Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Hendrik Heinbockel, Gregor Leicht, Anthony D Wagner, Lars Schwab. Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation. eLife. vol 13. 2025-01-29. PMID:39878439. |
while post-retrieval glucocorticoids did not affect subsequent memory, the impairing effect of noradrenergic arousal on final recall depended on hippocampal reactivation and category-level reinstatement in the ventral temporal cortex during memory cueing. |
2025-01-29 |
2025-01-31 |
Not clear |
Karel Kalecký, Luna Buitrago, Juan Marcos Alarcon, Abanish Singh, Teodoro Bottiglieri, Rima Kaddurah-Daouk, Alejandro Iván Hernánde. Rescue of hippocampal synaptic plasticity and memory performance by Fingolimod (FTY720) in APP/PS1 model of Alzheimer's disease is accompanied by correction in metabolism of sphingolipids, polyamines, and phospholipid saturation composition. bioRxiv : the preprint server for biology. 2025-01-27. PMID:39868189. |
synaptic plasticity and memory were rescued, with spermidine synthesis in temporal cortex best corresponding to hippocampal ca3-ca1 plasticity normalization. |
2025-01-27 |
2025-01-29 |
mouse |
Di Xia, Linming Zhang, Rong Mei, Chunhua Wu, Yan Liu, Hongyu Chen, Ling Che. Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy. Synapse (New York, N.Y.). vol 79. issue 1. 2024-12-27. PMID:39729046. |
after creation of epilepsy models with healthy male sprague-dawley rats using lithium and pilocarpine, the expression of mst1 in the temporal cortex and hippocampus was evaluated at different time points (6 h, 24 h, 3 days, 7 days, 14 days, and 30 days after seizures) using immunofluorescence, immunohistochemistry, and western blotting. |
2024-12-27 |
2024-12-29 |
rat |
Di Xia, Linming Zhang, Rong Mei, Chunhua Wu, Yan Liu, Hongyu Chen, Ling Che. Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy. Synapse (New York, N.Y.). vol 79. issue 1. 2024-12-27. PMID:39729046. |
neuronal apoptosis in temporal cortex and hippocampus of epileptic rats was detected using terminal deoxynucleotidyl transferase dutp nick end labeling staining. |
2024-12-27 |
2024-12-29 |
rat |
Di Xia, Linming Zhang, Rong Mei, Chunhua Wu, Yan Liu, Hongyu Chen, Ling Che. Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy. Synapse (New York, N.Y.). vol 79. issue 1. 2024-12-27. PMID:39729046. |
mst1 was expressed in the neuronal membrane and cytoplasm of the temporal cortex and hippocampus. |
2024-12-27 |
2024-12-29 |
rat |
Kaleah Balcomb, Caitlin Johnston, Tomas Kavanagh, Dominique Leitner, Julie Schneider, Glenda Halliday, Thomas Wisniewski, Margaret Sunde, Eleanor Drummon. SMOC1 colocalizes with Alzheimer's disease neuropathology and delays Aβ aggregation. Acta neuropathologica. vol 148. issue 1. 2024-11-25. PMID:39585417. |
the distribution of smoc1 in human brain tissue was assessed in 3 brain regions (temporal cortex, hippocampus, and frontal cortex) using immunohistochemistry in a cohort of 73 cases encompassing advanced ad, mild cognitive impairment (mci), preclinical ad, and cognitively normal controls. |
2024-11-25 |
2024-11-27 |
human |
Kaleah Balcomb, Caitlin Johnston, Tomas Kavanagh, Dominique Leitner, Julie Schneider, Glenda Halliday, Thomas Wisniewski, Margaret Sunde, Eleanor Drummon. SMOC1 colocalizes with Alzheimer's disease neuropathology and delays Aβ aggregation. Research square. 2024-11-22. PMID:39574902. |
the distribution of smoc1 in human brain tissue was assessed in 3 brain regions (temporal cortex, hippocampus, frontal cortex) using immunohistochemistry in a cohort of 73 cases encompassing advanced ad, mild cognitive impairment (mci), preclinical ad and cognitively normal controls. |
2024-11-22 |
2024-11-24 |
human |
Stéphane Jean, Rifeng Jiang, Yihai Dai, Weitao Chen, Weihong Liu, Donghuo Deng, Panashe Tevin Tagu, Xiaoqiang Wei, Shan Chen, Xinrong Fang, Shiwei Son. Optimizing outcomes in drug-resistant mesial temporal lobe epilepsy patients undergoing stereoelectroencephalography-guided radiofrequency thermocoagulation. Therapeutic advances in neurological disorders. vol 17. 2024-10-15. PMID:39403115. |
mesial temporal lobe epilepsy (mtle) epileptiform discharges have been reported to arise from the hippocampus or the extrahippocampal medial temporal cortex, such as the amygdala, and then propagate to the temporal lobe cortex. |
2024-10-15 |
2024-10-17 |
Not clear |
Shiwei Song, Yihai Dai, Yutong Yao, Jie Liu, Dezhong Yao, Yifei Cao, Bingling Lin, Yuetong Zheng, Ruxiang Xu, Yan Cui, Daqing Gu. The high frequency oscillations in the amygdala, hippocampus, and temporal cortex during mesial temporal lobe epilepsy. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104697. |
the high frequency oscillations in the amygdala, hippocampus, and temporal cortex during mesial temporal lobe epilepsy. |
2024-08-06 |
2024-08-08 |
Not clear |
Shiwei Song, Yihai Dai, Yutong Yao, Jie Liu, Dezhong Yao, Yifei Cao, Bingling Lin, Yuetong Zheng, Ruxiang Xu, Yan Cui, Daqing Gu. The high frequency oscillations in the amygdala, hippocampus, and temporal cortex during mesial temporal lobe epilepsy. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104697. |
the mesial temporal lobe epilepsy (mtle) seizures are believed to originate from medial temporal structures, including the amygdala, hippocampus, and temporal cortex. |
2024-08-06 |
2024-08-08 |
Not clear |
Monachesi Bianca, Alice Deruti, Jeroen Vaes, Paolo Leoni, Alessandro Grecucc. How sexual objectification marks the brain: fMRI evidence of self-objectification and its harmful emotional consequences. NeuroImage. 2024-07-11. PMID:38992451. |
the results revealed increased brain activity in objectifying contexts, impacting cortical (frontal, occipital and temporal cortex) and subcortical regions (thalamus, and hippocampus) involved in visual, emotion, and social processing. |
2024-07-11 |
2024-07-14 |
human |
Yuenan Ban, Xiaolan Yang, Dandan Tan, Chen Gong, Yuan Gao, Jinxian Yuan, Yangmei Chen, You Wang, Tao X. Sorbs2 regulates seizure activity by influencing AMPAR-mediated excitatory synaptic transmission in temporal lobe epilepsy. Neurochemistry international. 2024-03-30. PMID:38555055. |
first, we found that the expression of sorbs2 was obviously increased in the hippocampus and cortex of a tle mouse model and in the temporal cortex of tle patients, indicating an abnormal expression pattern of sorbs2 in tle. |
2024-03-30 |
2024-04-02 |
mouse |
Liangbo Kong, Xiaxin Yang, Anqi Sun, Xue Yang, Xiuhe Zhao, Shengjun Wan. Rapamycin alleviates mitochondrial dysfunction in anti-NMDAR encephalitis mice. International immunopharmacology. vol 132. 2024-03-29. PMID:38552295. |
we first uncovered excessive mitochondrial fission in the hippocampus and temporal cortex of anti-nmdar encephalitis mice, indicated by elevated level of phospho-drp1 (ser616) (p-drp1-s616). |
2024-03-29 |
2024-04-01 |
mouse |
Mariana Cairós-González, Emilio Verche, Sergio Hernández, María Ángeles Alons. Cognitive flexibility impairment in temporal lobe epilepsy: The impact of epileptic foci lateralization on executive functions. Epilepsy & behavior : E&B. vol 151. 2023-12-30. PMID:38159506. |
temporal lobe epilepsy (tle) has been associated with memory impairments, which are typically linked to hippocampal and mesial temporal cortex lesions. |
2023-12-30 |
2024-01-05 |
Not clear |
Yaşar Türk, İsmail Devecioğlu, Atakan Küskün, Cem Öge, Elmas Beyazyüz, Yakup Albayra. ROI-based analysis of diffusion indices in healthy subjects and subjects with deficit or non-deficit syndrome schizophrenia. Psychiatry research. Neuroimaging. vol 336. 2023-11-05. PMID:37925764. |
notably, specific rois with reduced fa in schizophrenia patients included bilateral nucleus accumbens, left fusiform area, brain stem, anterior corpus callosum, left rostral and caudal anterior cingulate, right posterior cingulate, left thalamus, left hippocampus, left inferior temporal cortex, right superior temporal cortex, left pars triangularis and right lingual gyrus. |
2023-11-05 |
2023-11-08 |
human |
Valentin Garcia, Marine Blaquiere, Alicia Janvier, Noemie Cresto, Carla Lana, Athenais Genin, Helene Hirbec, Etienne Audinat, Adele Faucherre, Emmanuel L Barbier, Sophie Hamelin, Philippe Kahane, Chris Jopling, Nicola March. PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions. Neurobiology of disease. 2023-09-17. PMID:37717661. |
in brain tissue micro-punches obtained from 18 drug-resistant mtle patients, piezo1 expression positively correlated with that of the pro-inflammatory biomarkers tnfα, il-1β, and nf-kb in the epileptogenic hippocampus compared to the adjacent amygdala and temporal cortex. |
2023-09-17 |
2023-10-07 |
mouse |
Alysha A Sultan, Mikaela K Dimick, Clement C Zai, James L Kennedy, Bradley J MacIntosh, Benjamin I Goldstei. The association of CNR1 genetic variants with resting-state functional connectivity in youth bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 71. 2023-03-27. PMID:36972648. |
g-allele was associated with positive connectivity in bd and negative connectivity in hc for: right hippocampal seed with left central opercular cortex (p = 0.001), and left nac seed with left middle temporal cortex (p = 0.002). |
2023-03-27 |
2023-08-14 |
human |
Yi-Fang Wu, Kai-Yan Jin, Da-Peng Wang, Qi Lin, Jun Sun, Shao-Hua Su, Jian Ha. VEGF loaded nanofiber membranes inhibit chronic cerebral hypoperfusion-induced cognitive dysfunction by promoting HIF-1a/VEGF mediated angiogenesis. Nanomedicine : nanotechnology, biology, and medicine. 2022-12-22. PMID:36549557. |
vegf-nfms sticking decreased the number of tunel-positive cells in surgical temporal cortex, ameliorated impaired synaptic plasticity, and inhibited the release of pro-inflammatory cytokines and the activation of microglia and astrocytes in surgical temporal cortex and hippocampus. |
2022-12-22 |
2023-08-14 |
rat |
Sebastiaan Moonen, Marta J Koper, Evelien Van Schoor, Jolien M Schaeverbeke, Rik Vandenberghe, Christine A F von Arnim, Thomas Tousseyn, Bart De Strooper, Dietmar Rudolf Tha. Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons. Acta neuropathologica. 2022-12-09. PMID:36481964. |
cleaved gsdmd was detected in microglia, but also in astrocytes and in few pyramidal neurons in the first sector of the cornu ammonis (ca1) of the hippocampus and the temporal cortex of brodmann area 36. |
2022-12-09 |
2023-08-14 |
human |
Yao Lin, Man Ding, Qiaoyu Gong, Zheman Xia. Downregulation of GABAARα1 Aggravates Comorbidity of Epilepsy and Migraine via the TLR4 Signaling Pathway. Brain sciences. vol 12. issue 11. 2022-11-11. PMID:36358363. |
western blot and immunofluorescence staining were used to detect the protein expression levels of tlr4 and gabaarα1 in the temporal cortex, hippocampus, trigeminal ganglion, and medullary dorsal horn. |
2022-11-11 |
2023-08-14 |
rat |