| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomonori Hoshino, Hajime Takase, Hidehiro Ishikawa, Gen Hamanaka, Shintaro Kimura, Norito Fukuda, Ji Hyun Park, Hiroki Nakajima, Hisashi Shirakawa, Akihiro Shindo, Kyu-Won Kim, Irwin H Gelman, Josephine Lok, Ken Ara. Transcriptomic Profiles of AKAP12 Deficiency in Mouse Corpus Callosum. Bioinformatics and biology insights. vol 18. 2024-09-30. PMID:39345723. |
although its expression level in the corpus callosum is higher than in other brain regions, such as the cerebral cortex, the role of akap12 in the corpus callosum remains unclear. |
2024-09-30 |
2024-10-02 |
mouse |
| Andrew Pearson, Milica Koprivica, Max Eisenbaum, Camila Ortiz, Mackenzie Browning, Tessa Vincennie, Cooper Tinsley, Michael Mullan, Fiona Crawford, Joseph Oj. PPARγ activation ameliorates cognitive impairment and chronic microglial activation in the aftermath of r-mTBI. Journal of neuroinflammation. vol 21. issue 1. 2024-08-03. PMID:39097742. |
we revealed that pioglitazone treatment attenuated spatial learning and memory impairments at 6 months post-injury and reduced the expression of reactive microglia and astrocyte markers in the cortex, hippocampus, and corpus callosum. |
2024-08-03 |
2024-08-06 |
mouse |
| Olga Bakina, Thomas Conrad, Nina Mitic, Ramon Oliveira Vidal, Tessa Obrusnik, Somesh Sai, Christiane Nolte, Marcus Semtner, Helmut Kettenman. In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990806. |
on average, 4138 genes were detected in 113 cells from hippocampus, corpus callosum and cortex, including microglia markers such as tmem119, p2ry12 and siglec-h. |
2024-07-11 |
2024-07-14 |
mouse |
| Yi-Ting Zhou, Da-Dao An, Yi-Xin Xu, Ying Zhou, Qing-Qing Li, Hai-Bin Dai, Xiang-Nan Zhang, Yi Wang, Min Lou, Zhong Chen, Wei-Wei H. Activation of glutamatergic neurons in the somatosensory cortex promotes remyelination in ischemic vascular dementia. Fundamental research. vol 4. issue 1. 2024-06-27. PMID:38933843. |
in a mouse model, optogenetic activation of glutamatergic neurons in the somatosensory cortex significantly promoted oligodendrocyte progenitor cell (opc) proliferation, remyelination in the corpus callosum, and recovery of cognitive ability after cerebral hypoperfusion. |
2024-06-27 |
2024-06-29 |
mouse |
| Catelynn C Shafer, Jacopo Di Lucente, Ulises Ruiz Mendiola, Izumi Maezawa, Lee-Way Jin, Elizabeth K Neuman. Effects of Sex and Western Diet on Spatial Lipidomic Profiles for the Hippocampus, Cortex, and Corpus Callosum in Mice Using MALDI MSI. Journal of the American Society for Mass Spectrometry. 2024-03-08. PMID:38456419. |
effects of sex and western diet on spatial lipidomic profiles for the hippocampus, cortex, and corpus callosum in mice using maldi msi. |
2024-03-08 |
2024-03-10 |
mouse |
| Camille Giacometti, Delphine Autran-Clavagnier, Audrey Dureux, Laura Viñales, Franck Lamberton, Emmanuel Procyk, Charles R E Wilson, Céline Amiez, Fadila Hadj-Bouzian. Differential functional organization of amygdala-medial prefrontal cortex networks in macaque and human. Communications biology. vol 7. issue 1. 2024-03-05. PMID:38443489. |
in humans, the amg-mpfc fc displays u-shaped pattern along the corpus callosum: a positive fc with the ventromedial prefrontal (vmpfc) and anterior cingulate cortex (acc), a negative fc with the anterior mid-cingulate cortex (mcc), and a positive fc with the posterior mcc. |
2024-03-05 |
2024-03-08 |
human |
| Nicholas Vidas-Guscic, Joëlle van Rijswijk, Johan Van Audekerke, Ben Jeurissen, Israel Nnah, Haiying Tang, Ignacio Munoz-Sanjuan, Dorian Pustina, Roger Cachope, Annemie Van der Linden, Daniele Bertoglio, Marleen Verhoy. Diffusion MRI marks progressive alterations in fiber integrity in the zQ175DN mouse model of Huntington's disease. Neurobiology of disease. 2024-02-16. PMID:38365045. |
we compared findings from traditional diffusion tensor imaging (dti) and advanced fixel-based analysis (fba) diffusion metrics for their sensitivity in detecting white matter anomalies in the striatum, motor cortex, and segments of the corpus callosum. |
2024-02-16 |
2024-02-19 |
mouse |
| Sukanya G Gakare, Jay M Bhatt, Kishore Kumar S Narasimhan, Shashank M Dravi. Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions. PloS one. vol 18. issue 11. 2023-11-24. PMID:37983226. |
importantly, we found that the ablation of glud1 led to an increase in the number of myelin-associated glycoprotein (mag+) cells in the corpus callosum and motor cortex at p40 without affecting the number of ng2+ opcs, suggesting that glud1 loss selectively facilitates opc differentiation rather than proliferation. |
2023-11-24 |
2023-11-28 |
mouse |
| Sukanya G Gakare, Jay M Bhatt, Kishore Kumar S Narasimhan, Shashank M Dravi. Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions. PloS one. vol 18. issue 11. 2023-11-24. PMID:37983226. |
further, deletion of glud1 enhanced myelination in the corpus callosum and motor cortex, as indicated by increased myelin basic protein (mbp) staining at p40, suggesting that glud1 may play an essential role in the developmental regulation of myelination during the critical window period. |
2023-11-24 |
2023-11-28 |
mouse |
| Megan L Ratz-Mitchem, Greg Leary, Andrea Grindeland, Derek Silvius, Joseph Guter, Michael P Kavanaugh, Teresa M Gun. Generation and characterization of a knock-in mouse model for spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM). Mammalian genome : official journal of the International Mammalian Genome Society. 2023-08-29. PMID:37642681. |
homozygous mutants had increased d-serine uptake in the brain, microcephaly, and thin corpus callosum and cortex layer 1. |
2023-08-29 |
2023-09-07 |
mouse |
| Ilja Jelisejevs, Jolanta Upite, Shivan Kalnins, Baiba Janson. An Improved Surgical Approach for Complete Interhemispheric Corpus Callosotomy Combined with Extended Frontoparietal Craniotomy in Mice. Biomedicines. vol 11. issue 7. 2023-07-29. PMID:37509422. |
to date, there exist two main approaches for transecting the corpus callosum (cc) in rodents: trephine hole(s) or unilateral craniotomy, which cause damage to the cerebral cortex or the injury of large vessels, and may lead to intracranial hemorrhage and animal death. |
2023-07-29 |
2023-08-14 |
mouse |
| Lana Frankle, Amanda Riley, Riely Tomor, Hannah Lee, Kole Jarzembak, Olesia Benedict, Sarah Sternbach, John Shelestak, Jennifer McDonough, Robert Clement. Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment. bioRxiv : the preprint server for biology. 2023-05-03. PMID:37131767. |
the authors found increases in proteins associated with both cell types at different timepoints, with protein increases in the a1 marker c3d and the a2 marker emp1 in the cortex at one week and protein increases in emp1 in the corpus callosum at three days and four weeks. |
2023-05-03 |
2023-08-14 |
Not clear |
| Lana Frankle, Amanda Riley, Riely Tomor, Hannah Lee, Kole Jarzembak, Olesia Benedict, Sarah Sternbach, John Shelestak, Jennifer McDonough, Robert Clement. Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment. bioRxiv : the preprint server for biology. 2023-05-03. PMID:37131767. |
there were also increases in emp1 staining specifically colocalized with astrocyte staining in the corpus callosum at the same timepoints as the protein increases, and in the cortex weeks later at four weeks. |
2023-05-03 |
2023-08-14 |
Not clear |
| Joseph F Bohlen, Colin M Cleary, Debamitra Das, Srinidhi Rao Sripathy, Norah Sadowski, Gina Shim, Rakaia F Kenney, Ingrid P Buchler, Tapasree Banerji, Thomas S Scanlan, Daniel K Mulkey, Brady J Mahe. Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt-Hopkins syndrome. Brain : a journal of neurology. 2023-04-17. PMID:37068912. |
in vivo, 2-week intraperitoneal administration of clemastine also normalized oligodendrocyte precursor cell and oligodendrocyte density in the cortex of tcf4 mutant mice and appeared to increase the number of axons undergoing myelination, as em imaging of the corpus callosum showed a significant increase in the proportion of uncompacted myelin and an overall reduction in the g-ratio. |
2023-04-17 |
2023-08-14 |
mouse |
| Fatih Mete, Signem Eyuboglu, Ayca Vitrinel, Ulkan Kilic, Cihan Suleyman Erdogan, Ertugrul Kilic, Bayram Yilma. Hyperthermia alters neurobehavior by affecting cell proliferation and neuronal survival in young male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2023-04-08. PMID:37029601. |
neuronal survival, apoptosis, and cell proliferation were investigated in cortex, hippocampal dentate gyrus (dg) and ca1 regions, and corpus callosum (cc). |
2023-04-08 |
2023-08-14 |
rat |
| Kelly M Flounlacker, Yun Kyung Hahn, Ruqiang Xu, Chloe A Simons, Tao Tian, Kurt F Hauser, Pamela E Knap. Myelin regulatory factor is a target of individual and interactive effects of HIV-1 Tat and morphine in the striatum and pre-frontal cortex. Journal of neurovirology. 2023-02-28. PMID:36853588. |
western blots conducted after 6-weeks exposure in 3 brain regions (striatum, corpus callosum, pre-frontal cortex) revealed regional differences in the effect of tat and morphine on myrf levels, and on levels of myelin basic protein (mbp), whose transcription is regulated by myrf. |
2023-02-28 |
2023-08-14 |
mouse |
| Krista Lamorie-Foote, Qinghai Liu, Kristina Shkirkova, Brandon Ge, Shannon He, Todd E Morgan, Wendy J Mack, Constantinos Sioutas, Caleb E Finch, William J Mac. Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice. Journal of neuroscience research. 2022-12-04. PMID:36464774. |
npm + bcas exposure increased apoptosis, neuroinflammation, and oxidative stress in the cerebral cortex and corpus callosum. |
2022-12-04 |
2023-08-14 |
mouse |
| Li-Pao Fang, Qing Liu, Erika Meyer, Anna Welle, Wenhui Huang, Anja Scheller, Frank Kirchhoff, Xianshu Ba. A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning. Glia. 2022-10-29. PMID:36308278. |
here, we identified a subset (2%-26%) of opcs lacking olig2 in various brain regions including cortex, corpus callosum, ca1 and dentate gyrus. |
2022-10-29 |
2023-08-14 |
Not clear |
| Madeline Nicholson, Rhiannon J Wood, David G Gonsalvez, Anthony J Hannan, Jessica L Fletcher, Junhua Xiao, Simon S Murra. Remodeling of myelinated axons and oligodendrocyte differentiation is stimulated by environmental enrichment in the young adult brain. The European journal of neuroscience. 2022-10-11. PMID:36217300. |
additionally, we observed a global increase in the differentiation of opcs and pre-myelinating oligodendroglia in the corpus callosum and somatosensory cortex. |
2022-10-11 |
2023-08-14 |
mouse |
| Pâmella da Silva Beggiora, Stephanya Covas da Silva, Karine Pereira Rodrigues, Timóteo Abrantes de Lacerda Almeida, Gustavo Sampaio Botelho, Gabriel Aparecido Pinto de Moura Silva, Hélio Rubens Machado, Luiza da Silva Lope. Memantine associated with ventricular-subcutaneous shunt promotes behavioral improvement, reduces reactive astrogliosis and cell death in juvenile hydrocephalic rats. Journal of chemical neuroanatomy. 2022-09-24. PMID:36152798. |
treatment with memantine resulted in significant improvement (p<0.05) in sensorimotor development, preservation of spatial memory, reduction of astrocytic reaction in the corpus callosum, cortex, and germinal matrix. |
2022-09-24 |
2023-08-14 |
rat |