| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Mota-Rojas, Alexandra L Whittaker, Cécile Bienboire-Frosini, Jhon Buenhombre, Patricia Mora-Medina, Adriana Domínguez-Oliva, Julio Martínez-Burnes, Ismael Hernández-Avalos, Adriana Olmos-Hernández, Antonio Verduzco-Mendoza, Alejandro Casas-Alvarado, Karina Lezama-García, Temple Grandi. The neurobiological basis of emotions and their connection to facial expressions in non-human mammals: insights in nonverbal communication. Frontiers in veterinary science. vol 12. 2025-03-24. PMID:40125317. |
from a neurophysiological perspective, emotions are processed in several brain structures, mainly from the limbic system, such as the hypothalamus, hypophysis, hippocampus, prefrontal cortex, and amygdala. |
2025-03-24 |
2025-03-26 |
Not clear |
| Daniel Mota-Rojas, Alexandra L Whittaker, Genaro A Coria-Avila, Julio Martínez-Burnes, Patricia Mora-Medina, Adriana Domínguez-Oliva, Ismael Hernández-Avalos, Adriana Olmos-Hernández, Antonio Verduzco-Mendoza, Alejandro Casas-Alvarado, Temple Grandi. How facial expressions reveal acute pain in domestic animals with facial pain scales as a diagnostic tool. Frontiers in veterinary science. vol 12. 2025-03-19. PMID:40104548. |
the possibility of using facial expression as an indicator of pain is due to the direct relationship between the activation of different regions of the central nervous system such as the somatosensory cortex, prefrontal cortex, amygdala, hippocampus, and hypothalamus, and their connections with the motor cortex to elicit motor responses including the movement of facial muscles. |
2025-03-19 |
2025-03-21 |
mouse |
| Jinxing Li, Yimei Wang, Simou Wu, Zhimo Zhou, Wen Jia, Xi Shen, Yun Li, Fang He, Ruyue Chen. Postbiotics Made From Selected Lactic Acid Bacteria Improves Chronic Restraint Stress-Induced Anhedonia and Sleep Disorders. Molecular nutrition & food research. 2025-03-06. PMID:40045653. |
additionally, postbiotics administration significantly increased glutamate and gaba levels in both the prefrontal cortex and hypothalamus, as well as gaba levels in the feces. |
2025-03-06 |
2025-03-08 |
mouse |
| Yunjie Li, Heli Li, Cong Hu, Jinru Cui, Feiyan Zhang, Jinzhu Zhao, Yangyang Feng, Chen Hu, Liping Yang, Hong Qian, Jingxue Pan, Xiaoping Luo, Zhouping Tang, Yan Ha. The role of the dopamine system in autism spectrum disorder revealed using machine learning: an ABIDE database-based study. Cerebral cortex (New York, N.Y. : 1991). vol 35. issue 2. 2025-03-04. PMID:40036245. |
functional connectivity was significantly higher in autism spectrum disorder children between the ventral tegmental area and substantia nigra, prefrontal cortex, nucleus accumbens, and between the substantia nigra and hypothalamus compared to typically developing children. |
2025-03-04 |
2025-03-07 |
Not clear |
| Gaoyuan Lu, Fengfei Ma, Pingli Wei, Min Ma, Vu Ngoc Huong Tran, Brian A Baldo, Lingjun L. Cocaine-Induced Remodeling of the Rat Brain Peptidome: Quantitative Mass Spectrometry Reveals Anatomically Specific Patterns of Cocaine-Regulated Peptide Changes. ACS chemical neuroscience. vol 16. issue 2. 2025-01-15. PMID:39810605. |
label-free peptidomic analysis using liquid chromatography coupled with tandem ms (lc-ms/ms) was used to describe the dynamic changes of endogenous peptides in five brain regions (nucleus accumbens, dorsal striatum, prefrontal cortex, amygdala, and hypothalamus) following an acute systemic cocaine challenge. |
2025-01-15 |
2025-01-17 |
rat |
| Fernanda da Silva Rodrigues, Jeferson Jantsch, Gabriel de Farias Fraga, Victor Silva Dias, Camila Pereira Medeiros, Fernanda Wickert, Nadja Schroder, Marcia Giovernardi, Renata Padilha Guede. Cannabidiol partially rescues behavioral, neuroinflammatory and endocannabinoid dysfunctions stemming from maternal obesity in the adult offspring. Neuropharmacology. vol 262. 2024-10-25. PMID:39447736. |
behavioral tests assessed anxiety-like manifestations and social behavior, while neuroinflammatory and endocannabinoid markers were evaluated in the hypothalamus, prefrontal cortex (pfc) and hippocampus, as well as the biochemical profile in the plasma. |
2024-10-25 |
2024-10-28 |
rat |
| Fernanda da Silva Rodrigues, Jeferson Jantsch, Gabriel de Farias Fraga, Victor Silva Dias, Camila Pereira Medeiros, Fernanda Wickert, Nadja Schroder, Marcia Giovernardi, Renata Padilha Guede. Cannabidiol partially rescues behavioral, neuroinflammatory and endocannabinoid dysfunctions stemming from maternal obesity in the adult offspring. Neuropharmacology. vol 262. 2024-10-25. PMID:39447736. |
cbd treatment attenuated maternal obesity-induced anxiety-like and social behavioral alterations, restoring exacerbated astrocytic and microglial markers in the hypothalamus, pfc and hippocampus of the offspring, as well as endocannabinoid levels in the pfc, with notable sex differences. |
2024-10-25 |
2024-10-28 |
rat |
| Aldo R Tejeda-Martínez, Ana R Ramos-Molina, Patricia A Brand-Rubalcava, Mario E Flores-Sot. Involvement of serotonergic receptors in depressive processes and their modulation by β-arrestins: A review. Medicine. vol 103. issue 28. 2024-07-12. PMID:38996114. |
disorders such as anxiety, depression, schizophrenia, epilepsy, sexual disorders, and eating disorders, have been closely linked to variations in 5-ht concentrations and modifications in brain structures, including the raphe nuclei (rn), prefrontal cortex, basal ganglia, hippocampus, and hypothalamus, among others. |
2024-07-12 |
2024-07-15 |
Not clear |
| Kristoffer Højgaard, Erik Kaadt, Birgitte Hviid Mumm, Vitor Silva Pereira, Betina Elfvin. Dysregulation of circadian clock gene expression patterns in a treatment-resistant animal model of depression. Journal of neurochemistry. 2024-07-06. PMID:38970299. |
in the hippocampus, 10 ccgs were affected by acth treatment, whereas in the adrenal glands, 5 ccgs were affected and in the prefrontal cortex, hypothalamus and liver 4 ccgs were regulated. |
2024-07-06 |
2024-07-12 |
rat |
| Christina Thomou, Markus Nussbaumer, Eleni Grammenou, Chrysoula Komini, Angeliki-Maria Vlaikou, Maria P Papageorgiou, Michaela D Filio. Early Handling Exerts Anxiolytic Effects and Alters Brain Mitochondrial Dynamics in Adult High Anxiety Mice. Molecular neurobiology. 2024-05-18. PMID:38761326. |
we also investigated eh-induced effects at the protein and mrna levels in adult male hab mice in the hypothalamus, the prefrontal cortex, and the hippocampus by examining the same mitochondrial/energy pathways and mitochondrial dynamics mechanisms (fission, fusion, biogenesis, and mitophagy) in all three brain regions.eh exerts anxiolytic effects in adult hab but not nab male mice and does not affect hab or nab maternal behavior, although basal hab vs. nab maternal behaviors differ. |
2024-05-18 |
2024-05-27 |
mouse |
| Yehong Fang, Yunkai Sun, Yi Liu, Tieqiao Liu, Wei Hao, Yanhui Lia. Neurobiological mechanisms and related clinical treatment of addiction: a review. Psychoradiology. vol 2. issue 4. 2024-04-26. PMID:38665277. |
the changes in the orbitofrontal cortex, dorsolateral prefrontal cortex, amygdala, and hypothalamus emotional system in the withdrawal/negative affect stage involve increases in negative emotional states, dysphoric-like effects, and stress-like responses. |
2024-04-26 |
2024-04-28 |
Not clear |
| Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. |
while oxtr expression levels in the prefrontal cortex did not vary according to the body weight and oxytocin application, oxtr levels in the hypothalamus were higher in the hfd- and/or oxytocin-treated animals. |
2024-03-31 |
2024-04-03 |
rat |
| Jorge Miguel Amaya, Hetty C M Sips, Eva M G Viho, Jan Kroon, Onno C Meije. Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain. Frontiers in endocrinology. vol 14. 2024-02-02. PMID:38303978. |
after chronic treatment with corticosterone, dihydrotestosterone, a combination of both, and corticosterone in combination with the ar antagonist enzalutamide, we compared the expression of glucocorticoid receptor (nr3c1, also abbreviated gr) target genes in brain regions where ar and gr are co-expressed, namely: prefrontal cortex, hypothalamus, hippocampus, ventral tegmental area and substantia nigra. |
2024-02-02 |
2024-02-04 |
mouse |
| Gonçalo M Melo, Adriana M Capucho, Joana F Sacramento, José Ponce-de-Leão, Marcos V Fernandes, Inês F Almeida, Fátima O Martins, Silvia V Cond. Overnutrition during Pregnancy and Lactation Induces Gender-Dependent Dysmetabolism in the Offspring Accompanied by Heightened Stress and Anxiety. Nutrients. vol 16. issue 1. 2024-01-11. PMID:38201896. |
the offspring were analyzed at postnatal days 21 and 28 and at 2 months old (pd21, pd28, and pd60) for their metabolic profiles (weight, fasting glycemia insulin sensitivity, and glucose tolerance) and euthanized for brain collection to evaluate metabolism and inflammation in the hypothalamus, hippocampus, and prefrontal cortex using western blot markers of synaptic dynamics. |
2024-01-11 |
2024-01-13 |
rat |
| Romain Icick, Alexey Shadrin, Børge Holen, Naz Karadag, Nadine Parker, Kevin O'Connell, Oleksandr Frei, Shahram Bahrami, Margrethe Høegh, Trine Lagerberg, Weiqiu Cheng, Tyler Seibert, Srdjan Djurovic, Anders Dale, Hang Zhou, Howard Edenberg, Joel Gelernter, Olav Smeland, Guy Hindley, Ole Andreasse. Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals. Research square. 2024-01-10. PMID:38196616. |
loci were mapped to genes enriched for brain regions relevant for aud (striatum, hypothalamus, and prefrontal cortex) and potential drug targets (gabaergic, dopaminergic and serotonergic neurons). |
2024-01-10 |
2024-01-13 |
Not clear |
| Agnes Hazi, Esmaeil Ebrahimie, Elizabeth A Levay, Manijeh Mohammadi-Dehcheshmeh, Matt Zelko, Antonina Govic, Helen Nasse. Crosstalk between short- and long-term calorie restriction transcriptomic signatures with anxiety-like behavior, aging, and neurodegeneration: implications for drug repurposing. Frontiers in behavioral neuroscience. vol 17. 2023-12-14. PMID:38094940. |
we investigated the effects of short- and long-term cr on behavior as well as transcriptome profiles in the hypothalamus, amygdala, prefrontal cortex, pituitary, and adrenal glands of hooded wistar and long evans male rats. |
2023-12-14 |
2023-12-17 |
rat |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |
| Zubeyde Ercan, Ozgur Bulmus, Emine Kacar, Ihsan Serhatlioglu, Gokhan Zorlu, Haluk Kelestimu. Treadmill Exercise Improves Behavioral and Neurobiological Alterations in Restraint-Stressed Rats. Journal of molecular neuroscience : MN. 2023-10-04. PMID:37794307. |
brain-derived neurotrophic factor (bdnf), dopamine receptors, and serotonin receptor (htr2a) gene expression in the prefrontal cortex, corpus striatum, and hypothalamus were decreased by crs. |
2023-10-04 |
2023-10-07 |
rat |
| Raoni Conceição Dos-Santos, Brook L W Sweeten, Claire E Stelly, Jeffrey G Taske. The Neuroendocrine Impact of Acute Stress on Synaptic Plasticity. Endocrinology. 2023-10-03. PMID:37788632. |
we describe the synaptic plasticity that occurs in four stress-associated brain structures, the hypothalamus, hippocampus, amygdala, and prefrontal cortex, in response to single or short-term stress exposure. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
this, study, then, was designed to analyze the long-term effects of early postnatal exposure to cmi on the expression of 5-ht1a, 5-ht2a, and 5-ht3 receptors, as well as bdnf and gr in the following brain regions: pfc, amygdala, hippocampus, and hypothalamus, which could be related to alterations in memory and learning, as evaluated using the novel object recognition (nor) and morris water maze (mwm). |
2023-09-15 |
2023-10-07 |
rat |