| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tony Zhang, Sara J Hooshmand, Nathaniel P Rogers, David O Sohutskay, Michel Toledano, Ajay A Madhavan, John L Atkinson, Jeremy L Fogelson, Alejandro A Rabinstein, Jeremy K Cutsforth-Gregory, Rafid Mustaf. Reversal of Coma With Trendelenburg Position in Spontaneous Intracranial Hypotension. Mayo Clinic proceedings. 2025-04-08. PMID:40196971. |
whereas the hallmark clinical feature of sih is orthostatic headache, in rare instances, life-threatening complications may include altered consciousness and even coma as a result of extreme downward displacement of the midbrain and brainstem. |
2025-04-08 |
2025-04-10 |
Not clear |
| Olivia E Rowe, D Rangaprakash, Florian S Eichler, Jeremy D Schmahmann, Robert L Barry, Christopher D Stephe. Brainstem Substructure Atrophy in Late-Onset GM2-Gangliosidosis Imaging Using Automated Segmentation. Cerebellum (London, England). vol 24. issue 2. 2025-02-19. PMID:39966257. |
a freesurfer brainstem substructure module was used for automatic segmentation and included the pons, medulla, superior cerebellar peduncle (scp), midbrain, and total brainstem. |
2025-02-19 |
2025-02-23 |
Not clear |
| Abigail Orvi. Putting the Puzzle Together: Case Report of Parinaud Syndrome in a Pediatric Patient. Journal of binocular vision and ocular motility. vol 74. issue 4. 2025-01-30. PMID:39882639. |
parinaud syndrome, also known as dorsal midbrain syndrome, is a condition affecting the dorsal midbrain region of the brainstem that presents with a triad of ophthalmic clinical findings, including upgaze paresis, convergence retraction nystagmus, and light-near dissociation. |
2025-01-30 |
2025-02-01 |
Not clear |
| Yeo-Jin Yi, Michael C Kreißl, Oliver Speck, Emrah Düzel, Dorothea Hämmere. Decoding Salience: A Functional Magnetic Resonance Imaging Investigation of Reward and Contextual Unexpectedness in Memory Encoding and Retrieval. Human brain mapping. vol 46. issue 1. 2025-01-07. PMID:39764707. |
by using advanced image processing techniques tailored to examine midbrain and brainstem nuclei with high precision, our study additionally aimed to elucidate differential activation patterns in subcortical nuclei in response to reward-associated and contextually unexpected stimuli, including distinct pathways involving in particular dopaminergic modulation. |
2025-01-07 |
2025-01-13 |
human |
| Martin Pastre, Bob-Valéry Occéan, Vincent Boudousq, Ismael Conejero, Pascale Fabbro-Peray, Laurent Collombier, Luc Mallet, Jorge Lopez-Castroma. Serotonergic underpinnings of obsessive-compulsive disorder: A systematic review and meta-analysis of neuroimaging findings. Psychiatry and clinical neurosciences. 2024-11-08. PMID:39511769. |
patients with ocd showed lower sert binding potential in the brainstem (smd = -1.13, 95% ci [-1.81 to -0.46]), midbrain (smd = -0.54, 95% ci [-0.92 to -0.16]), and thalamus/hypothalamus regions (smd = -0.58, 95% ci [-0.99 to -0.18]) with neglectable to moderate heterogeneity. |
2024-11-08 |
2024-11-16 |
Not clear |
| Catarina Rua, Betty Raman, Christopher T Rodgers, Virginia F J Newcombe, Anne Manktelow, Doris A Chatfield, Stephen J Sawcer, Joanne G Outtrim, Victoria C Lupson, Emmanuel A Stamatakis, Guy B Williams, William T Clarke, Lin Qiu, Martyn Ezra, Rory McDonald, Stuart Clare, Mark Cassar, Stefan Neubauer, Karen D Ersche, Edward T Bullmore, David K Menon, Kyle Pattinson, James B Row. Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations. Brain : a journal of neurology. 2024-10-07. PMID:39375207. |
in covid-19 survivors, the mr susceptibility increased in the medulla, pons and midbrain regions of the brainstem. |
2024-10-07 |
2024-10-10 |
Not clear |
| Shaogen Zhong, Xindi Lin, Mengxing Wang, Yi Mao, Jiayao Shen, Xiaoxia Du, Lichi Zhang, Jun M. Periaqueductal gray subregions connectivity and its association with micturition desire-awakening function. European child & adolescent psychiatry. 2024-09-05. PMID:39235463. |
our study investigated the correlation between the gradations of micturition desire-awakening (mda) functionality and the functional connectivity of the midbrain periaqueductal gray (pag), a pivotal brainstem hub implicated in the neural regulation of micturition in humans. neuroimaging and behavioral data from 133 patients with pne and 40 healthy children were acquired from functional magnetic resonance imaging (fmri) and precise clinical observations, respectively. |
2024-09-05 |
2024-09-08 |
Not clear |
| Chao Zhang, R Michael Burge. Cholinergic modulation in the vertebrate auditory pathway. Frontiers in cellular neuroscience. vol 18. 2024-07-04. PMID:38962512. |
in this review, we highlight what is known about cholinergic function throughout the auditory system from the ear to the cortex, but with a particular emphasis on brainstem and midbrain auditory centers. |
2024-07-04 |
2024-07-10 |
Not clear |
| Pei Liu, Xuemei Lin, Songdi W. Case report: Overlap syndrome of neuromyelitis optica spectrum disorder with anti-Argonaute antibodies. Frontiers in immunology. vol 15. 2024-06-18. PMID:38887290. |
brain-cervical-thoracic magnetic resonance imaging (mri) showed t2 hyperintensities in the dorsal brainstem and around the midbrain aqueduct and longitudinally transverse myelitis with homogeneous enhancement on gadolinium-enhanced mri. |
2024-06-18 |
2024-06-21 |
Not clear |
| Richard Veale, Mayu Takahash. Pathways for Naturalistic Looking Behavior in Primate II. Superior Colliculus Integrates Parallel Top-down and Bottom-up Inputs. Neuroscience. 2024-03-14. PMID:38484836. |
volitional signals for gaze control are provided by multiple parallel pathways converging on the midbrain superior colliculus (sc), whose deeper layers output to the brainstem gaze circuits. |
2024-03-14 |
2024-03-17 |
Not clear |
| Lingchao Li, Bin Ji, Min Zhao, Lin Bai, Bin Che. Nonfluent Variant Primary Progressive Aphasia on FDG, 11C-PIB, and 18F-APN-1607 PET Imaging. Clinical nuclear medicine. 2023-09-27. PMID:37756439. |
the 11c-pib pet showed no amyloid accumulation; the 18f-fdg pet showed hypometabolism in the bilateral frontal lobe, temporal lobe, and midbrain; and the 18f-apn-1607 pet showed tau accumulation in the brainstem, basal ganglia, and left inferior frontal gyrus. |
2023-09-27 |
2023-10-07 |
Not clear |
| Elisa Aust, Sven-Thomas Graupner, René Günther, Katharina Linse, Markus Joos, Julian Grosskreutz, Johannes Prudlo, Sebastian Pannasch, Andreas Herman. Impairment of oculomotor functions in patients with early to advanced amyotrophic lateral sclerosis. Journal of neurology. 2023-09-15. PMID:37713127. |
it includes impairments of reflexive eye movements to loss of executive inhibitory control, indicating a progressing pathological involvement of prefrontal, midbrain and brainstem areas. |
2023-09-15 |
2023-10-07 |
human |
| Véronique Coizet, Racha Al Tannir, Arnaud Pautrat, Paul G Overto. Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures. Current neuropharmacology. 2023-08-18. PMID:37594168. |
in this review, we describe how brainstem structures also project to the main input structures of the basal ganglia, namely the striatum, the subthalamic nucleus and midbrain dopaminergic neurons, in the context of approach and avoidance (including escape from threat), two fundamental, mutually exclusive behavioral choices in an animal's repertoire in which the brainstem is strongly involved. |
2023-08-18 |
2023-09-07 |
Not clear |
| Elizabeth G Ellis, Juho Joutsa, Jordan Morrison-Ham, Ellen F P Younger, Jacqueline B Saward, Karen Caeyenberghs, Daniel T Cor. Large-scale activation likelihood estimation meta-analysis of parkinsonian disorders. Brain communications. vol 5. issue 3. 2023-06-16. PMID:37324240. |
results in progressive supranuclear palsy and multiple system atrophy aligned with current imaging markers for diagnosis, encompassing the midbrain, and brainstem and putamen, respectively. |
2023-06-16 |
2023-08-14 |
Not clear |
| Rüdiger Land, Andrej Kra. Stability of complex sound representations in the auditory midbrain across the lifespan despite age-related brainstem delays. Hearing research. vol 433. 2023-04-27. PMID:37104991. |
stability of complex sound representations in the auditory midbrain across the lifespan despite age-related brainstem delays. |
2023-04-27 |
2023-08-14 |
mouse |
| Rüdiger Land, Andrej Kra. Stability of complex sound representations in the auditory midbrain across the lifespan despite age-related brainstem delays. Hearing research. vol 433. 2023-04-27. PMID:37104991. |
here we tested how potential age-related changes in the auditory brainstem affect the stability of spatiotemporal multiunit complex speech-like sound representations in the auditory midbrain of old normal hearing cba/j mice. |
2023-04-27 |
2023-08-14 |
mouse |
| Rüdiger Land, Andrej Kra. Stability of complex sound representations in the auditory midbrain across the lifespan despite age-related brainstem delays. Hearing research. vol 433. 2023-04-27. PMID:37104991. |
this shows that although small age-related neural effects in simple sound parameters in the lower brainstem may be present in aging they do not effectively deteriorate complex neural population representations at the level of the auditory midbrain when peripheral hearing remains normal. |
2023-04-27 |
2023-08-14 |
mouse |
| Shintaro Aoyama, Hiroto Okuda, Natsu Furuzawa, Hirokage Yoneda, Daisuke Fujikane, Kentaro Takai, Ayumi Kuramitsu, Yukimasa Muto, Shunsuke Sugiyama, Toshiki Shioiri, Kazutaka Oh. Sex differences in brainstem structure volumes in patients with schizophrenia. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-03-19. PMID:36934103. |
patients with schizophrenia (sz) display moderate reductions in brainstem volumes, including the midbrain, pons, superior cerebellar peduncle, and medulla oblongata. |
2023-03-19 |
2023-08-14 |
Not clear |
| Michael P Trevarrow, S Shekar Dukkipati, Sarah E Baker, Tony W Wilson, Max J Kur. Reduced Brainstem Volume is Associated with Mobility Impairments in Youth with Cerebral Palsy. Research square. 2023-02-24. PMID:36824764. |
we assessed the volume of the pons, midbrain, medulla, and superior cerebellar peduncle (scp) in a cohort of persons with cp (n = 26; age = 16.3 ± 1.0 yrs; gmfcs levels i-iv, females = 12) and a cohort of neurotypical (nt) controls (n = 38; age = 14.3 ± 0.4 yrs, females = 14) using structural mr imaging of the brainstem. |
2023-02-24 |
2023-08-14 |
Not clear |
| Matthew A Weber, Gemma de Choisy, Ramasamy Thangavel, Mackenzie M Conlon, Hisham A Abdelmotilib, Oday Halhouli, Qiang Zhang, Joel C Geerling, Nandakumar S Narayanan, Georgina M Aldridg. Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily impact cortical and subcortical structures and lead to restricted behavioral impacts. bioRxiv : the preprint server for biology. 2023-02-13. PMID:36778400. |
we report that pfc pffs: 1) induced α-syn deposition in multiple cortical and subcortical regions with sparse aggregation in midbrain and brainstem nuclei; 2) did not affect interval timing or working memory but did mildly alter behavioral flexibility as measured by reversal learning; 3) increased open field exploration; and 4) did not affect susceptibility to model of cortical-dominant pathology adds to our understanding of the etiology of varied symptoms in pdd and lbd. |
2023-02-13 |
2023-08-14 |
mouse |