All Relations between cerebral cortex and brainstem

Publication Sentence Publish Date Extraction Date Species
Venkataramanan Srinivasan, Victoria Homer, Darren Barton, Abigail Clutterbuck-James, Siân Jenkins, Claire Potter, Kristian Brock, Ann Logan, Donna Smith, Lars Bruce, Zsuzsanna Nagy, Simon P Bac. A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990927. it is a fatal disease with specific loss of motor neurons in the spinal cord, brain stem, and motor cortex leading to progressive paralysis and usually death within five years of diagnosis. 2024-07-11 2024-07-14 Not clear
Chao Zhang, R Michael Burge. Cholinergic modulation in the vertebrate auditory pathway. Frontiers in cellular neuroscience. vol 18. 2024-07-04. PMID:38962512. in this review, we highlight what is known about cholinergic function throughout the auditory system from the ear to the cortex, but with a particular emphasis on brainstem and midbrain auditory centers. 2024-07-04 2024-07-10 Not clear
Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. 2024-07-04 2024-07-10 mouse
Jason A Chen, Aaron E L Warren, John D Rolsto. Robot-assisted deep brain stimulation of the centromedian nucleus of the thalamus for generalized epilepsy: targeting and operative video. Neurosurgical focus: Video. vol 11. issue 1. 2024-07-03. PMID:38957429. cm is highly connected to cortical and subcortical regions including frontoparietal/sensorimotor cortex, striatum, brainstem, and cerebellum, which are involved in some generalized epilepsy syndromes like lennox-gastaut syndrome (lgs). 2024-07-03 2024-07-06 Not clear
Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. 2024-06-20 2024-06-23 Not clear
Xóchitl Andrea Mendiola-Salazar, Melanie A Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pére. SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892464. in this study, we investigated whether severe acute respiratory syndrome coronavirus-2 (sars-cov-2) spike protein may modify angiotensin-converting enzyme 2 (ace2) activity in the plasma, heart, kidney, liver, lung, and six brain regions (amygdala, brain stem, cortex, hippocampus, hypothalamus, and striatum) of diabetic and hypertensive rats. 2024-06-19 2024-06-21 rat
Xóchitl Andrea Mendiola-Salazar, Melanie A Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pére. SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892464. ace2 activity was augmented in the liver, brain stem, and striatum, while it decreased in the kidney, amygdala, cortex, and hippocampus of diabetic rats. 2024-06-19 2024-06-21 rat
Xóchitl Andrea Mendiola-Salazar, Melanie A Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pére. SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892464. we measured the ace2 content via enzyme-linked immunosorbent assay and found that ace2 protein levels increased in the heart, while it decreased in the plasma, kidney, brain stem, cortex, hippocampus, hypothalamus, and striatum of diabetic rats. 2024-06-19 2024-06-21 rat
Xóchitl Andrea Mendiola-Salazar, Melanie A Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pére. SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892464. ace2 protein levels decreased in the brain stem, cortex, hippocampus, and hypothalamus of hypertensive rats. 2024-06-19 2024-06-21 rat
Neruja Loganathan, Calvin V Lieu, Denise D Belsha. Immortalization and characterization of GFAP-expressing glial cells from the adult mouse hypothalamus, cortex, and brain stem. Neuroscience. 2024-05-24. PMID:38788830. a comparative approach was taken with two other murine gfap-expressing cell lines that were also generated in this study: a mixed glial cell line from the cortex (mcorta-g1) and an oligodendrocyte cell line from the brainstem (mbsta-olig1), as well as an established microglial cell line (img). 2024-05-24 2024-05-27 mouse
Ilaria Martinelli, Jessica Mandrioli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Cecilia Simonini, Francesco Cavallieri, Franco Valzani. Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence? Neural regeneration research. vol 20. issue 1. 2024-05-20. PMID:38767482. amyotrophic lateral sclerosis (als) is a neuromuscular condition resulting from the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. 2024-05-20 2024-05-27 human
Sharon Natasha Cox, Claudio Lo Giudice, Anna Lavecchia, Maria Luana Poeta, Matteo Chiara, Ernesto Picardi, Graziano Pesol. Mitochondrial and Nuclear DNA Variants in Amyotrophic Lateral Sclerosis: Enrichment in the Mitochondrial Control Region and Sirtuin Pathway Genes in Spinal Cord Tissue. Biomolecules. vol 14. issue 4. 2024-04-27. PMID:38672428. amyotrophic lateral sclerosis (als) is a progressive disease with prevalent mitochondrial dysfunctions affecting both upper and lower motor neurons in the motor cortex, brainstem, and spinal cord. 2024-04-27 2024-04-29 human
Peter J Bosch, Gemma Kerr, Rachel Cole, Charles A Warwick, Linder H Wendt, Akash Pradeep, Emma Bagnall, Georgina M Aldridg. Enhanced Spine Stability and Survival Lead to Increases in Dendritic Spine Density as an Early Response to Local Alpha-Synuclein Overexpression in Mouse Prefrontal Cortex. Cellular and molecular neurobiology. vol 44. issue 1. 2024-04-26. PMID:38668880. lewy body dementias (lbd), including parkinson's disease dementia and dementia with lewy bodies, are characterized by widespread accumulation of intracellular alpha-synuclein protein deposits in regions beyond the brainstem, including in the cortex. 2024-04-26 2024-04-28 mouse
Shiyu Fu, Zhiquan Yan. Motor cortex stimulation for the treatment of trigeminal neuralgia after brainstem infarction: A case report. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 49. issue 1. 2024-04-13. PMID:38615166. motor cortex stimulation for the treatment of trigeminal neuralgia after brainstem infarction: a case report. 2024-04-13 2024-04-16 Not clear
Jarek Wegiel, Kathryn Chadman, Eric London, Thomas Wisniewski, Jerzy Wegie. Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. 2024-03-19. PMID:38500252. this review highlights a key role of the serotonergic system in brain development and in distortions of normal brain development in early stages of fetal life resulting in cascades of abnormalities, including defects of neurogenesis, neuronal migration, neuronal growth, differentiation, and arborization, as well as defective neuronal circuit formation in the cortex, subcortical structures, brainstem, and cerebellum of autistic subjects. 2024-03-19 2024-03-21 human
LiJun Zhou, RenShi X. Invertebrate genetic models of amyotrophic lateral sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-03-19. PMID:38500677. amyotrophic lateral sclerosis (als) is a common adult-onset neurodegenerative disease characterized by the progressive death of motor neurons in the cerebral cortex, brain stem, and spinal cord. 2024-03-19 2024-03-21 human
Jelena Scekic-Zahirovic, Cristina Benetton, Aurore Brunet, XiaoQian Ye, Evgeny Logunov, Vincent Douchamps, Salim Megat, Virginie Andry, Vanessa Wing Yin Kan, Geoffrey Stuart-Lopez, Johan Gilet, Simon J Guillot, Sylvie Dirrig-Grosch, Charlotte Gorin, Margaux Trombini, Stéphane Dieterle, Jérôme Sinniger, Mathieu Fischer, Frédérique René, Zeynep Gunes, Pascal Kessler, Luc Dupuis, Pierre-François Pradat, Yannick Goumon, Romain Goutagny, Véronique Marchand-Pauvert, Sabine Liebscher, Caroline Rouau. Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency. Science translational medicine. vol 16. issue 738. 2024-03-13. PMID:38478631. amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease, characterized by the death of upper (umn) and lower motor neurons (lmn) in the motor cortex, brainstem, and spinal cord. 2024-03-13 2024-03-16 mouse
Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. gender-related variation expressions of neuroplastin traf6, glua1, gaba(a) receptor, and pmca in cortex, hippocampus, and brainstem in an experimental epilepsy model. 2024-03-04 2024-03-06 rat
Patrizia Ratano, Germana Cocozza, Cecilia Pinchera, Ludovica Maria Busdraghi, Iva Cantando, Katiuscia Martinello, Mariarosaria Scioli, Maria Rosito, Paola Bezzi, Sergio Fucile, Heike Wulff, Cristina Limatola, Giuseppina D'Alessandr. Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3. Frontiers in molecular neuroscience. vol 16. 2024-01-31. PMID:38292023. amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with no effective therapy, causing progressive loss of motor neurons in the spinal cord, brainstem, and motor cortex. 2024-01-31 2024-02-02 mouse
Jian Lu, An-Xu He, Zhuo-Ying Jin, Meng Zhang, Zhong-Xin Li, Fan Zhou, Lin Ma, Hong-Ming Jin, Jia-Ying Wang, Xu She. Desloratadine alleviates ALS-like pathology in hSOD1 Acta pharmacologica Sinica. 2024-01-29. PMID:38286832. desloratadine alleviates als-like pathology in hsod1 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with progressive loss of motor neurons in the spinal cord, cerebral cortex and brain stem. 2024-01-29 2024-02-01 Not clear