| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Lei, Bilin Kang, Yuejun Hao, Haoyu Yang, Zihan Zhong, Zihan Zhai, Yi Zhon. Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating. Neuron. 2024-12-17. PMID:39689709. |
such a reconstructed hippocampal memory is then integrated with the valence of remote memory via medial prefrontal cortex projection-mediated activity coordination between the hippocampus and amygdala. |
2024-12-17 |
2024-12-21 |
Not clear |
| Brittani Wallsten, Abigail H Gligor, Angela E Gonzalez, Jonathan D Ramos, Michael V Baratta, Barbara A Sor. Response of Parvalbumin interneurons and perineuronal nets in rat medial prefrontal cortex and lateral amygdala to stressor controllability. Brain research. 2024-11-26. PMID:39592089. |
response of parvalbumin interneurons and perineuronal nets in rat medial prefrontal cortex and lateral amygdala to stressor controllability. |
2024-11-26 |
2024-11-29 |
rat |
| Lexi J Hand, Louise M Paterson, Anne R Lingford-Hughe. Re-evaluating our focus in addiction: emotional dysregulation is a critical driver of relapse to drug use. Translational psychiatry. vol 14. issue 1. 2024-11-09. PMID:39521844. |
in opioid dependence, the amygdala was consistently implicated, whilst the insula, anterior cingulate, and medial prefrontal cortex were implicated in cannabis dependence. |
2024-11-09 |
2024-11-17 |
Not clear |
| Sevil Duvarc. Dopaminergic circuits controlling threat and safety learning. Trends in neurosciences. 2024-10-29. PMID:39472156. |
in this review, i highlight recent studies demonstrating that dopamine neurons generate prediction errors for threat and safety, and describe how dopamine projections to the amygdala, medial prefrontal cortex (mpfc), and striatum regulate associative threat and safety learning. |
2024-10-29 |
2024-11-02 |
Not clear |
| Yi-Wen Lin, Szu-Wei Cheng, Wen-Chun Liu, Halliru Zailani, Suet-Kei Wu, Mien-Chie Hung, Kuan-Pin S. Chemogenetic targeting TRPV1 in obesity-induced depression: Unveiling therapeutic potential of eicosapentaenoic acid and acupuncture. Brain, behavior, and immunity. 2024-10-25. PMID:39454693. |
mice fed a high-fat diet showed altered trpv1 pathway expression in brain regions of the mice: downregulated in the medial prefrontal cortex (mpfc) and hippocampus, and upregulated in the hypothalamus and amygdala, influencing depression-like behaviors and inflammation. |
2024-10-25 |
2024-10-29 |
mouse |
| Irina V Pavlova, Nadezhda D Broshevitskaya, Anastasiya A Potekhina, Anastasiya M Shvadchenk. The Effect of Chronic Overcrowding on Social Behavior and Expression of Neuroinflammation-Associated Genes in Rats. Biochemistry. Biokhimiia. vol 89. issue 9. 2024-10-17. PMID:39418517. |
after decapitation of rats on p180, amygdala, dorsal hippocampus, ventromedial hypothalamus, and medial prefrontal cortex were collected and analyzed for expression of the il-1β, tnf, tgf-β1, and il-6 mrnas by quantitative polymerase chain reaction. |
2024-10-17 |
2024-10-20 |
rat |
| Yu-Rui Liu, Chun-Hui Chan. Activation, but not inactivation, of the medial or lateral orbitofrontal cortex impaired context-specific fear encoding. Neurobiology of learning and memory. 2024-10-16. PMID:39414127. |
because of the extensive anatomical connections of the ofc with the fear circuit, including the hippocampus, the amygdala, and the medial prefrontal cortex, and the reasoning that proper retrieval of fear-related memory is context-dependent, we raised the question to investigate the ability of the animals to discriminate between contexts when they were trained under differential ofc activation levels during the encoding of contextual fear memory. |
2024-10-16 |
2024-10-19 |
rat |
| Li Wang, Ting Li, Ruolei Gu, Chunliang Fen. Large-scale meta-analyses and network analyses of neural substrates underlying human escalated aggression. NeuroImage. vol 299. 2024-09-02. PMID:39214437. |
our results revealed that brain regions constantly involved in escalated aggression were localized in the subcortical network (amygdala and lateral orbitofrontal cortex) associated with emotion processing, the default mode network (dorsal medial prefrontal cortex and middle temporal gyrus) associated with mentalizing, and the salience network (anterior cingulate cortex and anterior insula) associated with cognitive control. |
2024-09-02 |
2024-09-04 |
human |
| Jing Li, Zixuan He, Weitai Chai, Meng Tian, Huali Yu, Xiaoxiao He, Xiaojuan Zh. Dip2a regulates stress susceptibility in the basolateral amygdala. Neural regeneration research. vol 20. issue 6. 2024-08-06. PMID:39104112. |
therefore, we performed targeted neurotransmitter metabolomics analysis and found that dip2a deficiency caused abnormal metabolism of tryptophan and thyroxine in the basolateral amygdala and medial prefrontal cortex. |
2024-08-06 |
2024-08-08 |
mouse |
| Jiaquan Liang, Lei Chen, Yongbiao Li, Yuewen Chen, Lin Yuan, Yue Qiu, Shuangshuang Ma, Fangcheng Fan, Yong Chen. Unraveling the Prefrontal Cortex-Basolateral Amygdala Pathway's Role on Schizophrenia's Cognitive Impairments: A Multimodal Study in Patients and Mouse Models. Schizophrenia bulletin. vol 50. issue 4. 2024-07-28. PMID:38811350. |
this study investigated the role of the medial prefrontal cortex (mpfc)-basolateral amygdala (bla) pathway in schizophrenia (scz)-related cognitive impairments using various techniques. |
2024-07-28 |
2024-08-02 |
mouse |
| Samuel E Cooper, Augustin C Hennings, Sophia A Bibb, Jarrod A Lewis-Peacock, Joseph E Dunsmoo. Semantic structures facilitate threat memory integration throughout the medial temporal lobe and medial prefrontal cortex. Current biology : CB. 2024-07-26. PMID:39059393. |
we observed selective but transient changes in the representation of conceptually related items in the amygdala, medial prefrontal cortex, and occipitotemporal cortex following threat conditioning to a simple cue (geometric shape) pre-associated with a different, but related, set of category exemplars. |
2024-07-26 |
2024-07-29 |
Not clear |
| Samuel E Cooper, Augustin C Hennings, Sophia A Bibb, Jarrod A Lewis-Peacock, Joseph E Dunsmoo. Semantic structures facilitate threat memory integration throughout the medial temporal lobe and medial prefrontal cortex. Current biology : CB. 2024-07-26. PMID:39059393. |
reactivation of the semantic category during threat conditioning, combined with activation of the hippocampus or medial prefrontal cortex, was predictive of subsequent amygdala reactivity toward novel category members at test. |
2024-07-26 |
2024-07-29 |
Not clear |
| Caesar M Hernandez, Macy A McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L Jackson, Lynn E Dobrunz, Peter H King, Lori L McMaho. In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat. Brain, behavior, & immunity - health. vol 39. 2024-07-18. PMID:39022628. |
we also assessed whether markers of inflammation or ad-like pathology in the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), basolateral amygdala (bla), or nucleus accumbens (nac), all structures that directly support the aforementioned behaviors, were predictive of behavioral deficits. |
2024-07-18 |
2024-07-20 |
rat |
| Simin Deng, Si Tan, Cuihua Guo, Yanxiong Liu, Xiuhong L. Impaired effective functional connectivity in the social preference of children with autism spectrum disorder. Frontiers in neuroscience. vol 18. 2024-06-14. PMID:38872942. |
the medial prefrontal cortex (mpfc), amygdala (amyg), and nucleus accumbens (nac) have been identified as critical players in the social preference of individuals with asd. |
2024-06-14 |
2024-06-16 |
Not clear |
| Pan Xu, Gyeongah Park, Xiaoqian Sun, Qian Ge, Zhen Jin, Chien-Hsien Lai, Xiaojie Liu, Qingsong Liu, Rahul Simha, Chen Zeng, Jianyang Du, Hui L. Different emotional states engage distinct descending pathways from the prefrontal cortex. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853906. |
using in vivo calcium imaging, electrophysiology, and optogenetics, we examined neural circuit dynamics in the medial prefrontal cortex (mpfc), targeting two key areas: the basal lateral amygdala (bla) and nucleus accumbens (nac). |
2024-06-10 |
2024-06-14 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
zl006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. |
2024-06-08 |
2024-06-11 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
in this study, we employed a robust viral tracing technique to identify the alteration of the neural pathway connecting the medial prefrontal cortex to the basolateral amygdala, and we observed the disruptions in neuronal projections between the medial prefrontal cortex and the basolateral amygdala following closed head injury. |
2024-06-08 |
2024-06-11 |
Not clear |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
specifically, zl006 effectively mitigates the disruptions in neuronal projections from the medial prefrontal cortex to basolateral amygdala induced by closed head injury. |
2024-06-08 |
2024-06-11 |
Not clear |
| Diana Chan, Kathryn D Baker, Rick Richardso. The impact of chronic fluoxetine treatment in adolescence or adulthood on context fear memory and perineuronal nets. Developmental psychobiology. vol 66. issue 5. 2024-05-29. PMID:38807259. |
here, we investigated the effect of fluoxetine exposure during adolescence or adulthood on context fear memory and pnns in the basolateral amygdala (bla), the ca1 subregion of the hippocampus, and the medial prefrontal cortex in rats. |
2024-05-29 |
2024-06-03 |
rat |
| Giulia Poggi, Federica Klaus, Christopher R Pryc. Pathophysiology in cortico-amygdala circuits and excessive aversion processing: the role of oligodendrocytes and myelination. Brain communications. vol 6. issue 3. 2024-05-08. PMID:38712320. |
here, we assess the comparative evidence for: (i) anterior cingulate/medial prefrontal cortex<->amygdala bidirectional neural circuits as major contributors to aversive stimulus processing; (ii) structural and functional changes in anterior cingulate cortex<->amygdala circuit associated with excessive aversion processing in stress-related neuropsychiatric disorders, and in medial prefrontal cortex<->amygdala circuit in rodent models of chronic stress-induced increased aversion reactivity; and (iii) altered status of oligodendrocytes and their oligodendrocyte lineage cells and myelination in anterior cingulate/medial prefrontal cortex<->amygdala circuits in stress-related neuropsychiatric disorders and stress models. |
2024-05-08 |
2024-05-27 |
human |