| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Randriely Merscher Sobreira de Lima, Martielo Januario da Mata, Josefa Cristina Pereira Dos Santos, Ludhielle Costa, Victor Hugo Moreira Marques, Lucas Victor Dos Santos Bento, Marcelo di Marcello Valladão Lugon, Danusa Mar Arcego, Valério Garrone Barauna, Athelson Stefanon Bittencourt, Ana Paula Santana de Vasconcellos Bittencour. Exploring the Role of Environmental Enrichment and Early Life Adversity on Emotional Development. Behavioural brain research. 2024-07-19. PMID:39029628. |
we also measured the levels of serotonin in the amygdala and dorsal raphe nucleus. |
2024-07-19 |
2024-07-22 |
rat |
| Ester Orav, Bojana Kokinovic, Heidi Teppola, Mari Siimon, Sari E Lauri, Henrike Hartun. Arginine vasopressin activates serotonergic neurons in the dorsal raphe nucleus during neonatal development in vitro and in vivo. Neuropharmacology. 2024-07-12. PMID:38996832. |
here we tested the effect of avp on the dorsal raphe nucleus (drn) 5-hydroxytryptamine (5-ht, serotonin) system in male and female neonatal rats, since early 5-ht homeostasis is critical for the development of cortical brain regions and emotional behaviors. |
2024-07-12 |
2024-07-15 |
rat |
| Fiona Henderson, Sylvie Dumas, Giuseppe Gangarossa, Véronique Bernard, Marine Pujol, Odile Poirel, Nicolas Pietrancosta, Salah El Mestikawy, Stéphanie Daumas, Véronique Fabr. Regulation of stress-induced sleep perturbations by dorsal raphe VGLUT3 neurons in male mice. Cell reports. vol 43. issue 7. 2024-06-30. PMID:38944834. |
exposure to stressors has profound effects on sleep that have been linked to serotonin (5-ht) neurons of the dorsal raphe nucleus (dr). |
2024-06-30 |
2024-07-03 |
mouse |
| Hailan Liu, Na Qu, Natalia Valdez Gonzalez, Marco A Palma, Huamin Chen, Jiani Xiong, Abhinav Choubey, Yongxiang Li, Xin Li, Meng Yu, Hesong Liu, Longlong Tu, Nan Zhang, Na Yin, Kristine Marie Conde, Mengjie Wang, Jonathan Carter Bean, Junying Han, Nikolas Anthony Scarcelli, Yongjie Yang, Kenji Saito, Huxing Cui, Qingchun Tong, Zheng Sun, Chunmei Wang, Xing Cai, Li Lu, Yang He, Yong X. A light-responsive neural circuit suppresses feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897723. |
we further show that lateral habenula (lhb) neurons in mice respond to light exposure, which in turn activates 5-ht neurons in the dorsal raphe nucleus (drn). |
2024-06-19 |
2024-06-22 |
mouse |
| Rémi Janet, Edmund Derrington, Jean-Claude Drehe. Relationships between Serotonin Transporter Availability and the Global Efficiency of the Executive Control Brain Network. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891901. |
here, we used a simultaneous pet-fmri scanner combined with graph theory analyses to investigate the modulation of network properties by the serotonin transporter (sert) availability measured in the dorsal raphe nucleus (drn). |
2024-06-19 |
2024-06-21 |
Not clear |
| Ting Sun, Ya-Ya Du, Yong-Qiang Zhang, Qin-Qin Tian, Xi Li, Jiao-Yan Yu, Yan-Yan Guo, Qing-Qing Liu, Le Yang, Yu-Mei Wu, Qi Yang, Ming-Gao Zha. Activation of GPR55 Ameliorates Maternal Separation-Induced Learning and Memory Deficits by Augmenting 5-HT Synthesis in the Dorsal Raphe Nucleus of Juvenile Mice. ACS omega. vol 9. issue 20. 2024-05-27. PMID:38799363. |
activation of gpr55 ameliorates maternal separation-induced learning and memory deficits by augmenting 5-ht synthesis in the dorsal raphe nucleus of juvenile mice. |
2024-05-27 |
2024-05-31 |
mouse |
| Ting Sun, Ya-Ya Du, Yong-Qiang Zhang, Qin-Qin Tian, Xi Li, Jiao-Yan Yu, Yan-Yan Guo, Qing-Qing Liu, Le Yang, Yu-Mei Wu, Qi Yang, Ming-Gao Zha. Activation of GPR55 Ameliorates Maternal Separation-Induced Learning and Memory Deficits by Augmenting 5-HT Synthesis in the Dorsal Raphe Nucleus of Juvenile Mice. ACS omega. vol 9. issue 20. 2024-05-27. PMID:38799363. |
although the novel cannabinoid receptor, gpr55, is recognized for its influence on learning and memory, its implications on the function and synaptic dynamics of 5-ht neurons within the dorsal raphe nucleus (drn) remain to be elucidated. |
2024-05-27 |
2024-05-31 |
mouse |
| Matti Bock Guldager, Caroline Biojone, Nicole Rodrigues da Silva, Livea Dornela Godoy, Sâmia Joc. New insights into the involvement of serotonin and BDNF-TrkB signalling in cannabidiol's antidepressant effect. Progress in neuro-psychopharmacology & biological psychiatry. vol 133. 2024-05-25. PMID:38762160. |
it is hypothesized that: a) cbd interaction with serotonin receptors on neurons of the dorsal raphe nuclei and the resulting disinhibition of serotonergic neurons would promote rapid serotonin release in the pfc and hence its neuroplastic and antidepressant effects; b) cbd facilitates bdnf-trkb signalling, especially in the pfc, which rapidly triggers neurochemical and neuroplastic effects. |
2024-05-25 |
2024-05-27 |
Not clear |
| Povilas Karvelis, Andreea O Diaconesc. A Computational Model of Hopelessness and Active-Escape Bias in Suicidality. Computational psychiatry (Cambridge, Mass.). vol 6. issue 1. 2024-05-23. PMID:38774778. |
these proposals stem from considering the neurocircuits implicated in stb: how the locus coeruleus - norepinephrine (lc-ne) system together with the amygdala (amy), the dorsal prefrontal cortex (dpfc) and the anterior cingulate cortex (acc) mediate learning in response to acute stress and volatility as well as how the dorsal raphe nucleus - serotonin (drn-5-ht) system together with the ventromedial prefrontal cortex (vmpfc) mediate stress reactivity based on perceived stressor controllability. |
2024-05-23 |
2024-05-27 |
Not clear |
| Kristine M Conde, HueyZhong Wong, Shuzheng Fang, Yongxiang Li, Meng Yu, Yue Deng, Qingzhuo Liu, Xing Fang, Mengjie Wang, Yuhan Shi, Olivia Z Ginnard, Yuxue Yang, Longlong Tu, Hesong Liu, Hailan Liu, Na Yin, Jonathan C Bean, Junying Han, Megan E Burt, Sanika V Jossy, Yongjie Yang, Qingchun Tong, Benjamin R Arenkiel, Chunmei Wang, Yang He, Yong X. 5-HT Neurons Integrate GABA and Dopamine Inputs to Regulate Meal Initiation. bioRxiv : the preprint server for biology. 2024-05-22. PMID:38746314. |
serotonin (5-ht) is one major neurotransmitter which remains an excellent target for new weight-loss therapies, but there remains a gap in knowledge on the mechanisms involved in 5-ht produced in the dorsal raphe nucleus (drn) and its involvement in meal initiation. |
2024-05-22 |
2024-05-27 |
Not clear |
| Maurizio S Riga, Mercedes Pérez-Fernández, Lluis Miquel-Rio, Verónica Paz, Leticia Campa, Magdalena Martínez-Losa, Francisco J Esteban, Luis F Callado, Javier Meana, Francesc Artigas, Analía Bortolozzi, Manuel Álvarez-Dolad. Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype. Brain : a journal of neurology. 2024-05-20. PMID:38769595. |
additionally, it reduced extracellular serotonin concentration in the dorsal raphe nucleus and brain-derived neurotrophic factor expression in the hippocampus, two mdd-related brain areas beyond the pfc. |
2024-05-20 |
2024-05-27 |
mouse |
| Wei Zhang, Ying Jin, Fu-Ming Zho. Chronic fluoxetine treatment desensitizes serotoninergic inhibition of GABA inputs and the intrinsic excitability of dorsal raphe serotonin neurons. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766100. |
chronic fluoxetine treatment desensitizes serotoninergic inhibition of gaba inputs and the intrinsic excitability of dorsal raphe serotonin neurons. |
2024-05-20 |
2024-05-27 |
Not clear |
| Wei Zhang, Ying Jin, Fu-Ming Zho. Chronic fluoxetine treatment desensitizes serotoninergic inhibition of GABA inputs and the intrinsic excitability of dorsal raphe serotonin neurons. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766100. |
dorsal raphe serotonin (5-hydroxytryptamine, 5-ht) neurons are spontaneously active and release 5-ht that is critical to normal brain function such mood and emotion. |
2024-05-20 |
2024-05-27 |
Not clear |
| Hiro Taiyo Hamada, Yoshifumi Abe, Norio Takata, Masakazu Taira, Kenji F Tanaka, Kenji Doy. Optogenetic activation of dorsal raphe serotonin neurons induces brain-wide activation. Nature communications. vol 15. issue 1. 2024-05-16. PMID:38755120. |
optogenetic activation of dorsal raphe serotonin neurons induces brain-wide activation. |
2024-05-16 |
2024-05-27 |
mouse |
| Hiro Taiyo Hamada, Yoshifumi Abe, Norio Takata, Masakazu Taira, Kenji F Tanaka, Kenji Doy. Optogenetic activation of dorsal raphe serotonin neurons induces brain-wide activation. Nature communications. vol 15. issue 1. 2024-05-16. PMID:38755120. |
here we measured brain-wide responses to optogenetic stimulation of serotonin neurons in the dorsal raphe nucleus (drn) of the male mouse brain using functional mri with an 11.7 t scanner and a cryoprobe. |
2024-05-16 |
2024-05-27 |
mouse |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. |
2024-04-08 |
2024-04-11 |
rat |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Amy S Kohtz, Joshua Zhao, Gary Aston-Jone. Serotonin signaling in hippocampus during initial cocaine abstinence drives persistent drug seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-21. PMID:38514181. |
we hypothesized that the experience of ed1 can substantially influence later relapse behavior, and that dorsal raphe serotonin (dr 5-ht) input to ca1 may be involved. |
2024-03-21 |
2024-03-24 |
rat |
| Alexandra N Petrucci, Allysa R Jones, Benjamin L Kreitlow, Gordon F Buchana. Peri-ictal activation of dorsomedial dorsal raphe serotonin neurons reduces mortality associated with maximal electroshock seizures. Brain communications. vol 6. issue 2. 2024-03-15. PMID:38487550. |
peri-ictal activation of dorsomedial dorsal raphe serotonin neurons reduces mortality associated with maximal electroshock seizures. |
2024-03-15 |
2024-03-17 |
Not clear |
| Alexandra N Petrucci, Allysa R Jones, Benjamin L Kreitlow, Gordon F Buchana. Peri-ictal activation of dorsomedial dorsal raphe serotonin neurons reduces mortality associated with maximal electroshock seizures. Brain communications. vol 6. issue 2. 2024-03-15. PMID:38487550. |
we hypothesized that optogenetic activation of dorsomedial dorsal raphe serotonin neurons in |
2024-03-15 |
2024-03-17 |
Not clear |