| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammed Zacky Ariffin, Si Yun Ng, Hamzah Nadia, Darrel Koh, Natasha Loh, Naomi Michiko, Sanjay Khann. Neurokinin1 - cholinergic receptor mechanisms in the medial Septum-Dorsal hippocampus axis mediates experimental neuropathic pain. Neurobiology of pain (Cambridge, Mass.). vol 16. 2024-09-03. PMID:39224764. |
the neurokinin-1 receptors (nk1rs) in the forebrain medial septum (ms) region are localized exclusively on cholinergic neurons that partly project to the hippocampus and the cingulate cortex (cg), regions implicated in nociception. |
2024-09-03 |
2024-09-05 |
rat |
| Lila Harris-Blum, Zachary Smith, Richard J Ortiz, Deepti Athreya, Arnold Chang, Praveen P Kulkarni, Craig F Ferri. Developmental changes in brain structure and function following exposure to oral LSD during adolescence. Scientific reports. vol 14. issue 1. 2024-08-11. PMID:39128924. |
the functional connectivity between forebrain white matter tracts and sensorimotor cortices and hippocampus was reduced with multidose lsd exposure. |
2024-08-11 |
2024-08-14 |
mouse |
| Lila Harris-Blum, Zachary Smith, Richard J Ortiz, Deepti Athreya, Arnold Chang, Praveen P Kulkarni, Craig F Ferri. Developmental changes in brain structure and function following exposure to oral LSD during adolescence. Scientific reports. vol 14. issue 1. 2024-08-11. PMID:39128924. |
the reduction in connectivity in forebrain white matter tracts with multidose lsd and consolidation around sensorimotor and hippocampal brain areas requires a battery of tests to understand the consequences of these changes on behavior. |
2024-08-11 |
2024-08-14 |
mouse |
| Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |
| Dae Won Kim, Tae-Kyeong Lee, Ji Hyeon Ahn, Se-Ran Yang, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won, Il Jun Kang, Joon Ha Par. Porphyran Attenuates Neuronal Loss in the Hippocampal CA1 Subregion Induced by Ischemia and Reperfusion in Gerbils by Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation. Marine drugs. vol 22. issue 4. 2024-04-26. PMID:38667787. |
the aim of this study was to examine the neuroprotective effects of porphyran against brain ir injury and its underlying mechanisms using a gerbil model of transient forebrain ischemia (ir in the forebrain), which results in pyramidal cell (principal neuron) loss in the cornu ammonis 1 (ca1) subregion of the hippocampus on day 4 after ir. |
2024-04-26 |
2024-04-28 |
Not clear |
| Sarah Buchholz, Michael Bell-Simons, Natja Haag, Hans Zempe. Tracking Tau in Neurons: How to Grow, Fix, and Stain Primary Neurons for the Investigation of Tau in All Developmental Stages. Methods in molecular biology (Clifton, N.J.). vol 2754. 2024-03-21. PMID:38512686. |
here, we describe (i) a relatively cheap and easy cell culture procedure for the cultivation of forebrain neurons from embryonic mice (e13.5) based on a commercially available neuronal supplement (ns21), (ii) a protocol for the cultivation of hippocampal and cortical neurons from postnatal (p0-p3) animals, and (iii) basic fixation and immunofluorescence techniques for the staining of neuronal markers and endogenous tau. |
2024-03-21 |
2024-03-24 |
mouse |
| Giulia Natali, Caterina Michetti, Alicja Krawczun-Rygmaczewska, Thomas Floss, Fabrizia Cesca, Fabio Benfenat. Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling. Frontiers in cellular neuroscience. vol 17. 2023-11-30. PMID:38034589. |
as forebrain excitatory neurons are the common final pathway of seizure susceptibility, we investigated the role of rest in epilepsy by inducing rest conditional knockout (rest-cko) specifically in excitatory neurons of the hippocampus. |
2023-11-30 |
2023-12-10 |
Not clear |
| Baicheng Zhao, Hang Zhang, Ying Liu, Gaoyu Zu, Yuxiao Zhang, Jiayi Hu, Shuai Liu, Linya Yo. Forebrain excitatory neuron-specific loss of Brpf1 attenuates excitatory synaptic transmission and impairs spatial and fear memory. Neural regeneration research. vol 19. issue 5. 2023-10-20. PMID:37862219. |
our previous work revealed strong and specific expression of brpf1 in both the postnatal and adult forebrain, especially the hippocampus, which has essential roles in learning and memory. |
2023-10-20 |
2023-11-08 |
mouse |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Alexander Baxter, Chloe L Karaskiewicz, Lindsey A Campbell, Erin L Kinnally, Emilio Ferrer, Adele H M Seelke, Sara M Freeman, Karen L Bale. Parental experience is linked with lower vasopressin receptor 1a binding and decreased postpartum androgens in titi monkeys. Journal of neuroendocrinology. 2023-06-02. PMID:37267441. |
in studies 1 and 2, we used receptor autoradiography to correlate arginine vasopressin receptor 1a (avpr1a) binding in the hippocampus (study 1, n = 10) and the rest of the forebrain (study 2, n = 23) with parental status, parental experience, parity, infant carrying, and pair affiliation. |
2023-06-02 |
2023-08-14 |
monkey |
| Nanna Bertin Markussen, Rasmus West Knopper, Stine Hasselholt, Christian Stald Skoven, Jens Randel Nyengaard, Leif Østergaard, Brian Hanse. Locus coeruleus ablation in mice: protocol optimization, stereology and behavioral impact. Frontiers in cellular neuroscience. vol 17. 2023-05-15. PMID:37180952. |
the locus coeruleus (lc) is in the brainstem and supplies key brain structures with noradrenaline, including the forebrain and hippocampus. |
2023-05-15 |
2023-08-14 |
mouse |
| Mikel L Olson, Bretton Badenoch, Megan Blatti, Christine Buching, Nic Gleww. Muscarinic Cholinergic Receptor Antagonism Impairs Spatial Memory Retrieval and Minimizes Retrieval-Induced Alterations in Matrix Metalloproteinase-9. Behavioural brain research. 2023-04-29. PMID:37119978. |
cholinergic dysfunction in the hippocampus causes memory impairment, and degradation of the forebrain cholinergic system has been implicated in several neurological disorders. |
2023-04-29 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
the midbrain raphe serotonin (5ht) neurons provide the main ascending serotonergic projection to the forebrain, including hippocampus, which has a role in the pathophysiology of depressive disorder. |
2023-04-28 |
2023-08-14 |
rat |
| Nima Salimi-Nezhad, Stephan Missault, Anaïs Notario Reinoso, Atefe Hassani, Mahmood Amiri, Georgios A Keliri. The impact of selective and non-selective medial septum stimulation on hippocampal neuronal oscillations: A study based on modeling and experiments. Neurobiology of disease. 2023-02-23. PMID:36822547. |
the medial septum (ms) in the forebrain provides major cholinergic input to the hpc and has been shown to play a significant role in generating oscillations in hippocampal neurons. |
2023-02-23 |
2023-08-14 |
rat |
| Victoria Macht, Ryan Vetreno, Natalie Elchert, Rachael Fisher, Fulton Crew. Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure. Alcoholism, clinical and experimental research. 2023-02-17. PMID:36799290. |
adolescent intermittent ethanol (aie) exposure causes long-term changes in the brain and behavior of adult male rodents, including persistent induction of innate immune pathways, reductions in hippocampal neurogenic and forebrain cholinergic neuronal markers, and reversal learning deficits. |
2023-02-17 |
2023-08-14 |
rat |
| Victoria Macht, Ryan Vetreno, Natalie Elchert, Rachael Fisher, Fulton Crew. Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure. Alcoholism, clinical and experimental research. 2023-02-17. PMID:36799290. |
the current study tests the hypothesis that proinflammatory induction mediates aie-induced (1) loss of adult neurogenesis (i.e., doublecortin (dcx) expressing immature neurons), (2) reductions in forebrain and hippocampal cholinergic markers, and (3) reversal learning deficits. |
2023-02-17 |
2023-08-14 |
rat |
| Tae-Kyeong Lee, Sung-Su Kim, Ji-Won Lee, Dae Won Kim, Jae-Chul Lee, Jong-Dai Kim, Soo Young Choi, Seongkweon Hong, Moo-Ho Won, Yang Hee Ki. Brain Factor-7® Improves Cognitive Impairment Following Transient Ischemia and Reperfusion Injury in Gerbil Forebrain through Promoting Remyelination and Restoring Cholinergic and Glutamatergic Neurotransmission in the Hippocampus. Frontiers in bioscience (Landmark edition). vol 27. issue 12. 2023-01-10. PMID:36624955. |
brain factor-7® improves cognitive impairment following transient ischemia and reperfusion injury in gerbil forebrain through promoting remyelination and restoring cholinergic and glutamatergic neurotransmission in the hippocampus. |
2023-01-10 |
2023-08-14 |
Not clear |
| Moorthi Ponnusamy, Shuai Wang, Melike Yuksel, Mitchell T Hansen, Danielle M Blazier, Joseph D McMillan, Xiaolin Zhang, Eric B Dammer, Lisa Collier, Gopal Thinakara. Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model. Brain : a journal of neurology. 2022-09-04. PMID:36059072. |
loss of forebrain bin1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model. |
2022-09-04 |
2023-08-14 |
mouse |
| Moorthi Ponnusamy, Shuai Wang, Melike Yuksel, Mitchell T Hansen, Danielle M Blazier, Joseph D McMillan, Xiaolin Zhang, Eric B Dammer, Lisa Collier, Gopal Thinakara. Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model. Brain : a journal of neurology. 2022-09-04. PMID:36059072. |
we conclude that forebrain neuronal bin1 expression promotes hippocampal tau pathogenesis and neuroinflammation. |
2022-09-04 |
2023-08-14 |
mouse |
| A Gómez, B Rodríguez-Expósito, F M Ocaña, C Salas, F Rodrígue. Trace classical conditioning impairment after lesion of the lateral part of the goldfish telencephalic pallium suggests a long ancestry of the episodic memory function of the vertebrate hippocampus. Brain structure & function. 2022-08-25. PMID:36006500. |
on the contrary, an alternative hypothesis holds that the hippocampus of ancestral vertebrates originally encoded both the spatial and temporal dimensions of relational memories since its evolutionary appearance, thus suggesting that the episodic-like memory function of the hippocampus could be the primitive condition in vertebrate forebrain evolution. |
2022-08-25 |
2023-08-14 |
Not clear |