| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alejandro Dorado, Juan Lorenzo Terrasa, Marian van der Meulen, Pedro Montoya, Ana María González-Roldá. Altered endogenous pain inhibitory function in older adults with chronic pain is associated with disruptions in functional connectivity during resting state. The journal of pain. 2024-07-19. PMID:39029880. |
rsfc analysis showed that older adults with chronic pain, in comparison to younger participants, displayed an abnormal hyperconnectivity between right dorsolateral prefrontal cortex (dlpfc) and left amygdala (amy), which was significantly correlated with lower pain inhibition during the cpm. |
2024-07-19 |
2024-07-22 |
human |
| Spencer B Huggett, Sharmila Selveraj, John E McGeary, Ami Ikeda, Emerald Yuan, Lauren B Loeffel, Rohan H C Palme. Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use. bioRxiv : the preprint server for biology. 2024-07-15. PMID:39005451. |
this study explores the neurobiological underpinnings of alcohol use disorder (aud) by integrating bulk and single-cell transcriptomic data from humans, primates, and mice across three brain regions associated with addiction (i.e., prefrontal cortex (pfc), nucleus accumbens (nac), and central amygdala (cea)). |
2024-07-15 |
2024-07-18 |
mouse |
| Toshinori Yoshioka, Akiyoshi Saito. [Underlying mechanisms for psychotropic effects of delta opioid receptor agonists]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 159. issue 4. 2024-06-30. PMID:38945905. |
in rodent studies, we have also demonstrated that dop agonists exhibit potent anxiolytic-like effects via the inhibition of the excitatory neuronal activity which projects to the amygdala from the prelimbic prefrontal cortex and facilitate extinction learning of contextual fear memory through pi3k-akt signaling pathway in the infralimbic prefrontal cortex and mek-erk signaling pathway in the amygdala. |
2024-06-30 |
2024-07-03 |
mouse |
| Noemi Nicosia, Mattia Giovenzana, Paulina Misztak, Jessica Mingardi, Laura Musazz. Glutamate-Mediated Excitotoxicity in the Pathogenesis and Treatment of Neurodevelopmental and Adult Mental Disorders. International journal of molecular sciences. vol 25. issue 12. 2024-06-27. PMID:38928227. |
indeed, brain areas involved in memory formation and consolidation as well as in fear and emotional processing, such as the hippocampus, prefrontal cortex, and amygdala, are predominantly glutamatergic. |
2024-06-27 |
2024-06-29 |
Not clear |
| Nian-Sheng Tzeng, Jing-Yi Chung, Chen-Cheng Lin, Pao-Yun Cheng, Yia-Ping Li. Effects of Subchronic Buspirone Treatment on Depressive Profile in Socially Isolated Rats: Implication of Early Life Experience on 5-HT1A Receptor-Related Depression. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931384. |
tissue levels of serotonin (5-ht) and its metabolite 5-hiaa were measured in the hippocampus, the amygdala, and the prefrontal cortex. |
2024-06-27 |
2024-06-29 |
rat |
| Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |
| Caitlyn R Cody, Emilce Artur de la Villarmois, Anabel Miguelez Fernandez, Janelle Lardizabal, Chaney McKnight, Kuei Tseng, Heather C Brenhous. Effects of early life adversity and adolescent basolateral amygdala activity on corticolimbic connectivity and anxiety behaviors. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853948. |
prior work has shown that early life adversity (ela) leads to hyperinnervation of glutamatergic basolateral amygdala (bla) projections to the prefrontal cortex (pfc) in adolescence. |
2024-06-10 |
2024-06-14 |
Not clear |
| Shima Jahangiri, Mahdi Naeim, Mahboobeh Majidnia, Maryam Mostafavi, Shima Imannezhad, Yasaman Mohammad. Unveiling the neuro-cognitive paradigm: a new approach to the treatment of anxiety: a comprehensive review. Annals of medicine and surgery (2012). vol 86. issue 6. 2024-06-08. PMID:38846870. |
the findings revealed the involvement of brain regions similar to the amygdala, prefrontal cortex, and hippocampus in anxiety diseases, along with dysregulation in neurotransmitter systems. |
2024-06-08 |
2024-06-10 |
Not clear |
| Isabel C Duarte, Ana Dionísio, Joana Oliveira, Marco Simões, Rita Correia, Joana A Dias, Salomé Caldeira, João Redondo, Miguel Castelo-Branc. Neural underpinnings of ethical decisions in life and death dilemmas in naïve and expert firefighters. Scientific reports. vol 14. issue 1. 2024-06-08. PMID:38851794. |
these realistic life-saving dilemmas activate the same core reward and affective processing network, in particular the ventromedial prefrontal cortex, nucleus accumbens and amygdala, irrespective of prior expertise, thereby supporting general domain theories of ethical decision-making. |
2024-06-08 |
2024-06-11 |
Not clear |
| Anna Waisman, Joel Kat. The Autobiographical Memory System and Chronic Pain: A Neurocognitive Framework for the Initiation and Maintenance of Chronic Pain. Neuroscience and biobehavioral reviews. 2024-05-25. PMID:38796124. |
here, we 1) summarize the current literature on autobiographical memory in pain, 2) discuss the role of the hippocampus and cortical brain regions including the ventromedial prefrontal cortex, anterior temporal lobe, and amygdala in relation to autobiographical memory, memory schemas, emotional processing, and pain, 3) synthesize these findings in a neurocognitive framework that explains these relationships and their implications for patients' pain outcomes, and 4) propose translational directions for the prevention, management, and treatment of chronic pain. |
2024-05-28 |
2024-06-03 |
Not clear |
| Anna Waisman, Joel Kat. The Autobiographical Memory System and Chronic Pain: A Neurocognitive Framework for the Initiation and Maintenance of Chronic Pain. Neuroscience and biobehavioral reviews. 2024-05-25. PMID:38796124. |
here, we 1) summarize the current literature on autobiographical memory in pain, 2) discuss the role of the hippocampus and cortical brain regions including the ventromedial prefrontal cortex, anterior temporal lobe, and amygdala in relation to autobiographical memory, memory schemas, emotional processing, and pain, 3) synthesize these findings in a neurocognitive framework that explains these relationships and their implications for patients' pain outcomes, and 4) propose translational directions for the prevention, management, and treatment of chronic pain. |
2024-05-25 |
2024-06-03 |
Not clear |
| Povilas Karvelis, Andreea O Diaconesc. A Computational Model of Hopelessness and Active-Escape Bias in Suicidality. Computational psychiatry (Cambridge, Mass.). vol 6. issue 1. 2024-05-23. PMID:38774778. |
these proposals stem from considering the neurocircuits implicated in stb: how the locus coeruleus - norepinephrine (lc-ne) system together with the amygdala (amy), the dorsal prefrontal cortex (dpfc) and the anterior cingulate cortex (acc) mediate learning in response to acute stress and volatility as well as how the dorsal raphe nucleus - serotonin (drn-5-ht) system together with the ventromedial prefrontal cortex (vmpfc) mediate stress reactivity based on perceived stressor controllability. |
2024-05-23 |
2024-05-27 |
Not clear |
| Man Han, Deyang Zeng, Wei Tan, Xingxing Chen, Shuyuan Bai, Qiong Wu, Yushan Chen, Zhen Wei, Yufei Mei, Yan Zen. Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior. Neural regeneration research. vol 20. issue 1. 2024-05-20. PMID:38767484. |
recent studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region-specific, particularly involving the corticolimbic system, including the ventral tegmental area, nucleus accumbens, prefrontal cortex, amygdala, and hippocampus. |
2024-05-20 |
2024-05-27 |
mouse |
| Carmen Morawetz, Ulrike Baste. Neural underpinnings of individual differences in emotion regulation: A systematic review. Neuroscience and biobehavioral reviews. 2024-05-17. PMID:38759742. |
in showing that individual differences in regulation success and er-related traits can be traced back to differences in the neural activity of brain regions associated with emotional reactivity (amygdala) and cognitive control (lateral prefrontal cortex), our findings can inform prospective personalised intervention models. |
2024-05-17 |
2024-05-27 |
Not clear |
| Ralph J Koek, Josue Avecillas-Chasin, Scott E Krahl, James Wy Chen, David L Sultzer, Alexis D Kulick, Mark A Mandelkern, Maura Malpetti, Hailey L Gordon, Holly N Landry, Evan H Einstein, Jean-Philippe Langevi. Deep brain stimulation of the amygdala for treatment-resistant combat post-traumatic stress disorder: Long-term results. Journal of psychiatric research. vol 175. 2024-05-11. PMID:38733927. |
reminder-triggered symptoms may arise from inadequate top-down ventromedial prefrontal cortex (vmpfc) control of amygdala reactivity. |
2024-05-11 |
2024-05-27 |
human |
| Giulia Poggi, Federica Klaus, Christopher R Pryc. Pathophysiology in cortico-amygdala circuits and excessive aversion processing: the role of oligodendrocytes and myelination. Brain communications. vol 6. issue 3. 2024-05-08. PMID:38712320. |
here, we assess the comparative evidence for: (i) anterior cingulate/medial prefrontal cortex<->amygdala bidirectional neural circuits as major contributors to aversive stimulus processing; (ii) structural and functional changes in anterior cingulate cortex<->amygdala circuit associated with excessive aversion processing in stress-related neuropsychiatric disorders, and in medial prefrontal cortex<->amygdala circuit in rodent models of chronic stress-induced increased aversion reactivity; and (iii) altered status of oligodendrocytes and their oligodendrocyte lineage cells and myelination in anterior cingulate/medial prefrontal cortex<->amygdala circuits in stress-related neuropsychiatric disorders and stress models. |
2024-05-08 |
2024-05-27 |
human |
| Giulia Poggi, Federica Klaus, Christopher R Pryc. Pathophysiology in cortico-amygdala circuits and excessive aversion processing: the role of oligodendrocytes and myelination. Brain communications. vol 6. issue 3. 2024-05-08. PMID:38712320. |
the comparative evidence from humans and rodents is that their respective anterior cingulate/medial prefrontal cortex<->amygdala circuits are integral to adaptive aversion processing. |
2024-05-08 |
2024-05-27 |
human |
| Linfeng Hu, Catherine Stamouli. Strength and resilience of developing brain circuits predict adolescent emotional and stress responses during the COVID-19 pandemic. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 4. 2024-04-26. PMID:38669008. |
lower connectivity of left salience, reward, limbic, and prefrontal cortex and its thalamic, striatal, amygdala connections, predicted higher stress (β = -0.46 to -0.20, ci = [-0.72, -0.07], p < 0.03). |
2024-04-26 |
2024-04-28 |
Not clear |
| Yehong Fang, Yunkai Sun, Yi Liu, Tieqiao Liu, Wei Hao, Yanhui Lia. Neurobiological mechanisms and related clinical treatment of addiction: a review. Psychoradiology. vol 2. issue 4. 2024-04-26. PMID:38665277. |
the changes in the orbitofrontal cortex, dorsolateral prefrontal cortex, amygdala, and hypothalamus emotional system in the withdrawal/negative affect stage involve increases in negative emotional states, dysphoric-like effects, and stress-like responses. |
2024-04-26 |
2024-04-28 |
Not clear |
| Sagarika Jaiswal, Lakshman N C Chakravarthula, Srikanth Padmal. Additive Effects of Monetary Loss and Positive Emotion in the Human Brain. eNeuro. vol 11. issue 4. 2024-04-17. PMID:38565297. |
we found overlapping main effects of positive (vs neutral) emotion and loss (vs no loss) in multiple brain regions, including the ventromedial prefrontal cortex, striatum, and amygdala, notably with a lack of evidence for interaction. |
2024-04-17 |
2024-04-20 |
human |