| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paige L Graney, Evelyn L Sarno, Jessie E Miller, Christine K Wagne. Implications of Developmental 17-OHPC Exposure on the Mesocorticolimbic Serotonergic and Dopaminergic Pathways and Adolescent Mood-Related Behavior in Rats. Developmental psychobiology. vol 66. issue 6. 2024-08-21. PMID:39164823. |
developmental 17-ohpc exposure significantly increased the density of serotonin transporter-ir fibers in ca1, ca2/3, and the suprapyramidal blade of dentate gyrus in hippocampus and significantly reduced the density of th-ir fibers within the nucleus accumbens shell in males but had no effect in females during adolescence. |
2024-08-21 |
2024-08-23 |
rat |
| Ankangzhi Ma, Yawei Mu, Zixuan Wei, Menghan Sun, Junjie Li, Hanyang Jiang, Cuiqing Zhu, Xianhua Che. SRSF10 regulates migration of neural progenitor cells and granule cells and affects the formation of dentate gyrus during the development of mouse hippocampus. Neuroscience. 2024-07-03. PMID:38960088. |
in this study, using srsf10 conditional knock-out mice in neural progenitor cells (npcs), we found that dysfunction of srsf10 leads to developmental defects in the dentate gyrus of hippocampus, which manifests as the reduced length and wider suprapyramidal blade and infrapyramidal blade.furthermore, we proved that loss of srsf10 in npcs caused inhibition of the differentiation activity and the abnormal migration of npcs and granule cells, resulting in reduced granule cells and more ectopic granule cells dispersed in the molecular layer and hilus. |
2024-07-03 |
2024-07-10 |
mouse |
| Poonam Mishra, Rishikesh Narayana. Heterogeneities in intrinsic excitability and frequency-dependent response properties of granule cells across the blades of the rat dentate gyrus. Journal of neurophysiology. vol 123. issue 2. 2021-05-12. PMID:31913748. |
the dentate gyrus (dg), the input gate to the hippocampus proper, is anatomically segregated into three different sectors, namely, the suprapyramidal blade, the crest region, and the infrapyramidal blade. |
2021-05-12 |
2023-08-13 |
rat |
| Takeshi Uemori, Keiko Toda, Tatsunori Sek. Seizure severity-dependent selective vulnerability of the granule cell layer and aberrant neurogenesis in the rat hippocampus. Hippocampus. vol 27. issue 10. 2018-05-18. PMID:28608989. |
in rats with frequent severe seizures, we found a clear loss of prox1 and neun expression in the dentate granule cell layer (gcl), which was confined mainly to the suprapyramidal blade of the gcl at the septal and middle regions of the septotemporal axis of the hippocampus. |
2018-05-18 |
2023-08-13 |
human |
| Takeshi Uemori, Keiko Toda, Tatsunori Sek. Seizure severity-dependent selective vulnerability of the granule cell layer and aberrant neurogenesis in the rat hippocampus. Hippocampus. vol 27. issue 10. 2018-05-18. PMID:28608989. |
in rats with no or slight loss of prox1 expression in the gcl, ectopic immature neurons were detected in the molecular layer of the suprapyramidal blade in addition to the hilus, and formed chainlike aggregated structures along the blood vessels up to the hippocampal fissure, suggesting that newly generated neurons migrate at least partially along blood vessels to the hippocampal fissure. |
2018-05-18 |
2023-08-13 |
human |