian Ineichen, Amael Dagostino, Diana Kúkeľová, Hannes Sigrist, Klaus D Bornemann, Bastian Hengerer, Christopher R Pryc. Engagement of basal amygdala-nucleus accumbens glutamate neurons in the processing of rewarding or aversive social stimuli. The European journal of neuroscience. 2024-02-07. PMID:38326849. |
basal amygdala (ba) neurons projecting to nucleus accumbens (nac) core/shell are primarily glutamatergic and are integral to the circuitry of emotional processing. |
2024-02-07 |
2024-02-10 |
mouse |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
the pathophysiology of depression is related to the reduced volume of the hippocampus and amygdala and hypertrophy of the nucleus accumbens. |
2024-01-11 |
2024-01-13 |
rat |
| Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Brain structure & function. 2024-01-09. PMID:38193917. |
novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). |
2024-01-09 |
2024-01-10 |
rat |
| Acácio Moreira-Neto, Lucas Melo Neves, Angelo Miliatto, Valeria Juday, Raquel Marquesini, Beny Lafer, Ellison Fernando Cardoso, Carlos Ugrinowitsch, Mariana Penteado Nucci, Carla Silva-Batist. Clinical and neuroimaging correlates in a pilot randomized trial of aerobic exercise for major depression. Journal of affective disorders. vol 347. 2023-12-14. PMID:38092282. |
aerobic exercise (ae) combined with pharmacotherapy is known to reduce depressive symptoms; however, studies have not focused on long-term ae for volumetric changes of brain regions (amygdala, thalamus, and nucleus accumbens [nacc]) linked to the control of affective responses and hopelessness in individuals with major depression (md). |
2023-12-14 |
2023-12-17 |
Not clear |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |