| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |
| Simin Deng, Si Tan, Cuihua Guo, Yanxiong Liu, Xiuhong L. Impaired effective functional connectivity in the social preference of children with autism spectrum disorder. Frontiers in neuroscience. vol 18. 2024-06-14. PMID:38872942. |
the medial prefrontal cortex (mpfc), amygdala (amyg), and nucleus accumbens (nac) have been identified as critical players in the social preference of individuals with asd. |
2024-06-14 |
2024-06-16 |
Not clear |
| Pan Xu, Gyeongah Park, Xiaoqian Sun, Qian Ge, Zhen Jin, Chien-Hsien Lai, Xiaojie Liu, Qingsong Liu, Rahul Simha, Chen Zeng, Jianyang Du, Hui L. Different emotional states engage distinct descending pathways from the prefrontal cortex. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853906. |
using in vivo calcium imaging, electrophysiology, and optogenetics, we examined neural circuit dynamics in the medial prefrontal cortex (mpfc), targeting two key areas: the basal lateral amygdala (bla) and nucleus accumbens (nac). |
2024-06-10 |
2024-06-14 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
zl006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. |
2024-06-08 |
2024-06-11 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
in this study, we employed a robust viral tracing technique to identify the alteration of the neural pathway connecting the medial prefrontal cortex to the basolateral amygdala, and we observed the disruptions in neuronal projections between the medial prefrontal cortex and the basolateral amygdala following closed head injury. |
2024-06-08 |
2024-06-11 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
specifically, zl006 effectively mitigates the disruptions in neuronal projections from the medial prefrontal cortex to basolateral amygdala induced by closed head injury. |
2024-06-08 |
2024-06-11 |
Not clear |
| Diana Chan, Kathryn D Baker, Rick Richardso. The impact of chronic fluoxetine treatment in adolescence or adulthood on context fear memory and perineuronal nets. Developmental psychobiology. vol 66. issue 5. 2024-05-29. PMID:38807259. |
here, we investigated the effect of fluoxetine exposure during adolescence or adulthood on context fear memory and pnns in the basolateral amygdala (bla), the ca1 subregion of the hippocampus, and the medial prefrontal cortex in rats. |
2024-05-29 |
2024-06-03 |
rat |
| Giulia Poggi, Federica Klaus, Christopher R Pryc. Pathophysiology in cortico-amygdala circuits and excessive aversion processing: the role of oligodendrocytes and myelination. Brain communications. vol 6. issue 3. 2024-05-08. PMID:38712320. |
here, we assess the comparative evidence for: (i) anterior cingulate/medial prefrontal cortex<->amygdala bidirectional neural circuits as major contributors to aversive stimulus processing; (ii) structural and functional changes in anterior cingulate cortex<->amygdala circuit associated with excessive aversion processing in stress-related neuropsychiatric disorders, and in medial prefrontal cortex<->amygdala circuit in rodent models of chronic stress-induced increased aversion reactivity; and (iii) altered status of oligodendrocytes and their oligodendrocyte lineage cells and myelination in anterior cingulate/medial prefrontal cortex<->amygdala circuits in stress-related neuropsychiatric disorders and stress models. |
2024-05-08 |
2024-05-27 |
human |
| Yi Chen, Ye Ma, Xiaoli Fan, Jiamin Lyu, Rongwang Yan. Facial expression recognition ability and its neuropsychological mechanisms in children with attention deficit and hyperactive disorder. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 2024-04-23. PMID:38650447. |
the neuropsychological mechanisms underlying these difficulties are as follows: 1. neuroanatomically, compared to typically developing children, children with adhd show smaller gray matter volume and surface area in the amygdala and medial prefrontal cortex regions, as well as reduced density and volume of axons/cells in certain frontal white matter fiber tracts; 2. neurophysiologically, children with adhd exhibit increased slow-wave activity in their electroencephalogram, and event-related potential studies reveal abnormalities in emotional regulation and responses to angry faces when facing facial stimuli; 3. psychologically, psychosocial stressors may influence fer abilities in children with adhd, and sleep deprivation in adhd children may significantly increase their recognition threshold for negative expressions such as sadness and anger. |
2024-04-23 |
2024-04-26 |
Not clear |
| Huihui Tan, Chengxue Du, Li Zhang, Yuan Guo, Yaxin Yang, Qingfeng Sun, Qiaojun Zhang, Libo L. Lesions of the lateral habenula excite dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nuclei in hemiparkinsonian rats. Brain research. 2024-04-08. PMID:38588847. |
the lateral habenula (lhb) projects to the ventral tegmental area (vta) and dorsal raphe nuclei (drn) that deliver dopamine (da) and serotonin (5-ht) to cortical and limbic regions such as the medial prefrontal cortex (mpfc), hippocampus and basolateral amygdala (bla). |
2024-04-08 |
2024-04-11 |
rat |
| Thays Brenner Santos, Cesar Augusto de Oliveira Coelho, Juliana Carlota Kramer-Soares, Paul W Frankland, Maria Gabriela Menezes Oliveir. Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-07. PMID:38454052. |
we used robust activity marking (ram) to selectively manipulate pl neurons activated by cfc-5s learning and targeted recombination in active populations (trap2) mice to label neurons activated by cfc-5s learning and reactivated by memory retrieval in the amygdala, medial prefrontal cortex, hippocampus, perirhinal cortices (per) and subiculum. |
2024-03-07 |
2024-03-10 |
mouse |
| Bao-Zhu Yang, Bo Xiang, Tingting Wang, Shuangge Ma, Chiang-Shan R L. Neurogenetic underpinnings of nicotine use severity: Integrating the brain transcriptomes and GWAS variants via network approaches. Psychiatry research. vol 334. 2024-02-29. PMID:38422867. |
eight brain-region-specific coexpression subnetworks were identified in association with cpd: amygdala, hippocampus, medial prefrontal cortex (mpfc), orbitofrontal cortex (opfc), dorsolateral prefrontal cortex, striatum, mediodorsal nucleus of the thalamus (mdthal), and primary motor cortex (m1c). |
2024-02-29 |
2024-03-03 |
human |
| Sheng-Ta Tsai, Chia-Chun Yang, Hsien-Yin Liao, Yi-Wen Li. Electroacupuncture Reduces Fibromyalgia Pain via Neuronal/Microglial Inactivation and Toll-like Receptor 4 in the Mouse Brain: Precise Interpretation of Chemogenetics. Biomedicines. vol 12. issue 2. 2024-02-24. PMID:38397989. |
tlr4 and inflammatory mediator-related molecules were increased in the thalamus, medial prefrontal cortex, somatosensory cortex (ssc), and amygdala of fm mice, indicating neuroinflammation and microglial activation. |
2024-02-24 |
2024-02-26 |
mouse |
| Jia-Ya Zheng, Xue-Xin Li, Xiao Liu, Chen-Chen Zhang, Ya-Xin Sun, Yu-Nu Ma, Hong-Li Wang, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Fluoxetine reverses early-life stress-induced depressive-like behaviors and region-specific alterations of monoamine transporters in female mice. Pharmacology, biochemistry, and behavior. 2024-02-09. PMID:38336220. |
at the molecular level, we largely replicated the es effects, such as reduced serotonin transporter (sert) expression in the amygdala and increased norepinephrine transporter (net) expression in the medial prefrontal cortex (mpfc) and hippocampus. |
2024-02-09 |
2024-02-12 |
mouse |
| Youqing Cai, Jianlong Ge, Zhizhong Z Pa. The projection from dorsal medial prefrontal cortex to basolateral amygdala promotes behaviors of negative emotion in rats. Frontiers in neuroscience. vol 18. 2024-02-08. PMID:38327845. |
the projection from dorsal medial prefrontal cortex to basolateral amygdala promotes behaviors of negative emotion in rats. |
2024-02-08 |
2024-02-10 |
rat |
| Youqing Cai, Jianlong Ge, Zhizhong Z Pa. The projection from dorsal medial prefrontal cortex to basolateral amygdala promotes behaviors of negative emotion in rats. Frontiers in neuroscience. vol 18. 2024-02-08. PMID:38327845. |
brain circuits between medial prefrontal cortex (mpfc) and amygdala have been implicated in cortical control of emotion, especially anxiety. |
2024-02-08 |
2024-02-10 |
rat |
| Oguz Gozen, Buket Aypar, Meliha Ozturk Bintepe, Fulya Tuzcu, Burcu Balkan, Ersin O Koylu, Lutfiye Kanit, Aysegul Kese. Chronic Nicotine Consumption and Withdrawal Regulate Melanocortin Receptor, CRF, and CRF Receptor mRNA Levels in the Rat Brain. Brain sciences. vol 14. issue 1. 2024-01-22. PMID:38248278. |
quantitative real-time pcr analysis demonstrated that nicotine exposure (with or without withdrawal) increased levels of crf and crfr1 mrna in the amygdala, crf mrna in the medial prefrontal cortex, and crfr1 mrna in the septum. |
2024-01-22 |
2024-01-24 |
rat |
| Jayapriya Chandrasekaran, Kevin K Caldwell, Jonathan L Brigma. Dynamic regulation of corticostriatal glutamatergic synaptic expression during reversal learning in male mice. Neurobiology of learning and memory. 2024-01-19. PMID:38242226. |
following training to well-established stages of discrimination and reversal learning on a touchscreen visual task, lateral orbitofrontal cortex (ofc), dorsal striatum (ds) as well as medial prefrontal cortex (mpfc), basolateral amygdala (bla) and piriform cortex (pir) were micro dissected from male mouse brain and the expression of glutamatergic receptor subunits in the synaptic fraction were measured via immunoblotting. |
2024-01-19 |
2024-01-22 |
mouse |
| Olga V Burenkova, Oksana Yu Naumova, Jessica A Church, Jenifer Juranek, Jack M Fletcher, Elena L Grigorenk. Associations between telomere length, glucocorticoid receptor gene DNA methylation, volume of stress-related brain structures, and academic performance in middle-school-age children. Comprehensive psychoneuroendocrinology. vol 17. 2024-01-15. PMID:38223236. |
studying previously revealed and objective biomarkers of early life stress exposure, such as telomere length (tl), glucocorticoid receptor gene dna methylation (dname), and the volume of brain structures involved in the regulation of hpa axis functioning (the hippocampus, the amygdala, and the medial prefrontal cortex), in relation to academic performance is crucial. |
2024-01-15 |
2024-01-17 |
Not clear |
| Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Brain structure & function. 2024-01-09. PMID:38193917. |
novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). |
2024-01-09 |
2024-01-10 |
rat |