All Relations between mesencephalon and cerebral cortex

Publication Sentence Publish Date Extraction Date Species
Anastasia Gaspert, Rasmus Schülke, Zeinab Houjaije, Tabea Bätge, Christopher Sinke, Nima Mahmoudi, Thorsten Folsche, Alborz Bastami, Alexandra Neyazi, Mike P Wattjes, Tillmann H C Krüger, Stefan Bleich, Helge Frieling, Hannah Benedictine Maie. Increased functional connectivity between brainstem substructures and cortex in treatment resistant depression. Psychiatry research. Neuroimaging. vol 348. 2025-02-05. PMID:39908872. interestingly, in trd patients, fc between midbrain and cortex was negatively correlated with bdi-ii scores, indicating a relationship between altered connectivity and self-reported depression severity. 2025-02-05 2025-02-08 Not clear
Liqiang Chen, Hiba Douja Chehade, Hong-Yuan Ch. Motor cortical neuronal hyperexcitability associated with α-synuclein aggregation. NPJ Parkinson's disease. vol 11. issue 1. 2025-01-14. PMID:39809792. to begin to address this question, we injected α-synuclein (αsyn) preformed fibrils (pffs) into the dorsolateral striatum of mice to seed αsyn pathology in the cortical cortex and induce degeneration of midbrain dopaminergic neurons. 2025-01-14 2025-01-17 mouse
Zuzana Bacova, Tomas Havranek, Denisa Mihalj, Veronika Borbelyova, Kristina Kostrubanicova, Michaela Kramarova, Daniela Ostatnikova, Jan Bako. Reduced Neurite Arborization in Primary Dopaminergic Neurons in Autism-Like Shank3B-Deficient Mice. Molecular neurobiology. 2024-12-09. PMID:39654001. despite many studies on dopamine changes in autism, specific alterations in midbrain dopamine neurons projecting to the striatum and cortex remain unclear. 2024-12-09 2024-12-12 mouse
Mikaela M Ceder, Kajsa A Magnusson, Hannah M Weman, Katharina Henriksson, Linn Andréasson, Teresa Lindström, Oskar Wiggins, Malin C Lagerströ. The mRNA expression profile of glycine receptor subunits alpha 1, alpha 2, alpha 4 and beta in female and male mice. Molecular and cellular neurosciences. 2024-11-23. PMID:39580061. (2018) dataset indicated widespread expression of glra1, glra2 and glrb in the cns, while only a few cells in the cortex, striatum, thalamus, midbrain and spinal cord expressed glra4. 2024-11-23 2024-11-26 mouse
Audrey Mercer, Marco Sancandi, Amy Maclatchy, Sigrun Lang. Brain-Region-Specific Differences in Protein Citrullination/Deimination in a Pre-Motor Parkinson's Disease Rat Model. International journal of molecular sciences. vol 25. issue 20. 2024-10-26. PMID:39456949. six brain regions (cortex, hippocampus, striatum, midbrain, cerebellum and olfactory bulb) were compared between controls/shams and the pre-motor pd model. 2024-10-26 2024-10-29 human
Heather Lynne Kosakowski, Mark Eldaief, Randy L Buckne. Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416211. the ventral striatum (vs) receives input from the cerebral cortex and is modulated by midbrain dopaminergic projections in support of processing reward and motivation. 2024-10-17 2024-10-19 human
Hong-Yuan Chu, Liqiang Chen, Hiba Douja Chehad. Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation. Research square. 2024-09-16. PMID:39281856. to begin to address these questions, we injected α-synuclein (αsyn) preformed fibrils (pffs) into the dorsolateral striatum of mice to seed αsyn pathology in the cortical cortex and induce degeneration of midbrain dopaminergic neurons. 2024-09-16 2024-09-19 mouse
Giuseppe D Ciccotosto, Ali I Mohammed, Rita Paolini, Elly Bijlsma, Su Toulson, James Holden, Eric C Reynolds, Stuart G Dashper, Catherine A Butle. Chronic Oral Inoculation of Porphyromonas gingivalis and Treponema denticola Induce Different Brain Pathologies in a Mouse Model of Alzheimer Disease. The Journal of infectious diseases. vol 230. issue Supplement_2. 2024-09-10. PMID:39255392. p. gingivalis alone significantly increased all 7 brain pathologies examined: neuronal damage, activation of astrocytes and microglia, expression of inflammatory cytokines interleukin 1β (il-1β) and interleukin 6 and production of amyloid-β plaques and hyperphosphorylated tau, in the hippocampus, cortex and midbrain, compared to control mice. 2024-09-10 2024-09-13 mouse
Giuseppe D Ciccotosto, Ali I Mohammed, Rita Paolini, Elly Bijlsma, Su Toulson, James Holden, Eric C Reynolds, Stuart G Dashper, Catherine A Butle. Chronic Oral Inoculation of Porphyromonas gingivalis and Treponema denticola Induce Different Brain Pathologies in a Mouse Model of Alzheimer Disease. The Journal of infectious diseases. vol 230. issue Supplement_2. 2024-09-10. PMID:39255392. t. denticola alone significantly increased neuronal damage, activation of astrocytes and microglia, and expression of il-1β, in the hippocampus, cortex and midbrain, compared to control mice. 2024-09-10 2024-09-13 mouse
Giuseppe D Ciccotosto, Ali I Mohammed, Rita Paolini, Elly Bijlsma, Su Toulson, James Holden, Eric C Reynolds, Stuart G Dashper, Catherine A Butle. Chronic Oral Inoculation of Porphyromonas gingivalis and Treponema denticola Induce Different Brain Pathologies in a Mouse Model of Alzheimer Disease. The Journal of infectious diseases. vol 230. issue Supplement_2. 2024-09-10. PMID:39255392. coinoculation of p. gingivalis with t. denticola significantly increased activation of astrocytes and microglia in the hippocampus, cortex and midbrain, and increased production of hyperphosphorylated tau and il-1β in the hippocampus only. 2024-09-10 2024-09-13 mouse
Liqiang Chen, Hiba Douja Chehade, Hong-Yuan Ch. Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation. bioRxiv : the preprint server for biology. 2024-08-02. PMID:39091827. to begin to address these questions, we injected α-synuclein (αsyn) preformed fibrils (pffs) into the dorsolateral striatum of mice to seed αsyn pathology in the cortical cortex and induce degeneration of midbrain dopaminergic neurons. 2024-08-02 2024-08-05 mouse
Hynek Mácha, Dominika Luptáková, Ivo Juránek, Per E Andrén, Vladimír Havlíče. Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions. ACS chemical neuroscience. 2024-07-26. PMID:39058922. specifically, putrescine, cadaverine, and 3-aminopropanal increased significantly as early as 12 h postinsult, mainly in motor and somatosensory cortex, hippocampus, and midbrain, followed by an increase in norepinephrine 24 h postinsult, which was predominant in the caudate putamen, the region most vulnerable to hi. 2024-07-26 2024-07-29 rat
Chao Zhang, R Michael Burge. Cholinergic modulation in the vertebrate auditory pathway. Frontiers in cellular neuroscience. vol 18. 2024-07-04. PMID:38962512. in this review, we highlight what is known about cholinergic function throughout the auditory system from the ear to the cortex, but with a particular emphasis on brainstem and midbrain auditory centers. 2024-07-04 2024-07-10 Not clear
Tousif Jamal, Xuan Yan, Angelica da Silva Lantyer, Judith G Ter Horst, Tansu Celike. Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex. Progress in neurobiology. 2024-06-04. PMID:38834131. these findings suggest that the dopaminergic drive originating from midbrain dopaminergic neurons, targeting the sensory cortex, is subject to experience-dependent regulation and might create a regulatory feed- back loop for modulating sensory processing. 2024-06-04 2024-06-07 human
Elise E Dunning, Boris Decourt, Nasser H Zawia, Holly A Shill, Marwan N Sabbag. Pharmacotherapies for the Treatment of Progressive Supranuclear Palsy: A Narrative Review. Neurology and therapy. 2024-05-14. PMID:38743312. progressive supranuclear palsy (psp) is a neurodegenerative disorder resulting from the deposition of misfolded and neurotoxic forms of tau protein in specific areas of the midbrain, basal ganglia, and cortex. 2024-05-14 2024-05-27 Not clear
Sarah E Gartside, Bas Mj Olthof, Adrian Ree. Motor, somatosensory, and executive cortical areas elicit monosynaptic and polysynaptic neuronal activity in the auditory midbrain. Hearing research. vol 447. 2024-04-26. PMID:38670009. we recently reported that the central nucleus of the inferior colliculus (the auditory midbrain) is innervated by glutamatergic pyramidal cells originating not only in auditory cortex (ac), but also in multiple 'non-auditory' regions of the cerebral cortex. 2024-04-26 2024-04-29 rat
Aggeliki Dimopoulou, Vasiliki Panagiotakopoulou, Theodora Mourtzi, Ilias Kazanis, Fevronia Angelato. Alpha-synuclein pathology in the "weaver" mouse, a genetic model of dopaminergic denervation. microPublication biology. vol 2024. 2024-03-29. PMID:38550606. our results revealed increased serine 129 phosphorylation in the midbrain, striatum, and cortex at a phase of established dopaminergic degeneration on postnatal day 100. 2024-03-29 2024-03-31 mouse
Yan-Feng Zhang, John N J Reynold. The Integration of Top-down and Bottom-up Inputs to the Striatal Cholinergic Interneurons. Current neuropharmacology. 2024-02-29. PMID:38420787. although chis receive extensive top-down inputs from the cortex and bottom-up inputs from the thalamus and midbrain, it is unclear which inputs are involved in the development of chi multiphasic activity. 2024-02-29 2024-03-02 Not clear
Daniel Reumann, Christian Krauditsch, Maria Novatchkova, Edoardo Sozzi, Sakurako Nagumo Wong, Michael Zabolocki, Marthe Priouret, Balint Doleschall, Kaja I Ritzau-Reid, Marielle Piber, Ilaria Morassut, Charles Fieseler, Alessandro Fiorenzano, Molly M Stevens, Manuel Zimmer, Cedric Bardy, Malin Parmar, Jürgen A Knoblic. In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids. Nature methods. 2023-12-05. PMID:38052989. ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are involved in movement control and reward-related cognition. 2023-12-05 2023-12-10 human
Heidi Kleven, Ingvild E Bjerke, Francisco Clascá, Henk J Groenewegen, Jan G Bjaalie, Trygve B Leergaar. Waxholm Space atlas of the rat brain: a 3D atlas supporting data analysis and integration. Nature methods. 2023-10-02. PMID:37783883. it provides a detailed map of the cerebral cortex, hippocampal region, striatopallidal areas, midbrain dopaminergic system, thalamic cell groups, the auditory system and main fiber tracts. 2023-10-02 2023-10-07 rat