All Relations between hippocampus and molecular layer

Publication Sentence Publish Date Extraction Date Species
Ankangzhi Ma, Yawei Mu, Zixuan Wei, Menghan Sun, Junjie Li, Hanyang Jiang, Cuiqing Zhu, Xianhua Che. SRSF10 regulates migration of neural progenitor cells and granule cells and affects the formation of dentate gyrus during the development of mouse hippocampus. Neuroscience. 2024-07-03. PMID:38960088. in this study, using srsf10 conditional knock-out mice in neural progenitor cells (npcs), we found that dysfunction of srsf10 leads to developmental defects in the dentate gyrus of hippocampus, which manifests as the reduced length and wider suprapyramidal blade and infrapyramidal blade.furthermore, we proved that loss of srsf10 in npcs caused inhibition of the differentiation activity and the abnormal migration of npcs and granule cells, resulting in reduced granule cells and more ectopic granule cells dispersed in the molecular layer and hilus. 2024-07-03 2024-07-10 mouse
Jeonghwan Lee, Gawon Ju, Hyemi Park, Seungwon Chung, Jung-Woo Son, Chul-Jin Shin, Sang Ick Lee, Siekyeong Ki. Hippocampal Subfields and White Matter Connectivity in Patients with Subclinical Geriatric Depression. Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326285. our findings indicated that the volumes of whole bilateral hippocampus, cornus ammonis (ca) 1, molecular layer, left subiculum, ca3, hippocampal tail, right ca4, and granule cell/molecular layers of the dentate gyrus (gc-ml-dg) were significantly smaller in the subclinical depression group than in the control group. 2022-03-25 2023-08-13 human
Jeonghwan Lee, Gawon Ju, Hyemi Park, Seungwon Chung, Jung-Woo Son, Chul-Jin Shin, Sang Ick Lee, Siekyeong Ki. Hippocampal Subfields and White Matter Connectivity in Patients with Subclinical Geriatric Depression. Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326285. in the subclinical depression group, verbal learning was positively correlated with the volumes of the ca1, gc-ml-dg, molecular layer, and whole hippocampus in the right hemisphere. 2022-03-25 2023-08-13 human
Katherine M Fronczak, Youming Li, Jeremy Henchir, C Edward Dixon, Shaun W Carlso. Reductions in Synaptic Vesicle Glycoprotein 2 Isoforms in the Cortex and Hippocampus in a Rat Model of Traumatic Brain Injury. Molecular neurobiology. vol 58. issue 11. 2021-11-20. PMID:34435329. immunohistochemical staining and quantitative intensity measurements completed at 14 days post-injury revealed reduced sv2a immunoreactivity in all hippocampal subregions and reduced sv2b immunoreactivity in the molecular layer after cci. 2021-11-20 2023-08-13 rat
Natsu Sasaki-Takahashi, Hiroshi Shinohara, Seiji Shioda, Tatsunori Sek. The polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy. Hippocampus. vol 30. issue 3. 2021-09-13. PMID:32101365. in the adult mouse hippocampus, new neurons are produced by radial glia-like (rgl) neural stem cells in the subgranular zone, which extend their apical processes toward the molecular layer, and express the astrocyte marker glial fibrillary acidic protein, but not the astrocyte marker s100β. 2021-09-13 2023-08-13 mouse
Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Horng-Der Shen, Li-Fen Chen, Jen-Chuen Hsie. Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain. NeuroImage. Clinical. vol 30. 2021-07-30. PMID:33561695. significant interactions between pdm severity and bdnf val66met genotype were observed in the right whole hippocampus, subiculum, and molecular layer. 2021-07-30 2023-08-13 human
Frédéric Briend, Eric A Nelson, Omar Maximo, William P Armstrong, Nina V Kraguljac, Adrienne C Laht. Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32398671. smaller whole hippocampal volume, as well as ca1, molecular layer, subiculum, presubiculum, and hippocampal tail volumes were significantly associated with longer dup. 2021-06-18 2023-08-13 human
Jon Egaña-Huguet, Itziar Bonilla-Del Río, Sonia M Gómez-Urquijo, Amaia Mimenza, Miquel Saumell-Esnaola, Leire Borrega-Roman, Gontzal García Del Caño, Joan Sallés, Nagore Puente, Inmaculada Gerrikagoitia, Izaskun Elezgarai, Pedro Grande. The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus. Frontiers in neuroanatomy. vol 15. 2021-03-12. PMID:33692673. in the hippocampal dentate gyrus, trpv1 localizes to dendritic spines and dendrites postsynaptic to excitatory synapses in the molecular layer (ml). 2021-03-12 2023-08-13 mouse
Ruiqi Pang, Xiaofan Wang, Zhiqiang Du, Feifei Pei, Zhiyue Li, Libing Sun, Shuying Wang, Yingnan Peng, Xupeng Lu, Xiaoqun Gao, Cheng Chan. The distribution and density of monocarboxylate transporter 2 in cerebral cortex, hippocampus and cerebellum of wild-type mice. Journal of anatomy. vol 236. issue 2. 2021-03-09. PMID:31713246. the mct2 density on the end feet of astrocytes of molecular layer was lower than in hippocampus, but the postsynaptic densities (psds) of asymmetric synapses in the molecular layer exhibited a high density using immunogold post-embedding electron microscopic techniques. 2021-03-09 2023-08-13 mouse
Maria-Eleni Dounavi, Elijah Mak, Katie Wells, Karen Ritchie, Craig W Ritchie, Li Su, John T O' Brie. Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. Neurobiology of aging. vol 91. 2020-10-30. PMID:32311609. the molecular layer may be the first hippocampal region to demonstrate volumetric alterations in subjects at risk of dementia. 2020-10-30 2023-08-13 human
Daniel Carey, Hugh Nolan, Rose Anne Kenny, James Meane. Dissociable age and memory relationships with hippocampal subfield volumes in vivo:Data from the Irish Longitudinal Study on Ageing (TILDA). Scientific reports. vol 9. issue 1. 2020-10-16. PMID:31358771. fully-adjusted models revealed that immediate and delayed recall were both associated with cubic fits with respect to volume of subfields ca1, ca2/3, ca4, molecular layer, and granule cell layer of dentate gyrus; moreover, these effects were partly dissociable from quadratic age trends, observed for subiculum, molecular layer, hippocampal tail, and ca1. 2020-10-16 2023-08-13 Not clear
Christin M Godale, Steve C Danze. Signaling Pathways and Cellular Mechanisms Regulating Mossy Fiber Sprouting in the Development of Epilepsy. Frontiers in neurology. vol 9. 2020-10-01. PMID:29774009. the sprouting of hippocampal dentate granule cell axons, termed mossy fibers, into the dentate inner molecular layer is one of the most consistent findings in tissue from patients with mesial temporal lobe epilepsy. 2020-10-01 2023-08-13 Not clear
Valentyna Dubovyk, Denise Manahan-Vaugha. Gradient of Expression of Dopamine D2 Receptors Along the Dorso-Ventral Axis of the Hippocampus. Frontiers in synaptic neuroscience. vol 11. 2020-09-30. PMID:31680927. effects were very consistent: the molecular layer, granule cell layer and polymorphic layer of the dg exhibited higher d2r levels in the ventral compared to dorsal hippocampus. 2020-09-30 2023-08-13 Not clear
Nuo Yang, Yan-Chao Li, Tian-Qing Xiong, Ling-Meng Chen, Yu Zhai, Jian-Min Liang, Yun-Peng Hao, Di-Hui Ma, Yan-Feng Zhan. Dexamethasone ameliorates the damage of hippocampal filamentous actin cytoskeleton but is not sufficient to cease epileptogenesis in pilocarpine induced epileptic mice. Epilepsy research. vol 154. 2020-07-13. PMID:31022637. however, the number of znt3 positive particles in the molecular layer in the hippocampus of pilocarpine epileptic mice was not altered after dex treatment. 2020-07-13 2023-08-13 mouse
Shweta Prasad, Apurva Shah, Ketaki Swapnil Bhalsing, Keshav J Kumar, Jitender Saini, Madhura Ingalhalikar, Pramod Kumar Pa. Abnormal hippocampal subfields are associated with cognitive impairment in Essential Tremor. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 5. 2020-07-01. PMID:30888510. significant atrophy of the left subiculum, ca4, granule-cell layer of dentate gyrus, right molecular layer, and hypertrophy of bilateral parasubiculum, right hippocampus-amygdala-transition-area, bilateral hippocampal tail (ht) and widening of right hippocampal fissure was observed in et. 2020-07-01 2023-08-13 Not clear
Natalie M Zahr, Kilian M Pohl, Manojkumar Saranathan, Edith V Sullivan, Adolf Pfefferbau. Hippocampal subfield CA2+3 exhibits accelerated aging in Alcohol Use Disorder: A preliminary study. NeuroImage. Clinical. vol 22. 2020-01-17. PMID:30904825. freesurfer 6.0 hippocampal subfield analysis produced 12 subfields: parasubiculum; presubiculum; subiculum; ca1; ca2+3; ca4; gc-ml-dg (granule cell (gc) and molecular layer (ml) of the dentate gyrus (dg)); molecular layer; hippocampus-amygdala-transition-area (hata); fimbria; hippocampal tail; hippocampal fissure; and whole volume for left and right hippocampi. 2020-01-17 2023-08-13 human
Khushboo Srivastava, Ratnakar Tripathi, Rajnikant Mishr. Age-dependent alterations in expression and co-localization of Pax6 and Ras-GAP in brain of aging mice. Journal of chemical neuroanatomy. vol 92. 2019-10-22. PMID:29787792. the co-localization of pax6 and ras-gap were observed in dentate gyrus (dg) and sub-granular zone (sgz) of hippocampus, in glomerular (glla) and mitral cells (mice) of olfactory lobe, granular cells (grce), purkinje cell (puce) and molecular cell layer (mola) of cerebellum, internal plexiform layer (inpl), molecular layer (mola) of cerebral cortex and in intercalated cells of amygdala (itc), caudate nucleus regions in brain of aging mice. 2019-10-22 2023-08-13 mouse
Kyoung-Sae Na, Eunsoo Won, June Kang, Aram Kim, Sunyoung Choi, Yong-Ku Kim, Min-Soo Lee, Byung-Joo Ha. Interaction effects of oxytocin receptor gene polymorphism and depression on hippocampal volume. Psychiatry research. Neuroimaging. vol 282. 2019-07-25. PMID:30384146. there were significant interactions between oxtr allele type and diagnosis of mdd on the 7 hippocampal subfield volumes, such as left presubiculum, left subiculum, left molecular, right cornus ammonis 1, right granule cells in the molecular layer of the dentate gyrus, right molecular layer, and right subiculum. 2019-07-25 2023-08-13 Not clear
Lianne J Trigiani, Jessika Royea, María Lacalle-Aurioles, Xin-Kang Tong, Edith Hame. Pleiotropic Benefits of the Angiotensin Receptor Blocker Candesartan in a Mouse Model of Alzheimer Disease. Hypertension (Dallas, Tex. : 1979). vol 72. issue 5. 2019-05-13. PMID:30354809. candesartan exerted restorative effects on the reduced number of ki67-immunopositive proliferating cells in the granule cell layer of the hippocampus but not on that of dcx (doublecortin)-positive immature granule cells, despite normalizing the length of their dendritic projections in the molecular layer. 2019-05-13 2023-08-13 mouse
Panos Theofilas, Christian Steinhäuser, Martin Theis, Amin Derouich. Morphological study of a connexin 43-GFP reporter mouse highlights glial heterogeneity, amacrine cells, and olfactory ensheathing cells. Journal of neuroscience research. vol 95. issue 11. 2018-05-18. PMID:28370142. applying anti-gfp, all cell types related to astroglia were positive-namely, protoplasmic astrocytes in the hippocampus, cortex, thalamus, spinal cord, olfactory bulb, cerebellum with bergmann glia and astrocytes also in the molecular layer, and retinal müller cells and astrocytes. 2018-05-18 2023-08-13 mouse