All Relations between hypothalamus and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. while oxtr expression levels in the prefrontal cortex did not vary according to the body weight and oxytocin application, oxtr levels in the hypothalamus were higher in the hfd- and/or oxytocin-treated animals. 2024-03-31 2024-04-03 rat
Jorge Miguel Amaya, Hetty C M Sips, Eva M G Viho, Jan Kroon, Onno C Meije. Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain. Frontiers in endocrinology. vol 14. 2024-02-02. PMID:38303978. after chronic treatment with corticosterone, dihydrotestosterone, a combination of both, and corticosterone in combination with the ar antagonist enzalutamide, we compared the expression of glucocorticoid receptor (nr3c1, also abbreviated gr) target genes in brain regions where ar and gr are co-expressed, namely: prefrontal cortex, hypothalamus, hippocampus, ventral tegmental area and substantia nigra. 2024-02-02 2024-02-04 mouse
Gonçalo M Melo, Adriana M Capucho, Joana F Sacramento, José Ponce-de-Leão, Marcos V Fernandes, Inês F Almeida, Fátima O Martins, Silvia V Cond. Overnutrition during Pregnancy and Lactation Induces Gender-Dependent Dysmetabolism in the Offspring Accompanied by Heightened Stress and Anxiety. Nutrients. vol 16. issue 1. 2024-01-11. PMID:38201896. the offspring were analyzed at postnatal days 21 and 28 and at 2 months old (pd21, pd28, and pd60) for their metabolic profiles (weight, fasting glycemia insulin sensitivity, and glucose tolerance) and euthanized for brain collection to evaluate metabolism and inflammation in the hypothalamus, hippocampus, and prefrontal cortex using western blot markers of synaptic dynamics. 2024-01-11 2024-01-13 rat
Romain Icick, Alexey Shadrin, Børge Holen, Naz Karadag, Nadine Parker, Kevin O'Connell, Oleksandr Frei, Shahram Bahrami, Margrethe Høegh, Trine Lagerberg, Weiqiu Cheng, Tyler Seibert, Srdjan Djurovic, Anders Dale, Hang Zhou, Howard Edenberg, Joel Gelernter, Olav Smeland, Guy Hindley, Ole Andreasse. Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals. Research square. 2024-01-10. PMID:38196616. loci were mapped to genes enriched for brain regions relevant for aud (striatum, hypothalamus, and prefrontal cortex) and potential drug targets (gabaergic, dopaminergic and serotonergic neurons). 2024-01-10 2024-01-13 Not clear
Agnes Hazi, Esmaeil Ebrahimie, Elizabeth A Levay, Manijeh Mohammadi-Dehcheshmeh, Matt Zelko, Antonina Govic, Helen Nasse. Crosstalk between short- and long-term calorie restriction transcriptomic signatures with anxiety-like behavior, aging, and neurodegeneration: implications for drug repurposing. Frontiers in behavioral neuroscience. vol 17. 2023-12-14. PMID:38094940. we investigated the effects of short- and long-term cr on behavior as well as transcriptome profiles in the hypothalamus, amygdala, prefrontal cortex, pituitary, and adrenal glands of hooded wistar and long evans male rats. 2023-12-14 2023-12-17 rat
Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). 2023-10-13 2023-10-15 human
Zubeyde Ercan, Ozgur Bulmus, Emine Kacar, Ihsan Serhatlioglu, Gokhan Zorlu, Haluk Kelestimu. Treadmill Exercise Improves Behavioral and Neurobiological Alterations in Restraint-Stressed Rats. Journal of molecular neuroscience : MN. 2023-10-04. PMID:37794307. brain-derived neurotrophic factor (bdnf), dopamine receptors, and serotonin receptor (htr2a) gene expression in the prefrontal cortex, corpus striatum, and hypothalamus were decreased by crs. 2023-10-04 2023-10-07 rat
Raoni Conceição Dos-Santos, Brook L W Sweeten, Claire E Stelly, Jeffrey G Taske. The Neuroendocrine Impact of Acute Stress on Synaptic Plasticity. Endocrinology. 2023-10-03. PMID:37788632. we describe the synaptic plasticity that occurs in four stress-associated brain structures, the hypothalamus, hippocampus, amygdala, and prefrontal cortex, in response to single or short-term stress exposure. 2023-10-03 2023-10-07 Not clear
Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. this, study, then, was designed to analyze the long-term effects of early postnatal exposure to cmi on the expression of 5-ht1a, 5-ht2a, and 5-ht3 receptors, as well as bdnf and gr in the following brain regions: pfc, amygdala, hippocampus, and hypothalamus, which could be related to alterations in memory and learning, as evaluated using the novel object recognition (nor) and morris water maze (mwm). 2023-09-15 2023-10-07 rat
Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. expression of the 5-ht1a receptor increased in the hippocampus, amygdala, and hypothalamus, but decreased in the pfc, while the 5-ht2a and bdnf receptors decreased their expression in the pfc, amygdala, and hippocampus. 2023-09-15 2023-10-07 rat
Andreia Amaro, Diana Sousa, Mariana Sá-Rocha, Marcos Divino Ferreira-Junior, Daniela Rosendo-Silva, Lucas Paulo Jacinto Saavedra, Cátia Barra, Tamaeh Monteiro-Alfredo, Rodrigo Mello Gomes, Paulo Cezar de Freitas Mathias, Filipa I Baptista, Paulo Matafom. Postnatal Overfeeding in Rodents Induces a Neurodevelopment Delay and Anxious-like Behaviour Accompanied by Sex- and Brain-Region-Specific Synaptic and Metabolic Changes. Nutrients. vol 15. issue 16. 2023-08-26. PMID:37630771. neurodevelopmental tests were conducted at infancy, whereas behavioural tests to assess locomotion, anxiety, and memory were performed at adolescence, together with molecular analysis of the hippocampus, hypothalamus, and prefrontal cortex. 2023-08-26 2023-09-07 Not clear
Payman Raise-Abdullahi, Morvarid Meamar, Abbas Ali Vafaei, Maryam Alizadeh, Masoomeh Dadkhah, Sakineh Shafia, Mohadeseh Ghalandari-Shamami, Ramtin Naderian, Seyed Afshin Samaei, Ali Rashidy-Pou. Hypothalamus and Post-Traumatic Stress Disorder: A Review. Brain sciences. vol 13. issue 7. 2023-07-29. PMID:37508942. linked to the prefrontal cortex and limbic structures, especially the amygdala and hippocampus, the hypothalamus acts as a central hub, integrating physiological aspects of the stress response. 2023-07-29 2023-08-14 Not clear
Emine Kacar, Ozgur Bulmus, Zubeyde Ercan, Ilay Buran Kavuran, Gokhan Zorlu, Fatih Tan, Ihsan Serhatlioglu, Haluk Kelestimu. Treadmill exercise has healing effects on obesity-induced sexual behavior disorder through kisspeptin and kiss1R expression in male rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 3. 2023-06-11. PMID:37300694. treadmill exercise caused a significant decrease in ef, ml, il, mf, if, iii, el, pei, ir1, mft, ift, irt sexual behavior parameters and kisspeptin and kiss1r gene expression in the hypothalamus, hippocampus, prefrontal cortex and corpus striatum in e group compared to c group (p<0.05), and a significant increase in ml, il, iii, el sexual behavior parameters (p<0.05). 2023-06-11 2023-08-14 rat
Emine Kacar, Ozgur Bulmus, Zubeyde Ercan, Ilay Buran Kavuran, Gokhan Zorlu, Fatih Tan, Ihsan Serhatlioglu, Haluk Kelestimu. Treadmill exercise has healing effects on obesity-induced sexual behavior disorder through kisspeptin and kiss1R expression in male rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 3. 2023-06-11. PMID:37300694. based on this effect, we believe that it is caused by an increase in kisspeptin and kiss1r expression in the hypothalamus, hippocampus, prefrontal cortex and corpus striatum. 2023-06-11 2023-08-14 rat
Zala Slabe, Rawien A Balesar, Ronald W H Verwer, Joop J Van Heerikhuize, Gwyneth A Pechler, Maja Zorović, Witte J G Hoogendijk, Dick F Swaa. Alterations in pituitary adenylate cyclase-activating polypeptide in major depressive disorder, bipolar disorder, and comorbid depression in Alzheimer's disease in the human hypothalamus and prefrontal cortex. Psychological medicine. 2023-05-25. PMID:37226771. alterations in pituitary adenylate cyclase-activating polypeptide in major depressive disorder, bipolar disorder, and comorbid depression in alzheimer's disease in the human hypothalamus and prefrontal cortex. 2023-05-25 2023-08-14 human
Yaling Liu, Anna Li, Chloe Bair-Marshall, Helen Xu, Hyun Jung Jee, Elaine Zhu, Mengqi Sun, Qiaosheng Zhang, Arthur Lefevre, Zhe Sage Chen, Valery Grinevich, Robert C Froemke, Jing Wan. Oxytocin promotes prefrontal population activity via the PVN-PFC pathway to regulate pain. Neuron. 2023-04-06. PMID:37023755. here, we examined how oxytocin (ot) signaling from the hypothalamus regulates nociceptive coding in the pfc. 2023-04-06 2023-08-14 rat
Xiaoju Liu, Haijuan Wang, Xiaoyu Wang, Yinxia Ning, Wei Liu, Jie Ga. Baixiangdan capsule and Shuyu capsule regulate anger-out and anger-in, respectively: GB1-mediated GABA can regulate 5-HT levels in multiple brain regions. Aging. vol 15. 2023-03-29. PMID:36988497. the improvement way is as follows: decreased abnormal increase of gaba and gb1 in the drn further mediated synaptic inhibition and increased 5-ht level in the drn, leading to increased 5-ht levels in the pfc, hypothalamus, and hippocampus. 2023-03-29 2023-08-14 rat
Yajie Jiang, Manshu Zou, Yeqing Wang, Yuhong Wan. Nucleus Accumbens in the Pathogenesis of Major Depressive Disorder: A Brief Review. Brain research bulletin. 2023-03-08. PMID:36889362. extensive studies have demonstrated the involvement of nuclei such as the prefrontal cortex (pfc), hippocampus (hip), nucleus accumbens (nac), hypothalamus, etc., in mdd. 2023-03-08 2023-08-14 Not clear
Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. we exposed female rats to the aba paradigm and measured the levels of da, 5-ht, and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxyindoleacetic acid (5-hiaa), and dopaminergic type 2 (d2) receptors density in feeding- and reward-implicated brain regions (i.e., cerebral cortex, cx; prefrontal cortex, pfc; caudate putamen, cpu; nucleus accumbens, nacc; amygdala, amy; hypothalamus, hyp; hippocampus, hipp). 2023-03-02 2023-08-14 rat
M Maetzi Estévez-Cabrera, Fausto Sánchez-Muñoz, Gilberto Pérez-Sánchez, Lenin Pavón, Adrian Hernández-Díazcouder, J Luis Córtes Altamirano, C Soria-Fregoso, Alfonso Alfaro-Rodríguez, Herlinda Bonilla-Jaim. Therapeutic treatment with fluoxetine using the chronic unpredictable stress model induces changes in neurotransmitters and circulating miRNAs in extracellular vesicles. Heliyon. vol 9. issue 2. 2023-02-28. PMID:36852042. after cums, the rats performed the fst, and serum levels of cort and six micrornas (mir-16, -21, -144, -155, -146a, -223) were analyzed, as were levels of dopamine, noradrenaline, and serotonin in the prefrontal cortex, hippocampus, and hypothalamus. 2023-02-28 2023-08-14 rat