| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyung Oh Jeon, Oc-Hee Kim, Soo Yeon Seo, Jaesuk Yun, Choon-Gon Jang, Ri-Na Lim, Tae Wan Kim, Chae Ha Yang, Seong Shoon Yoon, Eun Young Jan. The psychomotor, reinforcing, and discriminative stimulus effects of synthetic cathinone mexedrone in male mice and rats. European journal of pharmacology. 2024-03-02. PMID:38431243. |
in addition, serotonin transporter (sert) levels were measured in the synaptosome of the dorsal striatum, and serotonin (5-ht) levels were measured in the dorsal striatum of acute mexedreone (50 mg/kg)-treated mice. |
2024-03-02 |
2024-03-06 |
mouse |
| Kyung Oh Jeon, Oc-Hee Kim, Soo Yeon Seo, Jaesuk Yun, Choon-Gon Jang, Ri-Na Lim, Tae Wan Kim, Chae Ha Yang, Seong Shoon Yoon, Eun Young Jan. The psychomotor, reinforcing, and discriminative stimulus effects of synthetic cathinone mexedrone in male mice and rats. European journal of pharmacology. 2024-03-02. PMID:38431243. |
acute mexedrone significantly increased c-fos expression in the dorsal striatum and decreased sert levels in the synaptosome of the dorsal striatum of mice, resulting in elevation of 5-ht levels. |
2024-03-02 |
2024-03-06 |
mouse |
| Yuki Moriya, Yoshiyuki Kasahara, Kana Ishihara, Frank Scott Hall, Yoko Hagino, René Hen, Kazutaka Ikeda, George R Uhl, Ichiro Sor. Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization. Behavioural pharmacology. 2023-09-05. PMID:37668157. |
to clarify the action of meth in 5-ht1b ko mice the effects of meth on extracellular levels of da (daec) and 5-ht (5-htec) in the caudate putamen (cpu) and the nucleus accumbens (nac) were examined. |
2023-09-05 |
2023-09-07 |
mouse |
| Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. |
we exposed female rats to the aba paradigm and measured the levels of da, 5-ht, and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxyindoleacetic acid (5-hiaa), and dopaminergic type 2 (d2) receptors density in feeding- and reward-implicated brain regions (i.e., cerebral cortex, cx; prefrontal cortex, pfc; caudate putamen, cpu; nucleus accumbens, nacc; amygdala, amy; hypothalamus, hyp; hippocampus, hipp). |
2023-03-02 |
2023-08-14 |
rat |
| Kristi Liiver, Sophie Imbeault, Marianna Školnaja, Tanel Kaart, Margus Kanarik, Karita Laugus, Jade De Wettinck, Aleksander Pulver, Ruth Shimmo, Jaanus Harr. Active vs passive novelty-related strategies: Sex differences in exploratory behaviour and monoaminergic systems. Behavioural brain research. 2023-01-14. PMID:36641084. |
male rats had lower levels of dopamine (da) in frontal cortex, and higher levels of 3,4-dihydroxyphenylacetic acid (dopac) in raphe area; higher levels of serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in dorsal striatum but lower levels of 5-ht and 5-hiaa in locus coeruleus area, 5-hiaa levels were also lower in hippocampus as compared to females. |
2023-01-14 |
2023-08-14 |
rat |
| Misato Ichise, Kazuto Sakoori, Kei-Ichi Katayama, Naoko Morimura, Kazuyuki Yamada, Hiroki Ozawa, Hayato Matsunaga, Minoru Hatayama, Jun Arug. Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics. Frontiers in molecular neuroscience. vol 15. 2022-05-26. PMID:35615067. |
dopamine metabolite content was decreased in the dorsal striatum and hypothalamus, and serotonin turnover increased in the dorsal striatum. |
2022-05-26 |
2023-08-13 |
mouse |
| Alexander G Zestos, Harmain Rafi, Negar G Ardabil. Carbon Fiber Multielectrode Arrays for Multiplexing Neurotransmitter Detection in Heterogeneous Brain Regions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556754. |
we mapped out endogenous levels of neurochemicals such as dopamine, serotonin, and adenosine in regions including the ventral tegmental area, caudate putamen, raphe nuclei, and substantia nigra. |
2022-05-13 |
2023-08-13 |
mouse |
| Rebeca Vindas-Smith, Dayana Quesada, Mónica I Hernández-Solano, Maripaz Castro, Andrey Sequeira-Cordero, Jaime Fornaguera, Georgina Gómez, Juan C Brene. Fat intake and obesity-related parameters predict striatal BDNF gene expression and dopamine metabolite levels in cafeteria diet-fed rats. Neuroscience. 2022-04-10. PMID:35398176. |
the cafeteria diet increased bdnf expression in the dorsal striatum (ds), and norepinephrine, 5-ht, trkb, creb, and dnmt3a levels in the hippocampus. |
2022-04-10 |
2023-08-13 |
rat |
| Guillermo Valera-Marín, Larry J Young, Francisco Camacho, Raúl G Paredes, Verónica M Rodríguez, Néstor F Díaz, Wendy Portill. Raised without a father: monoparental care effects over development, sexual behavior, sexual reward, and pair bonding in prairie voles. Behavioural brain research. vol 408. 2021-12-07. PMID:33775781. |
we also measured dopamine and serotonin concentration in the nucleus accumbens (ventral striatum) and dorsal striatum after cohabitation and mating (cm) to determine if differences in these neurotransmitters could underlie the delay in pair bond formation in mp voles. |
2021-12-07 |
2023-08-13 |
Not clear |
| Guillermo Valera-Marín, Larry J Young, Francisco Camacho, Raúl G Paredes, Verónica M Rodríguez, Néstor F Díaz, Wendy Portill. Raised without a father: monoparental care effects over development, sexual behavior, sexual reward, and pair bonding in prairie voles. Behavioural brain research. vol 408. 2021-12-07. PMID:33775781. |
no differences in dopamine, serotonin or their metabolites were found in the dorsal striatum. |
2021-12-07 |
2023-08-13 |
Not clear |
| Andrey Sequeira-Cordero, Juan C Brene. Time-dependent changes in striatal monoamine levels and gene expression following single and repeated amphetamine administration in rats. European journal of pharmacology. vol 904. 2021-11-05. PMID:33961872. |
prone subjects characterized by having reduced striatal 5-ht metabolism, higher accumbal bdnf and trkb expression, and lower levels of creb in the dorsal striatum and p250gap in both regions. |
2021-11-05 |
2023-08-13 |
human |
| Tori L Schaefer, Curtis E Grace, Matthew R Skelton, Devon L Graham, Gary A Gudelsky, Charles V Vorhees, Michael T William. Neonatal citalopram treatment inhibits the 5-HT depleting effects of MDMA exposure in rats. ACS chemical neuroscience. vol 3. issue 1. 2021-10-21. PMID:22582138. |
in a series of experiments we evaluated the effects of different doses and dose regimens of cit on mdma-induced 5-ht depletions in three brain regions (hippocampus, entorhinal cortex, and neostriatum) at three time-points (p12, p16, p21) during the treatment interval (p11-20) known to induce behavioral alterations when animals are tested as adults. |
2021-10-21 |
2023-08-12 |
human |
| Sofi da Cunha-Bang, Gitte Moos Knudse. The Modulatory Role of Serotonin on Human Impulsive Aggression. Biological psychiatry. vol 90. issue 7. 2021-09-27. PMID:34266672. |
interventions that (presumably) alter serotonin levels have effects on brain activity within brain regions involved in impulsive aggression, notably the amygdala, dorsal striatum, anterior cingulate, insula, and prefrontal cortex. |
2021-09-27 |
2023-08-13 |
human |
| Milo Grotell, Bjørnar den Hollander, Aaro Jalkanen, Essi Törrönen, Jouni Ihalainen, Elena de Miguel, Mateusz Dudek, Mikko I Kettunen, Petri Hyytiä, Markus M Forsberg, Esko Kankuri, Esa R Korp. Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity. Frontiers in pharmacology. vol 12. 2021-05-18. PMID:33995109. |
these effects were most profound in brain regions which are known to have high dopamine and serotonin activities including hippocampus, nucleus accumbens and caudate-putamen. |
2021-05-18 |
2023-08-13 |
rat |
| Ping K Yip, Magdalena Schmitzberger, Mohammed Al-Hasan, Julia George, Elina Tripoliti, Adina T Michael-Titus, David Clayton, John V Priestle. Serotonin Expression in the Song Circuitry of Adult Male Zebra Finches. Neuroscience. vol 444. 2021-05-14. PMID:32590039. |
mean serotonin expression was highest in interfacial nucleus (nif) and lower in the other song nuclei in the following order (in order of highest first): interfacial nucleus (nif) > area x > dorsomedial part of the intercollicular nucelus (dm) > robust nucleus of the archistriatum (ra) > lateral magnocellular nucleus of the anterior neostriatum (lman) > ventral respiratory group (vrg) > dorsolateral nucleus of the medial thalamus (dlm) > the nucleus hvc (proper name) > tracheosyringeal motor nucleus (nxiits). |
2021-05-14 |
2023-08-13 |
Not clear |
| Daisuke Matsunaga, Hikaru Nakagawa, Takayuki Ishiwat. Difference in the brain serotonin and its metabolite level and anxiety-like behavior between forced and voluntary exercise conditions in rats. Neuroscience letters. vol 744. 2021-04-30. PMID:33373674. |
in the paraventricular hypothalamic nucleus and caudate putamen, only 5-ht levels were increased in the v-ex group. |
2021-04-30 |
2023-08-13 |
rat |
| Meiju Zhu, Hongzhu Zhu, Xiaomin Ding, Shaosheng Liu, Yuanhua Zo. Analysis of the anti-fatigue activity of polysaccharides from Spirulina platensis: role of central 5-hydroxytryptamine mechanisms. Food & function. vol 11. issue 2. 2020-10-19. PMID:32057057. |
this study evaluated the effects of polysaccharides from spirulina platensis (psp) on endurance during treadmill exercise; levels of some biochemical indicators including hemoglobin (hb), lactic acid (la), creatine kinase (ck), and blood urea nitrogen (bun); concentrations of 5-hydroxytryptamine (5-ht); and expressions of second isoforms of tryptophan hydroxylase (tph2) and serotonergic type 1b inhibitory autoreceptor (5-ht1b) in the caudate putamen of exercising rats. |
2020-10-19 |
2023-08-13 |
rat |
| Meiju Zhu, Hongzhu Zhu, Xiaomin Ding, Shaosheng Liu, Yuanhua Zo. Analysis of the anti-fatigue activity of polysaccharides from Spirulina platensis: role of central 5-hydroxytryptamine mechanisms. Food & function. vol 11. issue 2. 2020-10-19. PMID:32057057. |
the results demonstrated that psp prolonged the time to exhaustion during the treadmill exercise; increased hb levels; decreased la, bun, and ck levels in the blood; suppressed the exercise-induced increase of 5-ht concentrations and tph2 expression; and prevented the exercise-induced decrease of 5-ht1b expression in the caudate putamen. |
2020-10-19 |
2023-08-13 |
rat |
| Meiju Zhu, Hongzhu Zhu, Xiaomin Ding, Shaosheng Liu, Yuanhua Zo. Analysis of the anti-fatigue activity of polysaccharides from Spirulina platensis: role of central 5-hydroxytryptamine mechanisms. Food & function. vol 11. issue 2. 2020-10-19. PMID:32057057. |
these results suggest that the mechanism of promotion of physical performance by psp might be related to increase in hb levels; decrease in la, bun, and ck levels in the blood; inhibition of the exercise-induced 5-ht and tph2 expressions; and the increase in the 5-ht1b expression in the caudate putamen of exercised rats. |
2020-10-19 |
2023-08-13 |
rat |
| Arnauld Belmer, Kate Beecher, Angela Jacques, Omkar L Patkar, Florian Sicherre, Selena E Bartlet. Axonal Non-segregation of the Vesicular Glutamate Transporter VGLUT3 Within Serotonergic Projections in the Mouse Forebrain. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31133811. |
therefore, we combined immunohistochemistry, high resolution confocal imaging, and 3d-reconstruction techniques to map and quantify the distribution of vglut3 immunoreactive boutons within 5-ht vs. sert-positive axons in various regions of the mouse forebrain, including the prefrontal cortex, nucleus accumbens core and shell, bed nucleus of the stria terminalis, dorsal striatum, lateral septum, basolateral and central amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |