| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammed Zacky Ariffin, Si Yun Ng, Hamzah Nadia, Darrel Koh, Natasha Loh, Naomi Michiko, Sanjay Khann. Neurokinin1 - cholinergic receptor mechanisms in the medial Septum-Dorsal hippocampus axis mediates experimental neuropathic pain. Neurobiology of pain (Cambridge, Mass.). vol 16. 2024-09-03. PMID:39224764. |
the neurokinin-1 receptors (nk1rs) in the forebrain medial septum (ms) region are localized exclusively on cholinergic neurons that partly project to the hippocampus and the cingulate cortex (cg), regions implicated in nociception. |
2024-09-03 |
2024-09-05 |
rat |
| Nima Salimi-Nezhad, Stephan Missault, Anaïs Notario Reinoso, Atefe Hassani, Mahmood Amiri, Georgios A Keliri. The impact of selective and non-selective medial septum stimulation on hippocampal neuronal oscillations: A study based on modeling and experiments. Neurobiology of disease. 2023-02-23. PMID:36822547. |
the medial septum (ms) in the forebrain provides major cholinergic input to the hpc and has been shown to play a significant role in generating oscillations in hippocampal neurons. |
2023-02-23 |
2023-08-14 |
rat |
| Xinyan Li, Hongyan Yu, Bing Zhang, Lanfang Li, Wenting Chen, Quntao Yu, Xian Huang, Xiao Ke, Yunyun Wang, Wei Jing, Huiyun Du, Hao Li, Tongmei Zhang, Liang Liu, Ling-Qiang Zhu, Youming L. Molecularly defined and functionally distinct cholinergic subnetworks. Neuron. 2022-09-21. PMID:36130594. |
cholinergic neurons in the medial septum (ms) constitute a major source of cholinergic input to the forebrain and modulate diverse functions, including sensory processing, memory, and attention. |
2022-09-21 |
2023-08-14 |
Not clear |
| Timothy T. Soncrant, Harold W. Holloway, Barry Horwitz, Stanley I. Rapoport, Yvon A. Lamou. Effect of Nucleus Basalis Magnocellularis Ablation on Local Brain Glucose Utilization in the Rat: Functional Brain Reorganization. The European journal of neuroscience. vol 4. issue 7. 2019-11-20. PMID:12106329. |
most correlations between cholinergic nuclei of both left and right forebrain (medial septum and diagonal band) and right (66/72, mean increase 0.44) but not left (39/72) frontoparietal cortical regions were larger (p < 0.001) in lesioned rats, as were those between most frontoparietal region pairs (516/630, p < 0.001). |
2019-11-20 |
2023-08-12 |
rat |
| Seok Ting Ang, Mohammed Zacky Ariffin, Sanjay Khann. The forebrain medial septal region and nociception. Neurobiology of learning and memory. vol 138. 2018-02-22. PMID:27444843. |
the review also weighs the effects of the medial septum on nociception vis-à-vis the known roles of the region and emphasizes the fact that the region is a part of network of forebrain structures which have been long associated with reward, cognition and affect-motivation and are now implicated in persistent/long-lasting nociception. |
2018-02-22 |
2023-08-13 |
Not clear |
| Seok Ting Ang, Mohammed Zacky Ariffin, Sanjay Khann. The forebrain medial septal region and nociception. Neurobiology of learning and memory. vol 138. 2018-02-22. PMID:27444843. |
the forebrain medial septum, which is an integral part of the septo-hippocampal network, is implicated in sensorimotor integration, fear and anxiety, and spatial learning and memory. |
2018-02-22 |
2023-08-13 |
Not clear |
| F Wang, H Chen, X J Sun, Z J K. Improvement of cognitive deficits in SAMP8 mice by 3-n-butylphthalide. Neurological research. vol 36. issue 3. 2014-09-25. PMID:24512016. |
moreover, the loss of choline acetyltransferase (chat)-positive neurons in the medial septal nucleus and the vertical limb of the diagonal band in samp8 mice was slowed down, as was the decline in the protein and mrna expression of chat in the hippocampus, cerebral cortex, and forebrain. |
2014-09-25 |
2023-08-12 |
mouse |
| Mohammed Zacky Ariffin, Lai Seong Chang, Han Chow Koh, Chian-Ming Low, Sanjay Khann. An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain research. vol 1513. 2013-12-16. PMID:23562704. |
we have now examined the effect of destruction of the cholinergic neurons with microinjection of the immunotoxin 192 igg-saporin into the medial septum on the induction of c-fos protein, an index of neuronal synaptic excitation, in the two forebrain areas to varied episodic experiences. |
2013-12-16 |
2023-08-12 |
rat |
| S Schäble, J P Huston, M L Brandao, E Dere, M A de Souza Silv. Neurokinin-2 receptor antagonism in medial septum influences temporal-order memory for objects and forebrain cholinergic activity. Peptides. vol 31. issue 1. 2010-04-22. PMID:19854231. |
neurokinin-2 receptor antagonism in medial septum influences temporal-order memory for objects and forebrain cholinergic activity. |
2010-04-22 |
2023-08-12 |
rat |
| Nobuaki Matsui, Kazuki Takahashi, Miho Takeichi, Touma Kuroshita, Kaori Noguchi, Kana Yamazaki, Hideaki Tagashira, Kenichi Tsutsui, Hideki Okada, Yuki Kido, Yumiko Yasui, Nobuyuki Fukuishi, Yoshiyasu Fukuyama, Masaaki Akag. Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice. Brain research. vol 1305. 2010-01-05. PMID:19815000. |
cholinergic neuron densities in the medial septum and vertical limb of the diagonal band of the forebrain were evaluated by an immunohistochemical analysis of choline acetyltransferase (chat). |
2010-01-05 |
2023-08-12 |
mouse |
| Kunio Kitamura, Yukiko Itou, Masako Yanazawa, Maki Ohsawa, Rika Suzuki-Migishima, Yuko Umeki, Hirohiko Hohjoh, Yuchio Yanagawa, Toshikazu Shinba, Masayuki Itoh, Kenji Nakamura, Yu-ichi Got. Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice. Human molecular genetics. vol 18. issue 19. 2009-11-09. PMID:19605412. |
both types of mutant mice exhibited the mutation-specific lesser presence of gabaergic and cholinergic neurons in the striatum, medial septum and ventral forebrain nuclei when compared with wild-type mice. |
2009-11-09 |
2023-08-12 |
mouse |
| S Ma, P Bonaventure, T Ferraro, P-J Shen, T C D Burazin, R A D Bathgate, C Liu, G W Tregear, S W Sutton, A L Gundlac. Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat. Neuroscience. vol 144. issue 1. 2007-03-15. PMID:17071007. |
regions that contained highest densities of rlx3-positive fibers included the medial septum, lateral preoptic area, lateral hypothalamus/medial forebrain bundle and ventral hippocampus; and additional fibers were observed in olfactory bulb and olfactory and frontal/cingulate cortices, bed nucleus of the stria terminalis, dorsal endopiriform, intergeniculate, and supramammillary nuclei, and the periaqueductal gray and dorsal raphe. |
2007-03-15 |
2023-08-12 |
mouse |
| Yangu Zhao, Oscar Marín, Edit Hermesz, Aaron Powell, Nuria Flames, Miklós Palkovits, John L R Rubenstein, Heiner Westpha. The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 15. 2003-09-02. PMID:12855770. |
in addition, the number of cholinergic neurons is reduced in several other areas of the subcortical forebrain in lhx8 mutants, including the caudate-putamen, medial septal nucleus, nucleus of the diagonal band, and magnocellular preoptic nucleus. |
2003-09-02 |
2023-08-12 |
mouse |
| Thomas Naumann, Elisabeth Casademunt, Ewald Hollerbach, Jutta Hofmann, Georg Dechant, Michael Frotscher, Yves-Alain Bard. Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923404. |
the incomplete nature of the p75ntr mutation used previously, coupled with difficulties in delineating the mouse medial septum and the impact of the genetic background on cell numbers, all contribute to explain previous difficulties in establishing the role of p75ntr in regulating cholinergic neuron numbers in the mouse forebrain. |
2002-04-08 |
2023-08-12 |
mouse |
| D G Xu, R G Korneluk, K Tamai, N Wigle, A Hakim, A Mackenzie, G S Robertso. Distribution of neuronal apoptosis inhibitory protein-like immunoreactivity in the rat central nervous system. The Journal of comparative neurology. vol 382. issue 2. 1997-07-21. PMID:9183692. |
in the forebrain, immunoreactive neurons were detected in the cortex, the hippocampus (pyramidal cells, dentate granule cells, and interneurons), the striatum (cholinergic interneurons), the basal forebrain (ventral pallidum, medial septal nucleus, and diagonal band), the thalamus (lateral and ventral nuclei), the habenula, the globus pallidus, and the entopenduncular nucleus. |
1997-07-21 |
2023-08-12 |
rat |
| N Tsuji, K Tsujimoto, N Takada, K Ozaki, M Ohta, N Ito. Expression of insulin receptor-related receptor in the rat brain examined by in situ hybridization and immunohistochemistry. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883958. |
the expression of irr mrna in the brain was highly restricted to the forebrain including the nucleus of the diagonal band, medial septal nucleus, ventral pallidum, accumbens nucleus and caudate putamen, and the brainstem including the prepositus hypoglossal nucleus, medial vestibular nucleus, gigantocell reticular nucleus, paragigantocellular nucleus and ventral cochlear nucleus. |
1997-02-20 |
2023-08-12 |
rat |
| K Sugaya, M McKinne. Nitric oxide synthase gene expression in cholinergic neurons in the rat brain examined by combined immunocytochemistry and in situ hybridization histochemistry. Brain research. Molecular brain research. vol 23. issue 1-2. 1994-08-08. PMID:7518028. |
in the forebrain, chat-immunoreactive cells or cell groups were observed in medial septum (ms), vertical limbs of diagonal band (dbv) and horizontal limbs of diagonal band (dbh), nucleus basalis magnocellularis (nbm), substantia innominata (si), and striatum (st). |
1994-08-08 |
2023-08-12 |
rat |
| R Schneggenburger, F Tempia, A Konnert. Glutamate- and AMPA-mediated calcium influx through glutamate receptor channels in medial septal neurons. Neuropharmacology. vol 32. issue 11. 1994-03-21. PMID:7509048. |
the ca(2+)-fraction of the ion current flowing through glutamate receptor channels activated either by glutamate or by ampa was determined in forebrain neurons of the rat medial septum. |
1994-03-21 |
2023-08-12 |
rat |
| R Schneggenburger, Z Zhou, A Konnerth, E Nehe. Fractional contribution of calcium to the cation current through glutamate receptor channels. Neuron. vol 11. issue 1. 1993-09-02. PMID:7687849. |
the ca2+ fraction of the ion current flowing through glutamatergic nmda and ampa/kainate receptor channels was determined in forebrain neurons of the medial septum. |
1993-09-02 |
2023-08-12 |
Not clear |
| J C Lauterborn, P J Isackson, R Montalvo, C M Gal. In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord. Brain research. Molecular brain research. vol 17. issue 1-2. 1993-03-16. PMID:8381910. |
in forebrain, hybridization of a 35s-labeled rat chat crna densely labeled neurons in the well-characterized basal forebrain cholinergic system including the medial septal nucleus, diagonal bands of broca, nucleus basalis of meynert and substantia innominata, as well as in the striatum, ventral pallidum, and olfactory tubercle. |
1993-03-16 |
2023-08-12 |
rat |